threonine has been researched along with Disease Exacerbation in 34 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 13 (38.24) | 29.6817 |
2010's | 13 (38.24) | 24.3611 |
2020's | 8 (23.53) | 2.80 |
Authors | Studies |
---|---|
Das, S; Grippo, PJ; Kumar, S; Nair, RS; Principe, DR; Rana, A; Rana, B; Singh, SK; Sinha, SC; Sondarva, G; Srivastava, P; Thatcher, GRJ; Viswakarma, N | 1 |
Bjerke, M; Bridel, C; De Deyn, PP; Engelborghs, S; Nagels, G; Niemantsverdriet, E; Rozemuller, A; Sieben, A; Somers, C; Struyfs, H; Teunissen, CE; Van Broeckhoven, C; Vermeiren, Y | 1 |
Banks, SJ; Brewer, JB; Edland, SD; Galasko, D; Reas, ET; Sundermann, EE; Tsiknia, AA | 1 |
Chatzipanagiotou, S; Constantinides, VC; Daskalaki, A; Gargalionis, AN; Kalligerou, F; Mamalaki, E; Ntanasi, E; Patas, K; Scarmeas, N; Yannakoulia, M | 1 |
Arellano-Gutiérrez, CV; Bolaños, J; Contis-Montes de Oca, A; Fragozo-Sandoval, F; López-Casamichana, M; López-Reyes, I; Padilla-Mendoza, JR; Quintas-Granados, LI; Reséndiz-Albor, AA; Reyes-Hernández, OD; Rodríguez, MA | 1 |
Cullen, N; Dage, JL; Hansson, O; Janelidze, S; Mattsson-Carlgren, N; Mengel, D; Palmqvist, S; Stomrud, E; Strandberg, O; Svenningsson, AL; Walsh, DM | 1 |
Ashton, NJ; Blennow, K; Grothe, MJ; Karikari, TK; Moscoso, A; Rodriguez, JL; Schöll, M; Snellman, A; Suárez-Calvet, M; Zetterberg, H | 1 |
Chao, A; Chi, LM; Jung, SM; Lee, YS; Lin, CY; Tsai, CL; Tsai, CN | 1 |
Brooks, AJ; Chhabra, Y; Kragelund, BB; Meunier, FA; Nikolajsen, LF; Papadopulos, A; Smith, AG; Steinocher, H; Tunny, KA; Waters, MJ; Wong, HY | 1 |
Attems, J; Daum, G; Flunkert, S; Hoeller, C; Hutter-Paier, B; Kerschbaumer, B; Loeffler, T; Neddens, J; Niederkofler, V; Temmel, M | 1 |
Amador-Martínez, I; Barrera-Chimal, J; Bobadilla, NA; Cortés-González, C; Pérez-Villalva, R; Uribe, N | 1 |
Sang, B; Sun, J; Wei, Y; Xu, Z; Yang, D | 1 |
Hua-Lei, L; Jing, C; Li, Z; Qian-Wei, X; Weng-Guang, L; You, W; Yu-Ping, Z | 1 |
Camidge, DR; Ching, KA; Christensen, JG; Clark, JW; Diamond, JR; Eckhardt, SG; Kanteti, R; Lira, ME; LoRusso, PM; Salgia, R; Schoenmakers, EF; Varella-Garcia, M; Wilner, K; Xu, LG | 1 |
Andreasen, N; Li, TQ; Li, X; Wahlund, LO; Westman, E; Wiberg, MK | 1 |
Barros, AS; Bom, AT; Bousquet, J; Carrola, J; Duarte, IF; Gil, AM; Gomes, J; Loureiro, CC; Rocha, SM | 1 |
Fujinaga, M; Furutsuka, K; Hashimoto, H; Hatori, A; Kawamura, K; Kumata, K; Nengaki, N; Shimoda, Y; Shiomi, S; Takei, M; Wakizaka, H; Xie, L; Yamasaki, T; Yui, J; Zhang, MR | 1 |
Dong, ZY; Gao, HF; Gou, LY; Li, AN; Liu, SY; Lou, NN; Su, J; Wu, YL; Xie, Z; Xu, CR; Yan, HH; Yang, JJ; Zhang, XC; Zhong, WZ; Zhou, Q | 1 |
Chen, H; Chen, L; Dong, Z; He, Z; Huang, GL; Li, B; Li, H; Li, T; Liao, D; Liu, W; Lu, Y; Uchida, T; Wang, J; Ye, C; Zhu, Z; Zou, Y | 1 |
Sakurai, H | 1 |
Hiraga, K; Ichsan, AM; Ishii, Y; Kato, I; Nakada, S; Okamoto, H; Oya, T; Sasahara, M; Shimada, Y; Suzuki, H; Takasawa, K; Takasawa, S; Tobe, K | 1 |
Bini, P; Costa, A; Franciotta, D; Moglia, A; Ravaglia, S; Sinforiani, E; Tosca, P; Zardini, E | 1 |
Aisen, PS; Blennow, K; Clark, CM; Dean, R; Knapik-Czajka, M; Lee, VM; Lewczuk, P; Petersen, RC; Potter, W; Shaw, LM; Siemers, E; Simon, A; Soares, H; Trojanowski, JQ; Vanderstichele, H | 1 |
Blankenstein, MA; Bouwman, FH; Klein, M; Scheltens, P; van der Flier, WM; van der Vlies, AE; Verwey, NA | 1 |
