Compounds > threonine

threonine and Cell Transformation, Neoplastic

threonine has been researched along with Cell Transformation, Neoplastic in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.00)18.7374
1990's4 (10.00)18.2507
2000's16 (40.00)29.6817
2010's14 (35.00)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Cao, X; Lai, S; Sun, W; Wang, D1
Abe, T; Ando, Y; Furuta, Y; Hayashizaki, Y; Kaneko, MK; Kaneko, S; Kato, Y; Kawaji, H; Kondo, T; Machitani, M; Masutomi, K; Matsuda, Y; Morioka, MS; Shiozawa, K; Shirouzu, M; Shoji, S; Yamada, S; Yamashita, T; Yasukawa, M1
Cavey, GS; Mapp, AK; Old, M; Pan, Q; Piao, L; Teknos, TN; Xie, X1
Du, Y; Fu, H; Han, Q; Khuri, FR; Li, Z; Park, HR; Pham, CD; Shi, Z; Zhang, Y1
Anastasiadis, PZ; Copland, JA; Huveldt, D; Kourtidis, A; Yanagisawa, M1
Banerjee, S; Dixon, JE; Guo, X; Huang, L; Wang, X; Wang, Z; Yang, J1
Che, R; Fei, P; Jia, W; Panneerselvam, J; Su, M; Xie, G; Zhang, J1
Aburatani, H; Aihara, H; Cheung, E; Doiguchi, M; Hayashi, T; Higashi, M; Ikura, T; Imamura, Y; Inoue, S; Ito, T; Kato, M; Kodama, Y; Koseki, H; Mizusaki, H; Nakagawa, T; Nakayama, T; Oki, M; Takayama, KI; Takeshima, Y; Yoneda, M1
Elabd, M; Freund, P; Gouilleux, F; Groner, B; Hager, M; Han, X; Kerenyi, MA; Krämer, OH; Moriggl, R; Pham, HTT; Sexl, V; Valent, P; Wagner, T; Wingelhofer, B1
Addona, TA; Agarwal, NK; Boulbes, D; Carr, SA; Chen, CH; Keshishian, H; Magnuson, MA; Peterson, TR; Sabatini, DM; Sarbassov, dos D; Shaikenov, T1
Bode, AM; Dong, Z; Li, T; Li, X; Liu, K; Ma, W; Peng, C; Shi, G; Wen, W; Zhang, J; Zhu, F; Zykova, T1
Alawi, F; Chou, SJ1
Castilla, C; Giráldez, S; Herrero-Ruiz, J; Japón, MÁ; Limón-Mortés, MC; Mora-Santos, M; Romero, F; Sáez, C; Tortolero, M1
Eberwine, JH; Kim, MS; Klein-Szanto, AJ; Morris, JF; Rustgi, A; Schochet, T; Sul, JY1
Harrison, AM; Jeganathan, KB; Malureanu, L; Ricke, RM; van Deursen, JM1
Calabrò, V; Calogero, RA; La Mantia, G; Pollice, A; Ranieri, M; Sansone, F; Santoriello, C; Vivo, M1
Conti, CJ; Fox, SR; Giesting, S; Knudsen, ES; Lambeck, TC; Lan, Z; Senderowicz, AM; Solomon, DA; Wang, Y1
Allan, LA; Brady, S; Clarke, PR; Magee, G; Morrice, N; Pathak, S1
Appella, E; Knights, CD; Kulesz-Martin, M; Liu, Y1
Gallick, GE; Kim, LS; Minard, ME; Price, JE1
Arnold, H; Chasse, D; Counter, CM; Cunningham, M; Hahn, WC; Ivaldi, G; Means, AR; Monteith, T; Nevins, JR; Sears, R; Shenolikar, S; Stukenberg, PT; Uchida, T; Yeh, E1
Copeland, TD; Johnson, PF; Kaldis, P; Sebastian, T; Shuman, JD; Smart, RC; Zhu, S1
Clurman, BE; D Tsuchiya, K; Firpo, E; Kostner, H; Loeb, KR; Norwood, T; Roberts, JM1
Lee, MH; Yang, H; Yang, HY; Zhao, R1
Berndt, N; Liu, CW; Wang, RH1
Barra, JL; Brunotto, M; Calderón, O; Crosa, M; Malberti, A; Piñas, E; Plavnik, L; Zárate, AM1
Ethier, SP; Moffa, AB1
Child, ES; Elphick, LM; Mann, DJ; Yarmishyn, A1
Barry, SP; Knight, RA; Latchman, DS; Melino, G; Soond, SM; Stephanou, A1
Chang, HS; Liang, YJ; Wang, CY; Yu, WC1
Catling, AD; Reddy, GR; Reuter, CW; Schaeffer, HJ; Weber, MJ1
Barrett, JF; Chou, TY; Dang, CV; Hann, SR; Hoang, AT; Lewis, BC; Lutterbach, B; Raffeld, M; Yano, T1
Evan, G; Fisher, C; Littlewood, T; Pulverer, BJ; Vousden, K; Woodgett, JR1
Bansal, RK; Dai, JL; Kern, SE1
Baserga, R; Edmonds, P; McCormick, J; Morrione, A; Navarro, M; Reiss, K; Romano, G; Sacchi, A; Valentinis, B; Zanocco-Marani, T1
Alt, JR; Cleveland, JL; Diehl, JA; Hannink, M1
Hare, JD; Marinetti, GV; Mark-Malchoff, D; Meisler, A1
Bertics, PJ; Gill, GN; Santon, JB1
Goldman, M; Griffin, AC1
Philipson, L1

