Compounds > threonine

threonine and Colorectal Neoplasms

threonine has been researched along with Colorectal Neoplasms in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.85)18.2507
2000's10 (38.46)29.6817
2010's10 (38.46)24.3611
2020's5 (19.23)2.80

Authors

AuthorsStudies
Fukui, T; Horitani, S; Kishimoto, M; Matsumoto, Y; Miyamoto, S; Naganuma, M; Nishio, A; Okazaki, K; Suzuki, R; Takahashi, YU; Tanimura, Y; Tomiyama, T1
Brezmes, J; Cumeras, R; Gumà, J; Llambrich, M1
Kettenbach, AN; Mariano, NC; Nasa, I; Rusin, SF1
Bi, HC; Chen, G; Chen, Y; Feng, JX; Gao, S; Hu, JJ; Jia, WH; Jiang, YM; Jin, Y; Ju, HQ; Kopetz, S; Li, YQ; Liu, J; Liu, KY; Liu, ZX; Lu, YX; Ogasawara, M; Pan, ZZ; Sheng, H; Tian, F; Wang, F; Wang, YN; Xie, D; Xu, RH; Yun, JP; Zeng, ZL; Zhang, C; Zhao, Q1
Garcia-Martin, F; Hayakawa, S; Hinou, H; Kamiyama, T; Matsuoka, K; Matsushita, T; Nishimura, SI; Nouso, K; Taketomi, A; Wakui, H; Yokoi, Y1
He, Y; Negandhi, AA; Parfrey, PS; Penney, ME; Savas, S; Yilmaz, YE1
Jeon, Y; Jeong, HJ; Jeong, JB; Kim, YS; Koo, JS; Park, GH; Song, HM1
Branders, S; De Ridder, M; Defresne, F; Dieu, M; Dupont, P; Feron, O; Grandjean, M; Raes, M; Sermeus, A1
Boureme, D; Buzy, A; Copin, MC; Dehennaut, V; El Yazidi-Belkoura, I; Ferrara, P; Guinez, C; Lefebvre, T; Loyaux, D; Mir, AM; Olivier-Van Stichelen, S; Zachayus, JL1
Eo, HJ; Jeong, JB; Kim, MK; Koo, JS; Lee, JR; Lee, JW; Lee, MH; Park, GH; Song, HM1
Beaudry, K; Cagnol, S; Carrier, J; Lemieux, E; Rivard, N1
Ding, K; Jeyabal, PV; Shi, ZZ; Song, R; Wang, G; Weiskoff, AM; Xu, D1
Jeong, JB; Park, GH; Song, HM1
Dimberg, J; Hugander, A; Löfgren, S; Wågsäter, D; Zar, N1
Agúndez, JA; de Murillo, SG; Gervasini, G; Ladero, JM1
Gul, YA; Ithnin, H; Khor, TO; Seow, HF1
Chen, K; Chen, Q; Fan, CH; Jin, MJ; Ma, XY; Song, L; Yao, KY; Zhu, YM1
Byrski, T; Castaneda, J; Cybulski, C; Debniak, B; Debniak, T; Górski, B; Huzarski, T; Jaworowska, E; Klujszo-Grabowska, E; Kurzawski, G; Lener, M; Lubinski, J; Masojc, B; Matyjasik, J; Medrek, K; Mierzejewski, M; Narod, S; Nej-Wołosiak, K; Oszurek, O; Oszutowska, D; Rozmiarek, A; Scott, RJ; Suchy, J; Szymańska, A; Szymańska, J; Teodorczyk, U; van de Wetering, T; Złowocka, E1
Agata, S; Amadori, A; Belluco, C; Bertorelle, R; Biscuola, M; D'Andrea, E; De Salvo, GL; Esposito, G; Menin, C; Montagna, M; Nitti, D; Quaggio, M; Scaini, MC1
Dorie, MJ; Freiberg, RA; Giaccia, AJ; Hammond, EM; Welford, SM1
Berthonaud, V; Chevalier, A; Ducrot, C; Leteurtre, F; Mann, C; Marsolier-Kergoat, MC; Oliva-Trastoy, M1
Byrski, T; Cybulski, C; D Ecedil Bniak, T; Górski, B; Grabowska, E; Gronwald, J; Huzarski, T; Kurzawski, G; Kurzwaski, G; Kładny, J; Lubiński, J; Narod, SA; Suchy, J; Wokołorczyk, D1
Houlston, RS; Hubner, RA1
Dive, C; Griffiths, JR; Welman, A; Whetton, AD1
DeNobile, JW; Dimond, E; Grogan, L; Hausner, P; Kirsch, IR; Kitaeva, MN; Nakahara, K; Soballe, PW; Williams, JP1
Bassi, C; Falconi, M; Moore, PS; Scarpa, A; Zamboni, G1

