threonine has been researched along with Multiple Myeloma in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, ZZ; Huang, QL; Jiang, RY; Wu, DP; Wu, XJ; Yan, S; Yang, BY; Yang, LL; Zhao, RR | 1 |
| Cornish Carmony, K; Kim, KB; Lee, DM; Lee, W; Park, JE; Sharma, LK | 1 |
| Kłoczko, J; Ołdziej, AE; Romaniuk, W; Zińczuk, J | 1 |
| Bocchia, M; Brambilla, CZ; Candi, V; Gozzetti, A; Papini, G; Sirianni, S | 1 |
| Berenson, JR; Bonavida, B; Chen, H; Li, M; Li, ZW; Sanchez, E; Shen, J; Steinberg, JA; Wang, C | 1 |
| Bagnati, R; Cereda, R; D'Incalci, M; Livi, V; Marangon, E; Sala, F; Zucchetti, M | 1 |
| Appel, A | 1 |
| Gallastegui, N; Groll, M | 1 |
| Berenson, JR; Chen, H; Hunter, K; Jones-Bolin, S; Li, J; Li, M; Ruggeri, B; Sanchez, E; Wang, C | 1 |
| Böhm, S; Brunelli, D; Cereda, R; D'Incalci, M; De Braud, F; Delmonte, A; Driessen, C; Gallerani, E; Hess, D; Marangon, E; Marsoni, S; Martinelli, G; Noberasco, C; Sala, F; Sessa, C; Zucchetti, M | 1 |
| Allievi, C; Berkers, C; Bernareggi, A; Bussolati, B; Camussi, G; Cassin, M; Coscia, M; Costa, G; de Feudis, P; di Giovine, S; Ferracini, R; Ferrero, D; Giai, V; Hunter, K; Inghirami, G; Jones-Bolin, S; Massaia, M; Neri, A; Nicoli, P; Ovaa, H; Palumbo, A; Peola, S; Pescalli, N; Pezzoni, G; Piva, R; Roato, I; Ruggeri, B; Strepponi, I; Tamagno, I; Williams, M; Zhao, H | 1 |
| Clement, C; de Hon, FD; Ehlers, M; Herrman, J; Kishimoto, T; Ohsugi, Y; Rose-John, S; Taga, T; ten Boekel, E; Yasukawa, K | 1 |
| Ackermann, A; Baumal, R; Wilson, B | 1 |
| Coffino, P; Knowles, B; Nathenson, SG; Scharff, MD | 1 |
| Clamp, JR; Dawson, G | 1 |
| Buxbaum, J; Scharff, MD | 1 |
| Bargellesi, A; Periman, P; Scharff, MD | 1 |
| Lanzerotti, R; Laskov, R; Scharff, MD | 1 |
| Baumal, R; Potter, M; Scharff, MD | 1 |
| Buxbaum, J; Franklin, EC; Scharff, MD; Zolla, S | 1 |
3 review(s) available for threonine and Multiple Myeloma
| Article | Year |
|---|---|
[Proteasome inhibitors in cancer therapy].
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspases; Dipeptides; Humans; Lactones; Multiple Myeloma; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Pyrroles; Thiazoles; Threonine | 2015 |
Second Generation Proteasome Inhibitors in Multiple Myeloma.
Topics: Animals; Boronic Acids; Bortezomib; Central Nervous System Neoplasms; Drug Discovery; Humans; Lactones; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Proteasome Inhibitors; Pyrroles; Threonine | 2017 |
A first in human phase I study of the proteasome inhibitor CEP-18770 in patients with advanced solid tumours and multiple myeloma.
Topics: Adult; Aged; Boronic Acids; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasms; Proteasome Inhibitors; Threonine | 2013 |
1 trial(s) available for threonine and Multiple Myeloma
| Article | Year |
|---|---|
A first in human phase I study of the proteasome inhibitor CEP-18770 in patients with advanced solid tumours and multiple myeloma.
Topics: Adult; Aged; Boronic Acids; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasms; Proteasome Inhibitors; Threonine | 2013 |
17 other study(ies) available for threonine and Multiple Myeloma
| Article | Year |
|---|---|
[Preliminary exploration of the metabolic profile and metabolic pathways in newly diagnosed multiple myeloma].
Topics: Adult; Aged; Biomarkers; Cysteine; Female; Humans; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Methionine; Middle Aged; Multiple Myeloma; Phenylalanine; Reproducibility of Results; Serine; Threonine | 2022 |
Elucidating the catalytic subunit composition of distinct proteasome subtypes: a crosslinking approach employing bifunctional activity-based probes.
Topics: Catalytic Domain; Cell Line, Tumor; Cross-Linking Reagents; Humans; Inhibitory Concentration 50; Molecular Probe Techniques; Molecular Probes; Multiple Myeloma; Polyethylene Glycols; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Threonine | 2015 |
The proteasome inhibitor CEP-18770 enhances the anti-myeloma activity of bortezomib and melphalan.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Death; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Male; Melphalan; Mice; Mice, SCID; Multiple Myeloma; Proteasome Inhibitors; Pyrazines; Threonine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2010 |
Development and validation of a high-performance liquid chromatography-tandem mass spectrometry method for the determination of the novel proteasome inhibitor CEP-18770 in human plasma and its application in a clinical pharmacokinetic study.