Reviews

2 review(s) available for threonine and Cell Transformation, Neoplastic

ArticleYear
The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression.
    Breast cancer research and treatment, 2004, Volume: 84, Issue:1

    Topics: Animals; Apoptosis; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Disease Progression; GTP Phosphohydrolases; Guanine Nucleotide Exchange Factors; Humans; Mice; Neoplasm Invasiveness; Neoplasms; Phosphorylation; Proteins; rho GTP-Binding Proteins; Signal Transduction; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Threonine

2004
Epidermal growth factor and its receptor.
    Molecular and cellular endocrinology, 1987, Volume: 51, Issue:3

    Topics: Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Gene Amplification; Humans; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogenes; Threonine; Tyrosine

1987

Other Studies

38 other study(ies) available for threonine and Cell Transformation, Neoplastic

ArticleYear
Serine/threonine-protein kinase STK24 induces tumorigenesis by regulating the STAT3/VEGFA signaling pathway.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:3

    Topics: A549 Cells; Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Protein Serine-Threonine Kinases; Signal Transduction; STAT3 Transcription Factor; Threonine; Vascular Endothelial Growth Factor A

2023
CDK1 dependent phosphorylation of hTERT contributes to cancer progression.
    Nature communications, 2020, 03-25, Volume: 11, Issue:1

    Topics: Animals; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Mice; Mitosis; Mutation; Neoplasms; Phosphorylation; RNA-Dependent RNA Polymerase; Telomerase; Threonine

2020
Phosphorylation of Nanog is essential to regulate Bmi1 and promote tumorigenesis.
    Oncogene, 2014, Apr-17, Volume: 33, Issue:16

    Topics: Animals; Base Sequence; Binding Sites; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; HEK293 Cells; Homeodomain Proteins; Humans; Immunoblotting; Mass Spectrometry; Mice; Mice, Nude; Mutation; Nanog Homeobox Protein; Phosphorylation; Polycomb Repressive Complex 1; Promoter Regions, Genetic; Protein Kinase C-epsilon; Threonine; Transplantation, Heterologous

2014
Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs.
    Oncotarget, 2014, May-30, Volume: 5, Issue:10

    Topics: 14-3-3 Proteins; Adenocarcinoma; Amino Acid Motifs; Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Survival; Cell Transformation, Neoplastic; Chromatography, Affinity; Gene Knockdown Techniques; Heterografts; Humans; Immunoprecipitation; Lung Neoplasms; Mice; Mice, SCID; Microfilament Proteins; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Phosphorylation; RNA, Small Interfering; Serine; src Homology Domains; Threonine; Transfection

2014
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Renal Cell; Catenins; Cell Transformation, Neoplastic; Delta Catenin; Female; Humans; Immunoenzyme Techniques; Immunoprecipitation; Kidney Neoplasms; Phosphoproteins; Phosphorylation; Protein Binding; Serine; Threonine; Tissue Array Analysis; Tumor Cells, Cultured; Tyrosine

2015
Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis.
    Nature cell biology, 2016, Volume: 18, Issue:2

    Topics: Animals; ATPases Associated with Diverse Cellular Activities; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; CRISPR-Cas Systems; Dyrk Kinases; Female; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Mice, Nude; Phosphorylation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteolysis; RNA Interference; Signal Transduction; Threonine; Time Factors; Transfection; Tumor Burden

