threonine and Diabetes Mellitus, Type 2

threonine has been researched along with Diabetes Mellitus, Type 2 in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (18.00)	18.2507
2000's	19 (38.00)	29.6817
2010's	17 (34.00)	24.3611
2020's	5 (10.00)	2.80

Authors

Authors	Studies
Huang, C; Lin, D; Lu, R; Zhang, Y; Zhou, L; Zou, H	1
Araki, E; Cai, W; Fukuda, K; Fukuda, T; Igata, M; Kahn, CR; Kondo, T; Okagawa, S; Okubo, Y; Otsuka, Y; Sakaguchi, M; Sakaguchi, N; Sato, Y; Tseng, YH; Yamagata, K; Yoshizawa, T	1
Guo, Z; Li, Y; Liang, Y; Liu, Y; Qu, L; Sun, G; Wang, H; Wang, Y; Zhang, C	1
Chen, Y; Ge, X; Huang, X; Jiang, M; Li, M; Liu, L; Liu, Y; Lu, M; Song, M; Wang, F; Wang, Y; Yang, D; Yin, J; Zhang, J; Zhang, R	1
Furukawa, Y; Kotani, M; Nakajima, M; Nakamura, K; Okuyama, S; Sawamoto, A; Shinoka, W; Sudo, M; Sugawara, K	1
Fordyce, J; García, AA; Harrison, ML; Rock, J; Wolfe, AS; Zuñiga, JA	1
Chen, HY; Chen, KH; Huang, CH; Huang, YY; Hung, SY; Lin, CN; Lin, CW; Tsai, JS; Yang, HM; Yeh, JT	1
Cao, D; Liu, Z; Ma, F; Ouyang, S; Wu, J	1
Chen, T; Gao, F; Gui, YZ; Qin, YL; Su, M; Tang, XL; Wang, XB; Wang, YP; Wu, WY; Yan, H	1
Hu, AM; Liu, HL; Sun, QQ; Wang, Q; Yin, YW	1
Beeson, WL; Bu, L; Cordero-MacIntyre, Z; De Leon, M; Firek, A; Salto, LM	1
Abo-Elmatty, DM; Ghattas, MH; Khattab, SA; Mehanna, ET; Mesbah, NM	1
Jin, AL; Xie, XR; Yang, YM	1
Banker, P; Bickett, DM; Clancy, DC; Dickerson, SH; Garrido, DM; Golden, PL; Peat, AJ; Sheckler, LR; Sparks, SM; Tavares, FX; Thomson, SA; Weiel, JE	1
Arvanitidis, KI; Christakidis, D; Kyroglou, S; Manolopoulos, VG; Petridis, I; Ragia, G; Tavridou, A; Tiptiri-Kourpeti, A	1
Boeing, H; Döring, F; Fisher, E; Grallert, H; Illig, T; Klapper, M; Pfäfflin, A; Schrezenmeir, J	1
Crispim, D; Dora, JM; Machado, WE; Maia, AL; Rheinheimer, J	1
Atta, M; Fontecave, M; Fujimura, A; Kaitsuka, T; Kimura, S; Matsui, H; Michiue, H; Suzuki, T; Tomizawa, K; Watanabe, S; Wei, FY; Yamagata, K	1
De Filippis, E; Finlayson, J; Langlais, P; Luo, M; Mandarino, LJ; Mapes, R; Mattern, M; Meyer, C; Plummer, E; Tongchinsub, P; Yi, Z	1
Aragonés, A; Argente, J; Azriel, S; Campos-Barros, A; García-Herrero, CM; Gutierrez-Nogués, A; Navas, MA; Rubio-Cabezas, O; Vincent, O	1
Andersen, B; Beck-Nielsen, H; Birk, JB; Højlund, K; Vienberg, SG; Vind, BF; Wojtaszewski, JF	1
Fernández-Real, JM; Moreno-Navarrete, JM; Ortega, F; Ricart, W; Sabater, M; Sánchez-Garrido, MÁ; Tena-Sempere, M; Zorzano, A	1
Cai, H; Cai, J; Tao, G	1
Aloi, C; d'Annunzio, G; Lorini, R; Lugani, F; Marchi, M; Salina, A	1
Buraczyńska, M; Ksiazek, A; Ksiazek, P; Nowicka, T; Spasiewicz, D; Łopatyński, J	1
Cyganek, K; Klupa, T; Malecki, MT; Sieradzki, J	1
Duoqi, S; Jie, L; Junxi, L; Kunsan, X; Rong, Z; Taisan, Z; Wei, D; Weiping, J	1
Schmitz-Peiffer, C; Whitehead, JP	1
Bierhaus, A; Chavakis, T; Hamann, A; Humpert, PM; Isermann, B; Nawroth, P; Nosikov, VV; Reismann, P; Rudofsky, G; Tafel, J; Witte, S	1
Funae, Y; Hiroi, T; Imaoka, S; Kojima, Y; Kondo, M; Matsukura, T; Sakurai, H; Takahashi, S; Ueda, E; Yoshikawa, Y	1
Egashira, T; Ishizuka, T; Kanatsuka, A; Matsui, K; Nozaki, O; Tokuyama, Y	1
Beck, SR; Bowden, DW; Burdon, KP; Freedman, BI; Langefeld, CD; Liu, Y; Rich, SS; Wagenknecht, LE	1
Bianco, AC; Canani, LH; Capp, C; Dora, JM; Gross, JL; Harney, JW; Larsen, PR; Maia, AL; Meyer, EL; Wagner, MS	1
Andersen, G; Borch-Johnsen, K; Drivsholm, T; Glümer, C; Hamid, YH; Hansen, T; Jørgensen, T; Pedersen, O; Rose, CS	1
Blüher, M; Gelbrich, G; Klemm, T; Mehnert, AK; Paschke, R; Siegemund, A; Wiesner, TD	1
Badger, TM; He, L; Mehendale, HM; Ronis, MJ; Simmen, FA	1
Jia, W; Li, M; Liu, L; Lu, H; Xiang, K; Zheng, T	1
Albala, C; Angel, B; Lera, L; Liberman, C; Pérez-Bravo, F; Sanchez, H; Santos, JL; Villarroel, A	1
Canani, LH; Capp, C; Leie, MA; Machado, WE; Maia, AL	1
Acheampong, J; Adeyemo, A; Agyenim-Boateng, K; Akafo, S; Akinsola, FB; Amoah, A; Chen, G; Chen, Y; Doumatey, A; Eghan, BA; Ezepue, F; Fasanmade, O; Huang, H; Johnson, T; Lashley, K; Okafor, G; Oli, J; Rotimi, CN; Zhou, J	1
