thymidine has been researched along with Anemia, Megaloblastic in 24 studies
Anemia, Megaloblastic: A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") with the cobalamin D variant of congenital methylmalonic aciduria-homocystinuria, whose previously reported lack of megaloblastic anemia conflicted with current concepts of cobalamin's role in DNA synthesis and the "methyltetrahydrofolate (MTHF) trap" hypothesis." | 7.66 | Abnormal deoxyuridine suppression test in congenital methylmalonic aciduria-homocystinuria without megaloblastic anemia: divergent biochemical and morphological bone marrow manifestations of disordered cobalamin metabolism in man. ( Carmel, R; Goodman, SI, 1982) |
| " Neutropenia following prolonged inhalation of nitrous oxide seems to be caused by a different mechanism, in which the cobalt in B12 is oxidised to the trivalent form by chemical reaction with nitrous oxide." | 4.76 | Anesthesia and the leucocyte. ( Nunn, JF, 1979) |
| ") with the cobalamin D variant of congenital methylmalonic aciduria-homocystinuria, whose previously reported lack of megaloblastic anemia conflicted with current concepts of cobalamin's role in DNA synthesis and the "methyltetrahydrofolate (MTHF) trap" hypothesis." | 3.66 | Abnormal deoxyuridine suppression test in congenital methylmalonic aciduria-homocystinuria without megaloblastic anemia: divergent biochemical and morphological bone marrow manifestations of disordered cobalamin metabolism in man. ( Carmel, R; Goodman, SI, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (95.83) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SPRAY, GH | 1 |
| WITTS, LJ | 1 |
| Burman, JF | 1 |
| Mollin, DL | 1 |
| Wickramasinghe, SN | 1 |
| Saunders, JE | 1 |
| Das, KC | 1 |
| Garewal, G | 1 |
| Mohanty, D | 1 |
| Kano, Y | 1 |
| Sakamoto, S | 1 |
| Hida, K | 1 |
| Suda, K | 1 |
| Takaku, F | 1 |
| Carmel, R | 2 |
| Goodman, SI | 2 |
| Iwata, N | 2 |
| Omine, M | 2 |
| Yamauchi, H | 2 |
| Maekawa, T | 2 |
| Gimferrer, E | 1 |
| Guarner, C | 1 |
| Balanzó, J | 1 |
| Ayats, R | 1 |
| Fábrega, J | 1 |
| Baiget, M | 1 |
| Pujol, N | 1 |
| Presa, F | 1 |
| Simón, X | 1 |
| Altés, R | 1 |
| Chanarin, I | 4 |
| Deacon, R | 3 |
| Perry, J | 3 |
| Lumb, M | 3 |
| Bedros, AA | 1 |
| Mace, JW | 1 |
| Holden, L | 1 |
| Hoffbrand, AV | 2 |
| Tattersall, MH | 1 |
| Koury, MJ | 1 |
| Horne, DW | 1 |
| Brown, ZA | 1 |
| Pietenpol, JA | 1 |
| Blount, BC | 1 |
| Ames, BN | 1 |
| Hard, R | 1 |
| Koury, ST | 1 |
| Taguchi, H | 2 |
| Stafford, DM | 1 |
| Zittoun, J | 1 |
| Zittoun, R | 1 |
| Marquet, J | 1 |
| Bilski-Pasquier, G | 1 |
| Sultan, C | 1 |
| Ganeshaguru, K | 1 |
| Nunn, JF | 1 |
| Van Der Weyden, MB | 1 |
| Rickard, KA | 1 |
| Brown, RD | 1 |
| Dunleavy, L | 1 |
| Robin, H | 1 |
| Kronenberg, H | 1 |
| Schwarz, MA | 1 |
| Firkin, BG | 1 |
| Karasawa, M | 1 |
| Yatabe, H | 1 |
| Tsukamoto, N | 1 |
| Katahira, H | 1 |
| Sugita, Y | 1 |
| Bamezai, R | 1 |
| Shiraishi, Y | 1 |
| Keller, R | 1 |
| Lindstrand, K | 1 |
| Nordén, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Folates in the Care of the Male Infertility[NCT01407432] | Phase 3 | 162 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thymidine and Anemia, Megaloblastic
| Article | Year |
|---|---|
Anesthesia and the leucocyte.
Topics: Anemia, Megaloblastic; Anesthetics; Animals; Bone Marrow; Cell Movement; Chemotaxis, Leukocyte; Halo | 1979 |
Cobalamin-folate interrelations.
Topics: Anemia, Megaloblastic; Animals; Central Nervous System Diseases; Coenzymes; Folic Acid; Folic Acid D | 1989 |
22 other studies available for thymidine and Anemia, Megaloblastic
| Article | Year |
|---|---|
Thymidine in megaloblastic anaemia.
