Compounds > threonine

threonine and Breast Neoplasms

threonine has been researched along with Breast Neoplasms in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.92)18.7374
1990's5 (9.80)18.2507
2000's21 (41.18)29.6817
2010's18 (35.29)24.3611
2020's5 (9.80)2.80

Authors

AuthorsStudies
Cao, LQ; Gao, YH; Qu, SS; Yao, M1
Li, DQ; Liu, GY; Liu, HY; Liu, YY; Lu, Q; Shao, ZM; Yu, TJ; Zhang, FL1
Davey, NE; de Curtis, I; Lamarca, A; Ripamonti, M; Surini, S; Tonoli, D1
Almeida, MAP; Batista, AA; Campos, VNS; das Chagas Alves Lima, F; de Azevedo Dos Santos, APS; de Sousa, IH; Leite, CM; Lopes, AJO; Maciel-Silva, VL; Mourão, PS; Pereira, SRF; Vale, AAM1
Cho, JW; Ji, S; Kang, MJ; Kim, E; Kim, YJ; Kweon, TH; Park, YS; Yang, WH; Yi, EC1
Hayes, DF; Henry, NL; Hertz, DL; Kim, JH; Smith, EML; Stringer, KA; Sun, Y; Vangipuram, K; Yeomans, L1
Anwar, T; Arellano-Garcia, C; Basrur, V; Chen, YC; Gonzalez, ME; Grigsby, S; Kidwell, KM; Kim, HS; Kleer, CG; Muntean, A; Nesvizhskii, AI; Nikolovska-Coleska, Z; Ropa, J; Yoon, E1
Li, H; Liang, L; Liu, Z; Lu, J; Niu, Y; Shen, L; Shi, Z; Wang, M; Xu, X; Yan, Y; Yu, Y; Zhang, H; Zhao, Y1
Dashti, S; Ghafouri-Fard, S; Keshtkar, A; Taherian-Esfahani, Z1
Chen, CP; Guo, ZQ; Lu, N; Lü, QS; Tang, ZY; Wang, W; Wang, Z; Wen, XW; Wu, WX; Yang, HJ; Zhang, Y; Zhang, YP1
Branson, OE; Chaney, SB; Cheney, CM; Freitas, MA; Harshman, SW; Hoover, ME; Huang, C; Huebner, K; Rosol, TJ; Shapiro, CL; Wysocki, VH1
Bahl, M; Barnes, T; Bell, K; Califaretti, N; Campbell, C; DiSebastiano, KM; Dubin, JA; Hanning, R; Mourtzakis, M; Russell, C; Vance, V1
Anastasiadis, PZ; Copland, JA; Huveldt, D; Kourtidis, A; Yanagisawa, M1
Banerjee, S; Dixon, JE; Guo, X; Huang, L; Wang, X; Wang, Z; Yang, J1
Clevenger, CV; Harrington, KM1
Kawasaki, Y; Kishi, H; Muraguchi, A; Narita, K; Ozawa, T; Park, CM; Sakimura, A; Sakurai, H; Tanaka, T; Tomaru, R; Zhou, Y1
Cheng, C; Li, J; Rodriguez, Y; Wong, EYM; Xu, CY; Xu, PX; Zeng, L; Zhou, MM1
Cybulska, P; Eccles, LA; Jelinic, P; Levine, DA; Powell, SN; Tseng, J; Wielgos, M1
Berndt, N; Blaskovich, MA; Bucher, C; Carie, A; Carrico, D; Hamilton, A; Kazi, A; Moulder, S; Peng, H; Pledger, WJ; Pusateri, E; Sebti, SM; Thai, V1
Liu, Y; Moss, NM; Munshi, HG; Stack, MS; Wu, YI1