Reviews

2 review(s) available for threonine and Colorectal Neoplasms

ArticleYear
Urine NMR Metabolomics for Precision Oncology in Colorectal Cancer.
    International journal of molecular sciences, 2022, Sep-22, Volume: 23, Issue:19

    Topics: Acetates; Acetone; Biomarkers; Carnitine; Colorectal Neoplasms; Creatinine; Glucose; Humans; Lysine; Metabolomics; Precision Medicine; Prospective Studies; Pyruvic Acid; Threonine; Urea

2022
MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations.
    International journal of cancer, 2007, Mar-01, Volume: 120, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Cysteine; Female; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Threonine

2007

Other Studies

24 other study(ies) available for threonine and Colorectal Neoplasms

ArticleYear
Linker Threonine-phosphorylated Smad2/3 Is a Biomarker of Colorectal Neoplastic Stem-like Cells that Correlates With Carcinogenesis.
    Anticancer research, 2021, Volume: 41, Issue:10

    Topics: Biomarkers, Tumor; Carcinogenesis; Colorectal Neoplasms; Humans; Intestinal Mucosa; Neoplastic Stem Cells; Phosphorylation; Smad2 Protein; Smad3 Protein; Threonine; Tumor Suppressor Protein p53

2021
Inducible Protein Degradation as a Strategy to Identify Phosphoprotein Phosphatase 6 Substrates in RAS-Mutant Colorectal Cancer Cells.
    Molecular & cellular proteomics : MCP, 2023, Volume: 22, Issue:8

    Topics: Colorectal Neoplasms; Humans; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Proteolysis; Threonine

2023
AMPKα1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation.
    Oncogene, 2020, Volume: 39, Issue:3

    Topics: Aged; AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Drug Synergism; Female; Gene Knockdown Techniques; Glutathione Reductase; Humans; Kaplan-Meier Estimate; Male; Mice; Middle Aged; Neoplasm Staging; Oxaliplatin; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; RNA, Small Interfering; Stress, Physiological; Survival Rate; Threonine; Xenograft Model Antitumor Assays

2020
Impaired O-Glycosylation at Consecutive Threonine TTX Motifs in Mucins Generates Conformationally Restricted Cancer Neoepitopes.
    Biochemistry, 2020, 03-31, Volume: 59, Issue:12

    Topics: Adult; Antigens, Neoplasm; Autoantibodies; Colorectal Neoplasms; Female; Glycosylation; Humans; Intrinsically Disordered Proteins; Male; Middle Aged; Molecular Conformation; Mucin-2; Neoplasm Staging; Nuclear Magnetic Resonance, Biomolecular; Threonine; Tumor Cells, Cultured; Tumor Microenvironment

2020
XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer.
    PloS one, 2018, Volume: 13, Issue:2

    Topics: Colorectal Neoplasms; DNA-Binding Proteins; Humans; Methionine; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Threonine; Thymidylate Synthase

2018
Anti-cancer activity of
    Die Pharmazie, 2017, Jun-01, Volume: 72, Issue:6

    Topics: Antineoplastic Agents; Bacillus amyloliquefaciens; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Down-Regulation; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; Humans; Phosphorylation; Rhizosphere; Soil Microbiology; Threonine

