thymidine has been researched along with Angiogenesis, Pathologic in 42 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " We show that thymidine induces oxidative stress in TP-overexpressing carcinoma cells, promoting secretion of the stress-induced angiogenic factors vascular endothelial growth factor and interleukin-8, and inducing matrix metalloproteinase-1." | 7.70 | Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors. ( Bicknell, R; Brown, NS; Fujiyama, C; Harris, AL; Jones, A, 2000) |
| "Fusarochromanone is a toxic metabolite produced by Fusarium equiseti, a fungus present in decaying cereal plants in northern latitudes; it has been detected in various food grains." | 5.34 | Inhibitory effects of fusarochromanone on melanoma growth. ( Culberson, C; Dréau, D; Foster, M; Hogg, M; Nunes, P; Wuthier, RE, 2007) |
| " We show that thymidine induces oxidative stress in TP-overexpressing carcinoma cells, promoting secretion of the stress-induced angiogenic factors vascular endothelial growth factor and interleukin-8, and inducing matrix metalloproteinase-1." | 3.70 | Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors. ( Bicknell, R; Brown, NS; Fujiyama, C; Harris, AL; Jones, A, 2000) |
| "In many cancers TP is expressed at high levels and promotes thymidine catabolism, ultimately generating 2-deoxyribose (2dDR) that can support multiple procancer processes, including glycation of proteins, alternative metabolism, extracellular matrix remodeling, and angiogenesis." | 2.82 | Multifunctional role of thymidine phosphorylase in cancer. ( Reigan, P; Warfield, BM, 2022) |
| "TP is overexpressed in various tumors and plays an important role in angiogenesis, tumor growth, invasion and metastasis." | 2.42 | The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression. ( Akiyama, S; Furukawa, T; Haraguchi, M; Nakajima, Y; Shimaoka, S; Sumizawa, T; Takebayashi, Y, 2004) |
| "Fusarochromanone is a toxic metabolite produced by Fusarium equiseti, a fungus present in decaying cereal plants in northern latitudes; it has been detected in various food grains." | 1.34 | Inhibitory effects of fusarochromanone on melanoma growth. ( Culberson, C; Dréau, D; Foster, M; Hogg, M; Nunes, P; Wuthier, RE, 2007) |
| "Rosiglitazone-treated human umbilical vein endothelial cells were analyzed for growth rate by use of cell number counting, 3-[4,5-Dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide assay as well as 3H-thymidine incorporation." | 1.33 | Rosiglitazone inhibits endothelial proliferation and angiogenesis. ( Chou, FP; Lin, TM; Ou, HC; Sheu, WH; Yang, CH, 2006) |
| "Terbinafine was not cytotoxic at a concentration of 120 microM, indicating that it may have an inhibitory effect on the cell proliferation in HUVEC." | 1.32 | Inhibition of human vascular endothelial cells proliferation by terbinafine. ( Chen, CT; Ho, PY; Ho, YS; Lee, WS; Liang, YC, 2004) |
