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thymidine and Anemia, Hypoplastic

thymidine has been researched along with Anemia, Hypoplastic in 38 studies

Research Excerpts

ExcerptRelevanceReference
"Uptake of 3H-thymidine and its incorporation into DNA was studied in fibroblastic cell lines derived from normal individuals, patients with Fanconi anemia, and those heterozygous for this genetic trait."7.66Reduced uptake and incorporation of 3H-thymidine in Fanconi anemia fibroblasts. ( Gunnell, M; Lubiniecki, AS; Shoyab, M, 1981)
"The time course of DNA repair, using (3H)thymidine uptake as parameter, was measured during 8 h after a single exposure to 2, 8, and 16 UV-C J/m2 in lymphocytes of 8 cancer patients, 1 xeroderma pigmentosum patient and 10 controls."3.68Differences in the kinetics of DNA repair in cancer patients and healthy controls. ( Kovacs, E; Langemann, H, 1991)
"Uptake of 3H-thymidine and its incorporation into DNA was studied in fibroblastic cell lines derived from normal individuals, patients with Fanconi anemia, and those heterozygous for this genetic trait."3.66Reduced uptake and incorporation of 3H-thymidine in Fanconi anemia fibroblasts. ( Gunnell, M; Lubiniecki, AS; Shoyab, M, 1981)
"A variant of this aplastic anemia-prone subgroup (with comparable short survival due to markedly ineffective hematopoiesis, but expressing select preleukemic features) exhibited reduced numbers (relative to age-matched controls) of highly responsive, UDS-positive marrow blasts (in terms of UDS signal strength and increased to sensitivity 1-beta-D-arabinofuranosylcytosine-induced UDS inhibition)."1.29Chronic radiation-induced alteration in hematopoietic repair during preclinical phases of aplastic anemia and myeloproliferative disease: assessing unscheduled DNA synthesis responses. ( Meyers, SM; Seed, TM, 1993)
"It is suggested that in aplastic anaemia there are different populations of lymphocytes with differing DNA-repair capacity; ALG treatment seems to favour expansion of the normal population, which is associated with improvement of haemopoietic function."1.27Repair of UV-induced DNA damage in aplastic anaemia: changes after treatment with antilymphocyte globulin (ALG). ( Kovacs, E; Nissen, C; Signer, E; Speck, B, 1988)
"In contrast with this, patients with aplastic anaemia have been found to have entirely normal lymphoid cell populations in the peripheral blood and provide no evidence that this condition has an autoimmune basis."1.25Reactive lymphoid cells ('Immunoblasts') in autoimmune and haematological disorders. ( Bacon, PA; Crowther, D; Sewell, RL, 1975)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199035 (92.11)18.7374
1990's3 (7.89)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
COOPER, IA2
FIRKIN, BG2
Shoyab, M1
Gunnell, M1
Lubiniecki, AS1
Seed, TM1
Meyers, SM1
Karp, JE1
Schacter, LP1
Burke, PJ2
Remsen, JF1
Cerutti, PA1
Elmore, E1
Swift, M1
Bacon, PA1
Sewell, RL1
Crowther, D1
Kovacs, E2
Langemann, H1
Kenne, K1
Akerblom, L1
Poulter, L1
Adams, JA1
Knight, I1
McCarthy, DM1
Barrett, AJ1
Mirrakhimov, MM1
Raimzhanov, AR1
Nissen, C1
Speck, B3
Signer, E1
Golde, DW2
Schooley, JC1
Cline, MJ2
Meuwissen, HJ1
Gatti, RA1
Terasaki, PI1
Hong, R1
Good, RA1
Twomey, JJ1
Douglass, CC1
Sharkey, O1
Rudolph, RH1
Mickelson, E1
Petersons, J1
Thomas, ED1
Sasportes, M1
Bernard, A1
Dausset, J1
Diggs, CH1
Owens, AH1
Müller, D1
Reichert, E1
Lang, HD1
Orywall, D1
Queisser, W2
Skårberg, KO1
Kurz, R1
Huber, C1
Reinken, L1
Huber, H1
Whitcomb, ME1
Rocklin, RE1
Poon, PK1
O'Brien, RL1
Parker, JW1
Moeschlin, S1
Jaroshevsky, AJ1
Plotkin, VJ1
Shekter, CJ1
Flad, HD1
Hochapfel, G1
Fliedner, TM1
Heimpel, H2
Spiertz, E1
Jost, E1
Wong, KY1
Hug, G1
Lampkin, BC1
Kissling, M1
Udupa, KB1
Okamura, H1
Reissmann, KR1
Sanchez Fayos, J1
Outeirino, J1
Paniagua, G1
Martinez, MT1
Fitzgerald, PH1
Hamer, JW1
Matsuya, Y1
Green, H1
Basilico, C1
Nagao, T1
Mauer, AM1
Lundmark, KM1

