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thymidine and Anemia, Macrocytic

thymidine has been researched along with Anemia, Macrocytic in 39 studies

Anemia, Macrocytic: Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).

Research Excerpts

ExcerptRelevanceReference
" First-generation NRTIs are associated with mitochondrial toxicity in patients, mainly due to inhibition of human DNA polymerase γ (hDNA polγ) that manifests as adverse events such as lipodystrophy, lactic acidosis, myopathy, cardiomyopathy, or nephropathy in patients."1.40Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy. ( Dara, H; Frank, S; Marc, D; Mausumee, G; Michael, G; Sanderson, TP; Shawn, C; Soleil, PM; Zhao, Y, 2014)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199038 (97.44)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (2.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mausumee, G1
Frank, S1
Shawn, C1
Dara, H1
Zhao, Y1
Soleil, PM1
Sanderson, TP1
Michael, G1
Marc, D1
TENTORI, L1
VIVALDI, G1
FRENKEL, EP1
SKINNER, WN1
SMILEY, JD1
SCHMID, JR1
FRICK, PG1
Kano, Y1
Sakamoto, S1
Hida, K1
Suda, K1
Takaku, F1
Iwata, N2
Omine, M2
Yamauchi, H2
Maekawa, T2
Gimferrer, E1
Guarner, C1
Balanzó, J1
Ayats, R1
Fábrega, J1
Baiget, M1
Pujol, N1
Presa, F1
Simón, X1
Altés, R1
Chanarin, I1
Deacon, R1
Perry, J1
Lumb, M1
Holden, L1
Hoffbrand, AV4
Tattersall, MH1
Zittoun, J1
Zittoun, R1
Marquet, J1
Bilski-Pasquier, G1
Sultan, C1
Ganeshaguru, K1
Van Der Weyden, MB3
Rickard, KA1
Brown, RD1
Dunleavy, L1
Robin, H1
Kronenberg, H1
Kitamura, Y1
Kawata, T1
Okano, K1
Asayama, S1
Seki, M1
Karasawa, M1
Yatabe, H1
Tsukamoto, N1
Katahira, H1
Sugita, Y1
Bamezai, R1
Shiraishi, Y1
Taguchi, H1
Wickramasinghe, SN3
Longland, JE1
Koutts, J1
Cooper, M2
Queisser, W1
Moffatt, B1
Keller, R1
Lindstrand, K1
Nordén, A1
Firkin, BG1
Greenberg, PL1
Schrier, SL1
Herbert, V3
Tisman, G1
Brenner, L1
Tripp, E1
Houlihan, CM1
Scott, JM1
Van der Weyden, M1
Rother, M1
Firkin, B1
Huber, C1
Huber, H1
Stacher, A1
Braunsteiner, H1
Semencheva, EM1
Rodionov, GA1
Kuznetsova, LI1
Bebeshko, VG1
Lampkin, BC1
Pyesmany, A1
Hyman, CB1
Hammond, D1
Müller, D2
Hartje, J2
Das, KC1
Killmann, SA1
Bock, HE1
Wilmanns, W1
Yoshida, Y1
Todo, A2
Shirakawa, S1
Wakisaka, G1
Uchino, H1
Cooper, EH1
Chalmers, DG1
Waxman, S2
Metz, J1
Sullivan, LW1

Reviews

1 review available for thymidine and Anemia, Macrocytic

ArticleYear
[The combined application of cytophotometric and autoradiographic methods in the study of the proliferation of normal and distrubed human haemopoietic cell systems (author's transl)].
    Klinische Wochenschrift, 1973, Jul-15, Volume: 51, Issue:14

    Topics: Anemia, Aplastic; Anemia, Hemolytic, Congenital; Anemia, Macrocytic; Autoradiography; Cell Division;

1973

Other Studies

38 other studies available for thymidine and Anemia, Macrocytic

ArticleYear
Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy.
    International journal of toxicology, 2014, Volume: 33, Issue:3

    Topics: Anemia, Macrocytic; Animals; Anti-HIV Agents; Biotransformation; Dose-Response Relationship, Drug; D

2014
[Thymidine in experimental macrocytic anemia in the folic acid deficient rat].
    Rendiconti - Istituto superiore di sanita, 1953, Volume: 16, Issue:10-11-12

    Topics: Anemia; Anemia, Macrocytic; Animals; Folic Acid; Humans; Rats; Thymidine; Thymine

1953
STUDIES ON A METABOLIC DEFECT INDUCED BY HYDROXYUREA (NSC-32065).
    Cancer chemotherapy reports, 1964, Volume: 40

    Topics: Anemia; Anemia, Macrocytic; Animals; Antineoplastic Agents; Bone Marrow Cells; Cattle; Cytosine Nucl

