Compounds > threonine

threonine and Down Syndrome

threonine has been researched along with Down Syndrome in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Classen, J; Meijer, M; Saarloos, I; Sullivan, PF; Verhage, M1
Elkins, JM; Eswaran, J; Filippakopoulos, P; Gerber, SA; Kettenbach, AN; Knapp, S; Olsen, JV; Roos, AK; Savitsky, P; Soundararajan, M1
Becker, W; Florencio Ortiz, V; Pasqualon, T; Schumacher, J; Soppa, U; Tejedor, FJ1
Albac, C; Allinquant, B; Dorard, E; Gorisse-Hussonnois, L; Guihenneuc-Jouyaux, C; Potier, MC1
Han, SW; Henrique-Silva, F; Machado-Santelli, GM; Pfister, SC1
Arpino, C; Curatolo, P; Lucarelli, P; Palmarino, M; Piciullo, A; Saccucci, P; Verdecchia, M1
Ahn, YS; Cheon, YH; Cho, HJ; Chung, SH; Jeong, HK; Kim, IS; Lee, HW; Radnaabazar, C; Ryoo, SR; Song, WJ; Yoo, JJ1
Cho, HJ; Chung, SH; Jeong, HK; Kim, MJ; Kim, YS; Lee, HW; Radnaabazar, C; Ryoo, SR; Seo, H; Son, MY; Song, WJ1
Caserta, MT; Wyrwicz, AM; Yao, FS1

Other Studies

9 other study(ies) available for threonine and Down Syndrome

ArticleYear
A Munc18-1 mutant mimicking phosphorylation by Down Syndrome-related kinase Dyrk1a supports normal synaptic transmission and promotes recovery after intense activity.
    Scientific reports, 2020, 02-21, Volume: 10, Issue:1

    Topics: Animals; Cell Survival; Down Syndrome; Dyrk Kinases; HEK293 Cells; Humans; Mice; Munc18 Proteins; Mutation; Neurons; Open Reading Frames; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Synaptic Transmission; Threonine

2020
Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
    Structure (London, England : 1993), 2013, Jun-04, Volume: 21, Issue:6

    Topics: Amino Acid Sequence; Catalytic Domain; Down Syndrome; Dyrk Kinases; Enzyme Activation; Humans; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; Substrate Specificity; Threonine

2013
The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation.
    Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:13

    Topics: Animals; Brain; Cell Cycle; Cell Differentiation; Cell Line; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Down Syndrome; Dyrk Kinases; Humans; Mice, Inbred ICR; Neurogenesis; Neurons; Phosphorylation; Primary Cell Culture; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; Threonine

2014
Increases of SET level and translocation are correlated with tau hyperphosphorylation at ser202/thr205 in CA1 of Ts65Dn mice.
    Neurobiology of aging, 2016, Volume: 46

    Topics: Amyloid beta-Protein Precursor; Animals; Brain; CA1 Region, Hippocampal; Cytoplasm; Disease Models, Animal; DNA-Binding Proteins; Down Syndrome; Gene Expression; Histone Chaperones; Male; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; Oncogene Proteins; Phosphorylation; Protein Phosphatase 2; Protein Transport; Serine; Sirolimus; tau Proteins; Threonine

2016
Mutational analyses of the signals involved in the subcellular location of DSCR1.
    BMC cell biology, 2002, Sep-11, Volume: 3

    Topics: Amino Acid Motifs; Animals; Calcineurin; Calcineurin Inhibitors; Cell Line; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Kidney; Muscle Proteins; Mutagenesis, Site-Directed; Nuclear Proteins; Point Mutation; Proline; Protein Isoforms; Protein Sorting Signals; Serine; src Homology Domains; Tetradecanoylphorbol Acetate; Threonine

2002
Association between presenilin-1 -48C/T polymorphism and Down's syndrome.
    Neuroscience letters, 2004, Aug-26, Volume: 367, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Cysteine; Down Syndrome; Female; Gene Frequency; Genotype; Humans; Infant; Male; Membrane Proteins; Middle Aged; Polymorphism, Genetic; Presenilin-1; Promoter Regions, Genetic; Threonine

2004
DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
    The Journal of biological chemistry, 2007, Nov-30, Volume: 282, Issue:48

    Topics: Alzheimer Disease; Animals; Brain; Cell Line; DNA, Complementary; Down Syndrome; Dyrk Kinases; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Models, Biological; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Serine; tau Proteins; Threonine

2007
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
    Journal of neurochemistry, 2008, Volume: 104, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; Down Syndrome; Dyrk Kinases; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; PC12 Cells; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Threonine; Tyrosine

2008
In vitro 1H and 31P NMR spectroscopic evidence of multiple aberrant biochemical pathways in murine trisomy 16 brain development.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2000, Volume: 18, Issue:8

    Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Choline; Creatine; Disease Models, Animal; Down Syndrome; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phosphorus Isotopes; Protons; Taurine; Threonine

2000