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thymidine and Adenoma

thymidine has been researched along with Adenoma in 34 studies

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" However, we recently reviewed rectal biopsies from 152 subjects (43 controls, 84 with adenomas, 25 resected for colon cancer) processed for in vitro 3H-thymidine autoradiography, and attempted to correlate various proliferative parameters with clinical and pathological variables by means of multiple regression analysis."4.79Reliability of rectal epithelial kinetic patterns as an intermediate biomarker of colon cancer. ( Anti, M; Armelao, F; Gasbarrini, G; Marra, G; Percesepe, A, 1994)
"Human pituitary adenoma cells and rat pituitary cell line (GH3) were cultured and treated in vitro with octreotide and the broad-spectrum SST agonist SOM230 (pasireotide)."3.73Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours. ( Ciccarelli, E; Czirják, S; Gaia, D; Góth, MI; Grossman, AB; Hanson, MR; Hanzély, Z; Hubina, E; Jordan, S; Khalaf, S; Korbonits, M; Losa, M; Nagy, GM; Nanzer, AM; Papotti, M; Terreni, MR, 2006)
" The effect of inhibition of tyrosine kinase activity on thymidine uptake into cultured human pituitary adenoma cells was studied using two inhibitors, genestein and methyl-2,3-dihydroxycinnamate (MDHC)."3.69Suppression of tyrosine kinase activity inhibits [3H]thymidine uptake in cultured human pituitary tumor cells. ( Jones, TH; Justice, SK; Price, A, 1997)
"In connection with routine endoscopic examinations of 31 patients with familial adenomatosis coli and 28 health kindreds of patients with familial adenomatosis coli we investigated by autoradiography the in vitro incorporation of 3H-thymidine into bioptic mucosal particles from colon and adenomas."3.68[Autoradiography of DNA synthesis in colonic mucosa of patients with familial adenomatosis coli]. ( Irro, F; Jacobasch, KH; Steenbeck, L, 1990)
"The percentage of cells in the S/G2M fraction and the cytosol deoxythymidine kinase activity (TKA) were measured in autonomously functioning thyroid adenomas (AFTA) and paranodular tissue (PNT), with special regard to the impact of the patient's serum TSH concentration on DNA synthesis."3.67Increased deoxyribonucleic acid synthesis of autonomously functioning thyroid adenomas: independent of but further stimulable by thyrotropin. ( Baisch, H; Kremer, B; Müller-Gärtner, HW; Schneider, C; Wiegel, T, 1989)
" injection of caffeine (8, 20, and 40 mg/kg) 3 times weekly for 8 weeks suppressed the development of spontaneous pulmonary adenomas in strain A mice."3.66Inhibiting effect of caffeine on spontaneous and urethan-induced lung tumors in strain A mice. ( Shimkin, MB; Theiss, JC, 1978)
"Inhibition of 5-LOX in an in vivo colon cancer xenograft model inhibited tumor growth compared with that of controls (P < 0."1.35Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model. ( Adrian, TA; Bell, RH; Bentrem, DJ; Ding, XZ; Kennedy, TJ; Melstrom, LG; Rao, SM; Salabat, MR; Strouch, M; Talamonti, MS; Ternent, CA; Witt, RC, 2008)
"Among these, the growth fraction of pituitary adenomas has been determined by different methods, of which the most useful are those performed in archival material."1.30Usefulness of markers of cell proliferation in the management of pituitary adenomas. ( Franzin, A; Giovanelli, M; Losa, M; Mangili, F; Mortini, P; Terreni, MR, 1998)
"In the studies described here, we demonstrated a unique dose-response (concaved upward) to TPA in sparse human cell cultures and a dose-dependent stimulation of cell proliferation in confluent cultures, suggesting a functional difference in putative TPA receptors between these two conditions."1.26Genetic forms of neoplasia in man: a model for the study of tumor promotion in vitro. ( Kopelovich, L, 1982)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199020 (58.82)18.7374
1990's9 (26.47)18.2507
2000's5 (14.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Florio, T1
Barbieri, F1
Spaziante, R1
Zona, G1
Hofland, LJ1
van Koetsveld, PM1
Feelders, RA1
Stalla, GK1
Theodoropoulou, M1
Culler, MD1
Dong, J1
Taylor, JE1
Moreau, JP1
Saveanu, A1
Gunz, G1
Dufour, H1
Jaquet, P1
Melstrom, LG1
Bentrem, DJ1
Salabat, MR1
Kennedy, TJ1
Ding, XZ1
Strouch, M1
Rao, SM1
Witt, RC1
Ternent, CA1
Talamonti, MS1
Bell, RH1
Adrian, TA1
Hubina, E1
Nanzer, AM1
Hanson, MR1
Ciccarelli, E1
Losa, M2
Gaia, D1
Papotti, M1
Terreni, MR2
Khalaf, S1
Jordan, S1
Czirják, S1
Hanzély, Z1
Nagy, GM1
Góth, MI1
Grossman, AB1
Korbonits, M1
Shimizu, T1
Kopelovich, L1
Caronti, B1
Palladini, G1
Calderaro, C1
Bevilacqua, MG1
Petrangeli, E1
Esposito, V1
Tamburrano, G1
Gulino, A1
Jaffrain-Rea, ML1
Anti, M1
Marra, G1
Percesepe, A1
Armelao, F1
Gasbarrini, G1
Alberts, DS1
Einspahr, J1
Aickin, M1
Hixson, L1
Earnest, D1
Roe, D1
Powell, M1
Saxe, A1
Gibson, G1
Jones, TH1
Justice, SK1
Price, A1
Ander, SJ1
Blomkvist, LM1
Mölne, JC1
Johansson, KJ1
Smeds, SP1
Franzin, A1
Mortini, P1
Mangili, F1
Giovanelli, M1
Danila, DC1
Inder, WJ1
Zhang, X1
Alexander, JM1
Swearingen, B1
Hedley-Whyte, ET1
Klibanski, A1
Nouman, GS1
Angus, B1
Lunec, J1
Crosier, S1
Lodge, A1
Anderson, JJ1
Armuth, V1
Berenblum, I1
Theiss, JC1
Shimkin, MB1
Lesher, S1
Schiffer, LM1
Phanse, M1
Peter, HJ1
Gerber, H1
Studer, H1
Groscurth, P1
Zakarija, M1
Steenbeck, L1
Jacobasch, KH1
Irro, F1
Brandi, ML1
Aurbach, GD1
Fitzpatrick, LA1
Quarto, R1
Spiegel, AM1
Bliziotes, MM1
Norton, JA1
Doppman, JL1
Marx, SJ1
Müller-Gärtner, HW1
Baisch, H1
Wiegel, T1
Kremer, B1
Schneider, C1
Goretzki, PE2
Koob, R2
Koller, T1
Simon, R1
Branscheid, D1
Clark, OH1
Röher, HD2
West, M1
Koller, C1
Joseph, K1
Kirkhus, B1
Iversen, OH1
Kristensen, A1
Krahenbuhl, JL1
Remington, JS1
Ueno, T1
Shimizu, M1
Sekiyama, S1
Tsou, KC1
Ledis, S1
McCoy, MG1
Jabara, AG2
Wilson, FC1
Fisher, RJ2
Toyne, PH1
Combs, JW1
Purnell, DM1
Kauffman, SL1
Yamashiro, M1
Hershko, A1
Mamont, P1
Shields, R1
Tomkins, GM1
Crocker, TT1
Teeter, A1
Nielsen, B1

