threonine and Benign Neoplasms

threonine has been researched along with Benign Neoplasms in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (8.33)	18.7374
1990's	2 (3.33)	18.2507
2000's	16 (26.67)	29.6817
2010's	28 (46.67)	24.3611
2020's	9 (15.00)	2.80

Authors

Authors	Studies
Evan Prince, S; Panchal, NK	1
Daigo, Y; Haba, R; Hirata, M; Ito, H; Kanaji, N; Kaneko, MK; Kaneko, S; Kato, Y; Kishida, T; Kojima, M; Kontani, K; Machitani, M; Masaki, T; Masutomi, K; Matsuda, Y; Minamoto, T; Miyagi, Y; Miyatake, N; Morinaga, S; Mukai, Y; Okano, K; Oshima, T; Takei, J; Yamada, S; Yamakawa, K; Yamashita, T; Yasukawa, M; Ye, J; Yokose, T	1
Liu, R; Luo, H; Ma, Y; Wang, X; Zhang, H; Zhang, Q	1
Anwar, S; Hasan, GM; Hassan, MI; Islam, A; Shahwan, M	1
Chen, F; Li, S; Liu, H; Liu, J; Lv, L; Shao, H; Tang, R; Yu, C; Yuan, K; Zhang, J; Zhang, Q	1
Gao, Y; Li, L; Li, Y; Xiu, M	1
Almilaibary, A	1
Ding, D; Hou, X; Huang, H; Jimenez, R; Shi, L; Tian, Y; Wang, L; Weroha, SJ; Zheng, R	1
Mi, YY; Song, NH; Wang, ZJ; Yuan, W; Zhang, LF; Zhang, W; Zhu, LJ; Zuo, L	1
Abdulkadir, SA; Anker, JF; Chakravarti, D; Chalmers, ZR; Han, H; Izquierdo-Ferrer, J; Jain, AD; Kandela, I; Luan, Y; Lysy, B; Mishra, RK; Mok, H; Parker, JB; Rodriguez, Y; Sagar, V; Schiltz, GE; Truica, MI; Unno, K; Vatapalli, R; Yoo, YA	1
Abe, T; Ando, Y; Furuta, Y; Hayashizaki, Y; Kaneko, MK; Kaneko, S; Kato, Y; Kawaji, H; Kondo, T; Machitani, M; Masutomi, K; Matsuda, Y; Morioka, MS; Shiozawa, K; Shirouzu, M; Shoji, S; Yamada, S; Yamashita, T; Yasukawa, M	1
An, H; Hong, E; Kang, JM; Kim, P; Kim, SJ; Kwak, MK; Lee, J; Lee, S; Ooshima, A; Pang, K; Park, J; Park, S; Park, Y; Sun, EJ; Yang, KM	1
Antonia, RJ; Baldwin, AS	1
Fukuda, H; Kazuma, Y; Kobayashi, M; Koyabu, S; Maruyama, W; Matsui, H; Matsumoto, T; Morishita, R; Nagata, K; Sarca, AD; Sato, H; Shindo, K; Shirakawa, K; Takaori-Kondo, A; Tanabe, F; Yamazaki, H; Yokoyama, M	1
Cui, D; Feng, S; Fu, Y; Hou, Q; Li, J; Liu, L; Liu, W; Luo, Y; Shi, H; Zhang, P	1
Hu, Y; Wu, P; Zhang, J	1
Huang, G; Huang, L; Liu, J; Miao, P; Song, S; Sun, X; Xie, L; Yang, F; Yu, Z; Zhang, T; Zhao, L; Zhao, X	1
Singh, JP; Wu, J; Yang, X; Zhang, K	1
Archakov, AI; Chernobrovkin, AL; Gorshkov, MV; Ilina, IY; Ivanov, MV; Karpov, DS; Karpova, MA; Kopylov, AT; Kuznetsova, KG; Moshkovskii, SA; Moysa, AA; Pyatnitskiy, MA; Veselovsky, AV; Zgoda, VG	1
Chen, Q; Li, C; Li, D; Ren, J; Wang, Q; Wu, M; Zhang, Y	1
Hahlbrock, A; Jung, S; Knauer, SK; Schilling, O; Schirmeister, T; Stauber, RH; van den Boom, J; Wünsch, D	1
Abhijit, S; Chopra, C; Jagadeeshan, S; Kanumuri, R; Kumar, A; Muthuswamy, B; Nair, AS; Ramanathan, K; Rayala, SK; Shankar Pitani, R; Singhal, M; Srinivasan, S; Sundaram, S; Surabhi, RP; Tentu, S; Venkatraman, G	1
Balyan, R; Basu, S; Bhatt, K; Borde, L; Bose, A; Dalal, SN; Gulvady, A; Hosing, AS; Kundu, TK; Mukhopadhyay, A; Sehgal, L; Senapati, P; Thorat, R	1
Kłoczko, J; Ołdziej, AE; Romaniuk, W; Zińczuk, J	1
Pacini, S; Reinwald, H; Ruggiero, M	1
Sakurai, H	1
Cepeda, D; Klotz, K; Sangfelt, O; Spruck, C; Sun, D; Tan, Y	1
Bae, CD; Hong, KM; Hong, KU; Kim, HJ; Kim, HS; Park, J; Seong, YS	1
Aoki, M; Deguchi, A; Kojima, Y; Miyoshi, H; Okawa, K; Taketo, MM	1
Bagnati, R; Cereda, R; D'Incalci, M; Livi, V; Marangon, E; Sala, F; Zucchetti, M	1
Kim, YS; Mollapour, M; Neckers, L; Trepel, J; Tsutsumi, S	1
Kay, LE; Ruschak, AM; Schimmer, AD; Slassi, M	1
Csaderova, L; Dequiedt, F; Ditte, P; Hulikova, A; Kopacek, J; Ohradanova-Repic, A; Pastorek, J; Pastorekova, S; Supuran, CT; Svastova, E; Zatovicova, M	1
Backendorf, C; Florea, BI; Lanz, HL; Noteborn, MH	1
Bao, YL; Fan, C; Huang, YX; Li, YX; Li, YY; Song, ZB; Sun, LG; Sun, Y; Wang, GN; Wu, P; Wu, Y; Yu, CL; Zhang, Y; Zheng, LH	1
Castilla, C; Giráldez, S; Herrero-Ruiz, J; Japón, MÁ; Limón-Mortés, MC; Mora-Santos, M; Romero, F; Sáez, C; Tortolero, M	1
de Giuseppe, PO; dos Santos, CR; Martins, NH; Meza, AN; Murakami, MT; Pereira, HD	1
