threonine and Lung Neoplasms

threonine has been researched along with Lung Neoplasms in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.26)18.7374
1990's0 (0.00)18.2507
2000's11 (28.95)29.6817
2010's21 (55.26)24.3611
2020's4 (10.53)2.80

Authors

AuthorsStudies
Agorreta, J; Amat, R; Bértolo, C; Bosco, G; Calvo, A; Echepare, M; Felip, E; Frigola, J; López-Picazo, JM; Melero, I; Montuenga, LM; Pasquier, A; Picabea, B; Sainz, C; Tamayo, I; Teijeira, Á; Thomas, R; Valencia, K1
Cao, X; Lai, S; Sun, W; Wang, D1
Cho, JW; Ji, S; Kang, MJ; Kim, E; Kim, YJ; Kweon, TH; Park, YS; Yang, WH; Yi, EC1
Baek, SA; Cha, SI; Choi, JE; Choi, SH; Do Yoo, J; Do, SK; Hong, MJ; Kang, HG; Kim, CH; Kim, JH; Kim, S; Lee, J; Lee, JH; Lee, SY; Lee, WK; Lee, YH; Park, JY; Seo, H; Yoo, SS1
Brooks, AJ; Chhabra, Y; Kragelund, BB; Meunier, FA; Nikolajsen, LF; Papadopulos, A; Smith, AG; Steinocher, H; Tunny, KA; Waters, MJ; Wong, HY1
Barnes, TA; Leighl, NB; O'Kane, GM1
Anwar, T; Arellano-Garcia, C; Basrur, V; Chen, YC; Gonzalez, ME; Grigsby, S; Kidwell, KM; Kim, HS; Kleer, CG; Muntean, A; Nesvizhskii, AI; Nikolovska-Coleska, Z; Ropa, J; Yoon, E1
Bourien, H; Corre, R; Lena, H; Lespagnol, A; Leveiller, G; Prigent, A; Ricordel, C1
Chiu, SY; Chung, HJ; Huang, CC; Huang, MS; Lin, Y; Liu, F; Matsuura, I; Yadav, P1
Du, Y; Huang, Y; Ma, Y; Shi, H; Zhou, Y1
Han, JY; Hwang, JA; Kim, HT; Kim, JH; Kim, SH; Lee, GK; Lee, JS; Lee, Y; Lee, YS; Nam, BH; Yun, T; Zhang, W1
Deng, M; Gu, Y; He, Z; Liu, H; Wang, C; Yin, J1
Asano, H; Furukawa, M; Hagiwara, K; Hashida, S; Miyoshi, S; Shien, K; Soh, J; Tanaka, T; Toyooka, S; Tsukuda, K; Yamamoto, H1
Du, Y; Fu, H; Han, Q; Khuri, FR; Li, Z; Park, HR; Pham, CD; Shi, Z; Zhang, Y1
Dai, B; Fang, B; Gao, W; Gold, KA; Heymach, JV; Hofstetter, WL; Lu, H; Minna, J; Ou, Z; Roth, JA; Swisher, SG; Wang, L; Wang, M; Wu, S; Zhang, L1
Bryan, MC; Burdick, DJ; Chan, BK; Chen, Y; Dotson, J; Eigenbrot, C; Hanan, EJ; Heald, RA; Heffron, TP; Jackson, PS; La, H; Lainchbury, MD; Malek, S; Purkey, HE; Schaefer, G; Schmidt, S; Seward, EM; Sideris, S; Tam, C; Wang, S; Yeap, SK; Yen, I; Yin, J; Yu, C; Zilberleyb, I1
Compton, DA; Dmitrovsky, E; Freemantle, S; Godek, K; Hu, S; Kawakami, M; Lu, Y; Mustachio, LM; Orr, B; Sekula, D1
Huang, L; Jiang, A; Qiao, P; Ren, C; Tang, S; Wang, L; Yang, T; Yu, Z; Zhang, W1
Dong, ZY; Gao, HF; Gou, LY; Li, AN; Liu, SY; Lou, NN; Su, J; Wu, YL; Xie, Z; Xu, CR; Yan, HH; Yang, JJ; Zhang, XC; Zhong, WZ; Zhou, Q1
