Page last updated: 2024-09-02

thromboxanes and Endotoxin Shock

thromboxanes has been researched along with Endotoxin Shock in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (86.36)	18.7374
1990's	5 (11.36)	18.2507
2000's	1 (2.27)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fegbeutel, C; Gokorsch, S; Grimminger, F; Hattar, K; Heuer, KU; Krämer, HJ; Mayer, K; Seeger, W; Sibelius, U; Temmesfeld-Wollbrück, B	1
Cook, JA; Halushka, PV; Rambo, W; Reines, HD; Wise, WC	1
Butler, RR; Cook, JA; Halushka, PV; Wise, WC	2
Bottoms, GD; Johnson, MA; Roesel, OF	1
Brackett, DJ; Wilson, MF	1
Carmona, RH; Trunkey, DD; Tsao, TC	1
Furman, BL; McKechnie, K; Parratt, JR	1
Parratt, JR; Sharma, N; Zeitlin, IJ	1
Butler, RR; Cook, JA; Halushka, PV; Rambo, W; Reines, HD; Wise, WC	1
Ditter, H; Matthias, FR	1
Fukumoto, S; Tanaka, K	1
Ikezono, E; Sakanishi, N; Takekawa, K; Tsunoda, Y	1
Cook, JA; Halushka, PV; Tempel, GE; Wise, WC	2
Demling, RH; Flynn, JT	1
Fletcher, JR; Harris, RH; Maddox, Y; Ramwell, PW; Zmudka, M	1
Ishihara, Y; Kitamura, S; Kosaka, K	1
Cook, JA; Halushka, PV; Wise, WC	2
Kakkar, VV; Scully, MF; Webb, PJ; Westwick, J; Zahavi, J	1
Fletcher, JR; Harris, RH; Ramwell, PW	1
Adams, SB; Bottoms, GD; Ewert, KM; Fessler, JF; Johnson, MA; Roesel, OF; Templeton, CB	1
Coppo, PA; Hammerschmidt, DE; Jacob, HS; Xiu, RJ	1
Cook, JA; Halushka, PV; Knapp, DR; Wise, WC	1
Pope, L; Prancan, A; Simon, D	1
Fiscus, RR; Han, C; Jones, SB; Wang, X; Yang, L	1
Blauhut, B; Lundsgaard-Hansen, P	1
Adams, HR; Bottoms, GD	1
Bistrian, BR; Blackburn, GL; Flores, EA; Pomposelli, JJ; Zeisel, SH	1
Esser, KM; Farhat, M; Feuerstein, G; Rabinovici, R; Slivjak, M; Smith, EF; Yue, TL	1
Andreeva, T; Nikolov, N	1
Cook, JA; Halushka, PV; Smith, EF; Strong, JW; Tempel, GE; Wise, WC	1
Pacitti, N; Parratt, JR; Rodger, IW	1
Cook, JA; Halushka, PV; Reines, HD; Tempel, GE; Wise, WC	1
Avrorov, VP; Cherkasova, TD; Dank, EKh; Shepeleva, GK; Vengrov, PR	1
Cumming, AD; Lindsay, RM; Linton, AL; McDonald, JW; Solez, K	1
Ball, HA; Cook, JA; Halushka, PV; Wise, WC	1
Jugus, M; Kinter, LB; Smith, EF	1
Beger, HG; Berger, D; Oettinger, W	1
Casey, LC; Fletcher, JR; Ramwell, PW; Zmudka, MI	1
Glants, RM; Oborin, AN	1
Bowers, GJ; Conklin, JC; Fink, MP; Hirsch, EF; MacVittie, TJ; Nelson, RD; Roethel, RJ	1
Cook, JA; Halushka, PV; Loadholt, CB; Reines, HD	1