Brady, SN; Gwinn, AS; Maggi, LB; Pelletier, CL; Toso, EA; Weber, JD; Winkeler, CL1
Cho, S; Kim, HJ; Kim, SJ; Lee, DH; Lee, JA; Park, BC; Park, JE; Park, SG; Uchida, C; Uchida, T1
Danko, J; Horton, K; Kostyal, D; Lanning, C; Shay, T; Welt, RS; Welt, S1
Ruan, Y; Wang, H; Wei, H; Wei, X; Xu, L; Yu, M; Zhang, L1
Akoka, S; Giraudeau, P; Martineau, E; Tea, I1
Doucette, CD; Hilchie, AL; Hoskin, DW; Liwski, R1
Arteaga, CL; Bakin, AV; Baselga, J; Rojo, F; Shin, I; Shin, NY; Yakes, FM1
Beniston, R; Catzavelos, C; Ciarallo, S; Connor, MK; Franssen, E; Han, K; Kotchetkov, R; Lee, JH; Liang, J; Petrocelli, T; Slingerland, JM; Zubovitz, J1
Bellacosa, A; Bruni, P; Califano, D; Chiappetta, G; D'Alessio, A; Fusco, A; Melillo, RM; Motti, ML; Santoro, M; Tsichlis, P; Viglietto, G; Vinci, F1
Li, Q; Liu, B; Ma, X; Shen, S; Song, Z1
LORINCZ, AB; RYAN, WL1
Alqawi, O; Bates, S; Georges, E1
Chen, JS; Hung, MC; Lee, DF; Liao, Y; Sun, PR; Xia, W; Zhou, BP; Zhou, X1
Califano, D; De Marco, C; Fusco, A; Motti, ML; Viglietto, G1
Evans, DR; Guy, HI; Kotsis, DH; Serre, V; Sigoillot, FD; Sigoillot, SM1
Gil-Henn, C; Levitin, F; Prokocimer, Z; Rubinstein, DB; Smorodinsky, NI; Stern, O; Weiss, M; Wreschner, DH; Ziv, R1
Claret, FX; Johnson, TJ; Korapati, AL; Mansouri, A; Tian, L; Zhang, Q1
Adachi, S; Itamochi, H; Sudo, T; Takahashi, T; Tamamori-Adachi, M; Ueno, NT; Yamasaki, F1
Hays, AP; He, CZ; Mitsumoto, H; Naini, A; Rowland, LP1
Ethier, SP; Moffa, AB1
Callies, R; Frey, UH; Kimmig, R; Otterbach, F; Schmid, KW; Schmitz, KJ; Siffert, W; Wreczycki, C1
Altshuler, D; Bell, DW; Daly, MB; Freedman, ML; Garber, JE; Godwin, AK; Haber, DA; Haiman, CA; Harris, PL; Haserlat, SM; Henderson, BE; Kim, SH; Le Marchand, L; Niendorf, KB; Olopade, OI; Schiripo, TA; Sgroi, DC; Smith, MR; Wahrer, DC1
Chen, J; Huang, X; Li, D; Liu, R; Song, L; Zhou, H1
Amable, L; Aragon, IV; Golden, T; Honkanen, RE; Rutland, B; Samant, RS; Shevde, LA; Skarra, D; Tucker, JA; Zhou, G1
Blümich, B; Just, M; Mitze, M; Speckter, H; Thelen, M; Trömel, U1
Cunningham, A; Lazo, JS; Rice, RL; Wipf, P1
Bansal, RK; Dai, JL; Kern, SE1
Altiok, N; Altiok, S; Avraham, H; Batt, D; Downward, J; Papautsky, A; Roberts, TM1
Takahashi, K1
Hitch, DC; Kubota, A; Meguid, MM1
Horn, D; Kallestad, JC; Linsley, PS1