Armutlulu, A; Balaram, H; Balasubramanian, S; Bartosh, TJ; Broda, M; Brown, LE; Burroughs, LM; Burrows, F; Cardoso, JR; Carregaro, RL; Cho, J; Cui, Q; Dela Bela, LF; Dias, JM; Dutta, NK; Flowers, ME; Gallo, S; Hari, P; He, R; He, Y; Heimfeld, S; Jia, B; Jin, X; Jin, YJ; Karakousis, PC; Karmakar, T; Kiem, HP; Kreager, DA; Lebedev, D; Li, F; Li, S; Liang, N; Liu, Z; Luo, J; Luo, Y; Mazuquin, BF; Meng, Y; Mosialos, G; Moura, FA; Müller, CR; Naeem, MA; Nagappa, LK; Nguyen, H; Pelegrinelli, AR; Pinn, ML; Prahlada Rao, VS; Pulsipher, MA; Ragan, DT; Richards, J; Roy, S; Sandmaier, BM; Selfe, J; Selim, MA; Shi, J; Shi, X; Staff, J; Storb, R; Storer, BE; Wang, F; Wang, M; Wang, S; Woolfrey, AE; Wright, T; Ylostalo, JH; Zhang, JY; Zhang, ZY; Zheng, K; Zhu, Z1
Gao, S; Huang, J; Sixt, KM; Tripathi, V; Weigert, R; Xu, X; Zhang, YE; Zhou, M1
Bates, PA; Dallman, M; Derua, R; Downward, J; Gray, C; Lamb, J; Lara, R; Mauri, FA; Nicols, A; Pardo, OE; Schofield, E; Seckl, MJ; Shia, A; Shiner, RJ; Taylor, H; Waelkens, E; Zicha, D1
Elder, DJ; Hetzel, MR; May, MT; Morgan, C; Pawade, J; Phillips, L; Sohail, M; Tavaré, JM; Thomas, EC; Vincent, EE1
Chang, S; Ding, J; Ding, K; Geng, M; Liu, Y; Lu, X; Luo, J; Pei, D; Ren, X; Tu, Z; Xu, S; Xu, T; Xu, Y; Zhang, L; Zhang, Z1
Men, W; Ren, K; Tang, J; Zhao, J1
Bello, S; Bernal, ML; Fanlo, A; Isla, D; Mayayo, E; Rubio, E; Sinués, B1
LORINCZ, AB; RYAN, WL1
Fujishiro, M; Goshima, Y; Ishii, T; Kitamura, H; Masuda, M; Matsuse, T; Teramoto, S1
Kelsey, KT; Liu, M; McMillan, A; Miike, R; Quesenberry, C; Sison, JD; Wiencke, JK; Wrensch, MR1
Chao, JI; Kuo, PC; Liu, HF1
Reddy, GK1
Clurman, BE; D Tsuchiya, K; Firpo, E; Kostner, H; Loeb, KR; Norwood, T; Roberts, JM1
Bell, DW; Brannigan, BW; Godin-Heymann, N; Gore, I; Haber, DA; Mohapatra, G; Mulloy, R; Okimoto, RA; Settleman, J; Sharma, SV; Sordella, R1
Byrski, T; Castaneda, J; Cybulski, C; Debniak, B; Debniak, T; Górski, B; Huzarski, T; Jaworowska, E; Klujszo-Grabowska, E; Kurzawski, G; Lener, M; Lubinski, J; Masojc, B; Matyjasik, J; Medrek, K; Mierzejewski, M; Narod, S; Nej-Wołosiak, K; Oszurek, O; Oszutowska, D; Rozmiarek, A; Scott, RJ; Suchy, J; Szymańska, A; Szymańska, J; Teodorczyk, U; van de Wetering, T; Złowocka, E1
Li, K; Pardinas, JR; Xiao, L; Zhang, J1
Aoe, K; Aoe, M; Asano, H; Date, H; Ichihara, S; Inukai, M; Ito, S; Kiura, K; Ouchida, M; Shimizu, N; Soh, J; Suehisa, H; Toyooka, S1
Cao, G; Feng, J; Hou, Y; Lu, H; Shu, J; Zheng, D1
Fujita, M; Makita, A; Oikawa, K; Ono, M; Taniguchi, N1