Böhm, S; Brunelli, D; Cereda, R; D'Incalci, M; De Braud, F; Delmonte, A; Driessen, C; Gallerani, E; Hess, D; Marangon, E; Marsoni, S; Martinelli, G; Noberasco, C; Sala, F; Sessa, C; Zucchetti, M	1
Eberwine, JH; Kim, MS; Klein-Szanto, AJ; Morris, JF; Rustgi, A; Schochet, T; Sul, JY	1
Irie, K; Masuda, A; Miyasaka, K; Ohigashi, H; Saito, N; Shindo, M; Shirai, Y	1
Conti, CJ; Fox, SR; Giesting, S; Knudsen, ES; Lambeck, TC; Lan, Z; Senderowicz, AM; Solomon, DA; Wang, Y	1
Altieri, DC	1
GENTY, N; MELONI, GA; VENDRELY, R	1
LORINCZ, AB; RYAN, WL	1
Aratani, Y; Furuhata, A; Kawai, Y; Toyokuni, S; Uchida, K	1
Gallick, GE; Kim, LS; Minard, ME; Price, JE	1
Arnold, H; Chasse, D; Counter, CM; Cunningham, M; Hahn, WC; Ivaldi, G; Means, AR; Monteith, T; Nevins, JR; Sears, R; Shenolikar, S; Stukenberg, PT; Uchida, T; Yeh, E	1
Benzeno, S; Diehl, JA	1
Byrski, T; Castaneda, J; Cybulski, C; Debniak, B; Debniak, T; Górski, B; Huzarski, T; Jaworowska, E; Klujszo-Grabowska, E; Kurzawski, G; Lener, M; Lubinski, J; Masojc, B; Matyjasik, J; Medrek, K; Mierzejewski, M; Narod, S; Nej-Wołosiak, K; Oszurek, O; Oszutowska, D; Rozmiarek, A; Scott, RJ; Suchy, J; Szymańska, A; Szymańska, J; Teodorczyk, U; van de Wetering, T; Złowocka, E	1
Binni, F; Carta, C; Celli, P; Cordisco, EL; Di Rocco, C; Dominici, C; Flex, E; Genuardi, M; Grammatico, P; Martinelli, S; McDowell, HP; Moretti, S; Picardo, M; Pinchera, A; Puxeddu, E; Riccardi, R; Rosolen, A; Sorcini, M; Tartaglia, M; Tonacchera, M	1
Basbous, J; Chalbos, D; Hipskind, R; Jariel-Encontre, I; Piechaczyk, M	1
Algar, U; Blokhuis, MM; Goldberg, PA; Govender, D; Pietersen, GE; Ramesar, RS; Vorster, AA	1
Allievi, C; Berkers, C; Bernareggi, A; Bussolati, B; Camussi, G; Cassin, M; Coscia, M; Costa, G; de Feudis, P; di Giovine, S; Ferracini, R; Ferrero, D; Giai, V; Hunter, K; Inghirami, G; Jones-Bolin, S; Massaia, M; Neri, A; Nicoli, P; Ovaa, H; Palumbo, A; Peola, S; Pescalli, N; Pezzoni, G; Piva, R; Roato, I; Ruggeri, B; Strepponi, I; Tamagno, I; Williams, M; Zhao, H	1
Chinkers, M; Garbers, DL	1
Barnard, GF; Chen, LB; Puder, M; Staniunas, RJ; Steele, GD	1
Alarcon-Vargas, D; Bar-Shira, A; Buschmann, T; Fried, VA; Fuchs, SY; Gaarde, WA; Henderson, S; Holbrook, NJ; Ivanov, VN; Minamoto, T; Pincus, MR; Potapova, O; Ronai, Z; Shiloh, Y	1
Dittmann, KH; Mayer, C; Rodemann, HP	1
Nakajima, T; Tanaka, T	1
Nagao, M; Tahira, T	1
Björnesjö, KB	1

Reviews

12 review(s) available for threonine and Benign Neoplasms

Article	Year
The NEK family of serine/threonine kinases as a biomarker for cancer. Clinical and experimental medicine, 2023, Volume: 23, Issue:1 Topics: Biomarkers; Cell Cycle Proteins; Humans; Neoplasms; NIMA-Related Kinases; Protein Serine-Threonine Kinases; Serine; Threonine	2023
Microtubule-affinity regulating kinase 4: A potential drug target for cancer therapy. Cellular signalling, 2022, Volume: 99 Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Humans; Microtubules; Neoplasms; Neurodegenerative Diseases; NF-kappa B; Phosphates; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Serine; Threonine; TOR Serine-Threonine Kinases; Tyrosine	2022
A patent and literature review of CDK12 inhibitors. Expert opinion on therapeutic patents, 2022, Volume: 32, Issue:10 Topics: Animals; Cyclin-Dependent Kinases; Cyclins; Humans; Mice; Myotonic Dystrophy; Neoplasms; Patents as Topic; Protein Kinase Inhibitors; RNA, Messenger; Serine; Threonine	2022
An update regarding the role of WNK kinases in cancer. Cell death & disease, 2022, 09-19, Volume: 13, Issue:9 Topics: Alanine; Animals; Bicarbonates; Mammals; Neoplasms; Neovascularization, Pathologic; Proline; Serine; Sodium Chloride Symporters; Threonine	2022
Clinical and marketed proteasome inhibitors for cancer treatment. Current medicinal chemistry, 2013, Volume: 20, Issue:20 Topics: Boron Compounds; Boronic Acids; Bortezomib; Glycine; Humans; Lactones; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Structure-Activity Relationship; Threonine	2013