2016
Distinct Metabolic Signature of Human Bladder Cancer Cells Carrying an Impaired Fanconi Anemia Tumor-Suppressor Signaling Pathway.
    Journal of proteome research, 2016, Apr-01, Volume: 15, Issue:4

    Topics: Alternative Splicing; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chromatography, Liquid; Epithelial Cells; Fanconi Anemia Complementation Group L Protein; Gene Expression; Humans; Mass Spectrometry; Metabolome; Methionine; Phenylalanine; Protein Isoforms; Signal Transduction; Threonine; Transgenes

2016
Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1.
    Molecular cell, 2016, 10-06, Volume: 64, Issue:1

    Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin; Cyclin D1; Drosophila melanogaster; Drosophila Proteins; Gene Expression Regulation, Neoplastic; HeLa Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Mice; Oligopeptides; Phosphorylation; Protamine Kinase; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Threonine; Ubiquitination

2016
O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.
    Leukemia, 2017, Volume: 31, Issue:10

    Topics: Acetylglucosamine; Animals; Cell Line; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glycosylation; Humans; Interleukin-3; Lymphoid Tissue; Male; Mice; Mutagenesis, Site-Directed; Myeloproliferative Disorders; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Radiation Chimera; Recombinant Fusion Proteins; Signal Transduction; STAT5 Transcription Factor; T-Lymphocytes; Threonine; Transcriptional Activation; Tumor Suppressor Proteins

2017
Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.
    Molecular cancer research : MCR, 2010, Volume: 8, Issue:6

    Topics: Animals; Carrier Proteins; Catalytic Domain; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Fibroblasts; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Signal Transduction; Threonine; TOR Serine-Threonine Kinases

2010
P21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformation.
    Carcinogenesis, 2011, Volume: 32, Issue:5

    Topics: Animals; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermal Growth Factor; Epidermis; Humans; Immunoenzyme Techniques; Immunoprecipitation; Melanoma; Mice; Mutation; p21-Activated Kinases; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Skin; Skin Neoplasms; Threonine; Tissue Array Analysis; Transcription Factor AP-1

2011
Expression of DNA damage response biomarkers during oral carcinogenesis.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 111, Issue:3

    Topics: Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Checkpoint Kinase 2; DNA Damage; DNA Replication; Epithelium; Genes, Tumor Suppressor; Histones; Humans; Hyperplasia; Immunohistochemistry; Mouth Mucosa; Mouth Neoplasms; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Threonine

2011
A single mutation in Securin induces chromosomal instability and enhances cell invasion.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Chlorocebus aethiops; Chromosomal Instability; COS Cells; Gene Expression; HCT116 Cells; HeLa Cells; Humans; Microarray Analysis; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms; Point Mutation; Securin; Threonine; Transfection

2013
Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma.
    Human pathology, 2013, Volume: 44, Issue:5

    Topics: Adenocarcinoma; Amino Acid Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; ets-Domain Protein Elk-1; Humans; Immunohistochemistry; Neoplasms; Phosphorylation; Threonine; Transcriptional Activation

2013
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression.
    The Journal of cell biology, 2012, Dec-10, Volume: 199, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Aurora Kinase B; Aurora Kinases; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Segregation; Female; Fibroblasts; Gene Knock-In Techniques; Histones; M Phase Cell Cycle Checkpoints; Male; Mice; Phosphorylation; Protein Serine-Threonine Kinases; Threonine

2012
Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Loci; Humans; Phosphorylation; Protein Kinase C; Protein Stability; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Threonine; Transfection; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53

2013
Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation.
    The Journal of biological chemistry, 2003, Aug-08, Volume: 278, Issue:32

    Topics: 3T3 Cells; Alleles; Alternative Splicing; Animals; Binding Sites; Cell Cycle; Cell Nucleus; Cell Transformation, Neoplastic; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cytoplasm; DNA; Flow Cytometry; Green Fluorescent Proteins; Humans; Immunoblotting; Luminescent Proteins; Mice; Microscopy, Fluorescence; Models, Genetic; Neoplasms; Phosphorylation; Plasmids; Polymorphism, Genetic; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Mas; Proto-Oncogene Proteins; Retinoblastoma Protein; Threonine; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2003
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.
    Nature cell biology, 2003, Volume: 5, Issue:7

    Topics: 3T3 Cells; Animals; Apoptosis; Base Sequence; Caspase 3; Caspase 9; Caspases; Cell Survival; Cell Transformation, Neoplastic; Cytochrome c Group; Enzyme Inhibitors; Epidermal Growth Factor; Eukaryotic Cells; HeLa Cells; Humans; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; Signal Transduction; Threonine