Barkhof, F; Barnes, J; Blankenstein, MA; Fox, NC; Henneman, WJ; Klein, M; Scheltens, P; Sluimer, IC; van der Flier, WM; Verwey, NA; Vrenken, H | 1 |
Buck, M; Chojkier, M | 1 |
Andreasen, N; Arai, H; Blennow, K; Buerger, K; Davies, P; DeBernardis, J; Engel, R; Hampel, H; Heun, R; Hofmann-Kiefer, K; Kerkman, D; McCulloch, C; Moeller, H; Ptok, U; Teipel, SJ; Zinkowski, R | 1 |
Gallick, GE; Kim, LS; Minard, ME; Price, JE | 1 |
Hemmer, B; Kolb-Mäurer, A; Kroner, A; Kruse, N; Mäurer, M; Rieckmann, P; Toyka, KV; Vogel, F | 1 |
Abrahamsson, PA; Ahlgren, G; Gadaleanu, V; Giwercman, A; Giwercman, YL | 1 |
Bergh, S; de Groot, JF; Koul, D; Liu, TJ; Lu, Y; Mills, GB; Shen, R; Yung, WK | 1 |
Almgren, P; Berglund, G; Fava, C; Guidi, GC; Melander, O; Montagnana, M; Rosberg, L | 1 |
Mantuano, E; Veneziano, L | 1 |
Buerger, K; Davies, P; Hampel, H; Kohnken, R; Moeller, HJ; Rapoport, SI; Teipel, SJ; Zinkowski, R | 1 |
3 review(s) available for threonine and Disease Exacerbation
Article | Year |
---|---|
MTHFR C677T and A1298C polymorphisms were associated with bladder cancer risk and disease progression: a meta-analysis.
Topics: Alanine; Amino Acid Substitution; Carcinoma; Case-Control Studies; Cysteine; Disease Progression; Genetic Predisposition to Disease; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Urinary Bladder Neoplasms | 2013 |
Non-canonical Activation of Receptor Tyrosine Kinases in Cancer Progression.
Topics: Antineoplastic Agents; Cell Movement; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Phosphorylation; Receptor Protein-Tyrosine Kinases; Receptor, EphA2; Receptor, ErbB-2; Serine; Threonine | 2017 |
The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression.
Topics: Animals; Apoptosis; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Disease Progression; GTP Phosphohydrolases; Guanine Nucleotide Exchange Factors; Humans; Mice; Neoplasm Invasiveness; Neoplasms; Phosphorylation; Proteins; rho GTP-Binding Proteins; Signal Transduction; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Threonine | 2004 |
31 other study(ies) available for threonine and Disease Exacerbation
Article | Year |
---|---|
MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinase Kinase Kinase 11; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Threonine; Up-Regulation | 2021 |
Associating Alzheimer's disease pathology with its cerebrospinal fluid biomarkers.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Biomarkers; Disease Progression; Female; Humans; Male; Peptide Fragments; Plaque, Amyloid; tau Proteins; Threonine | 2022 |
Sex differences in plasma p-tau181 associations with Alzheimer's disease biomarkers, cognitive decline, and clinical progression.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognitive Dysfunction; Disease Progression; Female; Glucose; Humans; Male; Sex Characteristics; tau Proteins; Threonine | 2022 |
Initial Data and a Clinical Diagnosis Transition for the Aiginition Longitudinal Biomarker Investigation of Neurodegeneration (ALBION) Study.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Disease Progression; Humans; tau Proteins; Threonine | 2022 |
Protein Phosphorylation in Serine Residues Correlates with Progression from Precancerous Lesions to Cervical Cancer in Mexican Patients.