2017
Hypoxia integration in the serological proteome analysis unmasks tumor antigens and fosters the identification of anti-phospho-eEF2 antibodies as potential cancer biomarkers.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Aged; Amino Acid Sequence; Animals; Antigens, Neoplasm; Autoantibodies; Biomarkers, Tumor; Cell Hypoxia; Cell Proliferation; Colorectal Neoplasms; HCT116 Cells; HT29 Cells; Humans; Immunoassay; Male; Mice; Molecular Sequence Data; Peptide Elongation Factor 2; Phosphoproteins; Phosphorylation; Proteomics; Serologic Tests; Threonine

2013
O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014, Volume: 28, Issue:8

    Topics: Acetylglucosamine; Adenocarcinoma; Adherens Junctions; alpha Catenin; Amino Acid Sequence; Animals; beta Catenin; beta-N-Acetylhexosaminidases; Colon; Colorectal Neoplasms; Dietary Carbohydrates; Enzyme Inhibitors; Glucose; Glycosylation; HEK293 Cells; Humans; Hyperglycemia; Intestinal Mucosa; Male; MCF-7 Cells; Mice; Mice, Inbred C57BL; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Neoplasm Proteins; Phosphorylation; Protein Interaction Mapping; Protein Processing, Post-Translational; Protein Stability; Proteolysis; RNA, Small Interfering; Threonine; Wnt Signaling Pathway

2014
Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of threonine-286 in human colorectal cancer cells.
    International immunopharmacology, 2015, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; HCT116 Cells; Humans; Leupeptins; NF-kappa B; Nitriles; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Proteolysis; Silybum marianum; Silymarin; Sulfones; Threonine

2015
Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer.
    Oncogene, 2015, Sep-17, Volume: 34, Issue:38

    Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Cell Line, Tumor; Colorectal Neoplasms; Genes, ras; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Oncogenes; Phosphorylation; Serine; Signal Transduction; Threonine; Transcription Factor 4; Transcription Factors; Wnt Signaling Pathway

2015
Obg-like ATPase 1 regulates global protein serine/threonine phosphorylation in cancer cells by suppressing the GSK3β-inhibitor 2-PP1 positive feedback loop.
    Oncotarget, 2016, Jan-19, Volume: 7, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Blotting, Western; Colorectal Neoplasms; Feedback, Physiological; Female; Glycogen Synthase Kinase 3 beta; GTP-Binding Proteins; Humans; Immunoenzyme Techniques; Mice; Mice, SCID; Ovarian Neoplasms; Phosphoproteins; Phosphorylation; Protein Phosphatase 1; Proteins; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
The coffee diterpene kahweol suppresses the cell proliferation by inducing cyclin D1 proteasomal degradation via ERK1/2, JNK and GKS3β-dependent threonine-286 phosphorylation in human colorectal cancer cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 95

    Topics: Antineoplastic Agents; Blotting, Western; Cell Proliferation; Coffee; Colorectal Neoplasms; Cyclin D1; Diterpenes; Glycogen Synthase Kinase 3 beta; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Phosphorylation; Proteasome Endopeptidase Complex; Proteolysis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Threonine; Tumor Cells, Cultured

2016
Pigment epithelium-derived factor expression in colorectal cancer patients.
    Cancer investigation, 2010, Volume: 28, Issue:8

    Topics: Amino Acid Substitution; Angiogenesis Inhibitors; Colorectal Neoplasms; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Genotype; Humans; Interleukin-6; Methionine; Nerve Growth Factors; Polymorphism, Single Nucleotide; Protease Inhibitors; Reference Values; Serpins; Threonine

2010
CYP2W1 variant alleles in Caucasians and association of the CYP2W1 G541A (Ala181Thr) polymorphism with increased colorectal cancer risk.
    Pharmacogenomics, 2010, Volume: 11, Issue:7

