threonine has been researched along with Inflammation in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.86) | 18.7374 |
| 1990's | 2 (5.71) | 18.2507 |
| 2000's | 13 (37.14) | 29.6817 |
| 2010's | 14 (40.00) | 24.3611 |
| 2020's | 5 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ábrányi-Balogh, P; Csányi, D; Ferenczy, GG; Gobec, M; Gobec, S; Gömöry, Á; Imre, T; Keserű, GM; Knez, D; Kollár, L; Petri, L; Proj, M; Smrdel, L; Sosič, I | 1 |
| Avril, S; Diehl, JA; Koivisto, C; Leone, G; Phillips-Mason, P; Tarallo, V; Yoshida, A | 1 |
| Lin, X; Tu, H; Xiong, W; Zhang, J; Zhao, X | 1 |
| Chen, P; Chu, Y; Dai, Y; Ke, D; Li, L; Liu, J; Sun, X; Zhang, Z | 1 |
| Banno, A; Jadhav, SK; Kim, SC; Lakshmi, SP; Pulikkal Kadamberi, I; Reddy, AT; Reddy, RC | 1 |
| Massoud, A; Mohammadzadeh, M; Najafi, S; Rezaei, N; Zare Bidoki, A | 1 |
| Chen, Y; Cheng, Y; Li, Y; Wen, C; Zhang, H; Zhou, Y | 1 |
| Asara, JM; Attri, KS; Bhinderwala, F; Gong, W; Green, DR; Herring, LE; Kalil, AC; Lei, YL; Lewis, RE; Li, T; Li, X; Powers, R; Rodriguez, DA; Singh, PK; Wang, H; Wen, H; Yang, M; Yang, X; Yin, G | 1 |
| Giogha, C; Lawlor, KE | 1 |
| Dilger, RN; Jenkins, MC; Wils-Plotz, EL | 1 |
| Jang, SK; Kim, AK; Kim, JH; Kim, JY; Wei, JD | 1 |
| Liu, XJ; Xu, J; Xu, MJ; Zhang, ZG | 1 |
| Du, J; Liu, J; Wang, Y; Yang, Y | 1 |
| Raivich, G | 1 |
| Breuillé, D; Buffière, C; Dardevet, D; Faure, M; Godin, JP; Mirand, PP; Obled, C; Papet, I; Rémond, D; Williamson, G | 1 |
| Barbiroli, A; Bernini, F; Bonomi, F; Calabresi, L; Favari, E; Franceschini, G; Gomaraschi, M; Iametti, S; Pozzi, S; Putt, WE; Talmud, PJ | 1 |
| Elks, CM; Francis, J | 1 |
| Reismann, P | 1 |
| Chen, HJ; Hu, F; Wang, J; Wang, Y; Xie, WY; Zhang, Y | 1 |
| Argenziano, M; Besana, A; Comas, GM; Danilo, P; Feinmark, SJ; Harleton, E; Robinson, RB; Rosen, MR; Rosen, TS | 1 |
| Fan, ST; Li, J; Liu, XJ; Wang, YH; Wu, Z; Xu, J; Xu, MJ; Yang, XM; Zhang, ZG | 1 |
| Bérard, MP; Chaïb, S; Cynober, L; De Bandt, JP; Neveux, N; Osowska, S | 1 |
| Abereoje, OA; Abudu, A; Agbani, EO; Awe, T; Fakoya, FA; Orafidiya, LO | 1 |
| Bahr, I; Dernedde, J; Kilian, K; Mueller, EC; Tauber, R | 1 |
| Choi, SJ; Choi, SW; Firatli, E; Hart, PS; Hart, TC; Ryu, OH; Shen, RF; Wang, G; Wu, WW | 1 |
| Fu, X; Green, PS; Heinecke, JW; McDonald, TO; O'Brien, KD; Oram, JF; Shao, B; Uchida, K | 1 |
| Brunet, A; David-Dufilho, M; Millanvoye-Van Brussel, E; Rendu, F; Topal, G; Walch, L | 1 |
| Ballard, DW; Carter, RS; Gomez, RJ; Khan, WN; Kray, AE; Llanes, JM; Pennington, KN; Sanders, LE; Wadzinski, BE | 1 |
| Bottomley, SP; Coughlin, PB; Horvath, AJ; Irving, JA; Law, RH; Pike, RN; Quinsey, NS; Rossjohn, J; Whisstock, JC | 1 |
| Liu, Y; Miltyk, W; Phang, JM; Surazynski, A | 1 |
| Forman, HJ; Iles, KE; Liu, H; Merrill, G; Rinna, A; Torres, M; Yodoi, J; Zhang, H | 1 |
| Brandes, R; Corvey, N; Dingermann, T; Hörnig, M; Lechtken, A; Steinhilber, D; Werz, O; Zündorf, I | 1 |
| Davis, RJ; Dickens, M; Gupta, S; Han, J; Raingeaud, J; Rogers, JS; Ulevitch, RJ | 1 |
| Anderson, MM; Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
| Björnesjö, KB | 1 |
3 review(s) available for threonine and Inflammation
| Article | Year |
|---|---|
RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications.
