thymidine has been researched along with Abnormalities, Drug-Induced in 39 studies
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disulfiram, in 1 mg and 10 mg oral doses, was given to inbred C3H mice prior to and for the duration of pregnancy." | 3.67 | The effects of disulfiram on the experimental C3H mouse embryo. ( Folb, PI; Thompson, PA, 1985) |
| "Trimethylamine (TMA) is an aliphatic amine, and its blood levels can increase after ingestion of certain foods, such as fish, and during disease states, such as chronic renal failure." | 1.28 | Teratogenic and macromolecular synthesis inhibitory effects of trimethylamine on mouse embryos in culture. ( Guest, I; Varma, DR, 1992) |
| "Hydroxyurea (HU) is a swiftly acting cytotoxic teratogen and an inhibitor of DNA synthesis." | 1.28 | The nature of the embryo-protective interaction of propyl gallate with hydroxyurea. ( DeSesso, JM; Goeringer, GC, 1990) |
| "Hycanthone has been tested for embryotoxic activity in mice and rabbits." | 1.25 | Evaluation of the teratogenic activity of hycanthone in mice and rabbits. ( Adamson, RH; Sieber, SM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (94.87) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BIELIAVSKY, N | 1 |
| CHAUBE, S | 2 |
| MURPHY, ML | 1 |
| Parkash, O | 3 |
| Scott, WJ | 3 |
| Forsthoefel, PF | 1 |
| Williams, ML | 1 |
| Chen, WJ | 1 |
| Body, RL | 1 |
| Mottet, NK | 1 |
| Salzgeber, B | 1 |
| Manson, JM | 1 |
| Dourson, ML | 1 |
| Smith, CC | 1 |
| Sieber, SM | 1 |
| Adamson, RH | 1 |
| Guest, I | 1 |
| Varma, DR | 1 |
| DeSesso, JM | 1 |
| Goeringer, GC | 1 |
| Shah, RM | 1 |
| Chen, YP | 1 |
| Burdett, DN | 1 |
| Runner, MN | 2 |
| Thompson, PA | 1 |
| Folb, PI | 1 |
| Caplan, AI | 2 |
| Katdare, SM | 1 |
| Mulherkar, L | 1 |
| Kury, G | 2 |
| Craig, JM | 1 |
| Williams, JP | 1 |
| Ritter, EJ | 2 |
| Wilson, JG | 3 |
| Seegmiller, RE | 1 |
| Janakidevi, K | 1 |
| Smith, MJ | 1 |
| Daniels, E | 1 |
| Moore, KL | 1 |
| Kotin, AM | 1 |
| Repin, VS | 1 |
| Rizki, RM | 1 |
| Rizki, TM | 1 |
| Wegner, G | 1 |
| Mayer-Rosa, P | 1 |
| Luz, D | 1 |
| Short, RD | 1 |
| Rao, KS | 1 |
| Gibson, JE | 1 |
| Langman, J | 1 |
| Shimada, M | 1 |
| Nanda, R | 1 |
| Hara, H | 1 |
| Rev-Kury, LH | 1 |
| Crosby, RJ | 1 |
| Seifertová, M | 1 |
| Veselý, J | 1 |
| Sorm, F | 1 |
| Kochhar, DM | 1 |
| Jordan, RL | 1 |
| Schumacher, H | 1 |
39 other studies available for thymidine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[EFFECTS OF MITOMYCIN ON THE INCORPORATION OF TRITIATED THYMIDINE INTO AMPHIBIAN EMBRYOS AT THE MORULA STAGE].
Topics: Abnormalities, Drug-Induced; Amphibians; Animals; Cell Division; DNA; Embryo, Mammalian; Embryo, Non | 1963 |
TERATOGENIC EFFECTS OF 5-CHLORODEOXYURIDINE ON THE RAT FETUS; PROTECTION BY PHYSIOLOGICAL PYRIMIDINES.
Topics: Abnormalities, Drug-Induced; Deoxyuridine; Fetus; Pharmacology; Pregnancy; Pregnancy, Animal; Pyrimi | 1964 |
Thymidine teratogenesis and mutagenesis in Drosophila melanogaster.