| "Multiple myeloma is a B-cell cancer characterized by the proliferation of malignant plasma cells in the bone marrow, increased angiogenesis, and the development of osteolytic bone disease." | 1.32 | Multifunctional role of matrix metalloproteinases in multiple myeloma: a study in the 5T2MM mouse model. ( Asosingh, K; Blacher, S; Carron, C; Croucher, PI; De Bruyne, E; De Leenheer, E; De Raeve, H; Devy, L; Noël, A; Van Camp, B; Van Riet, I; Van Valckenborgh, E; Vanderkerken, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (16.67) | 18.7374 |
| 1990's | 13 (30.95) | 18.2507 |
| 2000's | 19 (45.24) | 29.6817 |
| 2010's | 2 (4.76) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Warfield, BM | 1 |
| Reigan, P | 1 |
| Lafontant, PJ | 1 |
| Burns, AR | 1 |
| Grivas, JA | 1 |
| Lesch, MA | 1 |
| Lala, TD | 1 |
| Reuter, SP | 1 |
| Field, LJ | 1 |
| Frounfelter, TD | 1 |
| Botelho, MF | 1 |
| Abrantes, AM | 1 |
| Nagy, JA | 1 |
| Vasile, E | 1 |
| Feng, D | 1 |
| Sundberg, C | 1 |
| Brown, LF | 1 |
| Detmar, MJ | 1 |
| Lawitts, JA | 1 |
| Benjamin, L | 1 |
| Tan, X | 1 |
| Manseau, EJ | 1 |
| Dvorak, AM | 1 |
| Dvorak, HF | 1 |
| Yamagishi, S | 1 |
| Amano, S | 1 |
| Inagaki, Y | 1 |
| Okamoto, T | 1 |
| Takeuchi, M | 1 |
| Inoue, H | 1 |
| Ho, PY | 1 |
| Liang, YC | 1 |
| Ho, YS | 1 |
| Chen, CT | 1 |
| Lee, WS | 1 |
| Van Valckenborgh, E | 1 |
| Croucher, PI | 1 |
| De Raeve, H | 1 |
| Carron, C | 1 |
| De Leenheer, E | 1 |
| Blacher, S | 1 |
| Devy, L | 1 |
| Noël, A | 1 |
| De Bruyne, E | 1 |
| Asosingh, K | 1 |
| Van Riet, I | 1 |
| Van Camp, B | 1 |
| Vanderkerken, K | 1 |
| Akiyama, S | 1 |
| Furukawa, T | 1 |
| Sumizawa, T | 1 |
| Takebayashi, Y | 1 |
| Nakajima, Y | 1 |
| Shimaoka, S | 1 |
| Haraguchi, M | 1 |
| Pan, SL | 1 |
| Guh, JH | 1 |
| Peng, CY | 1 |
| Wang, SW | 1 |
| Chang, YL | 1 |
| Cheng, FC | 1 |
| Chang, JH | 1 |
| Kuo, SC | 1 |
| Lee, FY | 1 |
| Teng, CM | 1 |
| Liu, ES | 1 |
| Shin, VY | 1 |
| Ye, YN | 1 |
| Luo, JC | 1 |
| Wu, WK | 1 |
| Cho, CH | 1 |
| Emura, T | 1 |
| Suzuki, N | 1 |
| Fujioka, A | 1 |
| Ohshimo, H | 1 |
| Fukushima, M | 1 |
| Pala, L | 1 |
| Cresci, B | 1 |
| Manuelli, C | 1 |
| Maggi, E | 1 |
| Yamaguchi, YF | 1 |
| Cappugi, P | 1 |
| Rotella, CM | 1 |
| Giannini, S | 1 |
| Meyer, RD | 1 |
| Mohammadi, M | 1 |
| Rahimi, N | 1 |
| Sheu, WH | 1 |
| Ou, HC | 1 |
| Chou, FP | 1 |
| Lin, TM | 1 |
| Yang, CH | 1 |
| Fiszman, G | 1 |
| Cattaneo, V | 1 |
| de la Torre, E | 1 |
| Español, A | 1 |
| Colombo, L | 1 |
| Sacerdote de Lustig, E | 1 |
| Sales, ME | 1 |
| Dréau, D | 1 |
| Foster, M | 1 |
| Hogg, M | 1 |
| Culberson, C | 1 |
| Nunes, P | 1 |
| Wuthier, RE | 1 |
| Glaser, BM | 1 |
| D'Amore, PA | 1 |
| Michels, RG | 1 |
| Patz, A | 1 |
| Fenselau, A | 1 |
| Hobson, B | 1 |
| Denekamp, J | 1 |
| Braddock, PS | 1 |
| Hu, DE | 1 |
| Fan, TP | 1 |
| Stratford, IJ | 1 |
| Harris, AL | 2 |
| Bicknell, R | 2 |
| Tang, DG | 1 |
| Renaud, C | 1 |
| Stojakovic, S | 1 |
| Diglio, CA | 1 |
| Porter, A | 1 |
| Honn, KV | 1 |
| Hata, Y | 1 |
| Nakagawa, K | 1 |
| Ishibashi, T | 1 |
| Inomata, H | 1 |
| Ueno, H | 1 |
