thromboxane-a2 and Xeroderma-Pigmentosum

thromboxane-a2 has been researched along with Xeroderma-Pigmentosum* in 1 studies

Other Studies

1 other study(ies) available for thromboxane-a2 and Xeroderma-Pigmentosum

Article	Year
A defect in thromboxane A2 synthesis may be a factor predisposing to cancer. Prostaglandins and medicine, 1978, Volume: 1, Issue:2 A failure of thromboxane (TX) A2 synthesis may be a factor in cancer. Such a loss could explain the susceptibility to mutation, the excess prostaglandin production, the glycolytic mode of metabolism and the deranged calcium pumping characteristic of cancers. Ionising radiation and phorbols both have actions similar to inhibitors of TXA2 synthesis whereas colchicine and oxygen have actions consistent with stimulation of TXA2 synthesis. The concept accounts logically for hitherto unexplained features of cancer and suggests new strategies for the prevention and treatment of cancer. Topics: Animals; DNA; Humans; Mutation; Neoplasms; Prostaglandins; Psoriasis; Radiation Injuries; Thromboxane A2; Thromboxanes; Ultraviolet Rays; Xeroderma Pigmentosum	1978

Article

Year

A defect in thromboxane A2 synthesis may be a factor predisposing to cancer.

Prostaglandins and medicine, 1978, Volume: 1, Issue:2

A failure of thromboxane (TX) A2 synthesis may be a factor in cancer. Such a loss could explain the susceptibility to mutation, the excess prostaglandin production, the glycolytic mode of metabolism and the deranged calcium pumping characteristic of cancers. Ionising radiation and phorbols both have actions similar to inhibitors of TXA2 synthesis whereas colchicine and oxygen have actions consistent with stimulation of TXA2 synthesis. The concept accounts logically for hitherto unexplained features of cancer and suggests new strategies for the prevention and treatment of cancer.

Topics: Animals; DNA; Humans; Mutation; Neoplasms; Prostaglandins; Psoriasis; Radiation Injuries; Thromboxane A2; Thromboxanes; Ultraviolet Rays; Xeroderma Pigmentosum

1978