Topics: Abnormalities, Drug-Induced; Animals; Drosophila; Genes, Lethal; Genes, Recessive; Mutagens; Sex Chr | 1967 |
Pathogenesis of bromodeoxyuridine-induced polydactyly.
Topics: Abnormalities, Drug-Induced; Animals; Bromodeoxyuridine; Cell Survival; Deoxycytidine; DNA; Dose-Res | 1981 |
The effects of 5-fluorouracil and 5-fluorodeoxyuridine used alone and in combination with normal nucleic acid precursors on development of mice in lines selected for low and high expression of Strong's luxoid gene.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cell Survival; Drug Synergism; Female; Fetal Deat | 1975 |
Some effects of continuous low-dose congenital exposure to methylmercury on organ growth in the rat fetus.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cell Division; DNA; Female; Fetal Growth Retardat | 1979 |
[The effect of nitrogen mustard on the incorporation of tritiated thymidine into chick embryo limb buds. Autoradiographic study].
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Chick Embryo; Depression, Chemical; DNA Replicati | 1975 |
Effects of cytosine arabinoside on in vivo and in vitro mouse limb development.
Topics: Abnormalities, Drug-Induced; Animals; Cytarabine; Extremities; Female; Mice; Organ Culture Technique | 1977 |
Evaluation of the teratogenic activity of hycanthone in mice and rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Embryo Implantation; Embryo, Mammalian; Female; Fetal Death; G | 1975 |
Teratogenic and macromolecular synthesis inhibitory effects of trimethylamine on mouse embryos in culture.
Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Culture Techniques; DNA; Embryo, Mammalian; Emb | 1992 |
The nature of the embryo-protective interaction of propyl gallate with hydroxyurea.
Topics: Abnormalities, Drug-Induced; Animals; DNA; Embryo, Mammalian; Female; Hydroxyurea; Injections; Necro | 1990 |
Palatal shelf reorientation in hamster embryos following treatment with 5-fluorouracil.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; DNA; Embryo, Mammalian; Epithelial Cells; Female; | 1989 |
Epigenetically regulated genomic expressions for shortened stature and cleft palate are regionally specific in the 11-day mouse embryo.
Topics: Abnormalities, Drug-Induced; Animals; Cell Cycle; Cell Division; Cleft Palate; Embryo, Mammalian; Et | 1986 |
The effects of disulfiram on the experimental C3H mouse embryo.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Disulfiram; DNA; Embryo, Mammalian; Female; Fetu | 1985 |
Effects of a nicotinamide-sensitive teratogen 6-aminonicotinamide on chick limb cells in culture.
Topics: Abnormalities, Drug-Induced; Amines; Animals; Bone and Bones; Carbon Isotopes; Cartilage; Cells, Cul | 1972 |
Alleviation of the toxicity of actinomycin D by uridine and thymidine on the morphogenesis of chick embryos cultivated in vitro.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Culture Techniques; Dactinomycin; Heart Defects, | 1972 |
Congenital malformations produced in chickens by fluorinated pyrimidines.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Chick Embryo; Floxuridine; Fluorouracil; Pyri | 1966 |
The effects of the nicotinamide sensitive teratogen 3-acetylpyridine on chick limb mesodermal cells in culture: biochemical parameters.
Topics: Abnormalities, Drug-Induced; Animals; Carbon Isotopes; Cartilage; Cell Differentiation; Cells, Cultu | 1972 |
Incorporation of thymidine after administration of fluorouracil and fluorouridine to adult and embryo mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cleft Palate; Dose-Response Relationship, Drug; E | 1971 |
DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytarabine; Depression, Chemical; DNA; Female; F | 1973 |
Normal incorporation rates for precursors of collagen and mucopolysaccharide during expression of micromelia induced by 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Amines; Animals; Carbon Radioisotopes; Chick Embryo; Collagen; Depressi | 1974 |
Effects of salicylate on RNA polymerase activity and on the incorporation of orotic acid and thymidine into the nucleic acids of rat foetuses in vitro.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetus; Nucleic Acids; Orotic Acid; Pregna | 1970 |
Developmental abnormalities in the chicken induced by thymidine and glycine.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Glycine; Growth Disorders; Hot Temperature; Sodi | 1974 |
A direct analysis of early chick embryonic neuroepithelial responses following exposure to EDTA.