Reviews

1 review available for thymidine and Anemia, Hypoplastic

ArticleYear
[The combined application of cytophotometric and autoradiographic methods in the study of the proliferation of normal and distrubed human haemopoietic cell systems (author's transl)].
    Klinische Wochenschrift, 1973, Jul-15, Volume: 51, Issue:14

    Topics: Anemia, Aplastic; Anemia, Hemolytic, Congenital; Anemia, Macrocytic; Autoradiography; Cell Division;

1973

Other Studies

37 other studies available for thymidine and Anemia, Hypoplastic

ArticleYear
THE PRESENCE OF DEOXYRIBONUCLEIC ACID (DNA) SYNTHESIZING CELLS IN PATIENTS WITH REFRACTORY ANEMIA.
    Blood, 1964, Volume: 24

    Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Refractory; Autoradiography; DNA; Geriatrics; H

1964
DEOXYRIBONUCLEIC ACID SYNTHESIZING CELLS IN THE PERIPHERAL BLOOD OF PATIENTS WITH "AUTO-IMMUNE" DISORDERS.
    Australasian annals of medicine, 1965, Volume: 14

    Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Rheumatoid; Autoimmune Diseases;

1965
Reduced uptake and incorporation of 3H-thymidine in Fanconi anemia fibroblasts.
    Human genetics, 1981, Volume: 57, Issue:3

    Topics: Anemia, Aplastic; Cell Line; DNA; Fanconi Anemia; Fibroblasts; Heterozygote; Humans; Thymidine

1981
Chronic radiation-induced alteration in hematopoietic repair during preclinical phases of aplastic anemia and myeloproliferative disease: assessing unscheduled DNA synthesis responses.
    Cancer research, 1993, Oct-01, Volume: 53, Issue:19

    Topics: Anemia, Aplastic; Animals; Autoradiography; Bone Marrow; Cell Cycle; Cobalt Radioisotopes; DNA; DNA

1993
Humoral factors in aplastic anemia: relationship of liver dysfunction to lack of serum stimulation of bone marrow growth in vitro.
    Blood, 1978, Volume: 51, Issue:3

    Topics: ABO Blood-Group System; Adolescent; Adult; Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Cell Co

1978
Deficiency of gamma-ray excision repair in skin fibroblasts from patients with Fanconi's anemia.
    Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:7

    Topics: Anemia, Aplastic; Cell Nucleus; Cells, Cultured; DNA; DNA Repair; Fanconi Anemia; Fibroblasts; Gamma

1976
Growth of cultured cells from patients with Fanconi anemia.
    Journal of cellular physiology, 1975, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Anemia, Aplastic; Cell Count; Cell Division; Cells, Cultured; Child; Child, Presc

1975
Reactive lymphoid cells ('Immunoblasts') in autoimmune and haematological disorders.
    Clinical and experimental immunology, 1975, Volume: 19, Issue:2

    Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Leukocyte Count; Lupus Erythem

1975
Differences in the kinetics of DNA repair in cancer patients and healthy controls.
    Oncology, 1991, Volume: 48, Issue:4

    Topics: Anemia, Aplastic; Breast Neoplasms; DNA Repair; Female; Humans; Hydroxyurea; In Vitro Techniques; Ki

1991
Deoxyribonucleoside triphosphate pool levels in three cell strains of human chromosome instability syndromes: ataxia telangiectasia (GM2052), Bloom's syndrome (GM1492), and Fanconi's anemia (GM368).
    Cancer biochemistry biophysics, 1990, Volume: 11, Issue:1