Kalinin, VN; Olek, K; Poller, W; Schmidt, W	1
Capp, E; Coghlan, M; Galante, P; Häring, HU; Kellerer, M; Kroder, G; Mosthaf, L; Mühlhöfer, A; Siddle, K	1
Iida, M; Imanaka, T; Ito, K; Jinnouchi, H; Kamohara, S; Kan, M; Kanai, F; Nishioka, Y; Ohnishi, T; Todaka, M	1
Baier, LJ; Bennett, PH; Bogardus, C; Eads, J; Knowler, WC; Mochizuki, H; Paolisso, G; Prochazka, M; Sacchettini, JC; Tataranni, PA	1
Bogardus, C; Janssen, RC; Knowler, WC; Takeda, J; Thompson, DB	1
Bell, GI; Hashimoto, N; Kanatsuka, A; Makino, H; Seino, S; Shimada, F; Taira, M; Yoshida, S	1
Albu, J; Allison, DB; Burn, P; Chin, W; Deng, N; Duprat, L; Fisher, SL; Franco, LS; Gu, W; Heymsfield, S; Kissebah, A; Kleyn, PW; Lee, J; Maruti, S; Nathan, J; Pi-Sunyer, FX; Tu, Z; Yagaloff, KA	1
Cupples, LA; Galluzzi, JR; Meigs, JB; Ordovas, JM; Schaefer, EJ; Wilson, PW	1
Ding, W; Jia, W; Lu, J; Sun, D; Tang, J; Xiang, K; Zheng, T	1

Reviews

4 review(s) available for threonine and Diabetes Mellitus, Type 2

Article	Year
Association of the ADIPOQ T45G polymorphism with insulin resistance and blood glucose: a meta-analysis. Endocrine journal, 2014, Volume: 61, Issue:5 Topics: Adiponectin; Amino Acid Substitution; Blood Glucose; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Genetic Association Studies; Genetic Predisposition to Disease; Glycine; Humans; Insulin Resistance; Polymorphism, Single Nucleotide; Threonine	2014
Toll-like receptor 4 gene Asp299Gly and Thr399Ile polymorphisms in type 2 diabetes mellitus: a meta-analysis of 15,059 subjects. Diabetes research and clinical practice, 2015, Volume: 107, Issue:3 Topics: Amino Acid Substitution; Aspartic Acid; Case-Control Studies; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glycine; Humans; Isoleucine; Models, Genetic; Observational Studies as Topic; Polymorphism, Single Nucleotide; Threonine; Toll-Like Receptor 4	2015
Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis. European journal of endocrinology, 2010, Volume: 163, Issue:3 Topics: Adult; Aged; Alanine; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Genetic Markers; Genome-Wide Association Study; Homozygote; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Middle Aged; Multicenter Studies as Topic; Polymorphism, Single Nucleotide; Single-Blind Method; Threonine	2010
IRS-1 regulation in health and disease. IUBMB life, 2003, Volume: 55, Issue:7 Topics: Animals; Cysteine Endopeptidases; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Models, Biological; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase C; Serine; Signal Transduction; Threonine	2003

Other Studies

46 other study(ies) available for threonine and Diabetes Mellitus, Type 2

Article	Year
NMR-Based Metabolomic Analysis for the Effects of Trimethylamine N-Oxide Treatment on C2C12 Myoblasts under Oxidative Stress. Biomolecules, 2022, 09-13, Volume: 12, Issue:9 Topics: Alanine; Catalase; Diabetes Mellitus, Type 2; Glycine; Histidine; Humans; Hydrogen Peroxide; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Malondialdehyde; Methylamines; Myoblasts; Oxidative Stress; Phenylalanine; Phosphorylcholine; Superoxide Dismutase; Threonine; Valine	2022
Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling. Nature communications, 2022, 10-14, Volume: 13, Issue:1 Topics: Adipocytes; Animals; Diabetes Mellitus, Type 2; Homeostasis; Insulin; Insulin Resistance; Male; Mice; Phosphorylation; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Serine; Threonine; Tyrosine	2022
Serine Threonine-Protein Kinase-Derived IW13 Improves Lipid Metabolism via C/EBP-α/SREBP1/FAS Signaling Pathways in HFD-Induced Zebrafish In Vivo Larval Model. Applied biochemistry and biotechnology, 2023, Volume: 195, Issue:8 Topics: Animals; Antioxidants; CCAAT-Enhancer-Binding Protein-alpha; Diabetes Mellitus, Type 2; Lipid Metabolism; Obesity; Oxidative Stress; Protein Kinases; Serine; Signal Transduction; Threonine; Zebrafish	2023