Topics: Anemia; Anemia, Megaloblastic; Anemia, Pernicious; Nucleosides; Nucleotides; Thymidine | 1958 |
The value of the deoxyuridine suppression test in megaloblastic anaemia.
Topics: Anemia, Megaloblastic; Antimetabolites; Deoxyuridine; Folic Acid Deficiency; Humans; Predictive Valu | 1978 |
Incorporation of radioactive precursors into the nucleic acids of bone marrow cells from patients wtih vitamin B12 or folate deficiency.
Topics: Anemia, Megaloblastic; Bone Marrow; Carbon Radioisotopes; DNA; Folic Acid Deficiency; Humans; In Vit | 1980 |
Derangement of DNA synthesis in erythroleukaemia. Normal deoxyuridine suppression and impaired thymidine incorporation in bone marrow culture.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyuridine; DNA; Female; F | 1980 |
5-Methyltetrahydrofolate related enzymes and DNA polymerase alpha activities in bone marrow cells from patients with vitamin B12 deficient megaloblastic anemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase | 1982 |
Abnormal deoxyuridine suppression test in congenital methylmalonic aciduria-homocystinuria without megaloblastic anemia: divergent biochemical and morphological bone marrow manifestations of disordered cobalamin metabolism in man.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Bone Marrow; Deoxyuridine; Homocystinuria; Humans; Male; M | 1982 |
Characteristic abnormality of deoxyribonucleoside triphosphate metabolism in megaloblastic anemia.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyribonucleosides; Deoxyuridine; Humans; | 1982 |
[Macrocytosis in the liver patient: study of blood folate and vitamin B 12, and thymidine synthesis in hematopoietic cells].
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Folic Acid; Hematopoietic Stem Cells; Huma | 1982 |
How vitamin B12 acts.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Animals; Folic Acid; Humans; Methionine; Pteroylpolygluta | 1981 |
The effect of folate analogues on the thymidine utilization by human and rat marrow cells and the effect on the deoxyuridine suppression test.
Topics: Anemia, Megaloblastic; Animals; Bone Marrow; Deoxyuridine; Folic Acid; Humans; Male; Rats; Rats, Inb | 1981 |
Congenital methylmalonic aciduria--homocystinuria with megaloblastic anemia: observations on response to hydroxocobalamin and on the effect of homocysteine and methionine on the deoxyuridine suppression test.
Topics: Anemia, Megaloblastic; Deoxyuridine; DNA; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobal | 1980 |
Thymidine concentrations in human sera: variations in patients with leukaemia and megaloblastic anaemia.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Humans; Leukemia; Lymphoma; Radioimmunoassay; Thymidine | 1980 |
Apoptosis of late-stage erythroblasts in megaloblastic anemia: association with DNA damage and macrocyte production.
Topics: Anemia, Megaloblastic; Animals; Apoptosis; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; C | 1997 |
Deoxyuridine suppression test: a comparison of two methods and effect of thymidine on the incorporation of 3H-deoxyuridine into DNA in human bone marrow cells.
Topics: Anemia, Megaloblastic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Depression, Chemical; DNA; Dose | 1977 |
[Anaemia induced by vitamin B12 or folate deficiency: diagnostic value of the "dU suppression" test (author's transl)].
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Sideroblastic; Bone Marrow; Deoxyuridine; | 1978 |
The effect of deoxyuridine, vitamin B12, folate and alcohol on the uptake of thymidine and on the deoxynucleoside triphosphate concentrations in normal and megaloblastic cells.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyadenine Nucleotides; D | 1978 |
Deoxyuridine metabolism in human megaloblastic marrow cells.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid De | 1979 |
The bone marrow colony forming cell in megaloblastic anaemia and iron deficiency anaemia.
Topics: Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Bone Marrow Cells; Cell | 1975 |
Chloramphenicol-a possible role in the treatment of leukaemia?
Topics: Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Megaloblastic; Bone Marrow; Chloramphenicol; Deoxyur | 1976 |
[Deoxyuridine suppression test. A modified method and specificity in megaloblastic anemia].
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Deoxyuridine; Diagnosis, Differential; Humans; Myelodyspl | 1987 |
Centromere spreading in a case of megaloblastic anemia "cured" under TC 199 culture conditions.
Topics: Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Centromere; Chromosom | 1986 |
Labelling of lymphocyte nuclei and chromosomes with tritiated thymidine in megaloblastic anemia.
Topics: Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Autoradiography; Bone Marrow; Bone Marrow Cells; Ce | 1972 |