Page last updated: 2024-11-06

thymidine and Acute Kidney Injury

thymidine has been researched along with Acute Kidney Injury in 23 studies

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
" Because previous studies showed that long-term telbivudine treatment improved renal function in chronic hepatitis B virus (HBV) infected patients, we conducted a case-control study to evaluate the clinical outcome of telbivudine preemptive therapy in HBV-related advanced HCC patients treated by combination chemotherapy comprising 5-fluorouracil, mitoxantrone and cisplatin (FMP)."5.19Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study. ( Chang, ML; Chen, YC; Chien, RN; Hsu, CW; Lin, CL; Yeh, C; Yeh, CT, 2014)
"Telbivudine (beta-l-2'-deoxythymidine) is an orally administered nucleoside analog drug approved for the treatment of patients with chronic hepatitis B since 2006."3.77Rhabdomyolysis in a 48-year-old man with hepatitis B-induced cirrhosis. ( Dang, S; Gao, N; Jia, X; Zhang, X, 2011)
"A 54-year-old patient with primary cerebral lymphoma was treated with two 4-weekly cycles of high-dose intravenous cytarabine (12 g/m2) and methotrexate (3 g/m2)."3.71Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure. ( Beijnen, JH; Boogerd, W; Mathĵt, RA; Schellens, JH; Schornagel, JH; Soesan, M; van den Bongard, HJ, 2001)
"After an initial episode of acute tubular necrosis, apparent resistance to gentamicin nephrotoxicity develops in rats during prolonged drug administration."3.67Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function. ( Bennett, WM; Gilbert, DN; Houghton, DC; Lee, D, 1986)
"Glycerol-induced acute renal failure (ARF) inhibited the proliferation of both lipopolysaccharide (LPS)-induced B-lymphocytes and concanavalin A (Con A)-induced T-lymphocytes by 80% and 87%, respectively."1.29Effect of glycerol-induced acute renal failure on glutathione status and mitogen-induced proliferation of rat splenocytes. ( Yeung, JH, 1993)
"Non-oliguric acute renal failure is an increasing disease entity although management of this disease is yet to be established."1.27An autoradiographic analysis of experimental non-oliguric acute renal failure in the mouse. ( Nomoto, H; Nomoto, Y; Sakai, H; Tomino, Y; Watanabe, S, 1985)
"The serum from one patient with acute renal failure suppressed thymidine uptake while her serum obtained after recovery from her illness supported a normal lymphocyte response."1.25Defective cellular immunity in renal failure: depression of reactivity of lymphocytes to phytohemagglutinin by renal failure serum. ( Newberry, WM; Sanford, JP, 1971)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199013 (56.52)18.7374
1990's5 (21.74)18.2507
2000's2 (8.70)29.6817
2010's3 (13.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kader, C1
Sunbul, M1
Das, YK1
Yarim, M1
Bedir, A1
Karaca, E1
Celikbilek, M1
Ozaras, R1
Lin, CL1
Chien, RN1
Yeh, C1
Hsu, CW1
Chang, ML1
Chen, YC1
Yeh, CT1
Dang, S1
Gao, N1
Zhang, X1
Jia, X1
Castro, M1
Cuppage, FE3
Neagoy, DR1
Tate, A3
Vaziri, ND1
Zhou, XJ1
Liao, SY1
Yeung, JH1
Ding, H1
Kopple, JD1
Cohen, A1
Hirschberg, R1
van den Bongard, HJ1
Mathĵt, RA1
Boogerd, W1
Schornagel, JH1
Soesan, M1
Schellens, JH1
Beijnen, JH1
Norman, J1
Tsau, YK1
Bacay, A1
Fine, LG1
Coimbra, TM1
Cieslinski, DA1
Humes, HD1
Nomoto, H1
Watanabe, S1
Tomino, Y1
Nomoto, Y1
Sakai, H1
Houghton, DC1
Lee, D1
Gilbert, DN1
Bennett, WM1
McDermott, FT6
Dalton, MK2
Galbraith, AJ3
Chiga, M1
Castrup, HJ1
Lennartz, KJ1
Nayman, J3
de Boer, WG3
Newberry, WM1
Sanford, JP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Observational, Single-center Post-marketing Surveillance Study of Telbivudine in Chronic Hepatitis B Adults With HBeAg Positive/Negative.[NCT00970216]160 participants (Actual)Observational2009-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

HBV-DNA < 300 Copies/mL in 48 Weeks

(NCT00970216)
Timeframe: 48 weeks

Interventionparticipants (Number)
Chronic Hepatitis B79

Trials

1 trial available for thymidine and Acute Kidney Injury

ArticleYear
Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study.
    Scandinavian journal of gastroenterology, 2014, Volume: 49, Issue:12

    Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc

2014

Other Studies

22 other studies available for thymidine and Acute Kidney Injury

ArticleYear
Telbivudine attenuates gentamicin-induced kidney injury in rats.
    International journal of antimicrobial agents, 2017, Volume: 49, Issue:5

    Topics: Acute Kidney Injury; Animals; Cystatin C; Gentamicins; Glomerular Filtration Rate; Hepatitis B, Chro

2017
Rhabdomyolysis in a 48-year-old man with hepatitis B-induced cirrhosis.
    The American journal of the medical sciences, 2011, Volume: 342, Issue:1

    Topics: Acute Kidney Injury; Antiviral Agents; Fatal Outcome; Fibrosis; Hepatitis B; Humans; Male; Middle Ag