O-GlcNAc signaling in cancer metabolism and epigenetics. Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt A Topics: Acetylglucosamine; Antigens, Neoplasm; Cell Proliferation; Energy Metabolism; Epigenesis, Genetic; Glycosylation; Histone Acetyltransferases; Histones; Humans; Hyaluronoglucosaminidase; N-Acetylglucosaminyltransferases; Neoplasms; Protein Processing, Post-Translational; Serine; Signal Transduction; Threonine; Transcription Factors; Transcription, Genetic; Transcriptional Activation	2015
Taspase1: a 'misunderstood' protease with translational cancer relevance. Oncogene, 2016, 06-30, Volume: 35, Issue:26 Topics: Aspartate Ammonia-Lyase; Endopeptidases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Molecular Structure; Neoplasms; Threonine; Translational Research, Biomedical	2016
[Proteasome inhibitors in cancer therapy]. Postepy higieny i medycyny doswiadczalnej (Online), 2015, Dec-31, Volume: 69 Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspases; Dipeptides; Humans; Lactones; Multiple Myeloma; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Pyrroles; Thiazoles; Threonine	2015
Non-canonical Activation of Receptor Tyrosine Kinases in Cancer Progression. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2017, Volume: 137, Issue:2 Topics: Antineoplastic Agents; Cell Movement; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Phosphorylation; Receptor Protein-Tyrosine Kinases; Receptor, EphA2; Receptor, ErbB-2; Serine; Threonine	2017
Novel proteasome inhibitors to overcome bortezomib resistance. Journal of the National Cancer Institute, 2011, Jul-06, Volume: 103, Issue:13 Topics: Allosteric Site; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Chloroquine; Clioquinol; Drug Resistance, Neoplasm; Humans; Hydroxyquinolines; Lactones; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Threonine; Ubiquitinated Proteins; Ubiquitination	2011
A first in human phase I study of the proteasome inhibitor CEP-18770 in patients with advanced solid tumours and multiple myeloma. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2 Topics: Adult; Aged; Boronic Acids; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasms; Proteasome Inhibitors; Threonine	2013
The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression. Breast cancer research and treatment, 2004, Volume: 84, Issue:1 Topics: Animals; Apoptosis; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Disease Progression; GTP Phosphohydrolases; Guanine Nucleotide Exchange Factors; Humans; Mice; Neoplasm Invasiveness; Neoplasms; Phosphorylation; Proteins; rho GTP-Binding Proteins; Signal Transduction; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Threonine	2004

Trials

1 trial(s) available for threonine and Benign Neoplasms

Article	Year
A first in human phase I study of the proteasome inhibitor CEP-18770 in patients with advanced solid tumours and multiple myeloma. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2 Topics: Adult; Aged; Boronic Acids; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasms; Proteasome Inhibitors; Threonine	2013

Other Studies

48 other study(ies) available for threonine and Benign Neoplasms

Article	Year
Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs. The Journal of pathology, 2022, Volume: 257, Issue:2 Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Humans; Neoplasms; Phosphorylation; Prognosis; RNA-Dependent RNA Polymerase; Telomerase; Threonine	2022
A pancancer analysis of the carcinogenic role of receptor-interacting serine/threonine protein kinase-2 (RIPK2) in human tumours. BMC medical genomics, 2022, 04-26, Volume: 15, Issue:1 Topics: Carcinogenesis; Carcinogens; Humans; Neoplasms; NF-kappa B; Receptor-Interacting Protein Serine-Threonine Kinase 2; Serine; Threonine	2022