2003
Defective p53 post-translational modification required for wild type p53 inactivation in malignant epithelial cells with mdm2 gene amplification.
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Acetyltransferases; Animals; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA; DNA Damage; DNA, Complementary; Dose-Response Relationship, Radiation; Epithelial Cells; Flow Cytometry; Gene Amplification; Genes, p53; Genes, Reporter; Green Fluorescent Proteins; Histone Acetyltransferases; HSP70 Heat-Shock Proteins; Humans; Immunoblotting; Luminescent Proteins; Mice; Nuclear Proteins; p300-CBP Transcription Factors; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Proto-Oncogene Proteins p21(ras); Threonine; Time Factors; Transcription Factors; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53; Ultraviolet Rays

2003
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
    Nature cell biology, 2004, Volume: 6, Issue:4

    Topics: Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Cell Line; Cell Transformation, Neoplastic; Genes, myc; Humans; Mice; Mutation; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-myc; Rats; RNA Stability; Serine; Signal Transduction; Threonine

2004
Cell cycle-dependent phosphorylation of C/EBPbeta mediates oncogenic cooperativity between C/EBPbeta and H-RasV12.
    Molecular and cellular biology, 2004, Volume: 24, Issue:17

    Topics: Amino Acid Sequence; Animals; CCAAT-Enhancer-Binding Protein-beta; CDC2-CDC28 Kinases; Cell Cycle; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; Genes, ras; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; NIH 3T3 Cells; Phosphorylation; Proto-Oncogene Proteins c-raf; ras Proteins; Sequence Alignment; Serine; Signal Transduction; Threonine

2004
A mouse model for cyclin E-dependent genetic instability and tumorigenesis.
    Cancer cell, 2005, Volume: 8, Issue:1

    Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Chromosome Breakage; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cytogenetic Analysis; Disease Models, Animal; Female; Genomic Instability; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; ras Proteins; Threonine; Translocation, Genetic; Tumor Suppressor Protein p53; Ubiquitin

2005
Modified p27 Kip1 is efficient in suppressing HER2-mediated tumorigenicity.
    Journal of cellular biochemistry, 2006, May-01, Volume: 98, Issue:1

    Topics: Amino Acid Substitution; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; COP9 Signalosome Complex; Cyclin-Dependent Kinase Inhibitor p27; Female; Gene Deletion; Growth Inhibitors; Intracellular Signaling Peptides and Proteins; Mice; Mice, Nude; Mitogens; NIH 3T3 Cells; Peptide Hydrolases; Protein Binding; Receptor, ErbB-2; Threonine; Transfection

2006
Protein phosphatase 1alpha activity prevents oncogenic transformation.
    Molecular carcinogenesis, 2006, Volume: 45, Issue:9

    Topics: Animals; Apoptosis; Caspases; Cell Transformation, Neoplastic; Cyclin D1; Humans; Mice; Mutation; Phosphoprotein Phosphatases; Phosphorylation; ras Proteins; Retinoblastoma Protein; Threonine; Transfection; Tumor Suppressor Proteins

2006
Early phenotypic and genotypic alterations in submandibular gland oncogenesis in rats.
    Acta odontologica latinoamericana : AOL, 2006, Volume: 19, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Substitution; Analysis of Variance; Animals; Asparagine; Cell Transformation, Neoplastic; DNA Mutational Analysis; Immunoenzyme Techniques; Male; Mutation, Missense; Point Mutation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Submandibular Gland Neoplasms; Threonine; Tumor Suppressor Protein p53

2006
Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells.
    Journal of cellular physiology, 2007, Volume: 210, Issue:3

    Topics: Alternative Splicing; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial Cells; Female; Fibroblast Growth Factor 7; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Mammary Glands, Human; Protein Isoforms; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction; Threonine

2007
Differential regulation of the cyclin-dependent kinase inhibitors p21(Cip1) and p27(Kip1) by phosphorylation directed by the cyclin encoded by Murine Herpesvirus 68.
    Experimental cell research, 2008, Jan-01, Volume: 314, Issue:1

    Topics: Animals; Catalytic Domain; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; DNA, Viral; Down-Regulation; Enzyme Activation; Gene Expression Regulation, Viral; Genes, cdc; Herpesviridae Infections; Mice; NIH 3T3 Cells; Phosphorylation; Protein Binding; Rhadinovirus; S Phase; Threonine; Tumor Virus Infections; Viral Proteins

