threonine and Amyotrophic Lateral Sclerosis

threonine has been researched along with Amyotrophic Lateral Sclerosis in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (4.55)	18.7374
1990's	8 (36.36)	18.2507
2000's	5 (22.73)	29.6817
2010's	7 (31.82)	24.3611
2020's	1 (4.55)	2.80

Authors

Authors	Studies
Başak, AN; Diker, S; Ergoren, MC; Gelener, P; Tan, E; Teralı, K; Tunca, C	1
Bougea, A; Bourbouli, M; Constantinides, VC; Evdokimidis, I; Kapaki, E; Paraskevas, GP; Rentzos, M; Zaganas, I; Zouvelou, V	1
Brown, A; McKee, A; Moszczynski, AJ; Strong, MJ; Strong, W; Xu, K	1
Gohar, M; Leystra-Lantz, C; Moszczynski, AJ; Strong, MJ; Strong, W; Volkening, K	1
Andersen, PM; Böhm, S; Borck, G; Brenner, D; Danzer, KM; Hübers, A; Kassubek, J; Ludolph, AC; Lulé, D; Meitinger, T; Müller, K; Neuwirth, C; Otto, M; Strom, TM; Volk, AE; Wahlqvist, M; Weber, M; Weishaupt, JH; Weydt, P; Wieland, T	1
Gohar, M; Leystra-Lantz, C; Strong, MJ; Strong, W; Volkening, K; Yang, W	1
Borghero, G; Brunetti, M; Calvo, A; Chiò, A; Cistaro, A; Marrosu, MG; Moglia, C; Montuschi, A; Murru, MR; Mutani, R; Ossola, I; Restagno, G; Schymick, JC; Ticca, A; Traynor, BJ	1
Ammassari-Teule, M; Bernardi, G; Berretta, N; Domenici, L; Longone, P; Nutini, M; Origlia, N; Sgobio, C; Spalloni, A; Trabalza, A	1
Abramzon, Y; Arepalli, S; Borghero, G; Brunetti, M; Calvo, A; Cannas, A; Chiò, A; Chong, S; Cossu, P; Floris, G; Hernandez, DG; Johnson, JO; Marrosu, MG; Moglia, C; Murru, MR; Mutani, R; Nalls, MA; Ossola, I; Parish, LD; Pugliatti, M; Restagno, G; Ticca, A; Traynor, BJ	1
Leigh, PN; Mitsumoto, H; Parton, M	2
Hays, AP; He, CZ; Mitsumoto, H; Naini, A; Rowland, LP	1
Chan, KH; Cheng, TS; Cheung, RT; Chu, AC; Fong, GC; Ho, PW; Ho, SL; Kung, MH; Kwok, KH; Mak, W; Ramsden, DB; Song, YQ	1
Brock, DJ; Chancellor, AM; Jones, CT; Swingler, RJ; Warlow, CP	1
Hugon, J	1
Arciero, K; Badger, GJ; Betts, EF; Bromberg, MB; Carpenter, J; Forshew, D; Fries, TJ; Krusinski, PB; Nau, K; Tandan, R	1
Moriwaka, F	1
Aubrespy, G; Blin, O; Crevat, A; Guelton, C; Pouget, J; Serratrice, G	2
Caraceni, T; Fetoni, V; Girotti, F; Testa, D	1
Ardissonne, JP; Aubrespy, G; Blin, O; Crevat, A; Desnuelle, C; Guelton, C; Pouget, J; Serratrice, G	1
Roufs, JB	1

