thiram has been researched along with Poultry Diseases in 45 studies
Thiram: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.
thiram : An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment.
Poultry Diseases: Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiram (50 mg/kg) was added to the diet during 11-14 days to induce TD." | 3.30 | Effects of cold stress on growth performance, carcass traits and tibia attributes in broiler chickens with thiram-induced dyschondroplasia. ( Hassanabadi, A; Saeedi, S; Zaeemi, M, 2023) |
| "Tibial dyschondroplasia (TD) is an intractable avian cartilage disease in which proximal growth plates of tibia lack blood vessels and contain nonviable cells, and it leads to the inflammatory response." | 3.01 | Glutathione-S-transferase A3 protein suppresses thiram-induced tibial dyschondroplasia by regulating prostaglandin-related genes expression. ( Jahejo, AR; Jia, YF; Li, X; Li, Z; Ning, GB; Niu, S; Tian, WX; Tian, ZX; Yang, SX; Zhang, D; Zhang, N; Zhang, YY, 2021) |
| "Tibial dyschondroplasia (TD) is a bone defect of broilers and other poultry birds that disturbs growth plate and it causes lameness." | 2.87 | Clinical efficiency and safety of Hsp90 inhibitor Novobiocin in avian tibial dyschondroplasia. ( Ahmed, N; Arain, MA; Chachar, B; Han, Z; Huang, S; Iqbal, MK; Li, J; Mehmood, K; Nabi, F; Rehman, MU; Shahzad, M; Zhang, H, 2018) |
| " A review of the literature has shown that thiram can affect different organs in animals and its toxic mechanisms can be elucidated in more detail at molecular level." | 2.82 | Thiram exposure in environment: A critical review on cytotoxicity. ( Iqbal, M; Li, Y; Liu, K; Tang, Z; Zhang, H, 2022) |
| "Tibial dyschondroplasia (TD) is a bone disorder in which dead chondrocytes accumulate as a result of apoptosis and non-vascularization in the tibial bone of broiler chickens." | 1.72 | Transcriptome-based biomarker gene screening and evaluation of the extracellular fatty acid-binding protein (Ex-FABP) on immune and angiogenesis-related genes in chicken erythrocytes of tibial dyschondroplasia. ( Bukhari, SAR; Jahejo, AR; Kalhoro, NH; Leghari, IH; Li, Z; Liu, WZ; Rajput, N; Raza, SHA; Tian, WX, 2022) |
| "Manganese (Mn) is an essential microelement for broiler breeding and its deficiency causes tibial dyschondroplasia (TD)." | 1.72 | HIF-1α upregulation exerts the antagonistic effect against angiogenesis inhibition in manganese deficiency-induced tibial dyschondroplasia of broiler chicks. ( Dong, PF; Jin, C; Lu, L; Wang, ZY, 2022) |
| "Thiram is a dithiocarbamate pesticide widely used in agriculture as a fungicide for storing grains to prevent fungal diseases." | 1.72 | Sodium butyrate ameliorates thiram-induced tibial dyschondroplasia and gut microbial dysbiosis in broiler chickens. ( Ding, Y; Fu, Y; Gong, S; He, Y; Iqbal, M; Kulyar, MF; Li, F; Li, J; Mo, Q; Quan, C; Xiao, Y; Yao, W; Zhang, Y, 2022) |
| "Tibial dyschondroplasia (TD) is a leg disorder caused by the abnormal development of the tibia in fast-growing poultry." | 1.62 | Lactobacillus rhamnosus JYLR-005 Prevents Thiram-Induced Tibial Dyschondroplasia by Enhancing Bone-Related Growth Performance in Chickens. ( Cao, QQ; Fu, P; Huang, SC; Kong, A; Liu, DY; Liu, F; Rehman, MU; Tao, KS; Tong, ZX; Wang, XB, 2021) |
