Page last updated: 2024-11-06

thymidine and Acrania

thymidine has been researched along with Acrania in 7 studies

Research Excerpts

ExcerptRelevanceReference
"The observation of elevated maternal plasma homocysteine concentration in pregnancies affected by neural tube defects (NTD) suggests that folate metabolism may be disturbed in NTD cases."7.72Homocysteine is embryotoxic but does not cause neural tube defects in mouse embryos. ( Copp, AJ; Dunlevy, LE; Greene, ND, 2003)
" Our aim was to investigate the role of dTMP dysmetabolism via inhibition of TYMS by an inhibitor, 5-fluorouracil (5-FU) in the occurrence of neural tube defects (NTDs)."3.88Inhibition of thymidylate synthase affects neural tube development in mice. ( Dong, Y; Guan, Z; Niu, B; Wang, J; Wang, X; Zhu, Z, 2018)
"The observation of elevated maternal plasma homocysteine concentration in pregnancies affected by neural tube defects (NTD) suggests that folate metabolism may be disturbed in NTD cases."3.72Homocysteine is embryotoxic but does not cause neural tube defects in mouse embryos. ( Copp, AJ; Dunlevy, LE; Greene, ND, 2003)
"Folic acid prevents 70 percent of human neural tube defects (NTDs) but its mode of action is unclear."3.70Embryonic folate metabolism and mouse neural tube defects. ( Copp, AJ; Fleming, A, 1998)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, X1
Guan, Z1
Dong, Y1
Zhu, Z1
Wang, J1
Niu, B1
Leung, KY1
De Castro, SC1
Savery, D1
Copp, AJ3
Greene, ND2
Martiniova, L1
Field, MS1
Finkelstein, JL1
Perry, CA1
Stover, PJ1
Jha, RM1
Liu, X1
Chrenek, R1
Madsen, JR1
Cardozo, DL1
Dunlevy, LE1
Fleming, A1
Bannigan, JG1

Other Studies

7 other studies available for thymidine and Acrania

ArticleYear
Inhibition of thymidylate synthase affects neural tube development in mice.
    Reproductive toxicology (Elmsford, N.Y.), 2018, Volume: 76

    Topics: Animals; Apoptosis; Cell Proliferation; Deoxyuracil Nucleotides; Embryonic Development; Fluorouracil

2018
Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 9

    Topics: Animals; Body Patterning; Cell Proliferation; Disease Models, Animal; Embryo, Mammalian; Female; Fol

2013
Maternal dietary uridine causes, and deoxyuridine prevents, neural tube closure defects in a mouse model of folate-responsive neural tube defects.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:4

    Topics: Animals; Deoxyuridine; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Glycine Hy

2015
The postnatal human filum terminale is a source of autologous multipotent neurospheres capable of generating motor neurons.
    Neurosurgery, 2013, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Animals; Cauda Equina; Cell Differentiation; Cell Separation; Cells, Cultured; Ch

2013
Homocysteine is embryotoxic but does not cause neural tube defects in mouse embryos.
    Anatomy and embryology, 2003, Volume: 206, Issue:3

    Topics: Animals; Central Nervous System; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; F

2003
Embryonic folate metabolism and mouse neural tube defects.
    Science (New York, N.Y.), 1998, Jun-26, Volume: 280, Issue:5372

    Topics: Animals; Central Nervous System; Deoxyuracil Nucleotides; DNA-Binding Proteins; Embryo, Mammalian; F

1998
The effects of 5-bromodeoxyuridine on fusion of the cranial neural folds in the mouse embryo.
    Teratology, 1985, Volume: 32, Issue:2

    Topics: Animals; Body Weight; Bromodeoxyuridine; Dose-Response Relationship, Drug; Embryo, Mammalian; Female

1985