Topics: Acetonitriles; Biphenyl Compounds; Boronic Acids; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Drug Stability; Humans; Irbesartan; Multiple Myeloma; Neoplasms; Proteasome Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tetrazoles; Threonine | 2010 |
Drugs: More shots on target.
Topics: Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Clinical Trials as Topic; Drug Resistance, Neoplasm; Glycine; Humans; Immunologic Factors; Lenalidomide; Multiple Myeloma; Oligopeptides; Protease Inhibitors; Pyrazines; Survival Rate; Thalidomide; Threonine | 2011 |
Analysing properties of proteasome inhibitors using kinetic and X-ray crystallographic studies.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Lactones; Multiple Myeloma; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Saccharomyces cerevisiae; Threonine | 2012 |
CEP-18770 (delanzomib) in combination with dexamethasone and lenalidomide inhibits the growth of multiple myeloma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Cell Line, Tumor; Dexamethasone; Humans; Lenalidomide; Mice; Mice, SCID; Multiple Myeloma; Thalidomide; Threonine; Xenograft Model Antitumor Assays | 2012 |
CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Inhibitors; Humans; Macrophage Colony-Stimulating Factor; Mice; Mice, Nude; Multiple Myeloma; Neoplasms; NF-kappa B; Osteogenesis; Proteasome Inhibitors; Pyrazines; RANK Ligand; Threonine; Treatment Outcome; Ubiquitin; Xenograft Model Antitumor Assays | 2008 |
Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130.
Topics: Alanine; Antibodies, Monoclonal; Antigens, CD; Gene Library; Genetic Testing; Glutamine; Histidine; Humans; Interleukin-6; Multiple Myeloma; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptors, Interleukin; Receptors, Interleukin-6; Signal Transduction; Threonine; Tumor Cells, Cultured | 1995 |
Immunoglobulin biosynthesis in myeloma-associated and casein- and endotoxin-induced murine amyloidosis.
Topics: Amyloid; Amyloidosis; Animals; Carbon Radioisotopes; Caseins; Endotoxins; Fluorescent Antibody Technique; Immune Sera; Immunoglobulins; Kidney; Leucine; Lipopolysaccharides; Liver; Lung; Lymphocytes; Mice; Mice, Inbred Strains; Multiple Myeloma; Myocardium; Plasma Cells; Salmonella typhi; Spleen; Threonine; Tritium; Valine | 1975 |
Suppression of immunoglobulin synthesis by cellular hybridization.
Topics: Animals; Carbon Isotopes; Cell Fusion; Cell Line; Cytogenetics; Fibroblasts; gamma-Globulins; Hybridization, Genetic; Immunoglobulins; In Vitro Techniques; Leucine; Mice; Multiple Myeloma; Peptide Biosynthesis; Threonine; Tritium; Valine | 1971 |
The presence of two types of carbohydrate-amino acid linkage in the same glycoprotein.
Topics: Aspartic Acid; Chromatography, Paper; Galactose; gamma-Globulins; Glycoproteins; Hexoses; Mannose; Multiple Myeloma; Neuraminic Acids; Peptides; Serine; Threonine | 1967 |
The synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. VI. Assembly of IgM proteins.
Topics: Animals; Carbon Isotopes; Culture Media; Electrophoresis, Polyacrylamide Gel; Immune Sera; Immunoglobulin Fragments; Immunoglobulin M; Leucine; Methods; Mice; Mice, Inbred BALB C; Molecular Weight; Multiple Myeloma; Neoplasm Transplantation; Threonine; Transplantation, Homologous; Valine | 1973 |
Synthesis, assembly, and secretion of globulin by mouse myeloma cells. IV. Assembly of IgA.
Topics: Animals; Carbon Isotopes; Cell Line; Immunoglobulin A; Immunoglobulins; Leucine; Mice; Multiple Myeloma; Myeloma Proteins; Neoplasms, Experimental; Rabbits; Sheep; Threonine; Valine | 1972 |
Synthesis, assembly and secretion of gamma globulin by mouse myeloma cells. II. Assembly of IgG2b immunoglobulin by MPC 11 tumor and culture cells.
Topics: Animals; Carbon Isotopes; Chromatography, DEAE-Cellulose; Culture Techniques; Cycloheximide; Cytoplasm; Electrophoresis; Immunoglobulin G; Immunoglobulins; Leucine; Mice; Molecular Weight; Multiple Myeloma; Neoplasms, Experimental; Threonine; Valine | 1971 |
Synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. 3. Assembly of the three subclasses of IgG.
Topics: Animals; Antibody Formation; Carbon Isotopes; Cell Line; Immunoglobulin G; Immunoglobulins; Kinetics; Leucine; Lymph Nodes; Mice; Multiple Myeloma; Peptides; Ribosomes; Threonine; Valine | 1971 |
Synthesis and assembly of immunoglobulins by malignant human plasmacytes. I. Myelomas producing gamma-chains and light chains.
Topics: Bence Jones Protein; Bone Marrow Examination; Carbon Isotopes; Chromatography, Gel; Culture Techniques; Cytoplasm; Electrophoresis; Glutamates; Humans; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulins; Leucine; Leukemia, Plasma Cell; Multiple Myeloma; Neoplasm Proteins; Plasma Cells; Threonine; Tritium; Ultracentrifugation; Valine | 1970 |