Reviews

1 review(s) available for threonine and Breast Neoplasms

ArticleYear
Associations between XRCC3 Thr241Met polymorphisms and breast cancer risk: systematic-review and meta-analysis of 55 case-control studies.
    BMC medical genetics, 2019, 05-10, Volume: 20, Issue:1

    Topics: Breast Neoplasms; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Homologous Recombination; Humans; Methionine; Polymorphism, Single Nucleotide; Threonine

2019

Other Studies

50 other study(ies) available for threonine and Breast Neoplasms

ArticleYear
TTK predicts triple positive breast cancer prognosis and regulates tumor proliferation and invasion.
    Neoplasma, 2022, Volume: 69, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Prognosis; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Threonine; Tyrosine

2022
O-GlcNAcylation of MORC2 at threonine 556 by OGT couples TGF-β signaling to breast cancer progression.
    Cell death and differentiation, 2022, Volume: 29, Issue:4

    Topics: Breast Neoplasms; Female; Humans; N-Acetylglucosaminyltransferases; Threonine; Transcription Factors; Transforming Growth Factor beta1

2022
A functional interaction between liprin-α1 and B56γ regulatory subunit of protein phosphatase 2A supports tumor cell motility.
    Communications biology, 2022, 09-28, Volume: 5, Issue:1

    Topics: Breast Neoplasms; Cell Movement; Female; Holoenzymes; Humans; Protein Phosphatase 2; Serine; Threonine

2022
Ruthenium (II) complexes with N, O-chelating proline and threonine ligands cause selective cytotoxicity by the induction of genomic instability, cell cycle arrest and apoptosis in breast and prostate tumor cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 62

    Topics: Amino Acid Transport System ASC; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Chelating Agents; DNA Damage; Female; Genomic Instability; Humans; Ligands; Male; Minor Histocompatibility Antigens; Molecular Docking Simulation; Proline; Prostatic Neoplasms; Ruthenium Compounds; Threonine

2020
O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation.
    Scientific reports, 2020, 11-16, Volume: 10, Issue:1

    Topics: Acetylglucosamine; Breast Neoplasms; Female; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Protein Processing, Post-Translational; Proteolysis; Serine; Signal Transduction; Smad4 Protein; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Ubiquitin

2020
Pharmacometabolomics reveals a role for histidine, phenylalanine, and threonine in the development of paclitaxel-induced peripheral neuropathy.
    Breast cancer research and treatment, 2018, Volume: 171, Issue:3

    Topics: Adult; Aged; Biomarkers; Breast Neoplasms; Female; Histidine; Humans; Magnetic Resonance Spectroscopy; Metabolomics; Middle Aged; Paclitaxel; Peripheral Nervous System Diseases; Phenylalanine; Threonine

2018
p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis.
    Nature communications, 2018, 07-18, Volume: 9, Issue:1

    Topics: Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Lung Neoplasms; Mice; Mice, SCID; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polycomb Repressive Complex 2; RNA, Small Interfering; Survival Analysis; Threonine

2018
Delanzomib, a novel proteasome inhibitor, sensitizes breast cancer cells to doxorubicin-induced apoptosis.
    Thoracic cancer, 2019, Volume: 10, Issue:4

    Topics: Boronic Acids; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; MCF-7 Cells; Phosphorylation; Proteasome Inhibitors; Threonine; Tumor Suppressor Protein p53

2019
[Expression of SKP2 and Thr187 phosphorylated p27(kip1) proteins in human breast carcinoma and their prognostic significance].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2013, Volume: 42, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Carcinoma; Cyclin-Dependent Kinase Inhibitor p27; Female; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Phosphorylation; Prognosis; S-Phase Kinase-Associated Proteins; Threonine

2013
Histone H1 phosphorylation in breast cancer.
    Journal of proteome research, 2014, May-02, Volume: 13, Issue:5

    Topics: Amino Acid Sequence; Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromatography, Liquid; Chromones; Enzyme Inhibitors; Estradiol; Female; Histones; Humans; Immunohistochemistry; Mass Spectrometry; MCF-7 Cells; Molecular Sequence Data; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Isoforms; Proteomics; Threonine

2014
Plasma amino acid profiles of breast cancer patients early in the trajectory of the disease differ from healthy comparison groups.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2014, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Amino Acids; Body Composition; Breast Neoplasms; Case-Control Studies; Energy Intake; Female; Glutamic Acid; Glutamine; Histidine; Humans; Leucine; Middle Aged; Threonine