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Humans; Inflammation; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Threonine | 2023 |
c-Jun expression, activation and function in neural cell death, inflammation and repair.
Topics: Animals; Cell Death; Gene Expression; Humans; Inflammation; Models, Biological; Neurons; Proto-Oncogene Proteins c-jun; Recovery of Function; Serine; Threonine | 2008 |
Central adiposity, systemic inflammation, and the metabolic syndrome.
Topics: Abdominal Fat; Adipokines; Adiponectin; Adiposity; C-Reactive Protein; Cytokines; Diet; Humans; Inflammation; Insulin Resistance; Interleukins; Leptin; Life Style; Metabolic Syndrome; NF-kappa B; Nutritional Status; Oxidative Stress; Risk Factors; Serine; Threonine; Tumor Necrosis Factor-alpha | 2010 |
2 trial(s) available for threonine and Inflammation
| Article | Year |
|---|---|
Dietary l-threonine supplementation attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier damage of broiler chickens at an early age.
Topics: Animal Feed; Animals; Chickens; Diet; Dietary Supplements; Gene Expression Regulation; Inflammation; Intestinal Mucosa; Intestines; Lipopolysaccharides; Male; Poultry Diseases; Threonine | 2018 |
Modulation of the intestinal environment, innate immune response, and barrier function by dietary threonine and purified fiber during a coccidiosis challenge in broiler chicks.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Coccidiosis; Cytokines; Diet; Dietary Fiber; Dietary Supplements; Gene Expression Regulation; Immunity, Innate; Inflammation; Intestines; Male; Poultry Diseases; RNA, Messenger; Threonine | 2013 |
30 other study(ies) available for threonine and Inflammation
| Article | Year |
|---|---|
Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads.
Topics: Autoimmune Diseases; Benzoxazoles; Computational Chemistry; Cysteine; Hematologic Neoplasms; Humans; Inflammation; Models, Molecular; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Structure-Activity Relationship; Threonine; Ubiquitin | 2021 |
Non-phosphorylatable cyclin D1 mutant potentiates endometrial hyperplasia and drives carcinoma with Pten loss.
Topics: Animals; Carcinoma; Cyclin D1; Cyclin-Dependent Kinase 4; Endometrial Hyperplasia; Female; Humans; Inflammation; Mice; PTEN Phosphohydrolase; Threonine | 2022 |
Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation.
Topics: Animals; Apoptosis; Inflammation; Mice; Phosphorylation; Protein Kinases; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 2022 |
Cigarette smoke downregulates Nur77 to exacerbate inflammation in chronic obstructive pulmonary disease (COPD).
Topics: Animals; Down-Regulation; Epithelial Cells; Humans; Inflammation; Lung; Mice; Nicotiana; Nuclear Receptor Subfamily 4, Group A, Member 1; Phosphorylation; Pulmonary Disease, Chronic Obstructive; Smoke; Threonine | 2020 |
Autosomal dominant deficiency of the interleukin-17F in recurrent aphthous stomatitis: Possible novel mutation in a new entity.
Topics: Algorithms; Case-Control Studies; Female; Gene Frequency; Genes, Dominant; Genetic Predisposition to Disease; Genotype; Heterozygote; Humans; Inflammation; Interleukin-17; Iran; Male; Mutation, Missense; Polymerase Chain Reaction; Probability; Proline; Sequence Analysis, DNA; Software; Stomatitis, Aphthous; Threonine | 2018 |
O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Topics: Animals; Apoptosis; Cell Line; Glucose; Humans; Immunity, Innate; Inflammation; Mice; Mice, Inbred C57BL; N-Acetylglucosaminyltransferases; Necrosis; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine | 2019 |
Sugar Fix Keeps RIPK3 at Bay.
Topics: Humans; Inflammation; N-Acetylglucosaminyltransferases; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Sugars; Threonine | 2019 |
RanBPM protein acts as a negative regulator of BLT2 receptor to attenuate BLT2-mediated cell motility.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Chemotaxis; CHO Cells; Cricetinae; Cricetulus; Cytoskeletal Proteins; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Leukotrienes; Ligands; Nuclear Proteins; Phosphorylation; Protein Structure, Tertiary; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Signal Transduction; Threonine | 2013 |
New Anti-Fibrotic Drug Candidates from Mangrove-Derived Streptomyces xiamenensis Suppressing Local Inflammation and Mechanical Stress in Hypertrophic Scars.