Topics: Adult; Cervix Uteri; Clusterin; Disease Progression; Female; Heat-Shock Proteins; Humans; Keratin-19; Keratin-8; Mexico; Middle Aged; Molecular Chaperones; Papillomavirus Infections; Phosphorylation; Precancerous Conditions; Proteomics; Serine; Squamous Intraepithelial Lesions of the Cervix; Threonine; Uterine Cervical Neoplasms; Young Adult | 2020 |
Longitudinal plasma p-tau217 is increased in early stages of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognitive Dysfunction; Disease Progression; Female; Humans; Longitudinal Studies; Male; Mental Status and Dementia Tests; Middle Aged; Neuropsychological Tests; Phosphorylation; Prospective Studies; tau Proteins; Threonine | 2020 |
Time course of phosphorylated-tau181 in blood across the Alzheimer's disease spectrum.
Topics: Alzheimer Disease; Biomarkers; Brain; Disease Progression; Humans; Longitudinal Studies; Phosphorylation; Positron-Emission Tomography; Prospective Studies; tau Proteins; Threonine | 2021 |
Glycogen synthase kinase-3 beta (GSK3β)-mediated phosphorylation of ETS1 promotes progression of ovarian carcinoma.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Glycogen Synthase Kinase 3 beta; Humans; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Models, Biological; Mutation; Neoplasm Staging; Ovarian Neoplasms; Phosphorylation; Protein Binding; Protein Stability; Proto-Oncogene Protein c-ets-1; Serine; Substrate Specificity; Threonine | 2021 |
A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Cohort Studies; Computational Biology; Disease Progression; DNA Mutational Analysis; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lung; Lung Neoplasms; Magnetic Resonance Spectroscopy; Male; Mice; Phosphorylation; Polymorphism, Single Nucleotide; Proline; Protein Binding; Protein Domains; Proteolysis; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Threonine; Ubiquitin-Protein Ligases; Ubiquitination | 2018 |
Phosphorylation of different tau sites during progression of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Disease Progression; Female; Humans; Male; Middle Aged; Phosphorylation; Psychiatric Status Rating Scales; Serine; Statistics, Nonparametric; tau Proteins; Threonine; Tyrosine | 2018 |
Reduced endothelial nitric oxide synthase activation contributes to cardiovascular injury during chronic kidney disease progression.
Topics: Acute Kidney Injury; Animals; Arginine; Cardiomegaly; Disease Models, Animal; Disease Progression; Down-Regulation; Enzyme Activation; Fibrosis; HSP90 Heat-Shock Proteins; Male; Myocardium; Natriuretic Peptide, Brain; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats, Wistar; Renal Insufficiency, Chronic; Threonine; Time Factors | 2019 |
Ras-AKT signaling represses the phosphorylation of histone H1.5 at threonine 10 via GSK3 to promote the progression of glioma.
Topics: Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; Glioma; Glycogen Synthase Kinase 3; Histones; Humans; Phosphorylation; Proteolysis; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; ras Proteins; Signal Transduction; Threonine; Transcription, Genetic | 2019 |
Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
Topics: Antineoplastic Agents; Biopsy; Carcinoma, Renal Cell; Disease Progression; Drug Resistance, Neoplasm; Heterozygote; Humans; In Situ Hybridization, Fluorescence; Kidney Neoplasms; Male; Methionine; Middle Aged; Point Mutation; Proto-Oncogene Proteins c-met; Pyrazines; Receptor Protein-Tyrosine Kinases; Sequence Analysis, DNA; Threonine; Treatment Failure; Triazoles | 2013 |
The association between biomarkers in cerebrospinal fluid and structural changes in the brain in patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Brain; Cognitive Dysfunction; Cross-Sectional Studies; Diffusion Tensor Imaging; Disease Progression; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments; Phosphorylation; Predictive Value of Tests; Sensitivity and Specificity; Severity of Illness Index; tau Proteins; Threonine | 2014 |
Urinary metabolomic changes as a predictive biomarker of asthma exacerbation.
Topics: Adult; Aged; Asthma; Biomarkers; Carnitine; Cohort Studies; Disease Progression; Female; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylamines; Middle Aged; Oxidative Stress; Pilot Projects; Prospective Studies; Threonine | 2014 |
Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.
Topics: Alanine; alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Humans; Motor Activity; Oximes; Parkinson Disease; Protein Binding; Pyridines; Radioisotopes; Radionuclide Imaging; Rats; Rats, Transgenic; Receptors, Metabotropic Glutamate; Threonine; Time Factors | 2016 |
The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer.
Topics: Adult; Aged; Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation, Missense; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Threonine; Up-Regulation; Young Adult | 2016 |
The protein level and transcription activity of activating transcription factor 1 is regulated by prolyl isomerase Pin1 in nasopharyngeal carcinoma progression.
