thymic-factor--circulating and Duodenal-Ulcer

Kept under medical surveillance were 120 patients with duodenal ulcer running an uncomplicated course. All patients and 30 healthy donors were studied for the status of the immunity T-system by spontaneous E-rosette formation (E-RFC) and availability of theophylline-resistant (TPP-RFC) and theophylline-sensitive (TPS-RFC) lymphocytes. With B-system being studied by FAC-rosette formation. All patients with duodenal ulcer displayed a decline in the content of E-RFC, TFP-RFC, TFS-RFC as compared to the indices in controls. Inclusion into the combined therapy of thymalin and dalargin was noted to be associated with a positive dynamics in the rise of T-lymphocytes, their subpopulations to the level in controls, percentage of TFS-RFC. Indices for TFS-RFC did not differ from control ones either before or after the treatment.

Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; B-Lymphocyte Subsets; Chronic Disease; Drug Evaluation; Duodenal Ulcer; Enkephalin, Leucine-2-Alanine; Female; Humans; Male; Middle Aged; T-Lymphocyte Subsets; Thymus Hormones

Topics: Adjuvants, Immunologic; Adolescent; Adult; Duodenal Ulcer; Humans; Immunity, Cellular; Levamisole; Male; T-Lymphocytes; Theophylline; Thymus Hormones

Topics: Adolescent; Adult; B-Lymphocytes; Duodenal Ulcer; Humans; Male; T-Lymphocytes; Thymus Hormones