| "Pathogenicity of tibial dyschondroplasia (TD) in broiler chickens is not detected yet." | 1.62 | Janus kinase/signal transducer and activator of transcription signaling pathway-related genes STAT3, SOCS3 and their role in thiram induced tibial dyschondroplasia chickens. ( Ahmed, S; Chen, SM; Jahejo, AR; Nabi, F; Ning, GB; Raza, SHA; Tian, WX; Yu, J; Zhang, CL; Zhang, D; Zhao, JF, 2021) |
| "Thiram is a sort of chemical used for pesticide and fungicide." | 1.62 | Chlorogenic acid inhibits apoptosis in thiram-induced tibial dyschondroplasia via intrinsic pathway. ( Guo, K; Kulyar, MF; Li, J; Liu, J; Luo, B; Waqas, M; Zhang, J, 2021) |
| "Thiram is a widely known tibial dyschondroplasia (TD) inducer." | 1.56 | Identification and expression analysis of microRNAs in tibial growth plate of chicken through thiram toxicity. ( Iqbal, M; Li, A; Li, J; Li, Z; Lian, Y; Mehmood, K; Wang, Y; Zhang, H; Zhang, J, 2020) |
| "The Tibial dyschondroplasia (TD) in fast-growing chickens is mainly caused by improper blood circulation." | 1.56 | Transcriptome-based screening of intracellular pathways and angiogenesis related genes at different stages of thiram induced tibial lesions in broiler chickens. ( Chen, HC; Jahejo, AR; Khan, A; Mangi, RA; Niu, S; Qadir, MF; Tian, WX; Zhang, D, 2020) |
| "Tibial dyschondroplasia (TD) is a skeletal deformity disease in broilers that occurs when vascularization in the growth plate (GP) is below normal." | 1.56 | Recombinant glutathione-S-transferase A3 protein regulates the angiogenesis-related genes of erythrocytes in thiram induced tibial lesions. ( Ahsan, A; Jahejo, AR; Kalhoro, DH; Kashif, J; Khan, A; Mangi, RA; Niu, S; Qadir, MF; Qiao, ML; Rajput, N; Tian, WX; Zhang, D, 2020) |
| "Tibial Dyschondroplasia (TD), a metabolic disease of fast growing poultry birds that effects the growth of bone and cartilage, is characterized by anorexia, mental depression and lameness." | 1.51 | Recovery of chicken growth plate by TanshinoneⅡA through wnt/β-catenin pathway in thiram-induced Tibial Dyschondroplasia. ( Shen, Y; Tong, X; Yang, H; Zhang, H; Zhang, J, 2019) |
| "Tibial dyschondroplasia (TD) is a type of bone deformity found in fast-growing chickens, which induce inflammatory responses." | 1.51 | The expression of prostaglandins-related genes in erythrocytes of broiler chicken responds to thiram-induced tibial dyschondroplasia and recombinant glutathione-S-transferase A3 protein. ( Chen, HC; Gao, RK; Gao, SM; Gao, WW; Hao, WF; Huo, NR; Jahejo, AR; Jia, FJ; Li, GL; Li, JH; Li, X; Ma, HL; Ning, GB; Niu, S; Tian, WX; Wang, CX; Yan, F; Zhang, D; Zhao, YJ, 2019) |
| "Tibial dyschondroplasia (TD) is most the common tibiotarsal bone disease in rapidly growing birds throughout the world." | 1.51 | Protective effect of Astragaloside IV to inhibit thiram-induced tibial dyschondroplasia. ( Jiang, X; Lei, L; Li, A; Li, J; Mehmood, K; Qamar, H; Wang, Y; Waqas, M; Yao, W; Zhang, H; Zhang, L, 2019) |
| "Tibial dyschondroplasia (TD) cases has not been reported in Tibetan chickens (TBCs), but it is commonly seen in commercial broilers characterized by lameness." | 1.48 | Tibial dyschondroplasia is closely related to suppression of expression of hypoxia-inducible factors 1α, 2α, and 3α in chickens. ( Huang, S; Iqbal, MK; Li, J; Luo, H; Mehmood, K; Qiu, G; Rehman, MU; Zhang, H, 2018) |
