Page last updated: 2024-11-05

thiram and Pregnancy

thiram has been researched along with Pregnancy in 23 studies

Thiram: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.
thiram : An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" In fat tissues, the key genes Lep, Nmb and Nmbr were altered in high dosed offspring, and were differentially expressed between sexes."1.48Effects on metabolic parameters in young rats born with low birth weight after exposure to a mixture of pesticides. ( Axelstad, M; Christiansen, S; Hass, U; Mandrup, K; Ramhøj, L; Svingen, T; Vinggaard, AM, 2018)
"Thiram is a widely used dithiocarbamate fungicide."1.30Assessment of mutagenic potential of thiram. ( Agrawal, RC; Mehrotra, NK; Shukla, Y, 1997)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199017 (73.91)18.7374
1990's3 (13.04)18.2507
2000's2 (8.70)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Svingen, T1
Ramhøj, L1
Mandrup, K1
Christiansen, S1
Axelstad, M1
Vinggaard, AM1
Hass, U1
Stoker, TE1
Jeffay, SC1
Zucker, RM1
Cooper, RL1
Perreault, SD1
Domshlak, MG1
Jasim, S1
Tjälve, H1
Danielsson, BR3
Oskarsson, A1
Dencker, L2
Aleksandrov, SE1
Agrawal, RC1
Shukla, Y1
Mehrotra, NK1
Trifonova, TK1
Antsiferov, SD1
Zhavoronkov, NI1
Vasilos, AF1
Anisimova, LA1
Todorova, EA1
Dmitrienko, VD1
Short, RD1
Russel, JQ1
Minor, JL1
Lee, CC1
Khayat, A1
Sal'nikova, LS1
Badaeva, LN1
Kokshareva, NV1
Ovsiannikova, LM1
Perekhrestenko, VA1
Kiseleva, NI1
Hornshaw, TC1
Aulerich, RJ1
Ringer, RK1
Matthiaschk, G1
Davydova, TB1
Ghizelea, G1
Ozeranschi, L1
Shumskaia, NI1
Stasenkova, KP1
Roll, R1
Robens, JF1

Reviews

1 review available for thiram and Pregnancy

ArticleYear
Thiram.
    IARC monographs on the evaluation of carcinogenic risks to humans, 1991, Volume: 53

    Topics: Air Pollutants, Occupational; Animals; Carcinogenicity Tests; Cross-Cultural Comparison; Female; Hum

1991

Other Studies

22 other studies available for thiram and Pregnancy

ArticleYear
Effects on metabolic parameters in young rats born with low birth weight after exposure to a mixture of pesticides.
    Scientific reports, 2018, 01-10, Volume: 8, Issue:1

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Adipose Tissue; Animals; Butyrates; Carbamates; Diabetes Mellit

2018
Abnormal fertilization is responsible for reduced fecundity following thiram-induced ovulatory delay in the rat.
    Biology of reproduction, 2003, Volume: 68, Issue:6

    Topics: Animals; Embryo, Mammalian; Female; Fertility; Fertilization; Fungicides, Industrial; Image Interpre

2003
[Calculating risk and relative genetic effects of some alkylating agents].
    Meditsina truda i promyshlennaia ekologiia, 2003, Issue:9

    Topics: Animals; Aziridines; Cells, Cultured; Chromates; Embryo, Mammalian; Female; Lethal Dose 50; Male; Mi

2003
Effect of thiuram sulphides on the uptake and distribution of nickel in pregnant and non-pregnant mice.
    Toxicology, 1984, Sep-28, Volume: 32, Issue:4

    Topics: Administration, Oral; Animals; Autoradiography; Disulfiram; Ditiocarb; Female; Fetus; Maternal-Fetal

1984
Placental transfer and fetal distribution of cadmium and mercury after treatment with dithiocarbamates.
    Archives of toxicology, 1984, Volume: 55, Issue:3

    Topics: Animals; Autoradiography; Cadmium; Disulfiram; Ditiocarb; Female; Fetus; Maternal-Fetal Exchange; Me

1984
Placental transfer and fetal distribution of lead in mice after treatment with dithiocarbamates.
    Archives of toxicology, 1984, Volume: 55, Issue:1

    Topics: Animals; Disulfiram; Ditiocarb; Female; Fetus; Lead; Maternal-Fetal Exchange; Mice; Mice, Inbred C57

1984
[Effect of vulcanizing accelerants on embryolethality in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 93, Issue:1