Reviews

8 review(s) available for thromboxanes and Endotoxin Shock

Article	Year
Markers and mediators in enterogenic infectious-toxic shock. Current studies in hematology and blood transfusion, 1992, Issue:59 Topics: Animals; Arachidonic Acid; Biomarkers; Endotoxins; Free Radicals; Humans; Hypoxia; Inflammation; Interleukin-1; Intestines; Ischemia; Lymphocyte Activation; Macrophage Activation; Oxygen; Permeability; Prostaglandins; Reperfusion Injury; Risk Factors; Shock, Septic; Thromboxanes; Tumor Necrosis Factor-alpha; Wounds and Injuries	1992
Involvement of prostaglandins and leukotrienes in the pathogenesis of endotoxemia and sepsis. Journal of the American Veterinary Medical Association, 1992, Jun-15, Volume: 200, Issue:12 Topics: Animals; Cyclooxygenase Inhibitors; Leukotriene Antagonists; Leukotrienes; Prostaglandin Antagonists; Prostaglandins; Shock, Septic; Thromboxanes; Toxemia	1992
[Role of vasoactive mediators in endotoxic shock]. Khirurgiia, 1986, Volume: 39, Issue:3 Topics: Animals; Bradykinin; Catecholamines; Endorphins; Histamine; Histamine Release; Kallikreins; Kinins; Prostaglandins; Serotonin; Shock, Septic; Thromboxanes; Vasoactive Intestinal Peptide; Vasopressins	1986
The role of eicosanoids in mediating blood flow alterations in endotoxin shock. Progress in clinical and biological research, 1989, Volume: 299 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Hemodynamics; Humans; Leukotrienes; Lipoxygenase Inhibitors; Rats; Shock, Septic; Thromboxanes	1989
Mediators of acute lung injury in endotoxaemia. Progress in clinical and biological research, 1989, Volume: 308 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cats; Cyclooxygenase Inhibitors; Endotoxins; Escherichia coli; Lung; Lung Diseases; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Shock, Septic; Thromboxane-A Synthase; Thromboxanes	1989
The rat in sepsis and endotoxic shock. Progress in clinical and biological research, 1989, Volume: 299 Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Disease Models, Animal; Humans; Leukotrienes; Prostaglandins; Rats; Shock, Septic; Species Specificity; Thromboxane-A Synthase; Thromboxanes	1989
Role of thromboxane, prostaglandins and leukotrienes in endotoxic and septic shock. Intensive care medicine, 1986, Volume: 12, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Cats; Endotoxins; Fatty Acids, Essential; Hemodynamics; Humans; Leukotriene B4; Prostaglandins; Rats; Shock, Septic; SRS-A; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1986
[Role of prostaglandins in the pathogenesis and treatment of shock]. Klinicheskaia khirurgiia, 1985, Issue:1 Topics: Animals; Dogs; Papio; Prostaglandins; Rats; Sheep; Sheep Diseases; Shock; Shock, Hemorrhagic; Shock, Septic; Thromboxanes	1985

Trials

1 trial(s) available for thromboxanes and Endotoxin Shock

Article	Year
Omega-3 vs. omega-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation. Intensive care medicine, 2003, Volume: 29, Issue:9 Topics: Adult; Aged; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Fish Oils; Humans; Leukotrienes; Male; Middle Aged; Neutrophils; Phosphatidylinositols; Pilot Projects; Platelet Activating Factor; Shock, Septic; Superoxides; Thromboxanes	2003

Article

Year

Omega-3 vs. omega-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation.

Intensive care medicine, 2003, Volume: 29, Issue:9

Topics: Adult; Aged; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Fish Oils; Humans; Leukotrienes; Male; Middle Aged; Neutrophils; Phosphatidylinositols; Pilot Projects; Platelet Activating Factor; Shock, Septic; Superoxides; Thromboxanes

