Compounds > threonine

threonine and Insulin Sensitivity

threonine has been researched along with Insulin Sensitivity in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.22)18.7374
1990's7 (15.56)18.2507
2000's20 (44.44)29.6817
2010's14 (31.11)24.3611
2020's3 (6.67)2.80

Authors

AuthorsStudies
Chávez-Maldonado, JP; Hiriart, M; Larqué, C; Ortiz-Huidobro, RI; Sabido, J; Sanchez-Zamora, YI; Velasco, M1
Araki, E; Cai, W; Fukuda, K; Fukuda, T; Igata, M; Kahn, CR; Kondo, T; Okagawa, S; Okubo, Y; Otsuka, Y; Sakaguchi, M; Sakaguchi, N; Sato, Y; Tseng, YH; Yamagata, K; Yoshizawa, T1
Hu, L; Ma, Q; Meng, Q; Shan, A; Shao, C; Sun, Y; Zhou, X; Zhu, J1
Camporez, JPG; Corbit, KC; Deo, RC; Edmunds, LR; Erion, DM; Jurczak, MJ; Perry, RJ; Shulman, GI; Tran, JL; Vera, NB; Weiss, EJ1
D'Aquino, K; Feener, EP; King, GL; Li, Q; Maeda, Y; Mima, A; Mizutani, K; Park, K; Rask-Madsen, C; White, MF; Winnay, J1
Aller, R; Conde, R; de Luis, DA; Gonzalez Sagrado, M; Izaola, O1
Costa, JD; Crispim, D; Dora, JM; Leiria, LB; Lopes, MG; Maia, AL; Pinto Ribeiro, RV; Vitali da Silva, A; Wajner, SM1
Cao, D; Liu, Z; Ma, F; Ouyang, S; Wu, J1
Gastecki, ML; Jurrissen, TJ; Padilla, J; Rector, RS; Sheldon, RD; Vieira-Potter, VJ; Woodford, ML; Zidon, TM1
Anilkumar, N; Crossey, PA; Douglas, G; Duncan, ER; Ezzat, VA; Kearney, MI; Kearney, MT; Poston, L; Shah, AM; Walker, S; Wheatcroft, SB1
Cartee, GD; Funai, K; Kanzaki, M; Schweitzer, GG; Sharma, N1
Boerwinkle, E; Chamberlain, AM; Fornage, M; Loria, CM; Schreiner, PJ; Siscovick, D1
Aller, R; Conde, R; de Luis, DA; Izaola, O; Romero, E; Sagrado, MG1
Arellano-Plancarte, A; Catt, KJ; Hernandez-Aranda, J; Olivares-Reyes, JA1
Bourron, O; Daval, M; Ferré, P; Foufelle, F; Gautier, JF; Hainault, I; Hajduch, E; Servant, JM1
Diamant, M; Guigas, B; Jazet, IM; Kriek, J; Maassen, JA; Nascimento, EB; Ouwens, DM; Snel, M; van der Zon, GC1
Elks, CM; Francis, J1
Ballesteros, M; Conde, R; Cordero, M; de Luis, DA; Gonzalez Sagrado, M; Iglesias, P; Izaola, O; Lopez Guzman, A; Maldonado, A; Muñoz, C; Penacho, MA; Puigdevall, V; Romero, E; Ruiz, E; San Martin, L1
De Filippis, E; Finlayson, J; Langlais, P; Luo, M; Mandarino, LJ; Mapes, R; Mattern, M; Meyer, C; Plummer, E; Tongchinsub, P; Yi, Z1
Blough, ER; Kakarla, SK; Katta, A; Kolli, MB; Kundla, S; Manne, ND; Nalabotu, SK; Wu, M1
Copps, KD; White, MF1
Erkkilä, AT; Laakso, M; Lehto, S; Lindi, V; Pyörälä, K; Uusitupa, MI1
Furuhashi, M; Higashiura, K; Hyakukoku, M; Murakami, H; Shimamoto, K; Togashi, N; Ura, N; Wang, L; Yamaguchi, K1
RIESER, CH; RIESER, P1
Schmitz-Peiffer, C; Whitehead, JP1
Albala, C; Angel, B; Cifuentes, M; Lera, L; Liberman, C; Pérez-Bravo, F; Santos, JL; Villarroel, AC1
Zick, Y1
Kaneki, M; Martyn, JA; Sugita, H; Sugita, M; Yasuhara, S; Yasukawa, T1
Kondo, H; Shimomura, I1
Hirose, H; Ishii, T1
Bianco, AC; Canani, LH; Capp, C; Dora, JM; Gross, JL; Harney, JW; Larsen, PR; Maia, AL; Meyer, EL; Wagner, MS1
Andersen, G; Borch-Johnsen, K; Drivsholm, T; Glümer, C; Hamid, YH; Hansen, T; Jørgensen, T; Pedersen, O; Rose, CS1
Birnbaum, MJ; Bruce, CR; Carey, AL; Febbraio, MA; Hawley, JA; Monks, R; Southgate, RJ; Steinberg, GR; Walder, K; Watt, MJ1
Albala, C; Angel, B; Lera, L; Liberman, C; Pérez-Bravo, F; Sanchez, H; Santos, JL; Villarroel, A1
Canani, LH; Capp, C; Leie, MA; Machado, WE; Maia, AL1
Feinstein, R; Hemi, R; Kanety, H; Karasik, A; Papa, MZ1
Capp, E; Coghlan, M; Galante, P; Häring, HU; Kellerer, M; Kroder, G; Mosthaf, L; Mühlhöfer, A; Siddle, K1
Baier, LJ; Bennett, PH; Bogardus, C; Eads, J; Knowler, WC; Mochizuki, H; Paolisso, G; Prochazka, M; Sacchettini, JC; Tataranni, PA1
Bogardus, C; Janssen, RC; Knowler, WC; Takeda, J; Thompson, DB1
Ichikawa, F; Ishiyama, S; Koyama, K; Koyama, W; Koyanagi, A; Nonaka, K; Yamada, K; Yuan, X1
Benito, M; Lorenzo, M; Teruel, T; Valverde, AM1
Ding, W; Jia, W; Lu, J; Sun, D; Tang, J; Xiang, K; Zheng, T1
Hemi, R; Kanety, H; Karasik, A; Paz, K; Wertheim, N; Zick, Y1
Bacci, V; Celi, FS; Mentuccia, D; Poehlman, ET; Pollin, TI; Proietti-Pannunzi, L; Shuldiner, AR; Tanner, K1
Allibardi, S; Bendinelli, P; Luzi, L; Maroni, P; Piccoletti, R; Samaja, M; Terruzzi, I; Vesco, F1