Topics: Abnormalities, Drug-Induced; Animals; Cell Aggregation; Cerebral Cortex; Chick Embryo; Culture Media | 1972 |
Protective effects of thymidine, 5-aminoimidazolecarboxamide, and riboflavin against fetal abnormalities produced in rats by 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide.
Topics: Abnormalities, Drug-Induced; Amides; Animals; Brain; Cysteine; Dose-Response Relationship, Drug; Fem | 1973 |
Influence of 2,4-diamino-5-chlorophenyl-6-ethylpyrimidine (chloridyn) on the nucleic acid metabolism of embryos of white rats.
Topics: Abnormalities, Drug-Induced; Animals; Carbon Radioisotopes; DNA; Female; Fetus; Formates; Phosphorus | 1974 |
On the teratogenic effect of thymidine and its suppression by deoxycytidine in Drosophila melanogaster.
Topics: Abnormalities, Drug-Induced; Animals; Cytosine Nucleotides; Depression, Chemical; Drosophila melanog | 1971 |
Morphogenic effects of halogenated thymidine analogs on Drosophila. 3. 5-Iododeoxyuridine.
Topics: Abnormalities, Drug-Induced; Animals; Centrifugation, Density Gradient; Deoxyuridine; DNA; Drosophil | 1972 |
[Hypervitaminosis A in rat embryos. Autoradiographic studies on the teratogenic effect].
Topics: Abnormalities, Drug-Induced; Animals; Autoradiography; DNA; Embryo, Mammalian; Female; Mesencephalon | 1972 |
The in vivo biosynthesis of DNA, RNA, and proteins by mouse embryos after a teratogenic dose of cyclophosphamide.
Topics: Abnormalities, Drug-Induced; Animals; Carbon Isotopes; Cyclophosphamide; DNA; Embryo, Mammalian; Fem | 1972 |
Cerebral cortex of the mouse after prenatal chemical insult.
Topics: Abnormalities, Drug-Induced; Animals; Cerebral Cortex; Chromosome Aberrations; Cytidine; Female; Ges | 1971 |
DNA synthesis inhibition and cell death associated with hydroxyurea teratogenesis in rat embryos.
Topics: Abnormalities, Drug-Induced; Animals; Cell Division; Central Nervous System; DNA; Embryo, Mammalian; | 1971 |
Tritiated thymidine labelling of the palatal processes of rat embryos with cleft palate induced by hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Autoradiography; Cell Nucleus; Cleft Palate; DNA; Embr | 1971 |
[Disturbances of development and differentiation induced in the amphibian embryo by 5-fluorouracil. (Histological and histoautoradiographic examinations)].
Topics: Abnormalities, Drug-Induced; Amphibians; Animals; Anura; Autoradiography; Brain; Cell Nucleus; DNA; | 1970 |
The effect of selenous acid on the hematopoietic system of chicken embryos.
Topics: Abnormalities, Drug-Induced; Anemia; Animals; Autoradiography; Bursa of Fabricius; Chick Embryo; Ery | 1967 |
Effect of 5-azacytidine on developing mouse embryo.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents; Antineoplastic Agents; Autoradiography; | 1968 |
Thymidine-teratogenesis in different species of the genus Drosophila.
Topics: Abnormalities, Drug-Induced; Animals; Drosophila; Species Specificity; Thymidine; Wings, Animal | 1968 |
Studies of vitamin A-induced teratogenesis: effects on embryonic mesenchyme and epithelium, and on incorporation of H3-thymidine.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Cell Division; Cell Membrane Permeabilit | 1968 |
Potentiation of the teratogenic effects of 5-fluorouracil by natural pyrimidines. I. Biological aspects.
Topics: Abnormalities, Drug-Induced; Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Drug Synergis | 1969 |