2014
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Renal Cell; Catenins; Cell Transformation, Neoplastic; Delta Catenin; Female; Humans; Immunoenzyme Techniques; Immunoprecipitation; Kidney Neoplasms; Phosphoproteins; Phosphorylation; Protein Binding; Serine; Threonine; Tissue Array Analysis; Tumor Cells, Cultured; Tyrosine

2015
Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis.
    Nature cell biology, 2016, Volume: 18, Issue:2

    Topics: Animals; ATPases Associated with Diverse Cellular Activities; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; CRISPR-Cas Systems; Dyrk Kinases; Female; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Mice, Nude; Phosphorylation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteolysis; RNA Interference; Signal Transduction; Threonine; Time Factors; Transfection; Tumor Burden

2016
Identification of NEK3 Kinase Threonine 165 as a Novel Regulatory Phosphorylation Site That Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration.
    The Journal of biological chemistry, 2016, Oct-07, Volume: 291, Issue:41

    Topics: Amino Acid Substitution; Breast Neoplasms; Cell Movement; Enzyme Activation; Female; Humans; MAP Kinase Signaling System; MCF-7 Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation, Missense; Neoplasm Proteins; NIMA-Related Kinases; Phosphorylation; Prolactin; Threonine

2016
Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain.
    Scientific reports, 2016, 08-17, Volume: 6

    Topics: Breast Neoplasms; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Female; HEK293 Cells; Humans; Multienzyme Complexes; Phosphorylation; Protein Domains; Receptor, ErbB-2; Receptor, ErbB-3; Threonine

2016
EYA1's Conformation Specificity in Dephosphorylating Phosphothreonine in Myc and Its Activity on Myc Stabilization in Breast Cancer.
    Molecular and cellular biology, 2017, 01-01, Volume: 37, Issue:1

    Topics: Breast Neoplasms; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Models, Molecular; Nuclear Proteins; Phosphorylation; Protein Binding; Protein Conformation; Protein Stability; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-myc; Threonine; Ubiquitin-Protein Ligases

2017
The EMSY threonine 207 phospho-site is required for EMSYdriven suppression of DNA damage repair.
    Oncotarget, 2017, Feb-21, Volume: 8, Issue:8

    Topics: Breast Neoplasms; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA Repair; Female; Humans; Immunoblotting; Immunoprecipitation; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Phosphorylation; Real-Time Polymerase Chain Reaction; Repressor Proteins; Threonine

2017
Blockade of protein geranylgeranylation inhibits Cdk2-dependent p27Kip1 phosphorylation on Thr187 and accumulates p27Kip1 in the nucleus: implications for breast cancer therapy.
    Molecular and cellular biology, 2009, Volume: 29, Issue:8

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Female; Humans; Mice; NIH 3T3 Cells; Phosphorylation; Protein Prenylation; Threonine

2009
Modulation of the membrane type 1 matrix metalloproteinase cytoplasmic tail enhances tumor cell invasion and proliferation in three-dimensional collagen matrices.
    The Journal of biological chemistry, 2009, Jul-24, Volume: 284, Issue:30

    Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen Type I; Cytoplasm; Humans; Matrix Metalloproteinase 14; Molecular Sequence Data; Phosphorylation; Point Mutation; Rats; Threonine

2009
Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation.
    Oncogene, 2009, Sep-10, Volume: 28, Issue:36

    Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Female; Green Fluorescent Proteins; HeLa Cells; Humans; Immunohistochemistry; Male; Mice; Mice, Knockout; Mutation; NIH 3T3 Cells; Nuclear Proteins; Nucleophosmin; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-mdm2; RNA Interference; Threonine; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53