Reviews

7 review(s) available for threonine and Insulin Sensitivity

ArticleYear
Association of the ADIPOQ T45G polymorphism with insulin resistance and blood glucose: a meta-analysis.
    Endocrine journal, 2014, Volume: 61, Issue:5

    Topics: Adiponectin; Amino Acid Substitution; Blood Glucose; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Genetic Association Studies; Genetic Predisposition to Disease; Glycine; Humans; Insulin Resistance; Polymorphism, Single Nucleotide; Threonine

2014
Central adiposity, systemic inflammation, and the metabolic syndrome.
    Current hypertension reports, 2010, Volume: 12, Issue:2

    Topics: Abdominal Fat; Adipokines; Adiponectin; Adiposity; C-Reactive Protein; Cytokines; Diet; Humans; Inflammation; Insulin Resistance; Interleukins; Leptin; Life Style; Metabolic Syndrome; NF-kappa B; Nutritional Status; Oxidative Stress; Risk Factors; Serine; Threonine; Tumor Necrosis Factor-alpha

2010
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2.
    Diabetologia, 2012, Volume: 55, Issue:10

    Topics: Animals; Diabetes Mellitus; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Mice, Knockout; Mice, Transgenic; Models, Animal; Phosphorylation; Serine; Signal Transduction; Threonine

2012
IRS-1 regulation in health and disease.
    IUBMB life, 2003, Volume: 55, Issue:7

    Topics: Animals; Cysteine Endopeptidases; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Models, Biological; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase C; Serine; Signal Transduction; Threonine