Reviews

4 review(s) available for threonine and Amyotrophic Lateral Sclerosis

Article	Year
Amino acids for amyotrophic lateral sclerosis / motor neuron disease. The Cochrane database of systematic reviews, 2003, Issue:4 Topics: Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Humans; Motor Neuron Disease; Randomized Controlled Trials as Topic; Threonine	2003
WITHDRAWN: Amino acids for amyotrophic lateral sclerosis / motor neuron disease. The Cochrane database of systematic reviews, 2008, Apr-16, Issue:2 Topics: Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Humans; Motor Neuron Disease; Randomized Controlled Trials as Topic; Threonine	2008
Excitotoxic blocking strategies in amyotrophic lateral sclerosis. Advances in neurology, 1995, Volume: 68 Topics: Amyotrophic Lateral Sclerosis; Anticonvulsants; Humans; Lamotrigine; Neurotoxins; Presynaptic Terminals; Receptors, N-Methyl-D-Aspartate; Threonine; Triazines	1995
[Amyotrophic lateral sclerosis]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1997, Volume: 72, Issue:1 Topics: Adult; Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Animals; Autoimmunity; Double-Blind Method; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Nerve Growth Factors; Nerve Tissue Proteins; Point Mutation; Randomized Controlled Trials as Topic; Riluzole; Superoxide Dismutase; Thiazoles; Threonine	1997

Trials

5 trial(s) available for threonine and Amyotrophic Lateral Sclerosis

Article	Year
A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology, 1996, Volume: 47, Issue:5 Topics: Adult; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Analysis of Variance; Double-Blind Method; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Threonine; Valine	1996
A double-blind placebo-controlled trial of L-threonine in amyotrophic lateral sclerosis. Journal of neurology, 1992, Volume: 239, Issue:2 Topics: Aged; Amyotrophic Lateral Sclerosis; Double-Blind Method; Female; Humans; Male; Middle Aged; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Severity of Illness Index; Threonine	1992
Chronic treatment with L-threonine in amyotrophic lateral sclerosis: a pilot study. Clinical neurology and neurosurgery, 1992, Volume: 94, Issue:1 Topics: Administration, Oral; Adult; Aged; Amyotrophic Lateral Sclerosis; Drug Administration Schedule; Female; Follow-Up Studies; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neurologic Examination; Receptors, N-Methyl-D-Aspartate; Threonine	1992
[Anomaly in the neurotransmitter amino acids in amyotrophic lateral sclerosis: a therapeutic application]. Revue neurologique, 1991, Volume: 147, Issue:5 Topics: Adult; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Double-Blind Method; Female; Glutamates; Humans; Male; Middle Aged; Neurotransmitter Agents; Threonine	1991
[Short-term double-blind vs placebo trial of L-threonine in amyotrophic lateral sclerosis]. Presse medicale (Paris, France : 1983), 1989, Sep-30, Volume: 18, Issue:30 Topics: Aged; Amyotrophic Lateral Sclerosis; Double-Blind Method; Humans; Middle Aged; Placebos; Randomized Controlled Trials as Topic; Threonine; Time Factors	1989