1964
[NUTRITIONAL FOLIC ACID DEFICIENCY ANEMIA. STUDIES WITH H3-LABELLED FOLIC ACID, CO58-LABELLED VITAMIN B12, FE59- AND H3-LABELLED THYMIDIN].
    Schweizerische medizinische Wochenschrift, 1965, May-01, Volume: 95

    Topics: Anemia; Anemia, Macrocytic; Corrinoids; Folic Acid; Folic Acid Deficiency; Humans; Radioisotopes; Th

1965
5-Methyltetrahydrofolate related enzymes and DNA polymerase alpha activities in bone marrow cells from patients with vitamin B12 deficient megaloblastic anemia.
    Blood, 1982, Volume: 59, Issue:4

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase

1982
Characteristic abnormality of deoxyribonucleoside triphosphate metabolism in megaloblastic anemia.
    Blood, 1982, Volume: 60, Issue:4

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyribonucleosides; Deoxyuridine; Humans;

1982
[Macrocytosis in the liver patient: study of blood folate and vitamin B 12, and thymidine synthesis in hematopoietic cells].
    Sangre, 1982, Volume: 27, Issue:4-B

    Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Folic Acid; Hematopoietic Stem Cells; Huma

1982
How vitamin B12 acts.
    British journal of haematology, 1981, Volume: 47, Issue:4

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Animals; Folic Acid; Humans; Methionine; Pteroylpolygluta

1981
Thymidine concentrations in human sera: variations in patients with leukaemia and megaloblastic anaemia.
    European journal of cancer, 1980, Volume: 16, Issue:1

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Humans; Leukemia; Lymphoma; Radioimmunoassay; Thymidine

1980
[Anaemia induced by vitamin B12 or folate deficiency: diagnostic value of the "dU suppression" test (author's transl)].
    La Nouvelle presse medicale, 1978, May-13, Volume: 7, Issue:19

    Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Sideroblastic; Bone Marrow; Deoxyuridine;

1978
The effect of deoxyuridine, vitamin B12, folate and alcohol on the uptake of thymidine and on the deoxynucleoside triphosphate concentrations in normal and megaloblastic cells.
    British journal of haematology, 1978, Volume: 40, Issue:1

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyadenine Nucleotides; D

1978
Deoxyuridine metabolism in human megaloblastic marrow cells.
    Scandinavian journal of haematology, 1979, Volume: 23, Issue:1

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid De

1979
The bone marrow colony forming cell in megaloblastic anaemia and iron deficiency anaemia.
    Australian and New Zealand journal of medicine, 1975, Volume: 5, Issue:5

    Topics: Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Bone Marrow Cells; Cell

1975
Colony-forming ability of bone marrow cells of W anaemic mice on macrophage layer formed in peritoneal cavity of mice.
    Cell and tissue kinetics, 1975, Volume: 8, Issue:2

    Topics: Anemia, Macrocytic; Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Erythropoiesis; Genotype

1975
[Deoxyuridine suppression test. A modified method and specificity in megaloblastic anemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:9

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Deoxyuridine; Diagnosis, Differential; Humans; Myelodyspl

1987
Centromere spreading in a case of megaloblastic anemia "cured" under TC 199 culture conditions.
    Cancer genetics and cytogenetics, 1986, Feb-15, Volume: 20, Issue:3-4

    Topics: Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Centromere; Chromosom

1986
Rate of incorporation of tritiated thymidine into DNA of normoblastic and megaloblastic bone marrow cells in vitro.
    Acta haematologica, 1974, Volume: 52, Issue:1

    Topics: Alcoholism; Anemia, Hypochromic; Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; D

1974
Effect ot trimethoprim on folate metabolism in human bone marrow.
    Australian and New Zealand journal of medicine, 1973, Volume: 3, Issue:3

    Topics: Adult; Anemia, Macrocytic; Anti-Infective Agents; Bone Marrow; Culture Techniques; Deoxyuridine; Dep

1973
DNA synthesis during human eosinopoiesis.
    Acta haematologica, 1972, Volume: 48, Issue:3

    Topics: Anemia, Macrocytic; Autoradiography; Bone Marrow; Bone Marrow Cells; DNA; Eosinophilia; Eosinophils;

1972
Labelling of lymphocyte nuclei and chromosomes with tritiated thymidine in megaloblastic anemia.
    Hereditas, 1972, Volume: 71, Issue:2

    Topics: Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Autoradiography; Bone Marrow; Bone Marrow Cells; Ce

1972
Defective DNA synthesis in human megaloblastic bone marrow: effects of hydroxy-B 12 5'-deoxyadenosyl-B 12 and methyl-B 12 .
    Blood, 1973, Volume: 41, Issue:2