    Topics: Anemia, Aplastic; Ataxia Telangiectasia; Bloom Syndrome; Cell Division; Cell Line; Culture Media; De

1990
Mixed lymphocyte cultures using automated blood cell counters.
    Bone marrow transplantation, 1989, Volume: 4, Issue:6

    Topics: Anemia, Aplastic; Bone Marrow Transplantation; Fanconi Anemia; Humans; Leukemia; Leukocyte Count; Ly

1989
[Proliferation and differentiation of erythroid bone marrow cells in patients with hypoplastic anemia under alpine conditions (based on 3H-thymidine incorporation data)].
    Terapevticheskii arkhiv, 1988, Volume: 60, Issue:5

    Topics: Adaptation, Physiological; Adolescent; Adult; Altitude; Anemia, Aplastic; Autoradiography; Bone Marr

1988
Repair of UV-induced DNA damage in aplastic anaemia: changes after treatment with antilymphocyte globulin (ALG).
    European journal of haematology, 1988, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cell Survival; DNA; DNA Damage; Dose-Resp

1988
Erythropoietin-stimulated proliferation of human red cell precursors in vitro.
    British journal of haematology, 1974, Volume: 28, Issue:1

    Topics: Anemia, Aplastic; Animals; Antibodies; Autoradiography; Cell Differentiation; Cell Division; Cells,

1974
Treatment of lymphopenic hypogammaglobulinemia and bone-marrow aplasia by transplantation of allogeneic marrow. Crucial role of histocompatiility matching.
    The New England journal of medicine, 1969, Sep-25, Volume: 281, Issue:13

    Topics: Agammaglobulinemia; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Transplantation; Carbon Isot

1969
The monocytopenia of aplastic anemia.
    Blood, 1973, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow Examination; Cells, Cultured; Child; Female;

1973
Mixed leukocyte culture utilizing whole blood. A simplified technique.
    Transplantation, 1973, Volume: 15, Issue:6

    Topics: Anemia, Aplastic; Blood; Cobalt Isotopes; Culture Media; Erythrocytes; Histocompatibility Testing; H

1973
Abnormal mixed leucocyte reaction in bone marrow aplasia.
    British medical journal, 1973, Oct-06, Volume: 4, Issue:5883

    Topics: Adult; Agammaglobulinemia; Anemia, Aplastic; Bone Marrow Diseases; Humans; Immunoglobulin A; Immunog

1973
Factors in human serum affecting the proliferation of normal and leukemic cells.
    Cancer research, 1973, Volume: 33, Issue:4

    Topics: Anemia, Aplastic; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Line; Cycloph

1973
Human preleukemia. Identification of a maturation defect in vitro.
    The New England journal of medicine, 1973, May-24, Volume: 288, Issue:21

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division

1973
[Cell cycle and ineffective cell renewal in disturbed granulo- and erythropoiesis. Combined pulse-cytophotometry, feulgen-photometry, 3H-thymidine- autoradiographic and cytogenetic investigations (author's transl)].
    Klinische Wochenschrift, 1974, Apr-15, Volume: 52, Issue:8

    Topics: Adult; Aged; Anemia, Aplastic; Autoradiography; Chromosome Mapping; DNA; Erythropoiesis; Female; Gra

1974
Cellularity and cell proliferation rates in human bone marrow. IV. Studies on bone marrow cellularity and erythrokinetics in hypoproliferative anaemia.
    Acta medica Scandinavica, 1974, Volume: 195, Issue:4

    Topics: Adult; Aged; Anemia, Aplastic; Blood Volume; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Sur

1974
[Congenital dyserythropoietic anaemia type II. II. Autoradiographic, serologic, and vitamin-B 6 -metabolism studies].
    Padiatrie und Padologie, 1973, Volume: 8, Issue:2

    Topics: Anemia; Anemia, Aplastic; Autoradiography; Bone Marrow Examination; Cell Differentiation; Diagnosis,