Reviews

2 review(s) available for threonine and Lung Neoplasms

ArticleYear
Resistance to epidermal growth factor receptor tyrosine kinase inhibitors, T790M, and clinical trials.
    Current oncology (Toronto, Ont.), 2018, Volume: 25, Issue:Suppl 1

    Topics: Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Codon, Nonsense; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Lung Neoplasms; Methionine; Molecular Targeted Therapy; Protein Kinase Inhibitors; Research Design; Threonine

2018
Role of epidermal growth factor receptor mutations in predicting sensitivity or resistance to targeted agents in non-small-cell lung cancer.
    Clinical lung cancer, 2005, Volume: 6, Issue:6

    Topics: Amino Acid Substitution; Antineoplastic Agents; Asian People; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Methionine; Mutation; Quinazolines; Sex Factors; Threonine

2005

Other Studies

36 other study(ies) available for threonine and Lung Neoplasms

ArticleYear
DSTYK inhibition increases the sensitivity of lung cancer cells to T cell-mediated cytotoxicity.
    The Journal of experimental medicine, 2022, 12-05, Volume: 219, Issue:12

    Topics: Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; T-Lymphocytes; Threonine; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Tyrosine

2022
Serine/threonine-protein kinase STK24 induces tumorigenesis by regulating the STAT3/VEGFA signaling pathway.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:3

    Topics: A549 Cells; Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Protein Serine-Threonine Kinases; Signal Transduction; STAT3 Transcription Factor; Threonine; Vascular Endothelial Growth Factor A

2023
O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation.
    Scientific reports, 2020, 11-16, Volume: 10, Issue:1

    Topics: Acetylglucosamine; Breast Neoplasms; Female; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Protein Processing, Post-Translational; Proteolysis; Serine; Signal Transduction; Smad4 Protein; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Ubiquitin

2020
Impact of immune checkpoint gene CD155 Ala67Thr and CD226 Gly307Ser polymorphisms on small cell lung cancer clinical outcome.
    Scientific reports, 2021, 01-19, Volume: 11, Issue:1

    Topics: Aged; Alanine; Amino Acid Substitution; Antigens, Differentiation, T-Lymphocyte; Carcinoma, Small Cell; Female; Glycine; Humans; Lung Neoplasms; Male; Polymorphism, Genetic; Receptors, Virus; Serine; Threonine; Treatment Outcome

2021
A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation.
    Oncogene, 2018, 01-25, Volume: 37, Issue:4

    Topics: Animals; Carrier Proteins; Cell Line, Tumor; Cohort Studies; Computational Biology; Disease Progression; DNA Mutational Analysis; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lung; Lung Neoplasms; Magnetic Resonance Spectroscopy; Male; Mice; Phosphorylation; Polymorphism, Single Nucleotide; Proline; Protein Binding; Protein Domains; Proteolysis; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Threonine; Ubiquitin-Protein Ligases; Ubiquitination

2018
p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis.
    Nature communications, 2018, 07-18, Volume: 9, Issue:1

    Topics: Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Lung Neoplasms; Mice; Mice, SCID; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polycomb Repressive Complex 2; RNA, Small Interfering; Survival Analysis; Threonine

2018
[Search for the T790M mutation: The need to persevere].
    Revue des maladies respiratoires, 2018, Volume: 35, Issue:7

    Topics: Aged; Amino Acid Substitution; Biopsy; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation, Missense; Protein Kinase Inhibitors; Threonine; Time Factors

2018
Impaired mammary tumor formation and metastasis by the point mutation of a Smad3 linker phosphorylation site.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:11

    Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Proliferation; Female; Gene Editing; Gene Knock-In Techniques; Humans; Lung Neoplasms; Mice; Mice, SCID; Phosphorylation; Point Mutation; Signal Transduction; Smad3 Protein; Threonine; Transforming Growth Factor beta; Triple Negative Breast Neoplasms; Valine; Xenograft Model Antitumor Assays

2018
Epidermal growth factor receptor T790M mutations in non-small cell lung cancer (NSCLC) of Yunnan in southwestern China.
    Scientific reports, 2018, 10-18, Volume: 8, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; China; Circulating Tumor DNA; Cohort Studies; DNA Mutational Analysis; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation, Missense; Protein Kinase Inhibitors; Threonine

2018
Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations.
    Cancer, 2014, Jul-15, Volume: 120, Issue:14

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asian People; Disease-Free Survival; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation; Neoplasm Staging; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Republic of Korea; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Treatment Outcome; Tumor Cells, Cultured

2014
FOXO3a mediates the cytotoxic effects of cisplatin in lung cancer cells.
    Anti-cancer drugs, 2014, Volume: 25, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Lung Neoplasms; Membrane Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Threonine; Tumor Suppressor Protein p53

2014
Presence of the minor EGFR T790M mutation is associated with drug-sensitive EGFR mutations in lung adenocarcinoma patients.
    Oncology reports, 2014, Volume: 32, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Exons; Female; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation; Sequence Deletion; Threonine

2014
Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs.
    Oncotarget, 2014, May-30, Volume: 5, Issue:10