Reviews

1 review available for thymidine and Adenoma

ArticleYear
Reliability of rectal epithelial kinetic patterns as an intermediate biomarker of colon cancer.
    Journal of cellular biochemistry. Supplement, 1994, Volume: 19

    Topics: Adenoma; Anticarcinogenic Agents; Autoradiography; Biomarkers, Tumor; Cell Division; Colonic Neoplas

1994

Trials

1 trial available for thymidine and Adenoma

ArticleYear
Validation of proliferation indices as surrogate endpoint biomarkers.
    Journal of cellular biochemistry. Supplement, 1994, Volume: 19

    Topics: Adenoma; Adult; Autoradiography; Biomarkers; Biopsy; Bromodeoxyuridine; Cell Division; Colorectal Ne

1994

Other Studies

32 other studies available for thymidine and Adenoma

ArticleYear
Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study.
    Endocrine-related cancer, 2008, Volume: 15, Issue:2

    Topics: Adenoma; Adult; Aged; Antineoplastic Agents, Hormonal; Cabergoline; Cell Division; Dopamine; Dopamin

2008
Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Oct-15, Volume: 14, Issue:20

    Topics: Adenoma; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cell Proliferation; Colonic Neoplasms; Col

2008
Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours.
    European journal of endocrinology, 2006, Volume: 155, Issue:2