Targeting aurora kinase a (AURKA) in cancer: molecular docking and dynamic simulations of potential AURKA inhibitors. Medical oncology (Northwood, London, England), 2022, Sep-30, Volume: 39, Issue:12 Topics: Animals; Aurora Kinase A; Cell Line, Tumor; Humans; Mammals; Molecular Docking Simulation; Neoplasms; Piperazines; Serine; Thiazoles; Threonine	2022
Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer. Nature communications, 2022, 10-23, Volume: 13, Issue:1 Topics: Cell Cycle Proteins; Humans; Male; Neoplasms; Retinoblastoma Protein; Serine; Threonine; Transcription Factors	2022
MMP-8 C-799 T, Lys460Thr, and Lys87Glu variants are not related to risk of cancer. BMC medical genetics, 2019, 10-21, Volume: 20, Issue:1 Topics: Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Matrix Metalloproteinase 8; Neoplasms; Polymorphism, Single Nucleotide; Threonine	2019
Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer cell, 2019, 11-11, Volume: 36, Issue:5 Topics: Animals; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Cell Line, Tumor; Drug Discovery; Drug Resistance, Neoplasm; Drug Synergism; Feasibility Studies; Female; Humans; Male; Mice; Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Proteolysis; Proto-Oncogene Proteins c-myc; Threonine; Tumor Microenvironment; Up-Regulation; Xenograft Model Antitumor Assays	2019
CDK1 dependent phosphorylation of hTERT contributes to cancer progression. Nature communications, 2020, 03-25, Volume: 11, Issue:1 Topics: Animals; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Mice; Mitosis; Mutation; Neoplasms; Phosphorylation; RNA-Dependent RNA Polymerase; Telomerase; Threonine	2020
Galangin enhances TGF-β1-mediated growth inhibition by suppressing phosphorylation of threonine 179 residue in Smad3 linker region. Biochemical and biophysical research communications, 2017, 12-16, Volume: 494, Issue:3-4 Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; Cell Proliferation; Flavonoids; Humans; Neoplasms; Phosphorylation; Protein Binding; Smad3 Protein; Threonine; Transforming Growth Factor beta1; Treatment Outcome	2017
IKK promotes cytokine-induced and cancer-associated AMPK activity and attenuates phenformin-induced cell death in LKB1-deficient cells. Science signaling, 2018, 07-10, Volume: 11, Issue:538 Topics: A549 Cells; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Apoptosis; Cells, Cultured; Cytokines; HeLa Cells; Humans; I-kappa B Kinase; Mice, Knockout; Neoplasms; Phenformin; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Threonine	2018
Protein kinase A inhibits tumor mutator APOBEC3B through phosphorylation. Scientific reports, 2019, 06-05, Volume: 9, Issue:1 Topics: Catalytic Domain; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cytidine Deaminase; Cytoplasm; Cytosine; DNA, Single-Stranded; Fluorescence Resonance Energy Transfer; HEK293 Cells; HeLa Cells; Humans; Minor Histocompatibility Antigens; Molecular Dynamics Simulation; Mutation; Neoplasms; Phosphorylation; Threonine	2019
A novel pan-cancer biomarker plasma heat shock protein 90alpha and its diagnosis determinants in clinic. Cancer science, 2019, Volume: 110, Issue:9 Topics: ADAM10 Protein; Adolescent; Adult; Amyloid Precursor Protein Secretases; Animals; Biomarkers, Tumor; Cell Line, Tumor; Child; Child, Preschool; Datasets as Topic; Enzyme-Linked Immunosorbent Assay; Exosomes; False Negative Reactions; Female; HSP90 Heat-Shock Proteins; Humans; Infant; Infant, Newborn; Male; Membrane Proteins; Mice; Middle Aged; Neoplasms; Phosphorylation; Prospective Studies; ROC Curve; Threonine; Xenograft Model Antitumor Assays; Young Adult	2019
Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells. The Journal of biological chemistry, 2013, Dec-06, Volume: 288, Issue:49 Topics: Cell Line, Tumor; Glycolysis; HEK293 Cells; Hep G2 Cells; Humans; Neoplasms; Oncogenes; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyruvate Kinase; Recombinant Fusion Proteins; Threonine; Two-Hybrid System Techniques; Virus Integration	2013