2008
p73-mediated transcriptional activity is negatively regulated by polo-like kinase 1.
    Cell cycle (Georgetown, Tex.), 2008, May-01, Volume: 7, Issue:9

    Topics: Amino Acid Sequence; Apoptosis Regulatory Proteins; Binding Sites; Cell Cycle Proteins; Cell Transformation, Neoplastic; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Nuclear Proteins; Phosphorylation; Polo-Like Kinase 1; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Threonine; Transcriptional Activation; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Proteins

2008
DYRK1A stabilizes HPV16E7 oncoprotein through phosphorylation of the threonine 5 and threonine 7 residues.
    The international journal of biochemistry & cell biology, 2008, Volume: 40, Issue:11

    Topics: Animals; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Dyrk Kinases; Humans; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Phosphorylation; Point Mutation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA Interference; Threonine

2008
A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function.
    Molecular and cellular biology, 1995, Volume: 15, Issue:10

    Topics: Amino Acid Sequence; Animals; Blood; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Fibroblasts; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Recombinant Fusion Proteins; Sequence Deletion; Threonine

1995
A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain.
    Molecular and cellular biology, 1995, Volume: 15, Issue:8

    Topics: Alleles; Amino Acid Sequence; Base Sequence; Burkitt Lymphoma; Cell Transformation, Neoplastic; Cyclins; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Models, Genetic; Molecular Sequence Data; Mutation; Nuclear Proteins; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-myc; Retinoblastoma-Like Protein p107; Structure-Activity Relationship; Suppression, Genetic; TATA-Box Binding Protein; Threonine; Transcription Factors; Transcriptional Activation

1995
Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo.
    Oncogene, 1994, Volume: 9, Issue:1

    Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Genes, ras; Humans; Mice; Molecular Sequence Data; Phosphorylation; Proto-Oncogene Proteins c-myc; Rats; Serine; Threonine

1994
G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Feb-16, Volume: 96, Issue:4

    Topics: Amino Acid Substitution; Apoptosis; Arginine; Breast Neoplasms; Cell Cycle; Cell Division; Cell Nucleus; Cell Transformation, Neoplastic; DNA-Binding Proteins; Female; G1 Phase; Genes, Reporter; Genes, Tumor Suppressor; Humans; In Situ Nick-End Labeling; Kinetics; Mutagenesis, Site-Directed; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Smad4 Protein; Threonine; Trans-Activators; Transfection; Tumor Cells, Cultured

1999
Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells.
    The Journal of biological chemistry, 2000, Aug-18, Volume: 275, Issue:33

    Topics: Animals; Antibiotics, Antineoplastic; Cell Cycle; Cell Differentiation; Cell Division; Cell Size; Cell Transformation, Neoplastic; Culture Media, Serum-Free; Enzyme Activation; Enzyme Inhibitors; Hematopoietic Stem Cells; Humans; Insulin Receptor Substrate Proteins; Interleukin-3; Liver; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Okadaic Acid; Peroxidase; Phenotype; Phosphoproteins; Phosphorylation; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; Spleen; Threonine; Time Factors; Transfection; Tumor Cells, Cultured

2000
Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation.
    Genes & development, 2000, Dec-15, Volume: 14, Issue:24

    Topics: Active Transport, Cell Nucleus; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogenicity Tests; Carrier Proteins; Cell Nucleus; Cell Transformation, Neoplastic; Cyclin D1; Cytoplasm; Exportin 1 Protein; Fatty Acids, Unsaturated; Fibroblasts; Glycogen Synthase Kinase 3; Humans; Karyopherins; Male; Mice; Mice, SCID; Phosphorylation; Receptors, Cytoplasmic and Nuclear; S Phase; Threonine

2000
Elevation of a threonine phospholipid in polyoma virus transformed hamster embryo fibroblasts.
    Biochemical and biophysical research communications, 1977, Apr-11, Volume: 75, Issue:3

    Topics: Cell Line; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; Dinitrofluorobenzene; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Polyomavirus; Threonine; Trinitrobenzenesulfonic Acid

1977
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine

1970
Attachment and eclipse of adenovirus.
    Journal of virology, 1967, Volume: 1, Issue:5

    Topics: Adenoviridae; Carbon Isotopes; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Culture Techniques; Cytopathogenic Effect, Viral; Dactinomycin; Humans; Mouth Neoplasms; Phosphorus Isotopes; Puromycin; Threonine; Viral Proteins; Virus Replication

1967