    Topics: 14-3-3 Proteins; Adenocarcinoma; Amino Acid Motifs; Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Survival; Cell Transformation, Neoplastic; Chromatography, Affinity; Gene Knockdown Techniques; Heterografts; Humans; Immunoprecipitation; Lung Neoplasms; Mice; Mice, SCID; Microfilament Proteins; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Phosphorylation; RNA, Small Interfering; Serine; src Homology Domains; Threonine; Transfection

2014
Selective antitumor activity of ibrutinib in EGFR-mutant non-small cell lung cancer cells.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:9

    Topics: Adenine; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Methionine; Mice; Mutation; Piperidines; Pyrazoles; Pyrimidines; Quinazolines; Threonine

2014
Discovery of selective and noncovalent diaminopyrimidine-based inhibitors of epidermal growth factor receptor containing the T790M resistance mutation.
    Journal of medicinal chemistry, 2014, Dec-11, Volume: 57, Issue:23

    Topics: Amino Acid Substitution; Aminopyridines; Carcinoma, Non-Small-Cell Lung; Crystallography, X-Ray; Drug Resistance, Neoplasm; ErbB Receptors; High-Throughput Screening Assays; Humans; Lung Neoplasms; Methionine; Mutation; Protein Kinase Inhibitors; Threonine

2014
Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:11

    Topics: Anaphase; Animals; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Centrosome; Cyclin-Dependent Kinase 2; Cyclins; Humans; Immunoblotting; Lung Neoplasms; Microtubule-Associated Proteins; Mutation; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Purines; RNA Interference; Roscovitine; Serine; Threonine; Ubiquitin Thiolesterase

2015
PKM2 Thr454 phosphorylation increases its nuclear translocation and promotes xenograft tumor growth in A549 human lung cancer cells.
    Biochemical and biophysical research communications, 2016, 05-13, Volume: 473, Issue:4

    Topics: A549 Cells; Active Transport, Cell Nucleus; Animals; Carrier Proteins; Cell Nucleus; Cell Proliferation; Drug Resistance, Neoplasm; Lung Neoplasms; Membrane Proteins; Mice, Nude; Mitochondria; Pentose Phosphate Pathway; Phosphorylation; Pyruvate Kinase; Threonine; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Xenograft Model Antitumor Assays

2016
The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer.
    Oncotarget, 2016, Aug-09, Volume: 7, Issue:32

    Topics: Adult; Aged; Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation, Missense; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Threonine; Up-Regulation; Young Adult

2016
    Journal of developmental and life-course criminology, 2016, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Amino Acid Substitution; Anemia, Aplastic; Athletes; Athletic Performance; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Catalytic Domain; Cell Count; Child; Child, Preschool; Escherichia coli; Female; Gene Expression; Graft Survival; Graft vs Host Disease; Histocompatibility Testing; Humans; Hydrogen Bonding; Immunosuppression Therapy; Inosine Monophosphate; Integrin alphaVbeta3; Kinetics; Knee Joint; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Middle Aged; Molecular Dynamics Simulation; Muscle, Skeletal; Mutation; Organotechnetium Compounds; Pentosyltransferases; Peptides, Cyclic; Phenylalanine; Plasmodium falciparum; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protozoan Proteins; Radiopharmaceuticals; Recombinant Proteins; Running; Sensitivity and Specificity; Serine; Siblings; Single Photon Emission Computed Tomography Computed Tomography; Soccer; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Threonine; Time Factors; Torque; Treatment Outcome; Tryptophan; Tyrosine; Young Adult

2016
Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β.
    Molecular cell, 2016, 11-03, Volume: 64, Issue:3

    Topics: Alternative Splicing; Animals; Cell Line, Tumor; DNA-Binding Proteins; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Exons; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Hyaluronan Receptors; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; Phosphorylation; Promoter Regions, Genetic; Protein Isoforms; RNA Precursors; RNA-Binding Proteins; Signal Transduction; Smad3 Protein; Threonine; Transforming Growth Factor beta

2016
An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis.
    Oncogene, 2011, Aug-11, Volume: 30, Issue:32

    Topics: Animals; Binding Sites; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Embryo, Nonmammalian; Green Fluorescent Proteins; Humans; Lung Neoplasms; Microfilament Proteins; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasm Transplantation; Phosphoproteins; Phosphorylation; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; RNA, Small Interfering; Threonine; Transplantation, Heterologous; Zebrafish

2011
Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer.
    British journal of cancer, 2011, May-24, Volume: 104, Issue:11

    Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Enzyme Activation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; Serine; Threonine