    Topics: Aged; Alleles; Amino Acid Substitution; Case-Control Studies; Colorectal Neoplasms; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Female; Gene Frequency; Haplotypes; Humans; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk; Threonine; White People

2010
Positive correlation between overexpression of phospho-BAD with phosphorylated Akt at serine 473 but not threonine 308 in colorectal carcinoma.
    Cancer letters, 2004, Jul-16, Volume: 210, Issue:2

    Topics: Age Factors; Aged; Apoptosis; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; Male; Middle Aged; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Up-Regulation

2004
The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorectal cancer in a Chinese population.
    Cancer genetics and cytogenetics, 2005, Volume: 163, Issue:1

    Topics: Adult; Aged; Amino Acid Substitution; Base Sequence; China; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; DNA Primers; DNA Repair; DNA-Binding Proteins; Female; Genotype; Humans; Male; Methionine; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Rectal Neoplasms; Registries; Risk Factors; Threonine

2005
CDKN2A common variant and multi-organ cancer risk--a population-based study.
    International journal of cancer, 2006, Jun-15, Volume: 118, Issue:12

    Topics: Adult; Aged; Alanine; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Female; Genes, p16; Genetic Variation; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Odds Ratio; Poland; Prevalence; Risk Assessment; Risk Factors; Threonine

2006
Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status.
    Journal of the National Cancer Institute, 2006, Feb-15, Volume: 98, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Colorectal Neoplasms; Female; Genes, p53; Genotype; Glycine; Humans; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Threonine

2006
DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response.
    Molecular and cellular biology, 2006, Volume: 26, Issue:5

    Topics: Acetylcysteine; Apoptosis; Ataxia Telangiectasia; Carcinoma; cdc25 Phosphatases; Cell Hypoxia; Cell Survival; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Damage; Free Radical Scavengers; G2 Phase; Humans; Oxygen; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Threonine; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2006
The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
    Oncogene, 2007, Mar-01, Volume: 26, Issue:10

    Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Damage; DNA-Binding Proteins; Enzyme Activation; Humans; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae Proteins; Threonine; Tumor Cells, Cultured; Tumor Suppressor Proteins

2007
Germline CHEK2 mutations and colorectal cancer risk: different effects of a missense and truncating mutations?
    European journal of human genetics : EJHG, 2007, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Mutational Analysis; Female; Germ-Line Mutation; Humans; Isoleucine; Male; Middle Aged; Mutation, Missense; Protein Serine-Threonine Kinases; Risk; Sequence Deletion; Threonine

2007
Protein kinase C delta is phosphorylated on five novel Ser/Thr sites following inducible overexpression in human colorectal cancer cells.
    Protein science : a publication of the Protein Society, 2007, Volume: 16, Issue:12

    Topics: Amino Acid Sequence; Catalytic Domain; Colorectal Neoplasms; Doxycycline; Humans; Mass Spectrometry; Molecular Sequence Data; Phosphorylation; Protein Kinase C-delta; Serine; Threonine

2007
Mutations in beta-catenin are uncommon in colorectal cancer occurring in occasional replication error-positive tumors.
    Cancer research, 1997, Oct-15, Volume: 57, Issue:20

    Topics: Adult; Aged; Alanine; Amino Acid Substitution; Base Sequence; beta Catenin; Cadherins; Colorectal Neoplasms; Cytoskeletal Proteins; DNA Replication; Exons; Female; Humans; Male; Microsatellite Repeats; Middle Aged; Neoplasm Staging; Phenotype; Point Mutation; Threonine; Trans-Activators; Tumor Cells, Cultured

1997
A novel germline mutation, P48T, in the CDKN2A/p16 gene in a patient with pancreatic carcinoma.
    Human mutation, 2000, Volume: 16, Issue:5

    Topics: Aged; Carcinoma; Colorectal Neoplasms; Cyclin-Dependent Kinases; Female; Genes, p16; Germ-Line Mutation; Humans; Male; Pancreatic Neoplasms; Proline; Threonine

2000