Dietary intakes of methionine, threonine, lysine, arginine and histidine increased risk of type 2 diabetes in Chinese population: does the mediation effect of obesity exist? BMC public health, 2023, 08-15, Volume: 23, Issue:1 Topics: Amino Acids; Arginine; Diabetes Mellitus, Type 2; Diet; East Asian People; Histidine; Humans; Lysine; Male; Methionine; Obesity; Racemethionine; Risk Factors; Threonine	2023
Identification of Ala2Thr mutation in insulin gene from a Chinese MODY10 family. Molecular and cellular biochemistry, 2020, Volume: 470, Issue:1-2 Topics: Adult; Alanine; Cell Line; China; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Family Health; Female; Genetic Predisposition to Disease; Glucose; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Mutation; Mutation, Missense; Pedigree; Protein Structure, Secondary; Structure-Activity Relationship; Threonine; Young Adult	2020
Suppressive effects of the peel of Citrus kawachiensis (Kawachi Bankan) on astroglial activation, tau phosphorylation, and inhibition of neurogenesis in the hippocampus of type 2 diabetic db/db mice. Bioscience, biotechnology, and biochemistry, 2018, Volume: 82, Issue:8 Topics: Animals; Blood Glucose; Citrus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hippocampus; Hyperglycemia; Male; Mice, Inbred C57BL; Microglia; Neurogenesis; Neuroprotective Agents; Phosphorylation; Plant Structures; Powders; Serine; Streptozocin; tau Proteins; Threonine	2018
The additive effect of type 2 diabetes on fibrinogen, von Willebrand factor, tryptophan and threonine in people living with HIV. Amino acids, 2019, Volume: 51, Issue:5 Topics: Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Fibrinogen; HIV; HIV Infections; Humans; Male; Middle Aged; Risk Factors; Threonine; Tryptophan; von Willebrand Factor	2019
Amino acids and wound healing in people with limb-threatening diabetic foot ulcers. Journal of diabetes and its complications, 2019, Volume: 33, Issue:10 Topics: Aged; Aged, 80 and over; Amino Acids; Amputation, Surgical; Arginine; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Foot; Female; Hospitalization; Humans; Isoleucine; Leucine; Male; Threonine; Treatment Outcome; Wound Healing	2019
Sodium tanshinone IIA silate inhibits high glucose-induced vascular smooth muscle cell proliferation and migration through activation of AMP-activated protein kinase. PloS one, 2014, Volume: 9, Issue:4 Topics: Abietanes; AMP-Activated Protein Kinases; Animals; Aorta; Blotting, Western; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme Activation; Flow Cytometry; Glucose; Male; Mice; Mice, Mutant Strains; Mice, Obese; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Primary Cell Culture; Rats, Sprague-Dawley; RNA Interference; Threonine	2014
The Ala54Thr Polymorphism of the Fatty Acid Binding Protein 2 Gene Modulates HDL Cholesterol in Mexican-Americans with Type 2 Diabetes. International journal of environmental research and public health, 2015, Dec-23, Volume: 13, Issue:1 Topics: Adult; Aged; Alanine; Biomarkers; Blood Glucose; Cholesterol, HDL; Diabetes Mellitus, Type 2; Fatty Acid-Binding Proteins; Female; Genetic Markers; Humans; Male; Mexican Americans; Middle Aged; Polymorphism, Single Nucleotide; Threonine; United States	2015
Intestinal fatty acid binding protein Ala54Thr polymorphism is associated with peripheral atherosclerosis combined with type 2 diabetes mellitus. Journal of diabetes, 2017, Volume: 9, Issue:9 Topics: Adult; Alanine; Case-Control Studies; Diabetes Mellitus, Type 2; Egypt; Enzyme-Linked Immunosorbent Assay; Fatty Acid-Binding Proteins; Gene Frequency; Heterozygote; Humans; Middle Aged; Peripheral Arterial Disease; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Threonine	2017