2009
A critical step for JNK activation: isomerization by the prolyl isomerase Pin1.
    Cell death and differentiation, 2012, Volume: 19, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Female; Gene Expression Regulation; HEK293 Cells; HeLa Cells; Humans; Jurkat Cells; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 8; NIMA-Interacting Peptidylprolyl Isomerase; Oxidative Stress; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Protein Conformation; Proteolysis; Subtilisin; Threonine; Tyrosine

2012
Trastuzumab and lapatinib modulation of HER2 tyrosine/threonine phosphorylation and cell signaling.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:3

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Female; Humans; Lapatinib; Phosphorylation; Quinazolines; Receptor, ErbB-2; Signal Transduction; Threonine; Trastuzumab; Tyrosine

2012
Monocillin II inhibits human breast cancer growth partially by inhibiting MAPK pathways and CDK2 Thr160 phosphorylation.
    Chembiochem : a European journal of chemical biology, 2012, Feb-13, Volume: 13, Issue:3

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; HeLa Cells; Humans; Lactones; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Phosphorylation; Structure-Activity Relationship; Threonine; Tumor Cells, Cultured

2012
Absolute quantification of metabolites in breast cancer cell extracts by quantitative 2D (1) H INADEQUATE NMR.
    NMR in biomedicine, 2012, Volume: 25, Issue:8

    Topics: Breast Neoplasms; Cell Differentiation; Cell Extracts; Cell Line, Tumor; Female; Humans; Intracellular Space; Metabolome; Metabolomics; Models, Biological; Nuclear Magnetic Resonance, Biomolecular; Principal Component Analysis; Protons; Reference Standards; Threonine

2012
Piperine, a dietary phytochemical, inhibits angiogenesis.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1

    Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Aorta; Benzodioxoles; Breast Neoplasms; Cell Movement; Cell Proliferation; Chick Embryo; Chromones; Drug Screening Assays, Antitumor; Female; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Morpholines; Neovascularization, Pathologic; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Rats, Wistar; S Phase; Serine; Threonine; TRPV Cation Channels

2013
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
    Nature medicine, 2002, Volume: 8, Issue:10

    Topics: Breast Neoplasms; Carcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Fractionation; Cell Line; Cell Nucleus; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; Female; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Threonine; Tumor Suppressor Proteins

2002
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.
    Nature medicine, 2002, Volume: 8, Issue:10

    Topics: Active Transport, Cell Nucleus; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Line; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; Female; G1 Phase; Humans; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Survival Rate; Threonine; Transforming Growth Factor beta; Tumor Suppressor Proteins

2002
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
    Nature medicine, 2002, Volume: 8, Issue:10

    Topics: Breast Neoplasms; Cell Cycle Proteins; Cell Line; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; Female; Genes, Tumor Suppressor; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Threonine; Tumor Suppressor Proteins

2002
[Distinctive infrared spectral features in human breast cancer].
    Guang pu xue yu guang pu fen xi = Guang pu, 2000, Volume: 20, Issue:1

    Topics: Breast Neoplasms; Female; Glycogen; Humans; Spectroscopy, Fourier Transform Infrared; Threonine; Tyrosine

2000
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine

1964
Arginine482 to threonine mutation in the breast cancer resistance protein ABCG2 inhibits rhodamine 123 transport while increasing binding.
    The Biochemical journal, 2004, Sep-01, Volume: 382, Issue:Pt 2

    Topics: Amino Acid Substitution; Arginine; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Humans; Mutation, Missense; Neoplasm Proteins; Protein Binding; Rhodamine 123; Threonine

2004
Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-01, Volume: 10, Issue:11

    Topics: Adult; Breast Neoplasms; Cell Cycle Proteins; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cytoplasm; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; In Situ Hybridization, Fluorescence; Lymphatic Metastasis; Middle Aged; Multivariate Analysis; Phosphorylation; Prognosis; Proportional Hazards Models; Receptor, ErbB-2; Threonine; Time Factors

2004
Akt-dependent T198 phosphorylation of cyclin-dependent kinase inhibitor p27kip1 in breast cancer.
    Cell cycle (Georgetown, Tex.), 2004, Volume: 3, Issue:8