Topics: Activating Transcription Factor 1; Animals; Carcinogenesis; Carcinoma; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mice, Inbred BALB C; Mice, Nude; Mutation; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Phosphorylation; Protein Binding; Protein Stability; Threonine; Transcription, Genetic | 2016 |
A novel model of insulin-dependent diabetes with renal and retinal lesions by transgenic expression of CaMKIIalpha (Thr286Asp) in pancreatic beta-cells.
Topics: Amino Acid Substitution; Animals; Animals, Genetically Modified; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; DNA Primers; Female; Insulin-Secreting Cells; Mice; Mice, Inbred Strains; Threonine | 2008 |
Cerebrospinal fluid levels of tau phosphorylated at threonine 181 in patients with Alzheimer's disease and vascular dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Brain; Catalytic Domain; Cognition Disorders; Dementia, Vascular; Disease Progression; Female; Humans; Male; Middle Aged; Neurons; Neuropsychological Tests; Phosphorylation; tau Proteins; Threonine | 2008 |
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Area Under Curve; Biomarkers; Cognition Disorders; Cohort Studies; Diagnostic Imaging; Disease Progression; Female; Humans; Male; Middle Aged; Peptide Fragments; Phosphorylation; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Statistics, Nonparametric; tau Proteins; Threonine | 2009 |
CSF biomarkers in relationship to cognitive profiles in Alzheimer disease.
Topics: Aged; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; Cognition Disorders; Disability Evaluation; Disease Progression; Female; Humans; Male; Memory Disorders; Mental Processes; Middle Aged; Neuropsychological Tests; Peptide Fragments; Phosphorylation; Severity of Illness Index; tau Proteins; Threonine; Up-Regulation | 2009 |
Baseline CSF p-tau levels independently predict progression of hippocampal atrophy in Alzheimer disease.
Topics: Aged; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Atrophy; Biomarkers; Disease Progression; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Phosphorylation; Predictive Value of Tests; Sensitivity and Specificity; Severity of Illness Index; tau Proteins; Threonine | 2009 |
C/EBPβ-Thr217 phosphorylation signaling contributes to the development of lung injury and fibrosis in mice.
Topics: Animals; Bleomycin; Caspase 8; CCAAT-Enhancer-Binding Protein-beta; Cell Death; Disease Progression; Female; Gene Expression Regulation, Enzymologic; Humans; Lung; Lung Injury; Male; Mice; Mice, Transgenic; Myofibroblasts; Peptide Fragments; Phosphorylation; Pulmonary Fibrosis; Ribosomal Protein S6 Kinases; Signal Transduction; Threonine | 2011 |
CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Biomarkers; Cognition Disorders; Disease Progression; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Phosphorylation; Predictive Value of Tests; Regression Analysis; Risk Factors; tau Proteins; Threonine | 2002 |
Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Cells, Cultured; Cytokines; Disease Progression; Germany; Glycine; Humans; Isoleucine; Membrane Glycoproteins; Middle Aged; Multiple Sclerosis; Polymorphism, Genetic; Receptors, Cell Surface; T-Lymphocytes, Regulatory; Threonine; Toll-Like Receptor 4; Toll-Like Receptors | 2005 |
The 5alpha-reductase type II A49T and V89L high-activity allelic variants are more common in men with prostate cancer compared with the general population.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Alanine; Alleles; Arginine; Biomarkers, Tumor; Case-Control Studies; Dihydrotestosterone; Disease Progression; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Luteinizing Hormone; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Risk Factors; Sex Hormone-Binding Globulin; Sweden; Terminal Repeat Sequences; Testosterone; Threonine; Valine | 2005 |
Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma.
Topics: Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Fibronectins; G2 Phase; Glioblastoma; Glioma; Humans; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Vascular Endothelial Growth Factor A; Vitronectin | 2005 |
The functional variant of the CLC-Kb channel T481S is not associated with blood pressure or hypertension in Swedes.
Topics: Adult; Blood Pressure; Chloride Channels; Cohort Studies; Cross-Sectional Studies; Disease Progression; Female; Gene Frequency; Genotype; Humans; Hypertension; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Prevalence; Serine; Sweden; Threonine; Time Factors; White People | 2007 |
Early onset progressive ataxia associated with the first CACNA1A mutation identified within the I-II loop.
Topics: Alanine; Ataxia; Calcium Channels; Disease Progression; Humans; Mutation; Protein Structure, Tertiary; Threonine | 2007 |
Tracking of Alzheimer's disease progression with cerebrospinal fluid tau protein phosphorylated at threonine 231.
Topics: Aged; Alzheimer Disease; Disease Progression; Female; Humans; Male; Middle Aged; Phosphorylation; tau Proteins; Threonine | 2001 |