Genetic polymorphisms in extracellular superoxide dismutase Leu53Leu, Arg213Gly, and Ala40Thr and susceptibility to type 2 diabetes mellitus. Genetics and molecular research : GMR, 2016, Dec-02, Volume: 15, Issue:4 Topics: Adult; Alanine; Arginine; Asian People; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Superoxide Dismutase; Threonine	2016
Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues. Bioorganic & medicinal chemistry letters, 2009, Feb-01, Volume: 19, Issue:3 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemistry, Pharmaceutical; Crystallography, X-Ray; Cytochrome P-450 CYP2C9; Diabetes Mellitus, Type 2; Drug Design; Glycine; Glycogen Phosphorylase; Humans; Imides; Inhibitory Concentration 50; Liver; Models, Chemical; ortho-Aminobenzoates; Rats; Serine; Threonine	2009
Thr54 allele of fatty-acid binding protein 2 gene is associated with obesity but not type 2 diabetes mellitus in a Caucasian population. Diabetes research and clinical practice, 2009, Volume: 84, Issue:2 Topics: Adenine; Amino Acid Substitution; Diabetes Mellitus, Type 2; Fatty Acid-Binding Proteins; Genotype; Humans; Obesity; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Thymine; White People	2009
Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals. Molecular genetics and metabolism, 2009, Volume: 98, Issue:4 Topics: Amino Acid Substitution; Diabetes Mellitus, Type 2; Fatty Acid-Binding Proteins; Female; Gastrointestinal Hormones; Genetic Predisposition to Disease; Haplotypes; Humans; Male; Methionine; Middle Aged; Molecular Weight; Obesity; Polymorphism, Single Nucleotide; Protein Isoforms; Threonine	2009
Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice. The Journal of clinical investigation, 2011, Volume: 121, Issue:9 Topics: Adenosine; Animals; Cell Line; Cyclin-Dependent Kinase 5; Diabetes Mellitus, Type 2; Genes, Reporter; Glucagon; Glucose; HEK293 Cells; Humans; Mice; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Nucleic Acid Conformation; Proinsulin; Protein Biosynthesis; Recombinant Fusion Proteins; RNA, Transfer, Amino Acyl; Threonine; tRNA Methyltransferases	2011
Global IRS-1 phosphorylation analysis in insulin resistance. Diabetologia, 2011, Volume: 54, Issue:11 Topics: Adult; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Middle Aged; Obesity; Phosphorylation; Protein Processing, Post-Translational; Quadriceps Muscle; Serine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Threonine	2011
Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing. PloS one, 2012, Volume: 7, Issue:1 Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Child; Child, Preschool; Diabetes Mellitus, Type 2; Female; Glucokinase; Glucose; Humans; Infant; Male; Mutation, Missense; Threonine; Young Adult	2012
Hyperglycaemia normalises insulin action on glucose metabolism but not the impaired activation of AKT and glycogen synthase in the skeletal muscle of patients with type 2 diabetes. Diabetologia, 2012, Volume: 55, Issue:5 Topics: Diabetes Mellitus, Type 2; Female; Glucose; Glucose Clamp Technique; Glycogen Synthase; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Muscle, Skeletal; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Threonine	2012
Phosphorylated S6K1 (Thr389) is a molecular adipose tissue marker of altered glucose tolerance. The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1 Topics: Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Biomarkers; Blotting, Western; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Glucose Tolerance Test; Humans; Insulin Receptor Substrate Proteins; Male; Obesity, Morbid; Phosphorylation; Rats; Rats, Wistar; Reference Values; Reproducibility of Results; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 70-kDa; Rosiglitazone; Thiazolidinediones; Threonine	2013