2003
Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance.
    Biochemical Society transactions, 2004, Volume: 32, Issue:Pt 5

    Topics: Animals; Binding Sites; Humans; Insulin; Insulin Resistance; Models, Biological; Phosphorylation; Serine; Signal Transduction; Threonine

2004
[I164T polymorphism of adiponectin gene in diabetes].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 2

    Topics: Adiponectin; Amino Acid Substitution; Animals; Diabetes Mellitus; Genetic Predisposition to Disease; Humans; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Isoleucine; Mutation, Missense; Threonine

2005
[Fatty acid binding protein-2 (FABP2) gene polymorphism in diabetes].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 2

    Topics: Adipocytes; Alanine; Amino Acid Substitution; Carrier Proteins; Diabetes Mellitus; Fatty Acid-Binding Proteins; Fatty Acids, Nonesterified; Genetic Predisposition to Disease; Glucose Intolerance; Humans; Insulin Resistance; Lipid Peroxidation; Polymorphism, Genetic; Racial Groups; Threonine

2005

Trials

1 trial(s) available for threonine and Insulin Sensitivity

ArticleYear
Fatty acid-binding protein 2 Ala54Thr genotype is associated with insulin resistance and leptin levels changes after a high monounsaturated fat diet in obese non-diabetic patients.
    Journal of endocrinological investigation, 2013, Volume: 36, Issue:6

    Topics: Adult; Alanine; Amino Acid Substitution; Diet, High-Fat; Dietary Fats, Unsaturated; Fatty Acid-Binding Proteins; Female; Genotype; Humans; Insulin Resistance; Leptin; Male; Middle Aged; Mutation, Missense; Obesity; Polymorphism, Single Nucleotide; Threonine

2013

Other Studies

37 other study(ies) available for threonine and Insulin Sensitivity

ArticleYear
Sexual dimorphism in the molecular mechanisms of insulin resistance during a critical developmental window in Wistar rats.
    Cell communication and signaling : CCS, 2022, 10-12, Volume: 20, Issue:1

    Topics: Animals; Blood Glucose; Female; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Sex Characteristics; Threonine

2022
Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling.
    Nature communications, 2022, 10-14, Volume: 13, Issue:1

    Topics: Adipocytes; Animals; Diabetes Mellitus, Type 2; Homeostasis; Insulin; Insulin Resistance; Male; Mice; Phosphorylation; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Serine; Threonine; Tyrosine

2022
Threonine, but Not Lysine and Methionine, Reduces Fat Accumulation by Regulating Lipid Metabolism in Obese Mice.
    Journal of agricultural and food chemistry, 2020, Apr-29, Volume: 68, Issue:17

    Topics: Adipose Tissue, Brown; Animals; Anti-Obesity Agents; Diet, High-Fat; Humans; Insulin Resistance; Lipid Metabolism; Lipogenesis; Lysine; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Threonine; Uncoupling Protein 1

2020
Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling.
    Diabetes, 2018, Volume: 67, Issue:2

    Topics: Adipose Tissue; Adiposity; Animals; Diet, High-Fat; Insulin Resistance; Janus Kinase 2; Lipid Metabolism; Liver; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Non-alcoholic Fatty Liver Disease; Obesity; Organ Specificity; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Signal Transduction; Threonine

2018
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells.
    Molecular and cellular biology, 2013, Volume: 33, Issue:16

    Topics: Angiotensin II; Animals; Cattle; Cell Line; Endothelial Cells; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

2013
Type 2 deiodinase Thr92Ala polymorphism is associated with disrupted placental activity but not with dysglycemia or adverse gestational outcomes: a genetic association study.
    Fertility and sterility, 2014, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Alanine; Blood Glucose; Cross-Sectional Studies; Female; Genetic Association Studies; Humans; Infant, Newborn; Insulin Resistance; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Middle Aged; Placenta; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Outcome; Threonine; Young Adult

2014
Ablation of eNOS does not promote adipose tissue inflammation.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2016, Apr-15, Volume: 310, Issue:8