Methionine to isothreonine conversion as a source of false discovery identifications of genetically encoded variants in proteogenomics. Journal of proteomics, 2015, Apr-29, Volume: 120 Topics: Amino Acid Substitution; Artifacts; Cell Line, Tumor; False Positive Reactions; Genetic Markers; Genetic Variation; Humans; Methionine; Neoplasms; Proteome; Proteomics; Reproducibility of Results; Sensitivity and Specificity; Threonine	2015
PKCδ stabilizes TAp63 to promote cell apoptosis. FEBS letters, 2015, Jul-22, Volume: 589, Issue:16 Topics: Amino Acid Substitution; Apoptosis; Gene Expression Regulation, Neoplastic; Humans; Mutagenesis, Site-Directed; Mutant Proteins; Neoplasms; Phosphorylation; Protein Interaction Domains and Motifs; Protein Isoforms; Protein Kinase C; Protein Processing, Post-Translational; Protein Stability; Proto-Oncogene Proteins c-myc; Recombinant Fusion Proteins; Recombinant Proteins; Threonine; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins	2015
Threonine 209 phosphorylation on RUNX3 by Pak1 is a molecular switch for its dualistic functions. Oncogene, 2016, 09-15, Volume: 35, Issue:37 Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Nucleus; Core Binding Factor Alpha 3 Subunit; Cytoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mutagenesis, Site-Directed; Neoplasms; Phosphorylation; Threonine; Xenograft Model Antitumor Assays	2016
14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression. Scientific reports, 2016, 06-02, Volume: 6 Topics: 14-3-3 Proteins; Aneuploidy; Animals; cdc25 Phosphatases; Cell Cycle; Cell Line, Tumor; Centrosome; Chromosomal Instability; Gene Deletion; HCT116 Cells; Humans; Mice; Neoplasm Transplantation; Neoplasms; Nuclear Proteins; Nucleophosmin; Phosphorylation; Threonine	2016
Is chondroitin sulfate responsible for the biological effects attributed to the GC protein-derived Macrophage Activating Factor (GcMAF)? Medical hypotheses, 2016, Volume: 94 Topics: Animals; Antineoplastic Agents; Cell Membrane; Cell Proliferation; Cholecalciferol; Chondroitin Sulfates; Glycosylation; Humans; Immunosuppression Therapy; Immunotherapy; Macrophage-Activating Factors; Macrophages; Models, Theoretical; Neoplasms; Neovascularization, Pathologic; Oleic Acid; Peptides; Signal Transduction; Threonine; Vitamin D-Binding Protein	2016
SCF(Fbxw7/hCdc4) targets cyclin E2 for ubiquitin-dependent proteolysis. Experimental cell research, 2009, Jul-01, Volume: 315, Issue:11 Topics: Binding Sites; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cyclin E; Cyclins; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; HeLa Cells; Humans; Mutagenesis, Site-Directed; Neoplasms; Oncogene Proteins; Phosphorylation; Recombinant Proteins; RNA Interference; Serine; Substrate Specificity; Threonine; Ubiquitin; Ubiquitin-Protein Ligases	2009
Cdk1-cyclin B1-mediated phosphorylation of tumor-associated microtubule-associated protein/cytoskeleton-associated protein 2 in mitosis. The Journal of biological chemistry, 2009, Jun-12, Volume: 284, Issue:24 Topics: CDC2 Protein Kinase; Cyclin B; Cyclin B1; Cytoskeletal Proteins; Cytoskeleton; HeLa Cells; Humans; Kidney; Mitosis; Mutagenesis; Neoplasms; Phosphorylation; Protein Structure, Tertiary; RNA, Small Interfering; Spindle Apparatus; Threonine	2009
LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain. The Journal of biological chemistry, 2010, Jun-11, Volume: 285, Issue:24 Topics: AMP-Activated Protein Kinase Kinases; Animals; Cell Line; Cell Line, Tumor; Cell Movement; Female; Humans; Male; Mice; Mice, Knockout; Neoplasms; p21-Activated Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Threonine	2010
Development and validation of a high-performance liquid chromatography-tandem mass spectrometry method for the determination of the novel proteasome inhibitor CEP-18770 in human plasma and its application in a clinical pharmacokinetic study. Journal of mass spectrometry : JMS, 2010, Volume: 45, Issue:11 Topics: Acetonitriles; Biphenyl Compounds; Boronic Acids; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Drug Stability; Humans; Irbesartan; Multiple Myeloma; Neoplasms; Proteasome Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tetrazoles; Threonine	2010
Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity. Oncotarget, 2011, Volume: 2, Issue:5 Topics: Casein Kinase II; Clinical Trials as Topic; Drug Design; Drug Resistance; Fungal Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Molecular Chaperones; Molecular Targeted Therapy; Neoplasms; Phosphorylation; Resorcinols; Threonine; Yeasts	2011
Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors. Cancer research, 2011, Dec-15, Volume: 71, Issue:24 Topics: Antigens, Neoplasm; Bicarbonates; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Cell Hypoxia; Cell Line; Cell Movement; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Space; HEK293 Cells; HeLa Cells; HT29 Cells; Humans; Hydrogen-Ion Concentration; Immunoblotting; Mutation; Neoplasms; Phosphorylation; Protein Binding; Serine; Sodium-Bicarbonate Symporters; Threonine	2011
Development and application of an in vitro apoptin kinase assay. Analytical biochemistry, 2012, Feb-01, Volume: 421, Issue:1 Topics: Active Transport, Cell Nucleus; Adenosine Triphosphate; Amino Acid Sequence; Apoptosis; Capsid Proteins; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase 2; Cytoplasm; HeLa Cells; Humans; In Vitro Techniques; Jurkat Cells; Kinetics; Mass Spectrometry; Neoplasms; Phosphorylation; Protein Kinase C; Protein Kinases; Recombinant Fusion Proteins; Threonine	2012
The threonine protease activity of testes-specific protease 50 (TSP50) is essential for its function in cell proliferation. PloS one, 2012, Volume: 7, Issue:5 Topics: Alleles; Animals; Apoptosis; Catalytic Domain; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Doxorubicin; Drug Resistance, Neoplasm; HEK293 Cells; Humans; I-kappa B Kinase; Mice; Models, Molecular; Neoplasms; NF-kappa B; Point Mutation; Serine Endopeptidases; Signal Transduction; Threonine	2012
A single mutation in Securin induces chromosomal instability and enhances cell invasion. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2 Topics: Animals; Cell Transformation, Neoplastic; Chlorocebus aethiops; Chromosomal Instability; COS Cells; Gene Expression; HCT116 Cells; HeLa Cells; Humans; Microarray Analysis; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms; Point Mutation; Securin; Threonine; Transfection	2013
Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. PloS one, 2012, Volume: 7, Issue:9 Topics: Acyclovir; Adenosine; Bacillus subtilis; Catalysis; Catalytic Domain; Crystallography, X-Ray; Ganciclovir; Genetic Therapy; Humans; Ligands; Models, Molecular; Molecular Conformation; Neoplasms; Phosphates; Prodrugs; Protein Structure, Quaternary; Purine-Nucleoside Phosphorylase; Serine; Threonine; Tubercidin	2012
Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma. Human pathology, 2013, Volume: 44, Issue:5 Topics: Adenocarcinoma; Amino Acid Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; ets-Domain Protein Elk-1; Humans; Immunohistochemistry; Neoplasms; Phosphorylation; Threonine; Transcriptional Activation	2013
Synthesis and phorbol ester binding of the cysteine-rich domains of diacylglycerol kinase (DGK) isozymes. DGKgamma and DGKbeta are new targets of tumor-promoting phorbol esters. The Journal of biological chemistry, 2003, May-16, Volume: 278, Issue:20 Topics: Amino Acid Sequence; Animals; Binding, Competitive; Chromatography, High Pressure Liquid; Cricetinae; Cysteine; Diacylglycerol Kinase; Gene Deletion; Green Fluorescent Proteins; Humans; Kinetics; Luminescent Proteins; Molecular Sequence Data; Mutation; Neoplasms; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Binding; Protein Conformation; Protein Folding; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Time Factors	2003
Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation. The Journal of biological chemistry, 2003, Aug-08, Volume: 278, Issue:32 Topics: 3T3 Cells; Alleles; Alternative Splicing; Animals; Binding Sites; Cell Cycle; Cell Nucleus; Cell Transformation, Neoplastic; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cytoplasm; DNA; Flow Cytometry; Green Fluorescent Proteins; Humans; Immunoblotting; Luminescent Proteins; Mice; Microscopy, Fluorescence; Models, Genetic; Neoplasms; Phosphorylation; Plasmids; Polymorphism, Genetic; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Mas; Proto-Oncogene Proteins; Retinoblastoma Protein; Threonine; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured	2003
Blocking survivin to kill cancer cells. Methods in molecular biology (Clifton, N.J.), 2003, Volume: 223 Topics: Alanine; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; DNA, Complementary; Genes, Dominant; Genetic Techniques; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Multigene Family; Mutation; Neoplasm Proteins; Neoplasms; Oligonucleotides, Antisense; Plasmids; Point Mutation; Prognosis; Survivin; Threonine	2003
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Nov-04, Volume: 257 Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine	1963
FREE AMINO ACIDS OF HUMAN BREAST CANCER. The Nebraska state medical journal, 1964, Volume: 49 Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine	1964
Formation of acrolein-derived 2'-deoxyadenosine adduct in an iron-induced carcinogenesis model. The Journal of biological chemistry, 2003, Dec-12, Volume: 278, Issue:50 Topics: Acrolein; Aldehydes; Animals; Antibodies, Monoclonal; Binding, Competitive; Cattle; Cell Nucleus; Deoxyadenosines; DNA Adducts; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Ions; Iron; Lipid Peroxidation; Liver; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Chemical; Neoplasms; Oxidative Stress; Oxygen; Peroxidase; Rats; Rats, Wistar; Threonine; Thymus Gland; Time Factors	2003
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nature cell biology, 2004, Volume: 6, Issue:4 Topics: Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Cell Line; Cell Transformation, Neoplastic; Genes, myc; Humans; Mice; Mutation; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-myc; Rats; RNA Stability; Serine; Signal Transduction; Threonine	2004
C-terminal sequences direct cyclin D1-CRM1 binding. The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53 Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Cell Proliferation; Cyclin D1; Epitopes; Exportin 1 Protein; Fibroblasts; Humans; Immunoblotting; Karyopherins; Mice; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Neoplasms; NIH 3T3 Cells; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Threonine; Time Factors	2004
CDKN2A common variant and multi-organ cancer risk--a population-based study. International journal of cancer, 2006, Jun-15, Volume: 118, Issue:12 Topics: Adult; Aged; Alanine; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Female; Genes, p16; Genetic Variation; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Odds Ratio; Poland; Prevalence; Risk Assessment; Risk Factors; Threonine	2006
Activating PTPN11 mutations play a minor role in pediatric and adult solid tumors. Cancer genetics and cytogenetics, 2006, Apr-15, Volume: 166, Issue:2 Topics: Adult; Child; Cohort Studies; Enzyme Activation; Exons; Humans; Intracellular Signaling Peptides and Proteins; Models, Molecular; Mutation; Neoplasms; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Threonine	2006
Ubiquitin-independent proteasomal degradation of Fra-1 is antagonized by Erk1/2 pathway-mediated phosphorylation of a unique C-terminal destabilizer. Molecular and cellular biology, 2007, Volume: 27, Issue:11 Topics: Amino Acid Sequence; Animals; Cell Cycle; Cell Line; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fos; Sequence Alignment; Serine; Threonine; Ubiquitin	2007