1973
Transfer factor therapy in a patient with progressive primary tuberculosis.
    Annals of internal medicine, 1973, Volume: 79, Issue:2

    Topics: Adult; Aminosalicylic Acids; Anemia, Aplastic; Cell Migration Inhibition; Ethambutol; Female; Humans

1973
Defective DNA repair in Fanconi's anaemia.
    Nature, 1974, Jul-19, Volume: 250, Issue:463

    Topics: Anemia, Aplastic; Chromosome Aberrations; DNA; DNA Repair; Dose-Response Relationship, Radiation; Fi

1974
Experimental studies on the mechanism of action of benzene on the bone marrow (radioautographic studies using 3H-thymidine).
    Acta haematologica, 1967, Volume: 38, Issue:2

    Topics: Anemia, Aplastic; Animals; Autoradiography; Benzene; Bone Marrow; DNA; Erythropoiesis; Rabbits; Thym

1967
DNA synthesis by erythroblasts in normal man and in disorders of erythropoesis.
    Acta haematologica, 1968, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Anemia, Aplastic; Anemia, Hypochromic; Autoradiography; Bone Marrow Cells; Cultur

1968
[Blastic transformation and DNA synthesis in lymphocyte cultures from patients with aplastic anemia (panmyelopathy)].
    Acta haematologica, 1970, Volume: 44, Issue:1

    Topics: Anemia, Aplastic; Antilymphocyte Serum; Culture Techniques; DNA; Humans; Lectins; Lymphocyte Activat

1970
Proliferation disturbances of erythroblasts in congenital dyserythropoietic anemia type I and II.
    Acta haematologica, 1971, Volume: 45, Issue:2

    Topics: Adult; Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Cell Division; Cytoplasm; DNA; Erythrocytes

1971
Congenital dyserythropoietic anemia type II: ultrastructural and radioautographic studies of blood and bone marrow.
    Blood, 1972, Volume: 39, Issue:1

    Topics: Anemia, Aplastic; Antibodies; Autoradiography; Bone Marrow Examination; Cell Membrane; Cell Survival

1972
Further studies on experimental benzene induced aplastic anemia.
    Blut, 1972, Volume: 25, Issue:2

    Topics: Anemia, Aplastic; Animals; Autoradiography; Benzene; Bone Marrow; Bone Marrow Cells; Bone Marrow Exa

1972
Granulopoiesis during myleran-induced suppression of transplantable hen atopoietic stem cells.
    Blood, 1972, Volume: 39, Issue:3

    Topics: Anemia, Aplastic; Animals; Blood Cell Count; Busulfan; Cell Differentiation; Erythropoiesis; Erythro

1972
[Cytodynamic studies of the erythroblastic bone marrow cell population in chronic hypoplastic pancytopenias. I. Analysis of the proliferative compartment].
    Sangre, 1971, Volume: 16, Issue:3

    Topics: Anemia, Aplastic; Autoradiography; Bone Marrow; Bone Marrow Cells; DNA; Erythrocytes; Erythropoiesis

1971
Primary acquired red cell hypoplasia associated with a clonal chromosomal abnormality and disturbed erythroid proliferation.
    Blood, 1971, Volume: 38, Issue:3

    Topics: Adult; Anemia, Aplastic; Autoradiography; Bone Marrow Examination; Cell Division; Chromosome Aberrat

1971
Properties and uses of human-mouse hybrid cell lines.
    Nature, 1968, Dec-21, Volume: 220, Issue:5173

    Topics: Anemia, Aplastic; Animals; Autoradiography; Child; Chromosomes, Human, 16-18; Culture Media; Culture

1968
Concordance for drug-induced aplastic anemia in identical twins.
    The New England journal of medicine, 1969, Jul-03, Volume: 281, Issue:1

    Topics: Anemia, Aplastic; Blood Transfusion; Bone Marrow Cells; Bone Marrow Examination; Chloramphenicol; Di

1969
Bone marrow cell proliferation in health and in haematological disease during childhood.
    Acta paediatrica Scandinavica, 1966

    Topics: Aging; Agranulocytosis; Anemia, Aplastic; Autoradiography; Blood Cell Count; Bone Marrow; Bone Marro

1966