thymalfasin and Cerebral-Infarction

To evaluate the preventive and therapeutic effect of thymosin alpha(1) on lung infections in critical patients with tracheotomy.. Forty-two patients were randomly divided into treatment group and control group to receive daily subcutaneous thymosin injection at 11.6 mg and saline of 2 ml for 7 days, respectively.. Compared with the control group, the infection rate, white blood cell count, C-reactive protein, tumor necrosis factor-alpha and interleukiu-6 were significantly lower in the treatment group.. Thymosin alpha(1) can be effective for prevention and treatment of lung infections in critical patients with tracheotomy and may improve the patients' immunity and prognosis.

Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Brain Injuries; Cerebral Infarction; Critical Illness; Female; Humans; Intensive Care Units; Male; Middle Aged; Pneumonia; Thymalfasin; Thymosin; Tracheotomy