2011
Thymidine rescue: an antidote for pemetrexed-related toxicity in the setting of acute renal failure.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Nov-01, Volume: 21, Issue:21

    Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Cisplatin; Drug Therapy, Combination; Humans;

2003
Repair of the nephron following temporary occlusion of the renal pedicle.
    Laboratory investigation; a journal of technical methods and pathology, 1967, Volume: 17, Issue:6

    Topics: Acute Kidney Injury; Animals; Autoradiography; Basement Membrane; Kidney Function Tests; Kidney Tubu

1967
Erythropoietin enhances recovery from cisplatin-induced acute renal failure.
    The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 2

    Topics: Acute Kidney Injury; Anemia; Animals; Blood Volume; Cisplatin; Erythropoietin; Glomerular Filtration

1994
Effect of glycerol-induced acute renal failure on glutathione status and mitogen-induced proliferation of rat splenocytes.
    Methods and findings in experimental and clinical pharmacology, 1993, Volume: 15, Issue:7

    Topics: Acute Kidney Injury; Animals; B-Lymphocytes; Cells, Cultured; Concanavalin A; DNA; Glutathione; Glut

1993
Recombinant human insulin-like growth factor-I accelerates recovery and reduces catabolism in rats with ischemic acute renal failure.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:5

    Topics: Acute Kidney Injury; Animals; Autoradiography; Blood Urea Nitrogen; Creatinine; DNA; Glomerular Filt

1993
Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure.
    Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:6

    Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Brain Neoplasms; Drug Therapy, Combination; Hu

2001
Epidermal growth factor accelerates functional recovery from ischaemic acute tubular necrosis in the rat: role of the epidermal growth factor receptor.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:5

    Topics: Acute Kidney Injury; Animals; Creatinine; DNA; Epidermal Growth Factor; ErbB Receptors; Kidney; Kidn

1990
Epidermal growth factor accelerates renal repair in mercuric chloride nephrotoxicity.
    The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 2

    Topics: Acute Kidney Injury; Animals; Autoradiography; Blood Urea Nitrogen; Cell Division; Creatinine; Epide

1990
An autoradiographic analysis of experimental non-oliguric acute renal failure in the mouse.
    The Tokai journal of experimental and clinical medicine, 1985, Volume: 10, Issue:5

    Topics: Acute Kidney Injury; Animals; Autoradiography; Carbon Radioisotopes; Male; Mercuric Chloride; Mice;

1985
Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function.
    The American journal of pathology, 1986, Volume: 123, Issue:1

    Topics: Acute Kidney Injury; Autoradiography; Drug Resistance; Gentamicins; Glomerular Filtration Rate; Hist

1986
Repair of the nephron following injury with mercuric chloride.
    The American journal of pathology, 1967, Volume: 51, Issue:3

    Topics: Acid Phosphatase; Acute Kidney Injury; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; His

1967
Ileal epithelial cell migration in acute renal failure. Autoradiographic studies in the mouse.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:12

    Topics: Acute Kidney Injury; Animals; Autoradiography; Cell Migration Inhibition; Cell Survival; Epithelial

1974
Effects of acute renal failure on ileal epithelial cell kinetics: autoradiographic studies in the mouse.
    Gastroenterology, 1974, Volume: 66, Issue:2

    Topics: Acute Kidney Injury; Animals; Autoradiography; Cell Count; Cell Division; DNA; Epithelial Cells; Epi

1974
Cell cycle studies in the regenerating rat nephron following injury with mercuric chloride.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 26, Issue:1

    Topics: Acute Kidney Injury; Animals; DNA; Kidney Tubules; Male; Mercury; Mitosis; Necrosis; Rats; Regenerat

1972
[Change in cell kinetics of gastric surface epithelium in uremia. Autoradiographic study using the percentage of labeled mitoses method].
    Beitrage zur Pathologie, 1972, Volume: 146, Issue:4

    Topics: Acute Kidney Injury; Animals; Autoradiography; Cell Division; Cell Movement; Epithelium; Gastric Muc

1972
Epithelial cell division in acute renal failure: a radio-autographic study in the oesophagus of the mouse.
    The British journal of surgery, 1971, Volume: 58, Issue:1

    Topics: Acute Kidney Injury; Animals; Autoradiography; Cell Division; Epithelium; Esophagus; Gastrointestina

1971
Effect of acute renal failure upon cell division in the jejunum: radioautographic and ultrastructural studies in the mouse.
    Annals of surgery, 1971, Volume: 174, Issue:2

    Topics: Acute Kidney Injury; Animals; Autoradiography; Cell Division; Intestinal Mucosa; Jejunum; Male; Mice

1971
Cell kinetics of the small bowel in acute renal failure.
    The British journal of surgery, 1971, Volume: 58, Issue:4

    Topics: Acute Kidney Injury; Animals; Cell Division; DNA; Epithelium; Intestine, Small; Mice; Thymidine; Tri

1971
Defective cellular immunity in renal failure: depression of reactivity of lymphocytes to phytohemagglutinin by renal failure serum.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:6

    Topics: Acute Kidney Injury; Culture Techniques; Cytotoxicity Tests, Immunologic; Depression, Chemical; DNA;

1971
The effect of acute renal failure upon wound healing: histological and autoradiographic studies in the mouse.
    Annals of surgery, 1968, Volume: 168, Issue:1

    Topics: Acute Kidney Injury; Animals; Injections, Intraperitoneal; Mice; Radiography; Thymidine; Tritium; Ur

1968