    Topics: Adipose Tissue, Brown; Adiposity; Animals; Diet, High-Fat; Disease Models, Animal; Genetic Predisposition to Disease; Inflammation Mediators; Insulin Resistance; Intra-Abdominal Fat; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Panniculitis; Phenotype; Phosphorylation; Serine; Signal Transduction; Threonine

2016
Effect of endothelium-specific insulin resistance on endothelial function in vivo.
    Diabetes, 2008, Volume: 57, Issue:12

    Topics: Alanine; Amino Acid Substitution; Animals; beta-Galactosidase; Blood Glucose; Cloning, Molecular; Endothelium, Vascular; Glucose Tolerance Test; Homeostasis; Humans; Insulin Resistance; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Plasmids; Polymerase Chain Reaction; Receptor, Insulin; Reverse Transcriptase Polymerase Chain Reaction; Threonine

2008
Increased AS160 phosphorylation, but not TBC1D1 phosphorylation, with increased postexercise insulin sensitivity in rat skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:1

    Topics: Animals; Biological Transport; Glucose; Glycogen; GTPase-Activating Proteins; Insulin Resistance; Male; Muscle, Skeletal; Oncogene Protein v-akt; Phosphorylation; Physical Conditioning, Animal; Protein Kinases; Proteins; Rats; Rats, Wistar; Threonine; Up-Regulation

2009
Ala54Thr polymorphism of the fatty acid binding protein 2 gene and saturated fat intake in relation to lipid levels and insulin resistance: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
    Metabolism: clinical and experimental, 2009, Volume: 58, Issue:9

    Topics: Adult; Alanine; Amino Acid Substitution; Cohort Studies; Coronary Artery Disease; Dietary Fats; Eating; Fatty Acid-Binding Proteins; Fatty Acids; Female; Humans; Insulin Resistance; Lipid Metabolism; Male; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Young Adult

2009
Ala54Thr polymorphism of fatty acid binding protein 2, role on insulin resistance and cardiovascular risk factors in presurgical morbid obesity patients.
    Obesity surgery, 2009, Volume: 19, Issue:12

    Topics: Adipokines; Adult; Alanine; Alleles; C-Reactive Protein; Cholesterol; Fatty Acid-Binding Proteins; Female; Gene Frequency; Humans; Insulin Resistance; Male; Middle Aged; Obesity, Morbid; Polymorphism, Genetic; Risk Factors; Threonine; Triglycerides

2009
Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells.
    Biochemical pharmacology, 2010, Mar-01, Volume: 79, Issue:5

    Topics: Angiotensin II; Animals; Cell Line; Enzyme Inhibitors; ErbB Receptors; Hepatocytes; Insulin; Insulin Resistance; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Receptor, Insulin; Serine; Signal Transduction; Threonine; Transcriptional Activation; Tyrphostins; Vasoconstrictor Agents

2010
Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase.
    Diabetologia, 2010, Volume: 53, Issue:4

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Adult; Amino Acid Substitution; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Bariatric Surgery; Biguanides; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Humans; Insulin Resistance; Lipolysis; Overweight; Patient Selection; Ribonucleotides; Serine; Thiazolidinediones; Threonine

2010
Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.
    Cellular signalling, 2010, Volume: 22, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Cell Line; Enzyme Inhibitors; Humans; Insulin; Insulin Resistance; Mice; Muscle, Skeletal; NIH 3T3 Cells; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Serine; Sirolimus; Threonine; Transcription Factors; Wortmannin

2010
Polymorphism Ala54Thr of fatty acid-binding protein 2: Allelic frequencies and influence on cardiovascular risk factors in a multicenter study of Castilla y Leon.
    Annals of nutrition & metabolism, 2010, Volume: 57, Issue:3-4

    Topics: Adult; Alanine; Anthropometry; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Insulin Resistance; Male; Mutation; Obesity; Phenotype; Polymorphism, Genetic; Risk Factors; Spain; Threonine

2010
Global IRS-1 phosphorylation analysis in insulin resistance.
    Diabetologia, 2011, Volume: 54, Issue:11

    Topics: Adult; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Middle Aged; Obesity; Phosphorylation; Protein Processing, Post-Translational; Quadriceps Muscle; Serine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Threonine