Other Studies

13 other study(ies) available for threonine and Amyotrophic Lateral Sclerosis

Article	Year
A combined clinical and computational approach to understand the SOD1 Acta neurologica Belgica, 2022, Volume: 122, Issue:4 Topics: Amyotrophic Lateral Sclerosis; Female; Humans; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Threonine	2022
Cerebrospinal Fluid TAR DNA-Binding Protein 43 Combined with Tau Proteins as a Candidate Biomarker for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Spectrum Disorders. Dementia and geriatric cognitive disorders, 2017, Volume: 44, Issue:3-4 Topics: Aged; Amyloid beta-Peptides; Amyotrophic Lateral Sclerosis; Biomarkers; DNA-Binding Proteins; Female; Frontotemporal Dementia; Humans; Male; Middle Aged; Peptide Fragments; Phosphorylation; Pick Disease of the Brain; tau Proteins; Threonine	2017
Pathologic Thr Neurology, 2018, 01-30, Volume: 90, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Animals; Chronic Traumatic Encephalopathy; Disease Models, Animal; Female; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Spinal Cord; tau Proteins; Threonine	2018
Thr175-phosphorylated tau induces pathologic fibril formation via GSK3β-mediated phosphorylation of Thr231 in vitro. Neurobiology of aging, 2015, Volume: 36, Issue:3 Topics: Amino Acid Motifs; Amyotrophic Lateral Sclerosis; Cell Death; Cells, Cultured; Computational Biology; Gene Knockdown Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Neurofibrils; Phosphorylation; RNA, Small Interfering; tau Proteins; Tauopathies; Threonine	2015
NEK1 mutations in familial amyotrophic lateral sclerosis. Brain : a journal of neurology, 2016, Volume: 139, Issue:Pt 5 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Brain; Cohort Studies; Family Health; Female; Gene Frequency; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; NIMA-Related Kinase 1; Respiratory Insufficiency; Serine; Threonine	2016
Tau phosphorylation at threonine-175 leads to fibril formation and enhanced cell death: implications for amyotrophic lateral sclerosis with cognitive impairment. Journal of neurochemistry, 2009, Volume: 108, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Blotting, Western; Caspases; Cell Death; Cell Line; Cognition Disorders; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoprecipitation; Microscopy, Confocal; Neurofibrils; Phosphorylation; Plasmids; Solubility; tau Proteins; Threonine; Transfection; Tubulin	2009
Amyotrophic lateral sclerosis-frontotemporal lobar dementia in 3 families with p.Ala382Thr TARDBP mutations. Archives of neurology, 2010, Volume: 67, Issue:8 Topics: Adult; Aged; Alanine; Amyotrophic Lateral Sclerosis; Brain; Cognition Disorders; DNA-Binding Proteins; Family Health; Female; Frontotemporal Lobar Degeneration; Functional Laterality; Humans; Italy; Magnetic Resonance Imaging; Male; Middle Aged; Mutation, Missense; Positron-Emission Tomography; Superoxide Dismutase; Superoxide Dismutase-1; Threonine	2010
Postsynaptic alteration of NR2A subunit and defective autophosphorylation of alphaCaMKII at threonine-286 contribute to abnormal plasticity and morphology of upper motor neurons in presymptomatic SOD1G93A mice, a murine model for amyotrophic lateral scler Cerebral cortex (New York, N.Y. : 1991), 2011, Volume: 21, Issue:4 Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Evoked Potentials; Fluorescent Antibody Technique; Humans; Mice; Mice, Transgenic; Microscopy, Confocal; Motor Neurons; Mutation; Neuronal Plasticity; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxide Dismutase-1; Threonine	2011
Large proportion of amyotrophic lateral sclerosis cases in Sardinia due to a single founder mutation of the TARDBP gene. Archives of neurology, 2011, Volume: 68, Issue:5 Topics: Aged; Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Case-Control Studies; DNA Mutational Analysis; DNA-Binding Proteins; Female; Founder Effect; Genetic Predisposition to Disease; Genotype; Humans; Italy; Male; Middle Aged; Mutation, Missense; Phenotype; Prospective Studies; RNA-Binding Protein FUS; Superoxide Dismutase; Superoxide Dismutase-1; Threonine	2011
Sporadic amyotrophic lateral sclerosis and breast cancer: Hyaline conglomerate inclusions lead to identification of SOD1 mutation. Journal of the neurological sciences, 2006, Mar-15, Volume: 242, Issue:1-2 Topics: Aged; Amyotrophic Lateral Sclerosis; Breast Neoplasms; DNA Mutational Analysis; Female; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Isoleucine; Nerve Degeneration; Superoxide Dismutase; Superoxide Dismutase-1; Threonine	2006
Clinical phenotypes of a large Chinese multigenerational kindred with autosomal dominant familial ALS due to Ile149Thr SOD1 gene mutation. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2006, Volume: 7, Issue:3 Topics: Adult; Amyotrophic Lateral Sclerosis; Asian People; Ciliary Neurotrophic Factor; DNA Mutational Analysis; Exons; Family Health; Female; Humans; Isoleucine; Male; Middle Aged; Pedigree; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Superoxide Dismutase-1; Threonine; Vascular Endothelial Growth Factor A	2006
Cu/Zn superoxide dismutase (SOD1) mutations and sporadic amyotrophic lateral sclerosis. Lancet (London, England), 1993, Oct-23, Volume: 342, Issue:8878 Topics: Amyotrophic Lateral Sclerosis; Exons; Female; Humans; Isoleucine; Male; Mutation; Superoxide Dismutase; Threonine	1993
L-threonine as a symptomatic treatment for amyotrophic lateral sclerosis (ALS). Medical hypotheses, 1991, Volume: 34, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Central Nervous System; Glycine; Humans; Models, Biological; Threonine	1991