2003

Other Studies

35 other study(ies) available for thromboxanes and Endotoxin Shock

Article	Year
Plasma thromboxane concentrations are raised in patients dying with septic shock. Lancet (London, England), 1982, Jul-24, Volume: 2, Issue:8291 Topics: Arachidonic Acids; Hemodynamics; Humans; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes	1982
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:1 Topics: Animals; Epoprostenol; Fatty Acids, Essential; Female; Fibrin Fibrinogen Degradation Products; Gentamicins; Ibuprofen; Imidazoles; Indomethacin; Macrophages; Male; Peritonitis; Prostaglandins; Prostaglandins F; Rats; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes	1983
Endotoxin-induced hemodynamic changes in dogs: role of thromboxane and prostaglandin I2. American journal of veterinary research, 1983, Volume: 44, Issue:8 Topics: Animals; Clonixin; Dog Diseases; Dogs; Endotoxins; Epoprostenol; Escherichia coli; Female; Hemodynamics; Male; Prostaglandins F; Shock, Septic; Thromboxane B2; Thromboxanes	1983
Release of vasoactive hormones and circulatory changes in shock. Circulatory shock, 1983, Volume: 11, Issue:3 Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Endorphins; Epoprostenol; Hemodynamics; Histamine; Hormones; Humans; Shock, Septic; Thromboxanes; Vasoconstriction; Vasodilation; Vasopressins	1983
The role of prostacyclin and thromboxane in sepsis and septic shock. Archives of surgery (Chicago, Ill. : 1960), 1984, Volume: 119, Issue:2 Topics: Animals; Bacterial Infections; Disease Models, Animal; Epoprostenol; Heart; Hemodynamics; Humans; Hypotension; Myocardial Contraction; Rabbits; Shock, Septic; Thromboxane A2; Thromboxanes	1984
Failure of drugs that selectively inhibit thromboxane synthesis to modify endotoxin shock in conscious rats. British journal of pharmacology, 1984, Volume: 82, Issue:1 Topics: Animals; Blood Glucose; Blood Pressure; Escherichia coli; Heart Rate; Imidazoles; Lactates; Lactic Acid; Male; Platelet Count; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2; Thromboxanes	1984
Prostaglandins and thromboxane in the delayed phase of shock induced by Serratia marcescens endotoxin. British journal of pharmacology, 1984, Volume: 82, Issue:1 Topics: Animals; Arachidonic Acids; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Cardiac Output; Cats; Endotoxins; Female; Hemodynamics; Hydrogen-Ion Concentration; Male; Oxygen; Prostaglandins; Serratia marcescens; Shock, Septic; Thromboxanes	1984
The potential role of thromboxane and prostacyclin in endotoxic and septic shock. The American journal of emergency medicine, 1984, Volume: 2, Issue:1 Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Fatty Acids; Gentamicins; Ibuprofen; Imidazoles; Methacrylates; Peritonitis; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane-A Synthase; Thromboxanes	1984
Changes in thromboxane formation by platelets during and after a continuous endotoxin infusion into rabbits. VASA. Zeitschrift fur Gefasskrankheiten, 1984, Volume: 13, Issue:4 Topics: Animals; Blood Platelets; Female; Male; Platelet Aggregation; Rabbits; Shock, Septic; Thromboxane B2; Thromboxanes	1984
Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. Prostaglandins, leukotrienes, and medicine, 1983, Volume: 11, Issue:2 Topics: Animals; Fibrinogen; Glucuronidase; Kidney; Male; Methacrylates; Oxidoreductases; Platelet Count; Rats; Rats, Inbred Strains; Shock, Septic; Thrombosis; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1983
Thromboxane A2 and hemodynamic-biochemical parameters in canine endotoxin shock. The Bulletin of Tokyo Medical and Dental University, 1983, Volume: 30, Issue:2 Topics: Animals; Blood Pressure; Dogs; Glucuronidase; Glutathione; Heart Rate; Lactates; Lactic Acid; Radioimmunoassay; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes; Vascular Resistance	1983
Thromboxane and prostacyclin production during septic shock. Advances in shock research, 1982, Volume: 7 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Epoprostenol; Fatty Acids, Essential; Female; Fibrin Fibrinogen Degradation Products; Indomethacin; Peritonitis; Prostaglandins; Rats; Rats, Inbred Strains; Shock, Septic; Thrombocytopenia; Thromboxane A2; Thromboxanes; Time Factors	1982