| Sueishi, K | 2 |
| Tolsma, SS | 1 |
| Volpert, OV | 1 |
| Good, DJ | 1 |
| Frazier, WA | 1 |
| Polverini, PJ | 1 |
| Bouck, N | 1 |
| Murphy, AN | 1 |
| Unsworth, EJ | 1 |
| Stetler-Stevenson, WG | 1 |
| Horowitz, R | 1 |
| Schwartz, EL | 1 |
| Wadler, S | 1 |
| Antoine, N | 1 |
| Daukandt, M | 1 |
| Heinen, E | 1 |
| Simar, LJ | 1 |
| Castronovo, V | 1 |
| Alessandri, G | 1 |
| Cornaglia-Ferraris, P | 1 |
| Gullino, PM | 1 |
| Bonfil, RD | 1 |
| Bustuoabad, OD | 1 |
| Binda, MM | 1 |
| Ogawa, H | 1 |
| Nishihira, J | 1 |
| Sato, Y | 1 |
| Kondo, M | 1 |
| Takahashi, N | 1 |
| Oshima, T | 1 |
| Todo, S | 1 |
| Shao, R | 1 |
| Xia, W | 1 |
| Hung, MC | 1 |
| Brown, NS | 1 |
| Jones, A | 1 |
| Fujiyama, C | 1 |
| Jankowski, J | 1 |
| Hagemann, J | 1 |
| Yoon, MS | 1 |
| van der Giet, M | 1 |
| Stephan, N | 1 |
| Zidek, W | 1 |
| Schlüter, H | 1 |
| Tepel, M | 1 |
| Yu, JC | 1 |
| Lokker, NA | 1 |
| Hollenbach, S | 1 |
| Apatira, M | 1 |
| Li, J | 1 |
| Betz, A | 1 |
| Sedlock, D | 1 |
| Oda, S | 1 |
| Nomoto, Y | 1 |
| Matsuno, K | 1 |
| Ide , S | 1 |
| Tsukuda, E | 1 |
| Giese, NA | 1 |
| Boehle, AS | 1 |
| Kurdow, R | 1 |
| Schulze, M | 1 |
| Kliche, U | 1 |
| Sipos, B | 1 |
| Soondrum, K | 1 |
| Ebrahimnejad, A | 1 |
| Dohrmann, P | 1 |
| Kalthoff, H | 1 |
| Henne-Bruns, D | 1 |
| Neumaier, M | 1 |
| Sakuda, H | 1 |
| Nakashima, Y | 1 |
| Kuriyama, S | 1 |
| Fajardo, LF | 1 |
| Kwan, HH | 1 |
| Kowalski, J | 1 |
| Prionas, SD | 1 |
| Allison, AC | 1 |
| Bassukas, ID | 1 |
| Vester, G | 1 |
| Maurer-Schultze, B | 1 |
| Stewart, R | 1 |
| Nelson, J | 1 |
| Wilson, DJ | 1 |
| Miya, K | 1 |
| Saji, S | 1 |
| Morita, T | 1 |
| Niwa, H | 1 |
| Takao, H | 1 |
| Kunii, Y | 1 |
| Sakata, K | 1 |
| Shiraki, K | 1 |
| Burns, MS | 1 |
| Majewski, S | 1 |
| Tigalonowa, M | 1 |
| Jabłónska, S | 1 |
| Polakowski, I | 1 |
| Janczura, E | 1 |
| Splawinski, J | 1 |
| Michna, M | 1 |
| Palczak, R | 1 |
| Konturek, S | 1 |
| Splawinska, B | 1 |
| Nakayasu, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Anti-VEGF Therapy for Acute Thyroid Eye Disease (AcTED Study)[NCT04311606] | Phase 2 | 24 participants (Anticipated) | Interventional | 2020-11-02 | Recruiting | ||
| Phase I Study Evaluating the Safety of Bevacizumab in Women With a History of Breast Cancer Suffering From Moderate to Severe Upper Extremity Lymphedema[NCT00318513] | Phase 1 | 35 participants | Interventional | Not yet recruiting | |||
| Phase II Trial of TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma[NCT04923529] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for thymidine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Multifunctional role of thymidine phosphorylase in cancer.
Topics: Fluorouracil; Humans; Neoplasms; Neovascularization, Pathologic; Thymidine; Thymidine Phosphorylase | 2022 |
Radiotracers in oncology.
Topics: Amino Acids; Apoptosis; Cell Hypoxia; Cell Transformation, Neoplastic; Drug Resistance, Multiple; Dr | 2012 |
The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.
