thromboxane-a2 has been researched along with Fecal-Incontinence* in 1 studies
1 other study(ies) available for thromboxane-a2 and Fecal-Incontinence
Article | Year |
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Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
Aging-associated decrease in internal anal sphincter (IAS) tone (AADI) is a major contributor in the rectoanal incontinence (RI). To determine the pathogenesis of AADI, we investigated the effect of aging on GPCR activation and related downstream signaling. We particularly investigated two GPCRs that characterize IAS smooth muscle cells (SMCs): thromboxane A Topics: Aging; Anal Canal; Animals; Fecal Incontinence; Incidence; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Pennsylvania; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Rectum; Thromboxane A2 | 2019 |