The improvement in endotoxin-induced redistribution of organ blood flow by inhibition of thromboxane and prostaglandin synthesis. Advances in shock research, 1982, Volume: 7 Topics: Animals; Arachidonic Acids; Blood Circulation; Cardiac Output; Cerebrovascular Circulation; Coronary Circulation; Endotoxins; Fatty Acids, Essential; Hemodynamics; Indomethacin; Male; Microspheres; Pulmonary Circulation; Rats; Rats, Inbred Strains; Salmonella enteritidis; Shock, Septic; Strontium Radioisotopes; Thromboxanes	1982
Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. Advances in shock research, 1982, Volume: 7 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cardiac Output; Endotoxins; Epoprostenol; Escherichia coli; Leukocyte Count; Platelet Count; Prostaglandins; Pulmonary Artery; Sheep; Shock, Septic; Thromboxane B2; Thromboxanes; Vascular Resistance	1982
Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. Advances in prostaglandin and thromboxane research, 1980, Volume: 7 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arteries; Blood Pressure; Haplorhini; Indomethacin; Lidocaine; Papio; Prostaglandins F; Shock, Septic; Thromboxane B2; Thromboxanes	1980
[Experimental investigation on the pathogenesis of endotoxin shock--the change of plasma serotonin, histamine, thromboxane B2 and 6-keto PGF1 alpha levels and modulation by indomethacin (author's transl)]. Nihon Kyobu Shikkan Gakkai zasshi, 1982, Volume: 20, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dogs; Histamine; Indomethacin; Serotonin; Shock, Septic; Thromboxane A2; Thromboxanes	1982
Implications for thromboxane A2 in the pathogenesis of endotoxic shock. Advances in shock research, 1981, Volume: 6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Disseminated Intravascular Coagulation; Fibrin Fibrinogen Degradation Products; Ibuprofen; Indomethacin; Male; Muridae; Prostaglandins E; Prostaglandins F; Shock, Septic; Thromboxane A2; Thromboxanes	1981
Do prostacyclin and thromboxane play a role in endotoxic shock? The British journal of surgery, 1981, Volume: 68, Issue:10 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Blood Pressure; Epoprostenol; Kallikreins; Leukocyte Count; Platelet Count; Rabbits; Shock, Septic; Swine; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1981
Thromboxane, prostacyclin, and hemodynamic events in primate endotoxin shock. Advances in shock research, 1981, Volume: 5 Topics: Animals; Blood Pressure; Epoprostenol; Hemodynamics; Male; Papio; Prostaglandins; Shock, Septic; Thromboxanes	1981
Thromboxane, prostaglandin I2 (epoprostenol), and the hemodynamic changes in equine endotoxin shock. American journal of veterinary research, 1982, Volume: 43, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Epoprostenol; Escherichia coli; Female; Hemodynamics; Horse Diseases; Horses; Male; Primates; Prostaglandin Antagonists; Prostaglandins; Rabbits; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes	1982
Anisodamine inhibits thromboxane synthesis, granulocyte aggregation, and platelet aggregation. A possible mechanism for its efficacy in bacteremic shock. JAMA, 1982, Mar-12, Volume: 247, Issue:10 Topics: Animals; Cell Aggregation; Cricetinae; Depression, Chemical; Granulocytes; Humans; Ibuprofen; Platelet Aggregation; Scopolamine Derivatives; Shock, Septic; Solanaceous Alkaloids; Structure-Activity Relationship; Thromboxane B2; Thromboxanes; Vasodilator Agents	1982
Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2. Circulatory shock, 1981, Volume: 8, Issue:1 Topics: Animals; Arachidonic Acids; Endotoxins; Fatty Acids, Essential; Fibrin Fibrinogen Degradation Products; Platelet Count; Rats; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes	1981
Platelet thromboxane production during endotoxin shock. Agents and actions, 1981, Volume: 11, Issue:6-7 Topics: Animals; Blood Platelets; Male; Platelet Count; Rabbits; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes; Time Factors	1981
Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency. The Journal of clinical investigation, 1980, Volume: 65, Issue:1 Topics: Animals; Fatty Acids, Essential; Imidazoles; Prostanoic Acids; Rats; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes	1980