    Topics: Animals; Benzothiazoles; Estrus; Female; Fetal Death; Mutagens; Pregnancy; Rats; Thiazoles; Thiocarb

1982
Assessment of mutagenic potential of thiram.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1997, Volume: 35, Issue:5

    Topics: Animals; Bone Marrow; Embryonic Development; Female; Fungicides, Industrial; Male; Mice; Micronucleu

1997
[Dilor and fentiuram and the reproductive function of animals].
    Veterinariia, 1976, Issue:12

    Topics: Animal Feed; Animals; Copper; Dose-Response Relationship, Drug; Drug Combinations; Embryo, Mammalian

1976
[Effect of TMTD on animal reproductive function].
    Veterinariia, 1978, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Pregnancy; Rabbits; Reproducti

1978
[Rat reproductive function in acute and chronic tetramethylthiuram disulfide (TMTD) poisoning].
    Gigiena i sanitariia, 1978, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Embryo Loss; Female; Fetal Death; Male; Pregnancy; Rats;

1978
Developmental toxicity of ferric dimethyldithiocarbamate and bis(dimethylthiocarbamoyl) disulfide in rats and mice.
    Toxicology and applied pharmacology, 1976, Volume: 35, Issue:1

    Topics: Animals; Diet; Dimethyldithiocarbamate; Embryo, Mammalian; Female; Ferric Compounds; Fertility; Lact

1976
Foetal and maternal distribution of inhaled mercury vapour in pregnant mice: influence of selenite and dithiocarbamates.
    Pharmacology & toxicology, 1990, Volume: 67, Issue:3

    Topics: Administration, Inhalation; Animals; Disulfiram; Ditiocarb; Female; Fetus; Maternal-Fetal Exchange;

1990
[Study of the embryotropic effect of tiuram EF].
    Gigiena i sanitariia, 1989, Issue:3

    Topics: Animals; Edema; Female; Fetal Diseases; Hemorrhage; Maternal-Fetal Exchange; Mice; Pregnancy; Thioca

1989
[Structural-metabolic and functional-behavioral indices of the postnatal toxicity of tetramethylthiuram disulfide in an experiment].
    Gigiena i sanitariia, 1986, Issue:6

    Topics: Animals; Animals, Newborn; Behavior, Animal; Cardiovascular System; Electron Spin Resonance Spectros

1986
Toxicity of thiram (tetramethylthiuram disulfide) to mink and European ferrets.
    Bulletin of environmental contamination and toxicology, 1987, Volume: 38, Issue:4

    Topics: Animals; Body Weight; Eating; Female; Ferrets; Litter Size; Male; Mink; Pregnancy; Prenatal Exposure

1987
[Influence of L-cysteine on thiram (TMTD)-induced teratogenesis in NMRI-mice].
    Archiv fur Toxikologie, 1973, Mar-28, Volume: 30, Issue:3

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Administration, Oral; Animals; Anti-Infective

1973
[Effect of tetramethylthiuram disulfide on the estrous cycle and the young-bearing function of animals exposed to its inhalation].
    Gigiena i sanitariia, 1973, Volume: 38, Issue:4

    Topics: Animals; Estrus; Female; Pregnancy; Rats; Reproduction; Respiration; Thiocarbamates; Thiram; Time Fa

1973
[Influence of the carbamic pesticides, zineb and thiuram, on the estrus cycle and reproductive capacity of white rats].
    Studii si cercetari de endocrinologie, 1973, Volume: 24, Issue:6

    Topics: Animals; Carbamates; Estrus; Female; Fertility; Fungicides, Industrial; Gonadotropins, Pituitary; Me

1973
[Hygienic studies of resins intended for contact with food products].
    Gigiena i sanitariia, 1973, Volume: 38, Issue:8

    Topics: Animals; Female; Food Handling; Male; Pregnancy; Rats; Resins, Plant; Rubber; Thiocarbamates; Thiram

1973
[Teratologic studies with Thiram (TMTD) on two strains of mice].
    Archiv fur Toxikologie, 1971, Volume: 27, Issue:3

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Anti-Infective Agents, Local; Bone Devel

1971
Teratologic studies of carbaryl, diazinon, norea, disulfiram, and thiram in small laboratory animals.
    Toxicology and applied pharmacology, 1969, Volume: 15

    Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents, Local; Bone and Bones; Carbamates; Cric

1969