Topics: Animals; Benzopyrans; Cicatrix, Hypertrophic; Fibrosis; Inflammation; Mice; Molecular Structure; Skin; Streptomyces; Stress, Mechanical; Structure-Activity Relationship; Threonine; Wetlands | 2015 |
Phosphorylation of TRPV1 by cyclin-dependent kinase 5 promotes TRPV1 surface localization, leading to inflammatory thermal hyperalgesia.
Topics: Alanine; Animals; Calcium; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Humans; Hyperalgesia; Inflammation; Kinesins; Male; Mutation; Neurons; Peptides; Phosphorylation; Phosphotransferases; Rats; Rats, Sprague-Dawley; Threonine; TRPV Cation Channels | 2015 |
Intestinal inflammation increases gastrointestinal threonine uptake and mucin synthesis in enterally fed minipigs.
Topics: Animal Feed; Animals; Gastrointestinal Tract; Ileitis; Inflammation; Mucins; Swine; Swine, Miniature; Threonine; Trinitrobenzenesulfonic Acid | 2009 |
Structure and function of the apoA-IV T347S and Q360H common variants.
Topics: Amino Acid Substitution; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins A; Cell Line; Cholesterol; Endothelium, Vascular; Glutamine; Histidine; Homeostasis; Humans; Inflammation; Interleukin-6; Lipid Metabolism; Lipoproteins, HDL; Mice; Protein Structure, Secondary; Serine; Threonine; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2010 |
[Study of the Toll-like receptor 4 gene polymorphisms in diseases presenting with subclinical and chronic inflammation].
Topics: Alleles; Aspartic Acid; Brain Ischemia; Chronic Disease; Cytokines; Diabetes Complications; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Glycine; Humans; Inflammation; Isoleucine; Periodontitis; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Stroke; Threonine; Toll-Like Receptor 4 | 2011 |
Disruption of δ-opioid receptor phosphorylation at threonine 161 attenuates morphine tolerance in rats with CFA-induced inflammatory hypersensitivity.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Disease Models, Animal; Drug Tolerance; Hyperalgesia; Hypersensitivity; Inflammation; Male; Morphine; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Threonine | 2012 |
Ability to induce atrial fibrillation in the peri-operative period is associated with phosphorylation-dependent inhibition of TWIK protein-related acid-sensitive potassium channel 1 (TASK-1).
Topics: Animals; Atrial Fibrillation; CHO Cells; Cricetinae; Cricetulus; Dogs; Electrophysiology; Humans; Inflammation; Male; Muscle Cells; Nerve Tissue Proteins; Perioperative Period; Peroxidase; Phosphorylation; Platelet Activating Factor; Potassium Channels, Tandem Pore Domain; Protein Kinase C; Threonine | 2013 |
Xiamenmycin attenuates hypertrophic scars by suppressing local inflammation and the effects of mechanical stress.
Topics: Animals; Benzopyrans; CD4-Positive T-Lymphocytes; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Disease Models, Animal; Female; Fibroblasts; Focal Adhesion Kinase 1; Humans; In Vitro Techniques; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Stress, Mechanical; Threonine | 2013 |
Efficiency of a cysteine-taurine-threonine-serine supplemented parenteral nutrition in an experimental model of acute inflammation.
Topics: Acute Disease; Animals; Cysteine; Dietary Supplements; Inflammation; Male; Parenteral Nutrition; Prospective Studies; Rats; Rats, Sprague-Dawley; Serine; Taurine; Threonine | 2003 |
An investigation into the wound-healing properties of essential oil of Ocimum gratissimum linn.
Topics: Administration, Cutaneous; Animals; Bacitracin; Cysteine; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Glycine; Inflammation; Medicine, African Traditional; Neomycin; Nigeria; Oils, Volatile; Ointments; Phytotherapy; Plant Oils; Rabbits; Random Allocation; Threonine; Wound Healing; Wounds and Injuries | 2003 |
The interaction of protein kinase C isozymes alpha, iota, and theta with the cytoplasmic domain of L-selectin is modulated by phosphorylation of the receptor.