Calcitonin gene-related peptide release in endotoxicosis may be mediated by prostaglandins. Shock (Augusta, Ga.), 1995, Volume: 3, Issue:1 Topics: Animals; Aspirin; Blood Glucose; Blood Pressure; Calcitonin Gene-Related Peptide; Cyclooxygenase Inhibitors; Drug Tolerance; Ibuprofen; Imidazoles; Indomethacin; Lactates; Lipopolysaccharides; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Rats, Wistar; Shock, Septic; Thromboxanes	1995
Diets enriched with N-3 fatty acids ameliorate lactic acidosis by improving endotoxin-induced tissue hypoperfusion in guinea pigs. Annals of surgery, 1991, Volume: 213, Issue:2 Topics: Acidosis, Lactic; Animals; Dietary Fats; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Fish Oils; Guinea Pigs; Hemodynamics; Indomethacin; Lung; Male; Muscles; Phenylacetates; Regional Blood Flow; Safflower Oil; Shock, Septic; Skin; Sulfonamides; Thromboxanes	1991
Platelet activating factor (PAF) and tumor necrosis factor-alpha (TNF alpha) interactions in endotoxemic shock: studies with BN 50739, a novel PAF antagonist. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:1 Topics: Animals; Azepines; Blood Cells; Hemodynamics; Humans; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Recombinant Proteins; Shock, Septic; Thromboxanes; Triazoles; Tumor Necrosis Factor-alpha	1990
[Prostaglandins and cyclic nucleotides in the dynamic development of an experimental poisoning syndrome caused by Yersinia pestis lipopolysaccharide]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1989, Issue:1 Topics: Animals; Guinea Pigs; Lipopolysaccharides; Liver; Lung; Nucleotides, Cyclic; Prostaglandins; Shock, Septic; Syndrome; Thromboxanes; Yersinia pestis	1989
The protective effect of thromboxane synthetase inhibition on renal function in systemic sepsis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 13, Issue:2 Topics: Animals; Benzofurans; Glomerular Filtration Rate; Kidney; Natriuresis; Peritonitis; Sheep; Shock, Septic; Thromboxane-A Synthase; Thromboxanes	1989
Effect of the thromboxane receptor antagonist, BM 13.505, on the sequelae of endotoxemia in the conscious rat. Eicosanoids, 1988, Volume: 1, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Pressure; Endotoxins; Heart Rate; Leukocyte Count; Male; Phenylacetates; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Salmonella enteritidis; Shock, Septic; Sulfonamides; Thromboxanes	1988
The clinical significance of prostaglandins and thromboxane as mediators of septic shock. Klinische Wochenschrift, 1987, Jan-15, Volume: 65, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Adolescent; Adult; Aged; Dinoprost; Endotoxins; Epoprostenol; Humans; Middle Aged; Peritonitis; Prostaglandins; Prostaglandins F; Respiratory Insufficiency; Shock, Septic; Surgical Wound Infection; Thromboxanes	1987
The role of thromboxane in primate endotoxin shock. The Journal of surgical research, 1985, Volume: 39, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Hemodynamics; Imidazoles; Leukocyte Count; Male; Methacrylates; Papio; Random Allocation; Shock, Septic; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Time Factors	1985
Prostanoid production by lipopolysaccharide-stimulated Kupffer cells. The Journal of surgical research, 1985, Volume: 38, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Escherichia coli; Kupffer Cells; Male; Polysaccharides, Bacterial; Prostaglandins E; Radioimmunoassay; Rats; Rats, Inbred Strains; Shock, Septic; Stimulation, Chemical; Thromboxane A2; Thromboxane B2; Thromboxanes	1985
Exchange transfusions in rats with a perfluorated blood substitute: effect on thromboxane B2 levels during endotoxemia. Circulatory shock, 1985, Volume: 15, Issue:3 Topics: Animals; Blood Substitutes; Exchange Transfusion, Whole Blood; Fluorocarbons; Leukocyte Count; Male; Platelet Count; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2; Thromboxanes	1985
Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock. Surgery, gynecology & obstetrics, 1985, Volume: 160, Issue:4 Topics: Aspirin; Blood Coagulation; Glucocorticoids; Humans; Methylprednisolone; Oxygen; Oxygen Consumption; Radioimmunoassay; Shock, Septic; Thromboxane B2; Thromboxanes	1985