2011
Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine⁷⁹⁰ → methionine⁷⁹⁰ mutant.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Lung Neoplasms; Methionine; Mice; Mice, Nude; Mice, SCID; Molecular Conformation; Mutation; Neoplasm Transplantation; Pyrimidines; Quinazolines; Structure-Activity Relationship; Threonine; Transplantation, Heterologous

2012
FBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cells.
    FEBS letters, 2012, Dec-14, Volume: 586, Issue:24

    Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cytoskeletal Proteins; DNA Damage; DNA-Binding Proteins; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Humans; Lung Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Proteolysis; Proto-Oncogene Mas; Threonine; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligases

2012
MDR-1 C3435T genetic polymorphism and tobacco-related lung cancer.
    Oncology, 2003, Volume: 64, Issue:2

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Case-Control Studies; Cysteine; Genes, MDR; Genotype; Humans; Lung Neoplasms; Male; Polymorphism, Genetic; Risk Assessment; Risk Factors; Smoking; Threonine

2003
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine

1964
Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells.
    The European respiratory journal, 2004, Volume: 23, Issue:5

    Topics: Adenocarcinoma; Amino Acid Substitution; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Cytoplasm; Enzyme Inhibitors; Glutamic Acid; Humans; Lung Neoplasms; Phosphorylation; Serine; Threonine; Tissue Distribution; Tumor Suppressor Proteins

2004
CYP1A1 variants and smoking-related lung cancer in San Francisco Bay area Latinos and African Americans.
    International journal of cancer, 2005, Jan-01, Volume: 113, Issue:1

    Topics: Aged; Alanine; Black or African American; Case-Control Studies; Confounding Factors, Epidemiologic; Cysteine; Cytochrome P-450 CYP1A1; Female; Genotype; Glycine; Hispanic or Latino; Humans; Linkage Disequilibrium; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; San Francisco; Smoking; Threonine

2005
Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells.
    The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53

    Topics: Apoptosis; Benzothiazoles; Blotting, Western; Carcinoma; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; DNA; Fluorescent Antibody Technique, Indirect; G2 Phase; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Male; Microscopy, Phase-Contrast; Microtubule-Associated Proteins; Middle Aged; Mitosis; Models, Biological; Neoplasm Proteins; Oligonucleotides, Antisense; Phosphorylation; Protein Transport; Quercetin; RNA, Small Interfering; Survivin; Thiazoles; Threonine; Time Factors; Toluene; Transfection; Tumor Suppressor Protein p53

2004
A mouse model for cyclin E-dependent genetic instability and tumorigenesis.
    Cancer cell, 2005, Volume: 8, Issue:1

    Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Chromosome Breakage; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cytogenetic Analysis; Disease Models, Animal; Female; Genomic Instability; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; ras Proteins; Threonine; Translocation, Genetic; Tumor Suppressor Protein p53; Ubiquitin

2005
Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.
    Nature genetics, 2005, Volume: 37, Issue:12

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Female; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Pedigree; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Threonine

2005
CDKN2A common variant and multi-organ cancer risk--a population-based study.
    International journal of cancer, 2006, Jun-15, Volume: 118, Issue:12

    Topics: Adult; Aged; Alanine; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Female; Genes, p16; Genetic Variation; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Odds Ratio; Poland; Prevalence; Risk Assessment; Risk Factors; Threonine

2006
Re: Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
    Journal of the National Cancer Institute, 2006, Mar-01, Volume: 98, Issue:5

    Topics: ErbB Receptors; Gene Deletion; Humans; Lung Neoplasms; Methionine; Mutation; Threonine

2006
Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.
    Cancer research, 2006, Aug-15, Volume: 66, Issue:16

    Topics: Amino Acid Substitution; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Methionine; Mutation; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Threonine

2006
Lung cancer risk associated with Thr495Pro polymorphism of GHR in Chinese population.
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:4

    Topics: Adenocarcinoma; Aged; Asian People; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Chi-Square Distribution; Female; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Proline; Receptors, Somatotropin; Risk Assessment; Risk Factors; Smoking; Threonine

2008
Protein phosphorylation of beta-glucuronidase in human lung cancer--identification of serine- and threonine-phosphates.
    Biochemical and biophysical research communications, 1985, Jan-31, Volume: 126, Issue:2

    Topics: Adenocarcinoma; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Glucuronidase; Humans; Hydrolysis; Immunodiffusion; Liver; Lung; Lung Neoplasms; Phosphorylation; Phosphoserine; Phosphothreonine; Serine; Threonine

1985