    Topics: Adenoma; Animals; Antineoplastic Agents, Hormonal; Cell Division; Cell Line, Tumor; Cyclin-Dependent

2006
[Cell cycles of cancer cells and chemotherapy--flow cytometric observation of the effects of chemotherapeutic agents on cell kinetics of cultured human lung cancer cells].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1983, Volume: 58, Issue:5

    Topics: Adenoma; Carcinoma; Cells, Cultured; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Flow

1983
Genetic forms of neoplasia in man: a model for the study of tumor promotion in vitro.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Adenoma; Bile Acids and Salts; Cell Adhesion; Cell Cycle; Cell Transformation, Neoplastic; Cell Tran

1982
Effects of gonadal steroids on the growth of human pituitary adenomas in vitro.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1995, Volume: 16, Issue:6

    Topics: Adenoma; Adult; Androgens; Bromocriptine; Cell Division; Dihydrotestosterone; Estradiol; Female; Fol

1995
Effect of lithium on incorporation of bromodeoxyuridine and tritiated thymidine into human parathyroid cells.
    Archives of surgery (Chicago, Ill. : 1960), 1993, Volume: 128, Issue:8

    Topics: Adenoma; Bromodeoxyuridine; Drug Interactions; Humans; Hyperplasia; In Vitro Techniques; Lithium; Pa

1993
Suppression of tyrosine kinase activity inhibits [3H]thymidine uptake in cultured human pituitary tumor cells.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:7

    Topics: Adenoma; Adult; Aged; Animals; Cell Division; Cinnamates; Culture Media, Conditioned; Enzyme Inhibit

1997
Growth and function of human parathyroid tissue transplanted to athymic mice.
    Journal of endocrinological investigation, 1997, Volume: 20, Issue:11

    Topics: Adenoma; Animals; Autoradiography; Biopsy; Humans; Hyperplasia; Male; Mice; Mice, Nude; Parathyroid

1997
Usefulness of markers of cell proliferation in the management of pituitary adenomas.
    Clinical science (London, England : 1979), 1998, Volume: 95, Issue:2

    Topics: Adenoma; Antibodies, Monoclonal; Biomarkers, Tumor; Cell Cycle; Cell Division; Flow Cytometry; Human

1998
Activin effects on neoplastic proliferation of human pituitary tumors.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:3

    Topics: Activin Receptors; Activins; Adenoma; Adult; Aged; Aged, 80 and over; Blotting, Western; Cell Divisi

2000
Comparative assessment expression of the inhibitor of growth 1 gene (ING1) in normal and neoplastic tissues.
    Hybridoma and hybridomics, 2002, Volume: 21, Issue:1

    Topics: Adenoma; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blotting, Western; Breast Neoplasms;

2002
Tritiated thymidine as a broad spectrum initiator in transplacental two-stage carcinogenesis, with phorbol as promoter.
    International journal of cancer, 1979, Sep-15, Volume: 24, Issue:3

    Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male

1979
Inhibiting effect of caffeine on spontaneous and urethan-induced lung tumors in strain A mice.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: Adenoma; Animals; Caffeine; DNA; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experi

1978
Human colonic tumor cell kinetics: potential for therapy.
    Cancer, 1977, Volume: 40, Issue:5 Suppl

    Topics: Adenocarcinoma; Adenoma; Cell Cycle; Cells, Cultured; Colonic Neoplasms; DNA; DNA-Directed DNA Polym

1977
Comparison of FRTL-5 cell growth in vitro with that of xenotransplanted cells and the thyroid of the recipient mouse.
    Endocrinology, 1991, Volume: 128, Issue:1

    Topics: Adenoma; Animals; Cell Division; Cell Line; Clone Cells; DNA Replication; Kinetics; Mice; Mice, Inbr

1991
[Autoradiography of DNA synthesis in colonic mucosa of patients with familial adenomatosis coli].
    Acta histochemica. Supplementband, 1990, Volume: 39

    Topics: Adenoma; Adenomatous Polyposis Coli; Adult; Autoradiography; Colon; DNA Replication; Female; Humans;

1990
Parathyroid mitogenic activity in plasma from patients with familial multiple endocrine neoplasia type 1.
    The New England journal of medicine, 1986, May-15, Volume: 314, Issue:20

    Topics: Adenoma; Adult; Animals; Cattle; Cells, Cultured; Gastrins; Growth Substances; Humans; Hypercalcemia

1986
Increased deoxyribonucleic acid synthesis of autonomously functioning thyroid adenomas: independent of but further stimulable by thyrotropin.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:1