Topics: Angiogenesis Inducing Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Ce | 2004 |
Modulation of 5-fluorouracil by interferon: a review of potential cellular targets.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Combined Modality Therapy; Fluorouracil; Humans; Interfe | 1995 |
38 other studies available for thymidine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
The giant danio (D. aequipinnatus) as a model of cardiac remodeling and regeneration.
Topics: Animals; Cell Proliferation; Deoxyuridine; Disease Models, Animal; Granulation Tissue; Inflammation; | 2012 |
Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis.
Topics: Adenoviridae; Angiogenesis Inducing Agents; Animals; Endothelial Growth Factors; Female; Intercellul | 2002 |
Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis.
Topics: Adenoviridae; Angiogenesis Inducing Agents; Animals; Endothelial Growth Factors; Female; Intercellul | 2002 |
Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis.
Topics: Adenoviridae; Angiogenesis Inducing Agents; Animals; Endothelial Growth Factors; Female; Intercellul | 2002 |
Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis.
Topics: Adenoviridae; Angiogenesis Inducing Agents; Animals; Endothelial Growth Factors; Female; Intercellul | 2002 |
Pigment epithelium-derived factor inhibits leptin-induced angiogenesis by suppressing vascular endothelial growth factor gene expression through anti-oxidative properties.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Cattle; DNA; Dose-Response Relationship, Drug; Electro | 2003 |
Inhibition of human vascular endothelial cells proliferation by terbinafine.
Topics: Animals; Blotting, Western; Cell Cycle; Cell Division; Cell Line; Chick Embryo; Dose-Response Relati | 2004 |
Multifunctional role of matrix metalloproteinases in multiple myeloma: a study in the 5T2MM mouse model.
Topics: Animals; Annexin A5; Apoptosis; Bone Diseases; Cell Division; Diet; Disease Models, Animal; Enzyme I | 2004 |
YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Blotting, Western; Cell Movement; Cell Prolif | 2005 |
Cyclooxygenase-2 in cancer cells and macrophages induces colon cancer cell growth by cigarette smoke extract.
Topics: Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Complex Mixt | 2005 |
Potentiation of the antitumor activity of alpha, alpha, alpha-trifluorothymidine by the co-administration of an inhibitor of thymidine phosphorylase at a suitable molar ratio in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line, Tumor; Colorectal N | 2005 |
Vascular endothelial growth factor receptor-2 and low affinity VEGF binding sites on human glomerular endothelial cells: Biological effects and advanced glycosilation end products modulation.
Topics: Age Factors; Binding Sites; Blotting, Western; Cells, Cultured; Diabetic Nephropathies; Dose-Respons | 2005 |
A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Blotting, Western; Cell Membrane; Cell Prol | 2006 |
Rosiglitazone inhibits endothelial proliferation and angiogenesis.
Topics: Cell Division; Cell Survival; Cells, Cultured; DNA Replication; Endothelium, Vascular; Humans; Neova | 2006 |
Muscarinic receptors autoantibodies purified from mammary adenocarcinoma-bearing mice sera stimulate tumor progression.
Topics: Adenocarcinoma; Animals; Atropine; Autoantibodies; Blotting, Western; Carbachol; Cell Line, Tumor; C | 2006 |
Inhibitory effects of fusarochromanone on melanoma growth.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Chromones; Humans; Immunohis | 2007 |
Demonstration of vasoproliferative activity from mammalian retina.
Topics: Animals; Cats; Cattle; Cell Division; Chick Embryo; Cornea; Endothelium; Extraembryonic Membranes; F | 1980 |
Endothelial proliferation in tumours and normal tissues: continuous labelling studies.
Topics: Adenocarcinoma; Animals; Cell Count; Cell Division; Endothelium; Female; Mammary Neoplasms, Experime | 1984 |
A structure-activity analysis of antagonism of the growth factor and angiogenic activity of basic fibroblast growth factor by suramin and related polyanions.
Topics: Animals; Capillaries; Cattle; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Endo | 1994 |
12(S)-HETE is a mitogenic factor for microvascular endothelial cells: its potential role in angiogenesis.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Biotin; Cell Division; Cells, Cultured; Clone C | 1995 |
Hypoxia-induced expression of vascular endothelial growth factor by retinal glial cells promotes in vitro angiogenesis.
Topics: Animals; Blotting, Northern; Cattle; Cells, Cultured; Culture Media, Conditioned; Endothelial Growth | 1995 |
Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Corne | 1993 |
Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation.