    Topics: Amino Acid Sequence; Breast; Breast Neoplasms; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Activation; Epithelial Cells; Humans; Kidney; Molecular Sequence Data; Phosphates; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Threonine; Tumor Suppressor Proteins

2004
Nuclear localization and mitogen-activated protein kinase phosphorylation of the multifunctional protein CAD.
    The Journal of biological chemistry, 2005, Jul-08, Volume: 280, Issue:27

    Topics: Active Transport, Cell Nucleus; Animals; Aspartate Carbamoyltransferase; Breast Neoplasms; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Division; Cell Fractionation; Cell Line, Tumor; Cell Nucleus; Cricetinae; Cytoplasm; Dihydroorotase; Dihydroorotate Dehydrogenase; Epidermal Growth Factor; Fluorescent Antibody Technique; Humans; Kidney; Microscopy, Confocal; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Mutagenesis, Site-Directed; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Oxidoreductases Acting on CH-CH Group Donors; Phosphorylation; Pyrimidines; Threonine

2005
The MUC1 SEA module is a self-cleaving domain.
    The Journal of biological chemistry, 2005, Sep-30, Volume: 280, Issue:39

    Topics: Agrin; Alternative Splicing; Amino Acid Sequence; Amino Acid Substitution; Animals; Antigens; Antigens, Neoplasm; Base Sequence; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cysteine; Enteropeptidase; Enzyme-Linked Immunosorbent Assay; Female; Glycoproteins; Humans; Hydrolysis; Hydroxylamine; Male; Mice; Models, Biological; Molecular Sequence Data; Mucin-1; Mucins; Protein Isoforms; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sea Urchins; Spermatozoa; Threonine

2005
Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.
    FEBS letters, 2005, Jul-18, Volume: 579, Issue:18

    Topics: Adenoviridae; Alanine; Annexin A5; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Doxycycline; Ecdysterone; Humans; Immunoblotting; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Prognosis; Proteasome Endopeptidase Complex; Proteins; S Phase; Threonine; Time Factors; Tumor Suppressor Proteins; Ubiquitin

2005
Cyclin A-associated kinase activity is needed for paclitaxel sensitivity.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; CDC2 Protein Kinase; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Threonine; Transfection; Tumor Cells, Cultured

2005
Sporadic amyotrophic lateral sclerosis and breast cancer: Hyaline conglomerate inclusions lead to identification of SOD1 mutation.
    Journal of the neurological sciences, 2006, Mar-15, Volume: 242, Issue:1-2

    Topics: Aged; Amyotrophic Lateral Sclerosis; Breast Neoplasms; DNA Mutational Analysis; Female; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Isoleucine; Nerve Degeneration; Superoxide Dismutase; Superoxide Dismutase-1; Threonine

2006
Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells.
    Journal of cellular physiology, 2007, Volume: 210, Issue:3

    Topics: Alternative Splicing; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial Cells; Female; Fibroblast Growth Factor 7; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Mammary Glands, Human; Protein Isoforms; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction; Threonine

2007
The T393C polymorphism in the gene GNAS1 of G protein is associated with survival of patients with invasive breast carcinoma.
    Breast cancer research and treatment, 2007, Volume: 105, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromogranins; Cysteine; Female; GTP-Binding Protein alpha Subunits, Gs; Humans; Middle Aged; Neoplasm Invasiveness; Polymorphism, Single Nucleotide; Survival Rate; Threonine

2007
Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.
    International journal of cancer, 2007, Dec-15, Volume: 121, Issue:12

    Topics: Adult; Age of Onset; Aged; Asian People; Black or African American; Breast Neoplasms; Case-Control Studies; Checkpoint Kinase 2; DNA Mutational Analysis; DNA, Complementary; Female; Gene Frequency; Genetic Predisposition to Disease; Germ-Line Mutation; Hawaii; Hispanic or Latino; Histidine; Humans; Isoleucine; Leucine; Male; Middle Aged; Mutation; Mutation, Missense; Predictive Value of Tests; Proline; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Risk Assessment; Risk Factors; Threonine; Tyrosine; United States; White People