Association of toll-like receptor 4 polymorphisms with type 2 diabetes mellitus. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2013, Volume: 121, Issue:7 Topics: Adult; Aged; Asian People; Asparagine; Blood Glucose; Blood Pressure; Body Mass Index; Case-Control Studies; Confidence Intervals; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Association Studies; Humans; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Threonine; Toll-Like Receptor 4; Waist-Hip Ratio	2013
Hyperglycaemia and β-cell antibodies: is it always pre-type 1 diabetes? Diabetes research and clinical practice, 2013, Volume: 100, Issue:1 Topics: Autoantibodies; Blood Glucose; Child; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Genetic Testing; Glucokinase; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; Methionine; Point Mutation; Prediabetic State; Threonine	2013
[Association of the renin-angiotensin system gene polymorphism with nephropathy in type II diabetes]. Polskie Archiwum Medycyny Wewnetrznej, 2002, Volume: 108, Issue:2 Topics: Adult; Alanine; Alleles; Angiotensinogen; Case-Control Studies; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Female; Genotype; Humans; Male; Methionine; Middle Aged; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; Threonine	2002
The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 2 diabetes mellitus in a Polish population. Acta diabetologica, 2003, Volume: 40, Issue:2 Topics: Adult; Alanine; Amino Acid Substitution; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Islets of Langerhans; Mutation, Missense; Poland; Polymorphism, Genetic; Threonine; Trans-Activators	2003
The association of Ala54Thr variant of intestinal fatty acid binding protein gene with general and regional adipose tissue depots. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1999, Volume: 14, Issue:1 Topics: Adipose Tissue; Aged; Alanine; Asian People; Body Mass Index; Carrier Proteins; Codon; Diabetes Mellitus, Type 2; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genetic Variation; Genotype; Humans; Male; Middle Aged; Threonine	1999
Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes. Diabetes care, 2004, Volume: 27, Issue:1 Topics: Amino Acid Substitution; Aspartic Acid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Genotype; Glycine; Humans; Isoleucine; Membrane Glycoproteins; Mutation, Missense; Odds Ratio; Polymorphism, Single Nucleotide; Prevalence; Receptors, Cell Surface; Threonine; Toll-Like Receptor 4; Toll-Like Receptors; White People	2004
Blood glucose lowering and toxicological effects of zinc (II) complexes with maltol, threonine, and picolinic acid. Research communications in molecular pathology and pharmacology, 2002, Volume: 112, Issue:1-4 Topics: Animals; Blood Glucose; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2E1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose Tolerance Test; Hypoglycemic Agents; Lethal Dose 50; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Microsomes, Liver; Picolinic Acids; Pyrones; Threonine; Zinc Compounds	2002
Five missense mutations in glucagon-like peptide 1 receptor gene in Japanese population. Diabetes research and clinical practice, 2004, Volume: 66, Issue:1 Topics: Age of Onset; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Body Mass Index; Diabetes Mellitus, Type 2; DNA Primers; Exons; Glucagon-Like Peptide-1 Receptor; Glycated Hemoglobin; Humans; Japan; Methionine; Middle Aged; Models, Molecular; Mutation, Missense; Polymerase Chain Reaction; Protein Conformation; Receptors, Glucagon; Threonine	2004
T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study. Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:4 Topics: Aged; Albuminuria; Aspartic Acid; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exons; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Homozygote; Humans; Linkage Disequilibrium; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Promoter Regions, Genetic; Threonine	2005