2011
Diminished muscle growth in the obese Zucker rat following overload is associated with hyperphosphorylation of AMPK and dsRNA-dependent protein kinase.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 113, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; eIF-2 Kinase; Extracellular Signal-Regulated MAP Kinases; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Phosphorylation; Rats; Rats, Zucker; Serine; Signal Transduction; Threonine; Tyrosine; Ubiquitination

2012
Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2002, Volume: 12, Issue:2

    Topics: Adult; Aged; Alanine; Alleles; Blood Pressure; Body Mass Index; Carrier Proteins; Codon; Coronary Disease; Cross-Sectional Studies; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Female; Finland; Gene Frequency; Genetic Variation; Genotype; Humans; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Middle Aged; Neoplasm Proteins; Polymorphism, Genetic; Threonine; Tumor Suppressor Proteins

2002
Tissue-specific impairment of insulin signaling in vasculature and skeletal muscle of fructose-fed rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:2

    Topics: Animals; Aorta, Thoracic; Dietary Sucrose; Fructose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phosphoproteins; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Threonine; Tyrosine

2003
REVERSAL OF INSULIN RESISTANCE IN RED CELL SUGAR TRANSPORT.
    Archives of biochemistry and biophysics, 1964, Volume: 105

    Topics: Arabinose; Biological Transport; Carbohydrate Metabolism; Chymotrypsin; Erythrocytes; Fructose; Galactose; Glycerol; Insulin; Insulin Resistance; Lipase; Mannose; Permeability; Pharmacology; Phospholipases; Research; Ribose; Sorbose; Threonine; Urea; Valine; Xylose

1964
Intestinal FABP2 A54T polymorphism: association with insulin resistance and obesity in women.
    Obesity research, 2004, Volume: 12, Issue:2

    Topics: Adult; Alanine; Alleles; Body Mass Index; Carrier Proteins; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genotype; Humans; Insulin Resistance; Middle Aged; Obesity; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Threonine; Tumor Necrosis Factor-alpha

2004
Burn injury impairs insulin-stimulated Akt/PKB activation in skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:3

    Topics: Animals; Blood Glucose; Burns; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoblotting; Insulin; Insulin Resistance; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Threonine

2005
The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:6

    Topics: Alanine; Amino Acid Substitution; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Kinetics; Polymorphism, Single Nucleotide; Threonine

2005
Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion.
    Diabetic medicine : a journal of the British Diabetic Association, 2005, Volume: 22, Issue:7

    Topics: Adult; Alanine; Blood Glucose; Case-Control Studies; Codon; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Glucose Tolerance Test; Glucose Transport Proteins, Facilitative; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Monosaccharide Transport Proteins; Phenotype; Polymorphism, Genetic; Threonine

2005
PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:14

    Topics: Animals; Biopsy; Cell Nucleus; Cells, Cultured; Down-Regulation; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Enzymologic; Heat-Shock Proteins; Humans; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Models, Biological; Muscle, Skeletal; Oxygen; Palmitic Acid; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Promoter Regions, Genetic; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; RNA, Messenger; Serine; Threonine; Transcription Factors; Transcription, Genetic

2005
FABP2 Ala54Thr polymorphism and diabetes in Chilean elders.
    Diabetes research and clinical practice, 2007, Volume: 77, Issue:2

    Topics: Aged; Alanine; Amino Acid Substitution; Chile; Cross-Sectional Studies; Diabetes Mellitus, Type 2; DNA; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genotype; Humans; Insulin Resistance; Leukocytes; Male; Threonine

2007
Type 2 deiodinase Thr92Ala polymorphism is not associated with arterial hypertension in type 2 diabetes mellitus patients.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:6

    Topics: Alanine; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Hypertension; Insulin Resistance; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Middle Aged; Polymorphism, Single Nucleotide; Reproducibility of Results; Risk Factors; Threonine

2007
Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1.
    The Journal of biological chemistry, 1995, Oct-06, Volume: 270, Issue:40

    Topics: Alkaloids; Animals; Enzyme Inhibitors; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein Tyrosine Phosphatases; Rats; Receptor, Insulin; Serine; Staurosporine; Threonine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine

1995
Mechanism of insulin receptor kinase inhibition in non-insulin-dependent diabetes mellitus patients. Phosphorylation of serine 1327 or threonine 1348 is unaltered.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:1

    Topics: Aged; Aged, 80 and over; Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Middle Aged; Phosphorylation; Rats; Receptor, Insulin; Serine; Threonine

1995
An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:3

    Topics: Adult; Alanine; Alleles; Arizona; Base Sequence; Calorimetry; Carrier Proteins; Chromosomes, Human, Pair 4; Diabetes Mellitus, Type 2; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Female; Gene Frequency; Glucose; Glucose Clamp Technique; Humans; Indians, North American; Insulin Resistance; Male; Models, Molecular; Molecular Sequence Data; Neoplasm Proteins; Oxidation-Reduction; Point Mutation; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Threonine; Tumor Suppressor Proteins

1995
Linkage analysis of acute insulin secretion with GLUT2 and glucokinase in Pima Indians and the identification of a missense mutation in GLUT2.
    Diabetes, 1994, Volume: 43, Issue:4

    Topics: Amino Acid Sequence; Arizona; Base Sequence; Diabetes Mellitus, Type 2; DNA Primers; Epidemiologic Methods; Family; Genetic Linkage; Glucokinase; Glucose Transporter Type 2; Humans; Indians, North American; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Longitudinal Studies; Molecular Sequence Data; Monosaccharide Transport Proteins; Point Mutation; Polymerase Chain Reaction; Threonine

1994
Association between Ala54Thr substitution of the fatty acid-binding protein 2 gene with insulin resistance and intra-abdominal fat thickness in Japanese men.
    Diabetologia, 1997, Volume: 40, Issue:6

    Topics: Abdomen; Adipose Tissue; Alanine; Body Mass Index; Carrier Proteins; DNA; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Heterozygote; Homozygote; Humans; Insulin Resistance; Japan; Leukocytes; Male; Middle Aged; Myelin P2 Protein; Neoplasm Proteins; Point Mutation; Polymorphism, Genetic; Threonine; Tumor Suppressor Proteins

1997
Alterations in the insulin signaling pathway induced by immortalization and H-ras transformation of brown adipocytes.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: Adipocytes; Adipose Tissue, Brown; Alkaline Phosphatase; Animals; Blotting, Western; Cell Line, Transformed; Dose-Response Relationship, Drug; Fetus; Guanosine Triphosphate; Insulin; Insulin Resistance; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Receptor, Insulin; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection

1997
The impact of codon 54 variation in intestinal fatty acid binding protein gene on the pathogenesis of diabetes mellitus in Chinese.
    Chinese medical journal, 1999, Volume: 112, Issue:2

    Topics: Alanine; Asian People; Carrier Proteins; China; Codon; Diabetes Mellitus, Type 2; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Genetic Variation; Humans; Insulin; Insulin Resistance; Insulin Secretion; Neoplasm Proteins; Threonine; Tumor Suppressor Proteins

1999
Transactivation of ErbB2 and ErbB3 by tumor necrosis factor-alpha and anisomycin leads to impaired insulin signaling through serine/threonine phosphorylation of IRS proteins.
    The Journal of biological chemistry, 2002, Mar-15, Volume: 277, Issue:11

    Topics: Anisomycin; Cycloheximide; Genes, erbB; Genes, erbB-2; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Neuregulin-1; Phosphatidylinositol 3-Kinases; Phosphoproteins; Serine; Threonine; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tyrosine

2002
Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor.
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Alanine; Blood Glucose; Glucose Clamp Technique; Heterozygote; Homozygote; Humans; Insulin; Insulin Resistance; Iodide Peroxidase; Isoenzymes; Middle Aged; Mutation, Missense; Obesity; Receptors, Adrenergic, beta-3; Threonine

2002
Amino acid- and lipid-induced insulin resistance in rat heart: molecular mechanisms.
    Molecular and cellular endocrinology, 2002, Apr-25, Volume: 190, Issue:1-2

    Topics: Amino Acids; Animals; Biological Transport; Glucose; Glycogen Synthase Kinase 3; Heart; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Mitogen-Activated Protein Kinases; Myocardium; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Threonine; Tyrosine

2002