Topics: Cell Adhesion; Cell Division; Cell Movement; Cells, Cultured; DNA; Endothelium, Vascular; Fibroblast | 1993 |
In vitro and in vivo stimulation of the murine immune system by AGM-1470, a potent angiogenesis inhibitor.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antigens, CD; B-Lymphocytes; Cell Divi | 1996 |
Angiogenic and angiostatic microenvironment in tumors--role of gangliosides.
Topics: Angiogenesis Inducing Agents; Cell Adhesion; Cell Division; Cell Membrane; Collagen; Culture Media; | 1997 |
Antiangiogenesis and apoptosis as mediators of concomitant tumor resistance induced by Calu-6, a human lung carcinoma cell line, in nude mice.
Topics: Animals; Apoptosis; Cell Division; Cell Line; DNA, Neoplasm; Humans; Immunity, Innate; Lung Neoplasm | 1998 |
An antibody for macrophage migration inhibitory factor suppresses tumour growth and inhibits tumour-associated angiogenesis.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Cells, Cultured; Colonic Neoplasms; Endothelium, Va | 2000 |
Inhibition of angiogenesis and induction of apoptosis are involved in E1A-mediated bystander effect and tumor suppression.
Topics: Adenovirus E1A Proteins; Animals; Apoptosis; Cells, Cultured; Coculture Techniques; Female; Humans; | 2000 |
Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
Topics: Carcinoma; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-8; Lym | 2000 |
Increased vascular growth in hemodialysis patients induced by platelet-derived diadenosine polyphosphates.
Topics: Animals; Blood Platelets; Cell Division; Cells, Cultured; Dinucleoside Phosphates; Female; Humans; K | 2001 |
Efficacy of the novel selective platelet-derived growth factor receptor antagonist CT52923 on cellular proliferation, migration, and suppression of neointima following vascular injury.
Topics: Angioplasty, Balloon; Animals; Carotid Artery Injuries; Cell Division; Cell Movement; CHO Cells; Cri | 2001 |
Human endostatin inhibits growth of human non-small-cell lung cancer in a murine xenotransplant model.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line; Cell Movement; Cell Su | 2001 |
Media conditioned by smooth muscle cells cultured in a variety of hypoxic environments stimulates in vitro angiogenesis. A relationship to transforming growth factor-beta 1.
Topics: alpha-Macroglobulins; Animals; Antibodies; Aorta; Aprotinin; Blotting, Northern; Cattle; Cell Divisi | 1992 |
Dual role of tumor necrosis factor-alpha in angiogenesis.
Topics: Animals; Autoradiography; Capillaries; Cell Division; Dose-Response Relationship, Drug; Female; Infu | 1992 |
Cell kinetic studies of endothelial cells in the adenocarcinoma EO 771 and the effect of cyclophosphamide.
Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Division; Cyclophosphamide; Endothelium, Vascular; Mice; M | 1990 |
Growth of the chick area vasculosa in ovo and in shell-less culture.
Topics: Animals; Cell Division; Chick Embryo; Egg Shell; Neovascularization, Pathologic; Thymidine; Vitellin | 1990 |
[Experimental study on the absorption mechanism of cryo-necrotized tumor antigens].
Topics: Absorption; Animals; Antigens, Neoplasm; Cryosurgery; Female; Neoplasms, Experimental; Neovasculariz | 1986 |
Neovascularization in urethane rat retinopathy demonstrated by thymidine labelling.
Topics: Animals; Autoradiography; Histological Techniques; Neovascularization, Pathologic; Rats; Rats, Inbre | 1986 |
Serum samples from patients with active psoriasis enhance lymphocyte-induced angiogenesis and modulate endothelial cell proliferation.
Topics: Cell Division; Ceruloplasmin; Endothelium; Female; Humans; Lymphocytes; Male; Neovascularization, Pa | 1987 |
Angiogenesis: quantitative assessment by the chick chorioallantoic membrane assay.
Topics: Allantois; Animals; Chick Embryo; Chorion; DNA; Epidermal Growth Factor; Extraembryonic Membranes; F | 1988 |
Origin of pericytes in neovascularization of rat cornea.
Topics: Animals; Autoradiography; Connective Tissue; Cornea; Corneal Stroma; Microscopy, Electron; Neovascul | 1988 |