    Topics: Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridin

1973
Granulopoiesis in neutropenic disorders.
    Blood, 1973, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Cell D

1973
The dU suppression test using 125 I-UdR to define biochemical megaloblastosis.
    British journal of haematology, 1973, Volume: 24, Issue:6

    Topics: Anemia, Macrocytic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; In Vi

1973
Studies on the uptake of synthetic conjugated folates by human marrow cells.
    Blood, 1973, Volume: 42, Issue:1

    Topics: Anemia, Macrocytic; Biological Transport; Bone Marrow; Bone Marrow Cells; Coenzymes; Deoxyuridine; D

1973
Megaloblastic maturation masked by iron deficiency: a biochemical basis.
    British journal of haematology, 1972, Volume: 22, Issue:3

    Topics: Anemia, Hypochromic; Anemia, Macrocytic; Bone Marrow; Culture Techniques; Deferoxamine; Deoxyuridine

1972
[Autoradiographic and cytophotometric studies on hematopoiesis in primarily refractory and sideroachrestic anemia].
    Blut, 1972, Volume: 24, Issue:3

    Topics: Anemia; Anemia, Macrocytic; Autoradiography; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Diplo

1972
[Mechanism of action on the body of propazin--a compound of the group of symmetrical triazines].
    Biulleten' eksperimental'noi biologii i meditsiny, 1972, Volume: 73, Issue:6

    Topics: Anemia; Anemia, Hypochromic; Anemia, Macrocytic; Animals; Bone Marrow; Female; Male; Promazine; Rabb

1972
Congenital familial megaloblastic anemia.
    Blood, 1971, Volume: 37, Issue:6

    Topics: Anemia, Macrocytic; Bone Marrow; Cobalt Isotopes; Deoxyuridine; Female; Folic Acid; Hemoglobins; Hum

1971
[Formation and fate of "giant metamyelocytes" in megaloblastic anemias].
    Klinische Wochenschrift, 1969, Jan-15, Volume: 47, Issue:2

    Topics: Aged; Anemia, Macrocytic; Autoradiography; Cell Nucleus; DNA; Erythropoiesis; Female; Humans; Leukoc

1969
Lymphocyte transformation in megaloblastic anaemia: morphology and DNA synthesis.
    British journal of haematology, 1970, Volume: 19, Issue:4

    Topics: Anemia, Macrocytic; Anemia, Pernicious; Chromosomes; Culture Techniques; Deoxyuridine; DNA; Folic Ac

1970
Cell classification and kinetic aspects of normoblastic and megaloblastic erythropoiesis.
    Cell and tissue kinetics, 1970, Volume: 3, Issue:3

    Topics: Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow Cells; Cell Count; DNA; Erythrocytes; Erythrocyt

1970
[Thymine nucleotide synthesis and proliferation of bone marrow cells in megaloblastic anemias under the effect of vitamin B 12].
    Klinische Wochenschrift, 1967, Feb-15, Volume: 45, Issue:4

    Topics: Aged; Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; DNA; Erythropoiesis; Female; Hematopoiesis

1967
Proliferation of megaloblasts in pernicious anemia as observed from nucleic acid metabolism.
    Blood, 1968, Volume: 31, Issue:3

    Topics: Anemia, Macrocytic; Anemia, Pernicious; Autoradiography; Bone Marrow Cells; Densitometry; DNA; Eryth

1968
A study of erythropoiesis by combined morphologic, quantitative cytochemical and autoradiographic methods. Normal human bone marrow, vitamin B12 deficiency and iron deficiency anemia.
    Blood, 1968, Volume: 31, Issue:3

    Topics: Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Pernicious; Autoradiography; Bone Marrow; Bone Marr

1968
Proliferation and differentiation of hematopoietic cells in hematologic disorders. 1. In vitro radioautographic study of megaloblast in vitamin B12 and folic acid deficiency.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1968, Volume: 31, Issue:6

    Topics: Adult; Aged; Anemia, Macrocytic; Culture Techniques; Erythrocytes; Folic Acid Deficiency; Hematopoie

1968
Defective DNA synthesis in human megaloblastic bone marrow: effects of homocysteine and methionine.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:2

    Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow; Deoxyuridine; DNA; Folic Acid Deficienc

1969
Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow.
    The New England journal of medicine, 1969, Jun-12, Volume: 280, Issue:24

    Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Diseases; Chorioretinitis; Culture Techniques; Deoxyuri

1969
Of men, malaria and megaloblasts.
    The New England journal of medicine, 1969, Jun-12, Volume: 280, Issue:24

    Topics: Anemia, Macrocytic; Bone Marrow Diseases; Folic Acid Antagonists; Humans; Malaria; Pyrimethamine; Th

1969