The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus. The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:6 Topics: Alanine; Amino Acid Substitution; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Kinetics; Polymorphism, Single Nucleotide; Threonine	2005
Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion. Diabetic medicine : a journal of the British Diabetic Association, 2005, Volume: 22, Issue:7 Topics: Adult; Alanine; Blood Glucose; Case-Control Studies; Codon; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Glucose Tolerance Test; Glucose Transport Proteins, Facilitative; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Monosaccharide Transport Proteins; Phenotype; Polymorphism, Genetic; Threonine	2005
Impact of the Thr789Ala variant of the von Willebrand factor levels, on ristocetin co-factor and collagen binding capacity and its association with coronary heart disease in patients with diabetes mellitus type 2. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2005, Volume: 113, Issue:10 Topics: Adult; Aged; Collagen; Coronary Disease; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Protein Binding; Ristocetin; Threonine; von Willebrand Factor	2005
Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation. The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16 Topics: Alcohol Dehydrogenase; Animals; Binding Sites; Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Chromones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Immunoprecipitation; Insulin; Liver; Male; Models, Biological; Molecular Sequence Data; Morpholines; Phosphorylation; Plasmids; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; Signal Transduction; Threonine; Transcription, Genetic	2006
Ala45Thr variation in neuroD1 gene is associated with early-onset type 2 diabetes with or without diabetic pedigree in Chinese. Molecular and cellular biochemistry, 2006, Volume: 290, Issue:1-2 Topics: Adult; Aged; Alanine; Amino Acid Substitution; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; China; Diabetes Mellitus, Type 2; Gene Frequency; Genetic Predisposition to Disease; Humans; Middle Aged; Pedigree; Polymorphism, Genetic; Threonine	2006
FABP2 Ala54Thr polymorphism and diabetes in Chilean elders. Diabetes research and clinical practice, 2007, Volume: 77, Issue:2 Topics: Aged; Alanine; Amino Acid Substitution; Chile; Cross-Sectional Studies; Diabetes Mellitus, Type 2; DNA; Fatty Acid-Binding Proteins; Female; Gene Frequency; Genotype; Humans; Insulin Resistance; Leukocytes; Male; Threonine	2007
Type 2 deiodinase Thr92Ala polymorphism is not associated with arterial hypertension in type 2 diabetes mellitus patients. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:6 Topics: Alanine; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Hypertension; Insulin Resistance; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Middle Aged; Polymorphism, Single Nucleotide; Reproducibility of Results; Risk Factors; Threonine	2007
Polymorphism of the endothelial nitric oxide synthase gene is associated with diabetic retinopathy in a cohort of West Africans. Molecular vision, 2007, Nov-26, Volume: 13 Topics: Adult; Aged; Alleles; Black People; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Gene Deletion; Genetic Predisposition to Disease; Genotype; Ghana; Glycine; Humans; Male; Middle Aged; Mutagenesis, Insertional; Nigeria; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Threonine	2007
[A new point mutation in the mitochondrial gene ND1, detected in a patient with type II diabetes]. Genetika, 1995, Volume: 31, Issue:8 Topics: Alanine; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Humans; NADH Dehydrogenase; Optic Atrophies, Hereditary; Point Mutation; Threonine	1995
Mechanism of insulin receptor kinase inhibition in non-insulin-dependent diabetes mellitus patients. Phosphorylation of serine 1327 or threonine 1348 is unaltered. The Journal of clinical investigation, 1995, Volume: 96, Issue:1 Topics: Aged; Aged, 80 and over; Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Middle Aged; Phosphorylation; Rats; Receptor, Insulin; Serine; Threonine	1995
Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM. Diabetes, 1995, Volume: 44, Issue:9 Topics: Adult; Aged; Alanine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chlorocebus aethiops; Cysteine; Diabetes Mellitus, Type 2; DNA; DNA Primers; Exons; Female; Genetic Linkage; Humans; Insulin; Japan; Kinetics; Macromolecular Substances; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Polymerase Chain Reaction; Receptor, Insulin; Recombinant Proteins; Threonine; Transfection; Tyrosine	1995
An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance. The Journal of clinical investigation, 1995, Volume: 95, Issue:3 Topics: Adult; Alanine; Alleles; Arizona; Base Sequence; Calorimetry; Carrier Proteins; Chromosomes, Human, Pair 4; Diabetes Mellitus, Type 2; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Female; Gene Frequency; Glucose; Glucose Clamp Technique; Humans; Indians, North American; Insulin Resistance; Male; Models, Molecular; Molecular Sequence Data; Neoplasm Proteins; Oxidation-Reduction; Point Mutation; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Threonine; Tumor Suppressor Proteins	1995
Linkage analysis of acute insulin secretion with GLUT2 and glucokinase in Pima Indians and the identification of a missense mutation in GLUT2. Diabetes, 1994, Volume: 43, Issue:4 Topics: Amino Acid Sequence; Arizona; Base Sequence; Diabetes Mellitus, Type 2; DNA Primers; Epidemiologic Methods; Family; Genetic Linkage; Glucokinase; Glucose Transporter Type 2; Humans; Indians, North American; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Longitudinal Studies; Molecular Sequence Data; Monosaccharide Transport Proteins; Point Mutation; Polymerase Chain Reaction; Threonine	1994
Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family. Diabetologia, 1993, Volume: 36, Issue:5 Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Base Sequence; Blood Glucose; Codon; Diabetes Mellitus, Type 2; Dinucleoside Phosphates; Exons; Female; Glucokinase; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Threonine	1993
Identification and functional analysis of novel human melanocortin-4 receptor variants. Diabetes, 1999, Volume: 48, Issue:3 Topics: Adolescent; Adult; Amino Acid Substitution; Animals; Body Mass Index; Cloning, Molecular; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Isoleucine; Male; Methionine; Mice; Middle Aged; Obesity; Pedigree; Polymorphism, Single-Stranded Conformational; Receptor, Melanocortin, Type 4; Receptors, Peptide; Recombinant Proteins; Threonine; Valine	1999
Association of the Ala54-Thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study. Diabetes care, 2001, Volume: 24, Issue:7 Topics: Alanine; Alcohol Drinking; Apolipoproteins E; Blood Glucose; Cardiovascular Diseases; Carrier Proteins; Cholesterol; Cohort Studies; Diabetes Mellitus, Type 2; DNA; Estrogen Replacement Therapy; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Female; Genetic Carrier Screening; Genotype; Glycated Hemoglobin; Homozygote; Humans; Insulin; Insulin Secretion; Male; Massachusetts; Middle Aged; Neoplasm Proteins; Polymorphism, Genetic; Postmenopause; Prospective Studies; Risk Factors; Sex Characteristics; Smoking; Threonine; Triglycerides; Tumor Suppressor Proteins	2001
The impact of codon 54 variation in intestinal fatty acid binding protein gene on the pathogenesis of diabetes mellitus in Chinese. Chinese medical journal, 1999, Volume: 112, Issue:2 Topics: Alanine; Asian People; Carrier Proteins; China; Codon; Diabetes Mellitus, Type 2; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Genetic Variation; Humans; Insulin; Insulin Resistance; Insulin Secretion; Neoplasm Proteins; Threonine; Tumor Suppressor Proteins	1999