The extracolonic cancer spectrum in females with the common 'South African' hMLH1 c.C1528T mutation. Familial cancer, 2008, Volume: 7, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Adult; Alleles; Case-Control Studies; Cohort Studies; Colorectal Neoplasms, Hereditary Nonpolyposis; Cysteine; Female; Genetic Predisposition to Disease; Humans; Incidence; Microsatellite Instability; Middle Aged; Mutation; MutL Protein Homolog 1; Neoplasms; Neoplasms, Multiple Primary; Nuclear Proteins; Phenotype; Population Surveillance; Risk Factors; Sex Factors; Siblings; South Africa; Threonine	2008
CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib. Blood, 2008, Mar-01, Volume: 111, Issue:5 Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Inhibitors; Humans; Macrophage Colony-Stimulating Factor; Mice; Mice, Nude; Multiple Myeloma; Neoplasms; NF-kappa B; Osteogenesis; Proteasome Inhibitors; Pyrazines; RANK Ligand; Threonine; Treatment Outcome; Ubiquitin; Xenograft Model Antitumor Assays	2008
Phorbol ester-induced threonine phosphorylation of the human epidermal growth factor receptor occurs within the EGF binding domain. Biochemical and biophysical research communications, 1984, Sep-17, Volume: 123, Issue:2 Topics: Binding Sites; Cell Line; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; Humans; Models, Biological; Neoplasms; Peptide Fragments; Phorbols; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine; Trypsin	1984
Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain. Biochimica et biophysica acta, 1994, Aug-02, Volume: 1218, Issue:3 Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Colon; Colonic Neoplasms; DNA Primers; DNA, Complementary; Gene Expression; Humans; Liver; Molecular Sequence Data; Neoplasms; Phosphorylation; Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger; RNA, Neoplasm; Sequence Homology, Amino Acid; Serine; Threonine; Zinc Fingers	1994
Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. Molecular and cellular biology, 2001, Volume: 21, Issue:8 Topics: Animals; Base Sequence; Binding Sites; Cell Division; Cell Line; DNA Primers; Drug Stability; Dual-Specificity Phosphatases; Genes, p53; Humans; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mass Spectrometry; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinase Phosphatases; Mitogen-Activated Protein Kinases; Mutation; Neoplasms; Oligonucleotides, Antisense; Phosphorylation; Protein Tyrosine Phosphatases; Stress, Physiological; Threonine; Transcription, Genetic; Tumor Suppressor Protein p53; Ultraviolet Rays	2001
O-phospho-L-tyrosine protects TP53 wild-type cells against ionizing radiation. International journal of cancer, 2001, Volume: 96 Suppl Topics: Blotting, Western; Cell Line, Transformed; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Complementary; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Mutation; Neoplasms; Phosphotyrosine; Radiation-Protective Agents; Serine; Threonine; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2001
Isolation and identification of urinary beta-aspartyl dipeptides and their concentrations in human urine. Journal of biochemistry, 1978, Volume: 84, Issue:3 Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Child; Dipeptides; Female; Glutamates; Glycine; Humans; Hydrogen-Ion Concentration; Male; Methionine; Middle Aged; Neoplasms; Parenteral Nutrition, Total; Sex Factors; Threonine; Uremia	1978
[The c-raf oncogene]. Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:8 Topics: Amino Acid Sequence; Animals; DNA, Neoplasm; Humans; Molecular Sequence Data; Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogenes; Serine; Signal Transduction; Threonine; Transfection	1990
The erythrocyte plasma distribution of amino acids in health and disease. Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 20, Issue:1 Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine	1968