thromboxane-a2 and Familial-Mediterranean-Fever

thromboxane-a2 has been researched along with Familial-Mediterranean-Fever* in 1 studies

Other Studies

1 other study(ies) available for thromboxane-a2 and Familial-Mediterranean-Fever

Article	Year
The effect of long-term colchicine therapy in patients with recurrent polyserositis on the capacity of blood platelets to synthesize thromboxane A2. British journal of clinical pharmacology, 1983, Volume: 16, Issue:2 Thromboxane B2 (TXB) production during platelet activation was measured in 13 patients with recurrent polyserositis on long-term colchicine therapy and 10 healthy controls. Plasma colchicine concentration in patients ranged between 0.8-7.8 ng/ml (2.0-19.5 X 10(-9) M). Thromboxane production induced during aggregation by arachidonic acid or collagen and serum TXB2 levels (clotted blood, 37 degrees C, 1 h) did not differ among patients and controls. Previous studies reporting platelet function defects including anomalous TXB2 production, were performed in vitro using colchicine concentrations markedly exceeding the therapeutic range. Topics: Adolescent; Adult; Blood Cell Count; Blood Platelets; Colchicine; Familial Mediterranean Fever; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxanes	1983

Article

Year

The effect of long-term colchicine therapy in patients with recurrent polyserositis on the capacity of blood platelets to synthesize thromboxane A2.

British journal of clinical pharmacology, 1983, Volume: 16, Issue:2

Thromboxane B2 (TXB) production during platelet activation was measured in 13 patients with recurrent polyserositis on long-term colchicine therapy and 10 healthy controls. Plasma colchicine concentration in patients ranged between 0.8-7.8 ng/ml (2.0-19.5 X 10(-9) M). Thromboxane production induced during aggregation by arachidonic acid or collagen and serum TXB2 levels (clotted blood, 37 degrees C, 1 h) did not differ among patients and controls. Previous studies reporting platelet function defects including anomalous TXB2 production, were performed in vitro using colchicine concentrations markedly exceeding the therapeutic range.

Topics: Adolescent; Adult; Blood Cell Count; Blood Platelets; Colchicine; Familial Mediterranean Fever; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxanes

1983