Topics: Amino Acid Sequence; Calcium; CD3 Complex; Cross-Linking Reagents; Cyclic GMP; Cytoplasm; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Glutathione Transferase; Humans; Inflammation; Isoenzymes; Jurkat Cells; L-Selectin; Lymphocytes; Mass Spectrometry; Molecular Sequence Data; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-theta; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine | 2004 |
Proteolysis of macrophage inflammatory protein-1alpha isoforms LD78beta and LD78alpha by neutrophil-derived serine proteases.
Topics: Amino Acid Sequence; Cathepsin G; Cathepsins; Chemokine CCL3; Chemokine CCL4; Chemokines; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Inflammation; Macrophage Inflammatory Proteins; Mass Spectrometry; Molecular Sequence Data; Myeloblastin; Neutrophils; Pancreatic Elastase; Peptides; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Time Factors | 2005 |
Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I.
Topics: Acrolein; Adenosine Triphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Apolipoprotein A-I; Arteries; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Blotting, Western; Cholesterol; Chromatography, Liquid; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Inflammation; Lipid Peroxidation; Lipoproteins, HDL; Lysine; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Peptides; Peroxidase; Phospholipids; Protein Structure, Secondary; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Threonine; Time Factors | 2005 |
Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II.
Topics: Atherosclerosis; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catalysis; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Epidermal Growth Factor; ErbB Receptors; Humans; Inflammation; Models, Biological; Mutation; Nitric Oxide; Nitric Oxide Synthase Type III; Peptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Receptor, PAR-1; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; src-Family Kinases; Threonine; Thrombin; Thrombomodulin; Time Factors; Tyrosine; Umbilical Veins | 2005 |
Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A.
Topics: Active Transport, Cell Nucleus; Adenosine Triphosphate; Alkenes; Animals; B-Lymphocytes; Catalysis; Cell Line; Chromatography, Liquid; Cytoplasm; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gene Deletion; Humans; I-kappa B Kinase; Immunoblotting; Immunoprecipitation; Inflammation; Jurkat Cells; Mice; Mice, Inbred C57BL; Mutation; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Polyenes; Protein Phosphatase 2; Pyrones; Sepharose; Serine; Signal Transduction; Spleen; Threonine; Time Factors; Transfection; Tumor Necrosis Factor-alpha | 2005 |
The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.
Topics: Amino Acid Sequence; Animals; Brain; Circular Dichroism; Codon; Crystallography, X-Ray; Evolution, Molecular; Humans; Inflammation; Kinetics; Leukocyte Elastase; Leukocytes; Ligands; Likelihood Functions; Mice; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Phylogeny; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Salts; Sequence Homology, Amino Acid; Serpins; Temperature; Threonine; Time Factors; Trypsin | 2005 |
Nitric oxide regulates prolidase activity by serine/threonine phosphorylation.
Topics: Animals; Blotting, Western; Cyclic GMP; Dipeptidases; DNA, Complementary; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Immunoprecipitation; Inflammation; Matrix Metalloproteinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Pathologic; NIH 3T3 Cells; Nitric Oxide; Nitric Oxide Synthase Type II; Peptides; Phosphorylation; Plasmids; Serine; Signal Transduction; Thiourea; Threonine; Time Factors; Transfection; Wound Healing | 2005 |
The ADP-stimulated NADPH oxidase activates the ASK-1/MKK4/JNK pathway in alveolar macrophages.
Topics: Adenine; Adenosine Diphosphate; Animals; Cell Line; Enzyme Activation; Inflammation; Macrophages, Alveolar; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 4; MAP Kinase Kinase Kinase 5; NADPH Oxidases; Phosphorylation; Rats; Signal Transduction; Threonine | 2006 |
Extracellular signal-regulated kinase-2 phosphorylates RORalpha4 in vitro.
Topics: Amino Acid Sequence; Circadian Rhythm; Cloning, Molecular; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; In Vitro Techniques; Inflammation; Leukocytes; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Mutation; Nuclear Receptor Subfamily 1, Group F, Member 1; Phosphorylation; Receptors, Cytoplasmic and Nuclear; Threonine; Trans-Activators | 2007 |
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chlorocebus aethiops; Enzyme Activation; HeLa Cells; Humans; Inflammation; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Weight; Osmolar Concentration; Phosphorylation; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Sequence Deletion; Stress, Physiological; Subcellular Fractions; Substrate Specificity; Threonine; Transfection; Tumor Necrosis Factor-alpha; Tyrosine | 1995 |
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated
Topics: Acetaldehyde; Acrolein; Aldehydes; Amino Acids; Catalase; Chlorides; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Heme; Humans; Hydrogen Peroxide; Hydroxy Acids; Hypochlorous Acid; Inflammation; Lysine; Mass Spectrometry; Molecular Structure; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Serine; Threonine | 1997 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |