threonine and Disease Models, Animal

Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Gliosis; Mice; Mice, Transgenic; Threonine; Transcription Factors

Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethanol; Glycine; Hypertension; Kidney; Male; Muscle, Smooth; Rats; Rats, Inbred WKY; Systole; Threonine

Topics: Amino Acids, Essential; Animals; Child, Preschool; Dietary Proteins; Disease Models, Animal; Humans; Kwashiorkor; Liver Circulation; Liver Diseases; Muscles; Nutrition Disorders; Osmolar Concentration; Polyribosomes; Protein Biosynthesis; Protein-Energy Malnutrition; RNA; RNA, Messenger; Threonine; Tryptophan

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Animals; Arginine; Calpain; Disease Models, Animal; Glycine; Heart Failure; HEK293 Cells; Humans; Male; Membrane Proteins; Mice; Muscle Proteins; Mutagenesis, Site-Directed; Myocytes, Cardiac; Proteolysis; Signal Transduction; Threonine; Transfection

Topics: Animals; Disease Models, Animal; Disks Large Homolog 4 Protein; Epileptic Syndromes; Female; Glucose; Male; Mice; Mice, Knockout; p21-Activated Kinases; Protein Serine-Threonine Kinases; Pyridones; Pyrimidines; Serine; Spasms, Infantile; Threonine

Topics: Animals; Arteries; Disease Models, Animal; Fatty Acids; Female; Humans; Insulin; Intestines; Liver; Metabolomics; Methionine; Obesity; Swine; Swine, Miniature; Threonine; Veins

Topics: Aging; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Humans; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Parkinson Disease; Proline; Threonine

Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Locomotion; MAP Kinase Signaling System; Mice; Mice, Transgenic; Phosphorylation; Threonine

Topics: Animals; Antioxidants; Brain Ischemia; Disease Models, Animal; Gene Expression Regulation; Immunoglobulin G; Melatonin; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Signal Transduction; Threonine

Topics: Adult; Animals; Back; Biopsy; Calcium; Capsaicin; Cell Line; Collagenases; Disease Models, Animal; Erythema; Female; Healthy Volunteers; Humans; Interleukin-6; Interleukin-8; Keratinocytes; Male; Mice; Mice, Hairless; Peptides; Phosphorylation; Skin; Skin Aging; Threonine; TRPV Cation Channels; Tumor Necrosis Factor-alpha; Ultraviolet Rays

Topics: Animals; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Female; Gene Expression Regulation; Helicobacter Infections; Helicobacter pylori; Hippocampus; Maze Learning; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Stomach; tau Proteins; Threonine

Topics: Amyotrophic Lateral Sclerosis; Animals; Chronic Traumatic Encephalopathy; Disease Models, Animal; Female; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Spinal Cord; tau Proteins; Threonine

Topics: Alanine; alpha-Synuclein; Animals; Antiparkinson Agents; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Ginkgo biloba; Glutathione; Glutathione Peroxidase; Locomotion; Malondialdehyde; Mice; Mice, Transgenic; Muscle Strength; Mutation; Parkinson Disease; Plant Extracts; Superoxide Dismutase; Swimming; Threonine

Topics: Amino Acid Substitution; Animals; Arginine; Axons; Charcot-Marie-Tooth Disease; Disease Models, Animal; Drug Design; Glutamine; GTP Phosphohydrolases; Humans; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Oligopeptides; Phosphorylation; Protein Kinases; Sciatic Nerve; Small Molecule Libraries; Threonine

Topics: Alanine; alpha-Synuclein; Animals; Calcium-Binding Proteins; Disease Models, Animal; Endopeptidase K; Humans; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Mutation; Nerve Tissue Proteins; Neuroglia; Neurons; Parkinson Disease; Protein Aggregates; Protein Transport; Threonine; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase

Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Brain; Disease Models, Animal; Epitopes; Escherichia coli; Female; HEK293 Cells; Humans; Immunohistochemistry; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice, Transgenic; Phosphorylation; Recombinant Proteins; tau Proteins; Tauopathies; Threonine

Topics: Amino Acids; Animals; Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Chromatography, Liquid; Chromatography, Thin Layer; Deoxycytidine; Disease Models, Animal; Drug Monitoring; Drug Stability; Gemcitabine; Humans; Magnetic Resonance Spectroscopy; Pancreatic Neoplasms; Prodrugs; Tandem Mass Spectrometry; Threonine; Xenograft Model Antitumor Assays

Topics: Acute Kidney Injury; Animals; Arginine; Cardiomegaly; Disease Models, Animal; Disease Progression; Down-Regulation; Enzyme Activation; Fibrosis; HSP90 Heat-Shock Proteins; Male; Myocardium; Natriuretic Peptide, Brain; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats, Wistar; Renal Insufficiency, Chronic; Threonine; Time Factors

Topics: Analysis of Variance; Animals; Animals, Newborn; bcl-2-Associated X Protein; Cell Count; Cell Nucleus; Disease Models, Animal; Embryo, Mammalian; Endoplasmic Reticulum; Female; Gene Expression Regulation, Developmental; Humans; Hypoxia-Ischemia, Brain; Male; Mitochondria; Neuroblastoma; Neurons; Phosphorylation; Pregnancy; Rats; Rats, Wistar; Subcellular Fractions; Threonine

Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Lung; Lung Diseases; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Polymorphism, Single Nucleotide; Pulmonary Surfactant-Associated Protein D; Threonine

Topics: Animals; Brain Ischemia; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nestin; Phosphorylation; Phosphotransferases; Reperfusion Injury; Stem Cells; Threonine

Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arginine; Cell Death; Disease Models, Animal; Dopamine; Female; Green Fluorescent Proteins; HEK293 Cells; Humans; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neurodegenerative Diseases; Rats; Rats, Wistar; Substantia Nigra; Threonine; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Ubiquitin-Protein Ligases

Topics: Animals; Carrier Proteins; Cumulative Trauma Disorders; Disease Models, Animal; HEK293 Cells; Humans; Insulin-Like Growth Factor I; Male; MAP Kinase Signaling System; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Mitogen-Activated Protein Kinase 8; Multiprotein Complexes; Muscle, Skeletal; Phosphorylation; Protein Interaction Domains and Motifs; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rapamycin-Insensitive Companion of mTOR Protein; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Serine; Threonine; TOR Serine-Threonine Kinases

Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiac Pacing, Artificial; Cardiomegaly; Disease Models, Animal; Heart Ventricles; Hypertension; Male; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides; Threonine; Time Factors; Ventricular Fibrillation

Topics: Animals; Biomarkers; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Green Fluorescent Proteins; Intestine, Small; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Phosphorylation; Receptors, G-Protein-Coupled; Signal Transduction; Smad2 Protein; Smad3 Protein; Stem Cells; Threonine

Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Cell Differentiation; Disease Models, Animal; Dyrk Kinases; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Phenotype; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA, Small Interfering; Threonine

Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Cerebral Cortex; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factors; Male; Oxidative Stress; Phosphorylation; Protein Binding; Rats; Rats, Wistar; Reperfusion Injury; Threonine

Topics: Animals; Cell Membrane; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Female; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Polycystic Ovary Syndrome; Protein Processing, Post-Translational; Protein Transport; Random Allocation; Rats, Wistar; Serine; Sodium-Potassium-Exchanging ATPase; Threonine; Up-Regulation

Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Capsaicin; Disease Models, Animal; Glycerophospholipids; Glycine; Limonins; Male; Metabolomics; Prostatitis; Rats; Rats, Wistar; Serine; Threonine

Topics: Alanine; Animals; Calcium; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Humans; Hyperalgesia; Inflammation; Kinesins; Male; Mutation; Neurons; Peptides; Phosphorylation; Phosphotransferases; Rats; Rats, Sprague-Dawley; Threonine; TRPV Cation Channels

Topics: Alanine; alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Humans; Motor Activity; Oximes; Parkinson Disease; Protein Binding; Pyridines; Radioisotopes; Radionuclide Imaging; Rats; Rats, Transgenic; Receptors, Metabotropic Glutamate; Threonine; Time Factors

Topics: Adipose Tissue, Brown; Adiposity; Animals; Diet, High-Fat; Disease Models, Animal; Genetic Predisposition to Disease; Inflammation Mediators; Insulin Resistance; Intra-Abdominal Fat; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Panniculitis; Phenotype; Phosphorylation; Serine; Signal Transduction; Threonine

Topics: Age Factors; Aging; Alanine; Alzheimer Disease; Animals; Astrocytes; Cognition Disorders; Cytokines; Dendritic Spines; Disease Models, Animal; Encephalitis; Female; Humans; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Pneumothorax; RNA, Untranslated; tau Proteins; Threonine

Topics: Amino Acid Substitution; Animals; DEAD Box Protein 58; Disease Models, Animal; DNA Mutational Analysis; Host-Pathogen Interactions; Immune Evasion; Influenza A Virus, H1N1 Subtype; Mass Spectrometry; Mice; Nucleocapsid Proteins; Orthomyxoviridae Infections; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Receptors, Immunologic; RNA-Binding Proteins; Threonine; Viral Core Proteins; Viral Nonstructural Proteins; Virulence; Virus Replication

Topics: Amyloid beta-Protein Precursor; Animals; Brain; CA1 Region, Hippocampal; Cytoplasm; Disease Models, Animal; DNA-Binding Proteins; Down Syndrome; Gene Expression; Histone Chaperones; Male; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; Oncogene Proteins; Phosphorylation; Protein Phosphatase 2; Protein Transport; Serine; Sirolimus; tau Proteins; Threonine

Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Ischemia; Lithium Chloride; Male; Phosphorylation; Pilocarpine; Prosencephalon; Rats; Rats, Wistar; Status Epilepticus; Synaptosomes; Threonine

Topics: Amino Acid Substitution; Animals; Animals, Genetically Modified; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; DNA Primers; Female; Insulin-Secreting Cells; Mice; Mice, Inbred Strains; Threonine

Topics: Alanine; Animals; Animals, Newborn; Calbindins; Calcium Channels, N-Type; Cells, Cultured; Cysteine; Disease Models, Animal; Glycine; Green Fluorescent Proteins; Ion Channel Gating; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Models, Molecular; Mutation; Nervous System Diseases; Patch-Clamp Techniques; Purkinje Cells; S100 Calcium Binding Protein G; Silver Staining; Threonine; Tyrosine 3-Monooxygenase

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Butyrates; Cell Line, Transformed; Cognition Disorders; Disease Models, Animal; Enzyme Inhibitors; Humans; Immunoprecipitation; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Niacinamide; Peptide Fragments; Phosphorylation; Presenilin-1; Sirtuins; tau Proteins; Threonine; Time Factors; Transfection; Tubulin; Vitamin B Complex

Topics: Animals; Apamin; Blood Pressure; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Potassium Channels, Calcium-Activated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Serine; Threonine

Topics: Amino Acid Substitution; Animals; Antigens, Differentiation; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Diabetic Nephropathies; Disease Models, Animal; Kidney; Macrophages; Male; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Osteopontin; RNA, Messenger; Threonine

Topics: Age Factors; Animals; Anti-Bacterial Agents; Apoptosis; CD11b Antigen; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Enzyme Inhibitors; In Situ Nick-End Labeling; Laminin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Muscle, Skeletal; Muscular Dystrophy, Animal; Mutation; Phosphorylation; Proto-Oncogene Proteins c-akt; Staurosporine; Survival Analysis; Threonine

Topics: Animals; CD8 Antigens; Crystallography, X-Ray; Disease Models, Animal; Humans; Hydrogen Bonding; Macaca mulatta; Mice; Protein Conformation; Protein Multimerization; Threonine

Topics: Alanine; alpha-Synuclein; Animals; Disease Models, Animal; Humans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Norepinephrine; Parkinson Disease; Threonine

Topics: Adenosine Triphosphate; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Dietary Proteins; Disease Models, Animal; Eating; Energy Metabolism; Flavin-Adenine Dinucleotide; Liver; Male; Mitochondria, Heart; Mitochondria, Liver; Myocardium; NAD; Oxidative Phosphorylation; Protein Deficiency; Rats; Rats, Sprague-Dawley; Threonine; Time Factors

Topics: Analysis of Variance; Animals; Anisomycin; Cocaine; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Green Fluorescent Proteins; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Motor Activity; Narcotics; Point Mutation; Protein Synthesis Inhibitors; Raclopride; Receptors, Dopamine D1; Substance-Related Disorders; Threonine; Time Factors

Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebellum; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperammonemia; In Vitro Techniques; Male; Microdialysis; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Phosphorylation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Statistics, Nonparametric; Subcellular Fractions; Threonine

Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cloning, Molecular; Disease Models, Animal; Growth Hormone; Humans; Mutation; Neurons; Neurosecretion; Neurotransmitter Agents; PC12 Cells; Phosphorylation; Phosphotransferases; Rats; Threonine; Transfection; Transgenes

Topics: Amino Acid Sequence; Animals; Biomarkers; Cell Compartmentation; Cell Line, Transformed; Cell Membrane; Cell Polarity; Disease Models, Animal; Dogs; Epithelial Cells; ErbB Receptors; Humans; Mice; Models, Biological; Molecular Sequence Data; Mutation; Polycystic Kidney, Autosomal Recessive; Protein Transport; rab GTP-Binding Proteins; Signal Transduction; Sus scrofa; Threonine

Topics: alpha-Crystallin B Chain; Animals; Animals, Newborn; Apoptosis; Cell Survival; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Hydrogen Peroxide; Ischemic Preconditioning, Myocardial; Mice; Mice, Transgenic; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oligopeptides; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase C; Protein Transport; Rats; Rats, Wistar; Signal Transduction; Threonine; Time Factors

Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Evoked Potentials; Fluorescent Antibody Technique; Humans; Mice; Mice, Transgenic; Microscopy, Confocal; Motor Neurons; Mutation; Neuronal Plasticity; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxide Dismutase-1; Threonine

Topics: Absorption; Animals; Blood Pressure; Cell Membrane; Disease Models, Animal; Furosemide; Hypertension; Loop of Henle; Male; Oxygen Consumption; Phosphorylation; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Threonine; Time Factors

Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Humans; Mice; Neoplasm Metastasis; Pheochromocytoma; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 2; Serine; Temozolomide; Threonine

Topics: Animals; Aorta; Atherosclerosis; Biological Transport; Disease Models, Animal; Foam Cells; Focal Adhesion Kinase 1; Integrins; Male; NF-kappa B; Panax notoginseng; Phosphorylation; Phytotherapy; Plant Extracts; Plaque, Atherosclerotic; Rats; Rats, Wistar; Saponins; Threonine; Zymosan

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Brain; Cell Cycle Proteins; Centrosome; Disease Models, Animal; Humans; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitosis; Phosphorylation; Plaque, Amyloid; Protein Processing, Post-Translational; RNA, Small Interfering; Threonine; Transfection

Topics: Animals; Antibodies, Antinuclear; Boronic Acids; Cytokines; Disease Models, Animal; Drug Administration Routes; Female; Kidney; Lupus Erythematosus, Systemic; Lupus Nephritis; Mice; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Spleen; Threonine

Topics: Animals; Antiemetics; Biophysical Phenomena; Biotinylation; Body Weight; Carbamazepine; Cells, Cultured; Chromosome Mapping; Disease Models, Animal; DNA Mutational Analysis; Electric Stimulation; Electroencephalography; Electromyography; Epilepsy; Ethylnitrosourea; Gene Transfer Techniques; Humans; Isaacs Syndrome; Kv1.1 Potassium Channel; Male; Membrane Potentials; Mice; Models, Molecular; Mutagenesis; Mutagens; Mutation, Missense; Myokymia; Oocytes; Patch-Clamp Techniques; Protein Transport; Psychomotor Performance; Rats; Rats, Inbred F344; Rats, Mutant Strains; Sequence Analysis; Serine; Survival Analysis; Swimming; Threonine; Time Factors; Xenopus

Topics: Animals; Antigens, Surface; Brain Edema; Cell Count; Chemokine CXCL2; Disease Models, Animal; Endothelial Cells; Fluoresceins; Gene Expression Regulation; Injections, Intraventricular; Male; Neutrophil Infiltration; NF-kappa B; Organic Chemicals; Phosphorylation; Pilocarpine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Status Epilepticus; Threonine; Tumor Necrosis Factor-alpha

Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Disease Models, Animal; Drug Tolerance; Hyperalgesia; Hypersensitivity; Inflammation; Male; Morphine; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Threonine

Topics: Action Potentials; Amino Acid Sequence; Amino Acids; Animals; Capsaicin; Chromosome Mapping; Chromosomes, Mammalian; Dendrites; Disease Models, Animal; Exons; Eye Diseases, Hereditary; Genetic Diseases, X-Linked; Heterozygote; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation, Missense; Myopia; Night Blindness; Point Mutation; Retina; Retinal Bipolar Cells; Sequence Analysis, DNA; Threonine; TRPM Cation Channels; Xanthenes