2007
Thr11 phosphorylated H3 is associated with centromere DNA during mitosis in MCF-7 cells.
    Molecular and cellular biochemistry, 2008, Volume: 311, Issue:1-2

    Topics: Breast Neoplasms; Cell Line, Tumor; Centromere; DNA; Female; Histones; Humans; Mitosis; Threonine

2008
Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer.
    Biochimica et biophysica acta, 2008, Volume: 1782, Issue:4

    Topics: Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Death; Cell Line, Tumor; Doxorubicin; Humans; Mice; Mice, Nude; Nuclear Proteins; Oxidative Stress; Phosphoprotein Phosphatases; Threonine; Time Factors; Ultraviolet Rays; Up-Regulation; Vinblastine

2008
[In vitro NMR spectroscopy of healthy, pathologically changed and carcinomatous breast tissue samples correlated with histological findings].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1994, Volume: 161, Issue:2

    Topics: Breast; Breast Diseases; Breast Neoplasms; Diagnosis, Differential; Fatty Acids; Female; Glucose; Glycine; Humans; In Vitro Techniques; Inositol; Magnetic Resonance Spectroscopy; Serine; Sucrose; Threonine

1994
Combinatorial synthesis and biological evaluation of library of small-molecule Ser/Thr-protein phosphatase inhibitors.
    Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:1

    Topics: Breast Neoplasms; Cell Cycle; Cell Division; Drug Design; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Marine Toxins; Mass Spectrometry; Oxazoles; Phosphoprotein Phosphatases; Serine; Threonine; Tumor Cells, Cultured

1997
G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Feb-16, Volume: 96, Issue:4

    Topics: Amino Acid Substitution; Apoptosis; Arginine; Breast Neoplasms; Cell Cycle; Cell Division; Cell Nucleus; Cell Transformation, Neoplastic; DNA-Binding Proteins; Female; G1 Phase; Genes, Reporter; Genes, Tumor Suppressor; Humans; In Situ Nick-End Labeling; Kinetics; Mutagenesis, Site-Directed; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Smad4 Protein; Threonine; Trans-Activators; Transfection; Tumor Cells, Cultured

1999
Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells.
    The Journal of biological chemistry, 1999, Nov-05, Volume: 274, Issue:45

    Topics: BRCA1 Protein; Breast Neoplasms; Female; Humans; Neuregulin-1; Nuclear Localization Signals; Phosphatidylinositol 3-Kinases; Phosphorylation; Threonine; Tumor Cells, Cultured

1999
The linkage between beta1 integrin and the actin cytoskeleton is differentially regulated by tyrosine and serine/threonine phosphorylation of beta1 integrin in normal and cancerous human breast cells.
    BMC cell biology, 2001, Volume: 2

    Topics: Actin Cytoskeleton; Actinin; Actins; Amino Acid Sequence; Breast; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Epithelial Cells; Female; Humans; Integrin beta1; Molecular Sequence Data; Phosphorylation; Precipitin Tests; Serine; Threonine; Tumor Cells, Cultured; Tyrosine

2001
Amino acid profiles correlate diagnostically with organ site in three kinds of malignant tumors.
    Cancer, 1992, May-01, Volume: 69, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Arginine; Breast Neoplasms; Carcinoma, Squamous Cell; Discriminant Analysis; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Male; Middle Aged; Sex Factors; Threonine

1992
Biosynthesis of high molecular weight breast carcinoma associated mucin glycoproteins.
    The Journal of biological chemistry, 1988, Jun-15, Volume: 263, Issue:17

    Topics: Antibodies, Monoclonal; Breast Neoplasms; Densitometry; Electrophoresis, Polyacrylamide Gel; Female; Glycosylation; Half-Life; Humans; Molecular Weight; Mucins; Proline; Threonine

1988