    Topics: Adenoma; Adolescent; Adult; Cytosol; DNA, Neoplasm; Female; Humans; Male; Thymidine; Thymidine Kinas

1989
The effect of thyrotropin and cAMP on DNA synthesis and cell growth of human thyrocytes in monolayer culture.
    Surgery, 1986, Volume: 100, Issue:6

    Topics: Adenoma; Cells, Cultured; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; DNA; Dose-Respon

1986
Adenylate cyclase stimulation and [3H]thymidine incorporation in human thyroid tissues and thyrocyte cultures: the effect of IgG preparation from patients with different thyroid disorders.
    Acta endocrinologica. Supplementum, 1987, Volume: 281

    Topics: Adenoma; Adenylyl Cyclases; Cells, Cultured; DNA Replication; Goiter; Humans; Immunoglobulin G; Thym

1987
Carcinogenic doses of methylnitrosourea induce dose response related delay in transit through S and G2 phases in mouse epidermis: a cell kinetic study.
    Carcinogenesis, 1987, Volume: 8, Issue:3

    Topics: Adenoma; Animals; Carcinoma; DNA Replication; Flow Cytometry; Interphase; Kinetics; Lung Neoplasms;

1987
The role of activated macrophages in specific and nonspecific cytostasis of tumor cells.
    Journal of immunology (Baltimore, Md. : 1950), 1974, Volume: 113, Issue:2

    Topics: Adenoma; Animals; Apicomplexa; Ascitic Fluid; Cell Adhesion; Cell Line; Cells, Cultured; Female; Imm

1974
[Autoradiographic analysis of cell proliferation in normal human oral mucosa and tumor tissue in vitro].
    The Bulletin of Tokyo Medical and Dental University, 1966, Volume: 13, Issue:3

    Topics: Adenocarcinoma; Adenoma; Adult; Ameloblastoma; Autoradiography; Biopsy; Carcinoma, Squamous Cell; Ce

1966
5'-Nucleotide phosphodiesterase isoenzyme pattern in the serum of human hepatoma.
    Cancer research, 1973, Volume: 33, Issue:10

    Topics: Adenoma; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Fetal Proteins; Floxuridine

1973
Effect of early inhibition of DNA synthesis by hydroxyurea on 7,12-dimethylbenz(a)anthracene mammary carcinogenesis in the rat.
    The Journal of pathology, 1974, Volume: 113, Issue:4

    Topics: Adenoma; Animals; Autoradiography; Benz(a)Anthracenes; Carcinoma; Depression, Chemical; DNA; Epithel

1974
An autoradiographic study of the early effects of 7,12-dimethylbenz(a)anthracene and progesterone on DNA synthesis in rat mammary epithelial cells and subsequent tumour development.
    British journal of cancer, 1972, Volume: 26, Issue:4

    Topics: Adenoma; Animals; Autoradiography; Benz(a)Anthracenes; Carcinoma; DNA; Drug Synergism; Epithelial Ce

1972
Functional characteristics of mast cells associated with rat mammary tumors induced by 7,12-dimethylbenz(a)anthracene.
    Journal of the National Cancer Institute, 1973, Volume: 50, Issue:4

    Topics: Adenofibroma; Adenoma; Animals; Autoradiography; Benz(a)Anthracenes; Cell Division; Cystadenoma; End

1973
Alteration in cell proliferation in mouse lung following urethane exposure. II. Effects of chronic exposure on terminal bronchiolar epithelium.
    The American journal of pathology, 1971, Volume: 64, Issue:3

    Topics: Adenoma; Animals; Autoradiography; Bronchi; DNA; Environmental Exposure; Epithelial Cells; Epitheliu

1971
[Organ culture studies of human oral mucous membrane and tumor tissues. 2. Autoradiagraphic studies on the uptake of 3H-thymidine and 3H-uridine].
    Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan, 1968, Volume: 35, Issue:3

    Topics: Adenoma; Adolescent; Adult; Carcinoma, Squamous Cell; Child; Child, Preschool; Culture Techniques; D

1968
"Pleiotypic response".
    Nature: New biology, 1971, Volume: 232, Issue:33

    Topics: Adenoma; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Division; Cell Line; Cell Tran

1971
Postnatal cellular proliferation in mouse and hamster lung.
    Cancer research, 1970, Volume: 30, Issue:2

    Topics: Adenoma; Animals; Animals, Newborn; Autoradiography; Cell Division; Cell Nucleus; Cricetinae; DNA; L

1970