Topics: Animals; Animals, Newborn; Biotinylation; Calcium-Binding Proteins; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Dark Adaptation; Dendrites; Disease Models, Animal; Electric Stimulation; Electroporation; Enzyme Inhibitors; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Luminescent Proteins; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Muscarinic Agonists; Mutation; Neural Cell Adhesion Molecules; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Photons; Pilocarpine; Plant Lectins; Potassium Chloride; Pregnancy; Pyridinium Compounds; Quaternary Ammonium Compounds; Red Fluorescent Protein; Signal Transduction; Status Epilepticus; Synaptic Transmission; Threonine; Transfection; Vesicular Glutamate Transport Protein 1

Topics: Animals; Benzopyrans; CD4-Positive T-Lymphocytes; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Disease Models, Animal; Female; Fibroblasts; Focal Adhesion Kinase 1; Humans; In Vitro Techniques; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Stress, Mechanical; Threonine

Topics: Administration, Cutaneous; Animals; Bacitracin; Cysteine; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Glycine; Inflammation; Medicine, African Traditional; Neomycin; Nigeria; Oils, Volatile; Ointments; Phytotherapy; Plant Oils; Rabbits; Random Allocation; Threonine; Wound Healing; Wounds and Injuries

Topics: Age Factors; Alanine; alpha-Synuclein; Animals; Behavior, Animal; Blotting, Western; Disease Models, Animal; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Motor Activity; Mutation; Nerve Tissue Proteins; Parkinson Disease; Phenylenediamines; RNA; Sciatic Nerve; Spinal Cord; Synucleins; Threonine; Wallerian Degeneration

Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Chromosome Breakage; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cytogenetic Analysis; Disease Models, Animal; Female; Genomic Instability; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; ras Proteins; Threonine; Translocation, Genetic; Tumor Suppressor Protein p53; Ubiquitin

Topics: Aging; Alleles; Animals; Antibodies, Monoclonal; Asparagine; Blotting, Northern; Blotting, Southern; Blotting, Western; Brain; Carbohydrates; Cell Membrane; Cells, Cultured; Detergents; Disease Models, Animal; DNA; Embryo, Mammalian; Endopeptidase K; Endoplasmic Reticulum; Female; Genetic Vectors; Genotype; Glycoproteins; Glycosylation; Golgi Apparatus; Homozygote; Immunohistochemistry; Male; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Mice, Transgenic; Microscopy, Confocal; Models, Genetic; Mutation; Neurons; Phenotype; Polymerase Chain Reaction; Polysaccharides; Prions; Recombination, Genetic; RNA; RNA, Messenger; Scrapie; Solubility; Stem Cells; Threonine; Time Factors; Type C Phospholipases

Topics: Alcoholic Intoxication; Animals; Binding Sites; Burns; Cytokines; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Ethanol; Immune Tolerance; Lymph Nodes; Male; MAP Kinase Signaling System; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Threonine; Tyrosine

Topics: 3T3 Cells; Alleles; Amino Acid Substitution; Animals; Cells, Cultured; Crosses, Genetic; Disease Models, Animal; Embryonic Stem Cells; Female; Magnetic Resonance Spectroscopy; Methionine; Mice; Mice, Inbred C57BL; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-CH Group Donors; Phenotype; Simvastatin; Smith-Lemli-Opitz Syndrome; Threonine

Topics: Animals; Brain; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Convulsants; Disease Models, Animal; Enzyme Activation; Epilepsy; Kainic Acid; Male; Membrane Potentials; Neurons; Phosphorylation; Rats; Rats, Wistar; Recovery of Function; Solubility; Status Epilepticus; Threonine

Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Disease Models, Animal; Drosophila; Gene Expression Regulation, Enzymologic; Humans; Longevity; Metabolic Diseases; Metabolism, Inborn Errors; Molecular Sequence Data; Mutation, Missense; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Threonine; Transgenes; Triose-Phosphate Isomerase

Topics: Aging; Animals; Cell Fractionation; Cholic Acids; Detergents; Disease Models, Animal; Membrane Microdomains; Mice; Mice, Inbred Strains; Mice, Transgenic; Multiple Sclerosis; Myelin Basic Protein; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Severity of Illness Index; Silver Staining; Subcellular Fractions; Threonine

Topics: Angelman Syndrome; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Disease Models, Animal; Mice; Phosphorylation; Threonine; Ubiquitin-Protein Ligases

Topics: Animals; Blotting, Western; Brain; Disease Models, Animal; Hypoxia, Brain; Immunohistochemistry; Ischemic Preconditioning; Male; Mice; Mice, Inbred BALB C; Neurogranin; Neurons; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Threonine; Time Factors

Topics: Animals; Animals, Genetically Modified; Ataxin-7; Cell Death; Cells, Cultured; Disease Models, Animal; Drosophila; Dyskinesias; Glutamine; Humans; Intranuclear Inclusion Bodies; Longevity; Male; Mutation; Nerve Tissue Proteins; Neurons; Peptides; Phenotype; Rats; Spinocerebellar Ataxias; Threonine

Topics: Achondroplasia; Animals; Apoptosis; Cell Proliferation; Chondrocytes; Disease Models, Animal; Dwarfism; Endoplasmic Reticulum; Extracellular Matrix Proteins; Female; Glycoproteins; Male; Matrilin Proteins; Methionine; Mice; Mice, Knockout; Mutation; Osteochondrodysplasias; Phenotype; Protein Structure, Tertiary; Threonine

Topics: Angiotensin II; Animals; Antibodies; Carotid Artery Diseases; Catheterization; Cells, Cultured; Disease Models, Animal; Humans; Lymphokines; Muscle, Smooth, Vascular; Mutagenesis; Phosphorylation; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein Kinase C; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Serine; Sp1 Transcription Factor; Spectrometry, Mass, Electrospray Ionization; Threonine; Transcription, Genetic; Vasoconstrictor Agents; Zinc Fingers

Topics: Animals; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Parkinson Disease; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Threonine; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

Topics: Animals; Disease Models, Animal; Humans; Isoleucine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Microscopy, Electron, Transmission; Muscle Proteins; Muscle, Skeletal; Muscular Dystrophies, Limb-Girdle; Mutation; Threonine

Topics: 1-Carboxyglutamic Acid; Animals; Calciphylaxis; Dihydrotachysterol; Disease Models, Animal; Female; Glutamates; Ovalbumin; Phosphoserine; Phosphothreonine; Rats; Serine; Skin; Skin Diseases; Threonine

Topics: Animals; Caseins; Diet, Protein-Restricted; Disease Models, Animal; Food, Fortified; Hyperlipidemias; Hypolipidemic Agents; Male; Methionine; Microsomes, Liver; Nephritis; Proteinuria; Rats; Rats, Wistar; Threonine

Topics: Animals; Aspartic Acid; Brain Ischemia; Dialysis; Disease Models, Animal; Glutamic Acid; Hematoma, Subdural; Male; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Threonine

Topics: Animals; Anorexia; Chickens; Diet; Disease Models, Animal; Eating; Escherichia coli; Female; Lipopolysaccharides; Lysine; Proteins; Threonine; Weight Gain

Topics: Amino Acid Sequence; Animals; Blotting, Northern; Chloride Channels; Disease Models, Animal; DNA Primers; Dogs; Electrophysiology; Genes, Recessive; Homozygote; Methionine; Molecular Sequence Data; Muscle, Skeletal; Mutation, Missense; Myotonia Congenita; Pedigree; Polymerase Chain Reaction; Recombinant Proteins; Sequence Homology, Amino Acid; Threonine

Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Choline; Creatine; Disease Models, Animal; Down Syndrome; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phosphorus Isotopes; Protons; Taurine; Threonine

Topics: alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Dihydro-beta-Erythroidine; Disease Models, Animal; Electrophysiology; Female; Ganglionic Stimulants; Heterozygote; Hippocampus; Lysine; Male; Mice; Mice, Inbred C57BL; Neuroanatomy; Nicotine; Phenotype; Receptors, Nicotinic; Seizures; Threonine

Topics: Actomyosin; Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Deficiency Diseases; Disease Models, Animal; DNA; Female; Glycogen; Kwashiorkor; Leucine; Lipid Metabolism; Liver; Mitochondria; Muscle Proteins; Myocardium; Myofibrils; Organ Size; Polyribosomes; Protein Biosynthesis; Rats; RNA; Threonine

Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Dactinomycin; Deficiency Diseases; Deoxycholic Acid; Diet; Disease Models, Animal; Female; Kwashiorkor; Leucine; Liver; Orotic Acid; Polyribosomes; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Ribosomal; Subcellular Fractions; Threonine

Topics: Alanine; Amino Acids; Animals; Disease Models, Animal; Glutamates; Phenylalanine; Proline; Rats; Threonine

Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Disease Models, Animal; Kwashiorkor; Leucine; Muscle Proteins; Rats; Threonine; Tritium