thromboplastin has been researched along with Gastrointestinal-Hemorrhage* in 14 studies
3 review(s) available for thromboplastin and Gastrointestinal-Hemorrhage
Article | Year |
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Organ-specific bleeding patterns of anticoagulant therapy: lessons from clinical trials.
Anticoagulants are effective at preventing and treating thrombosis, but can cause bleeding. For decades, vitamin K antagonists (VKAs) have been the only available oral anticoagulants. The development of non-VKA oral anticoagulants (NOACs), which inhibit either factor Xa or thrombin stoichiometrically, has provided alternatives to VKAs for several indications. The results of recent large-scale randomised controlled trials comparing NOACs with VKAs for the prevention of stroke in patients with non-valvular atrial fibrillation (AF) have produced some unexpected results. As a group, NOACs showed similar efficacy as warfarin, but a reduced risk of major bleeding. The reduction in bleeding with NOACs was greatest with intracranial hemorrhage. In contrast, the relative risk of gastro-intestinal bleeding was increased with some NOACs. In this review, we explore the potential mechanisms as well as the implications of these organ-specific bleeding patterns. Topics: Anticoagulants; Atrial Fibrillation; Blood Coagulation Factors; Endothelium, Vascular; Factor Xa Inhibitors; Gastrointestinal Hemorrhage; Hemorrhage; Humans; International Normalized Ratio; Intestinal Absorption; Intracranial Hemorrhages; Organ Specificity; Randomized Controlled Trials as Topic; Stroke; Thrombophilia; Thromboplastin; Vitamin K; Warfarin | 2014 |
Parahemophilia. Factor V deficiency.
Topics: Adult; Child; Ecchymosis; Epistaxis; Factor V; Factor V Deficiency; Female; Gastrointestinal Hemorrhage; Hemarthrosis; Hematuria; Hemorrhage; Humans; Hypoprothrombinemias; Male; Menstruation Disturbances; Prothrombin Time; Thromboplastin | 1972 |
The management of bleeding in hemophilia.
Topics: Blood Coagulation Factors; Blood Coagulation Tests; Blood Transfusion; Cerebral Hemorrhage; Epistaxis; Factor VIII; Gastrointestinal Hemorrhage; Hemarthrosis; Hematuria; Hemophilia A; Hemorrhage; Humans; Oral Hemorrhage; Thromboplastin; Wounds and Injuries | 1969 |
11 other study(ies) available for thromboplastin and Gastrointestinal-Hemorrhage
Article | Year |
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Coeliac disease presenting as variceal haemorrhage.
Topics: Anticoagulants; Celiac Disease; Diagnosis, Differential; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Mesenteric Vascular Occlusion; Mesenteric Veins; Middle Aged; Thromboplastin; Thrombosis; Vitamin K | 2003 |
The effect of pH on platelet and coagulation factor activities.
After observing that lavage of the stomach with alkaline solutions has a beneficial effect on the control of gastric hemorrhage, we examined the platelet and coagulation factor activities under conditions of lower and elevated pH. The results showed that change of the pH from acidosis to 7.0 and even to slight alkalosis induces platelet aggregation, platelet calcium and serotonin release, as well as platelet factor II availability. The prothrombin and partial thromboplastin times approached normal levels, whereas the fibrinogen level did not change significantly. The results obtained may serve as an explanation for the control of the intragastric bleeding in patients treated by maintenance of their gastric pH at 7.0. Topics: Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelets; Calcium; Epinephrine; Gastrointestinal Hemorrhage; Humans; Hydrogen-Ion Concentration; Platelet Aggregation; Serotonin; Thromboplastin | 1978 |
Prevention of thromboplastin-induced intravascular coagulation in rabbits by warfarin as monitored by thrombotest.
Topics: Animals; Blood Coagulation; Blood Platelets; Depression, Chemical; Disseminated Intravascular Coagulation; Ethanol; Factor V; Female; Fibrinogen; Gastrointestinal Hemorrhage; Hematocrit; Infusions, Parenteral; Male; Rabbits; Thromboplastin; Time Factors; Warfarin | 1974 |
Chronic intravascular coagulation in metastatic prostate cancer.
Topics: Aged; Blood Coagulation Tests; Blood Platelet Disorders; Chronic Disease; Disseminated Intravascular Coagulation; Fibrin; Gastrointestinal Hemorrhage; Heparin; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Prothrombin Time; Thromboplastin | 1973 |
[Conservative treatment of intestinal hemorrhage].
Topics: Adult; Aged; Antifibrinolytic Agents; Blood Transfusion; Dextrans; Female; Gastrointestinal Hemorrhage; Humans; Infusions, Parenteral; Male; Middle Aged; Thromboplastin | 1971 |
Hyperfibrinolysis in cirrhosis.
Topics: Fibrinolysis; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Prothrombin Time; Serum Globulins; Thromboplastin | 1970 |
Coagulation abnormalities in cystic fibrosis.
Topics: Anti-Bacterial Agents; Blood Cell Count; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Platelets; Child; Cystic Fibrosis; Fibrinolysis; Gastrointestinal Hemorrhage; Hemoptysis; Hepatomegaly; Humans; Liver; Liver Function Tests; Lung; Prospective Studies; Prothrombin Time; Splenomegaly; Thrombocytopenia; Thromboplastin; Vitamin K | 1970 |
Serum transfusion as a hemostatic procedure.
Topics: ABO Blood-Group System; Adolescent; Adult; Aged; Anemia, Aplastic; Blood Coagulation; Blood Coagulation Tests; Blood Transfusion; Capillary Fragility; Centrifugation; Female; Fibrinolysin; Fibrinolysis; Gastrointestinal Hemorrhage; Hematuria; Hemostasis; Hepatitis; Humans; Leukemia, Myeloid; Male; Middle Aged; Prothrombin Time; Stomach Neoplasms; Stomach Ulcer; Thrombin; Thromboangiitis Obliterans; Thromboplastin | 1969 |
Von Willebrand's disease in two families. Case reports with a contribution to the management of chronic intestinal hemorrhages.
Topics: Blood Coagulation Tests; Blood Platelet Disorders; Blood Transfusion; Factor VIII; Gastrointestinal Hemorrhage; Hemophilia A; Humans; Male; Thromboplastin; von Willebrand Diseases | 1965 |
Plasma thromboplastin antecedent deficiency. Report of a case and review of literature.
Topics: Blood Coagulation Disorders; Factor XI Deficiency; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Thromboplastin | 1962 |
Massive gastroduodenal hemorrhage: treatment with powdered gelfoam and buffered thrombin solution; a preliminary report.
Topics: Duodenum; Gastrointestinal Hemorrhage; Gelatin Sponge, Absorbable; Hemorrhage; Humans; Stomach; Thrombin; Thromboplastin | 1952 |