| "Tibial dyschondroplasia (TD) is a disease of rapid growing chickens that occurs in many avian species; it is characterized by nonvascular and nonmineralized growth plates, along with tibia bone deformation and lameness." | 1.48 | Effect of Icariin on Tibial Dyschondroplasia Incidence and Tibial Characteristics by Regulating P2RX7 in Chickens. ( Iqbal, M; Jiang, X; Li, J; Li, K; Mehmood, K; Nabi, F; Rehman, MU; Tong, X; Wang, L; Wang, M; Yao, W; Zhang, H; Zhang, L, 2018) |
| "Thiram treatment significantly reduced the performance of chickens, liver index, and tibial length compared with control group." | 1.48 | Effect of tetramethyl thiuram disulfide (thiram) in relation to tibial dyschondroplasia in chickens. ( Iqbal, M; Jiang, X; Li, A; Li, J; Mehmood, K; Rehman, MU; Shen, Y; Waqas, M; Yao, W; Zhang, H, 2018) |
| "Tibial dyschondroplasia (TD) is an intractable poultry problem that is characterized by the appearance of non-vascularized and non-mineralized cartilage masses in tibial growth plates (TGPs)." | 1.46 | Tibial dyschondroplasia is highly associated with suppression of tibial angiogenesis through regulating the HIF-1α/VEGF/VEGFR signaling pathway in chickens. ( Huang, SC; Iqbal, MK; Lan, YF; Li, JK; Luo, HQ; Mehmood, K; Qiu, G; Rehman, MU; Zhang, H; Zhang, LH, 2017) |
| "Tibial dyschondroplasia (TD) is an important long bone defect of broiler chickens that disturbs the proximal growth plate and is characterized by non-vascularized cartilage, a distended growth plate and lameness." | 1.43 | Hsp90 inhibitor celastrol reinstates growth plate angiogenesis in thiram-induced tibial dyschondroplasia. ( Han, Z; Iqbal, MK; Li, J; Li, K; Liu, J; Nabi, F; Shahzad, M; Zhang, D, 2016) |
| "Tibial dyschondroplasia (TD) is an important tibiotarsal bone disorder characterized by an avascular and nonmineralized growth plate; it is attributed to abnormal differentiation of chondrocytes and causes lameness." | 1.43 | Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia. ( Iqbal, MK; Li, J; Liu, J; Nabi, F; Rehman, MU; Tahir, AH; Zhang, H, 2016) |
| "Tibial dyschondroplasia (TD) is an avian bone disorder of different aetiologies that may be associated with lameness." | 1.42 | Differential expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in avian tibial dyschondroplasia. ( Gao, J; Li, J; Li, K; Liu, J; Nabi, F; Shahzad, M; Wang, Z; Zhang, D, 2015) |
| "Tibial dyschondroplasia (TD) is a common skeletal disorder in broiler chickens." | 1.39 | Screening of differentially expressed genes in the growth plate of broiler chickens with tibial dyschondroplasia by microarray analysis. ( Bi, DR; Guo, DZ; Li, HQ; Li, JK; Ning, GB; Pan, SY; Qiao, JG; Qin, P; Tian, WX; Wang, R, 2013) |
| "In thiram-treated broilers at 15 d old, the chVEGF proteins upregulated the expression of MMP-13 and Runx2, and had different effects on type X collagen and Bcl-2 expression at different dosages." | 1.39 | Expression and identification of recombinant chicken vascular endothelial growth factor in Pichia pastoris and its role in the pathogenesis of tibial dyschondroplasia. ( Deng, YF; Hou, JF; Zhang, JP; Zhou, ZL, 2013) |
| "Thiram is a dithiocarbamate pesticide that causes tibial dyschondroplasia (TD), a growth plate defect, in poultry." | 1.39 | Effect of thiram on avian growth plate chondrocytes in culture. ( Lay, JO; Liyanage, R; Rasaputra, KS; Rath, NC; Slavik, MF, 2013) |
| "Tibial dyschondroplasia (TD) is a skeletal abnormality that can cause economic losses and animal welfare concerns." | 1.38 | The effect of inhibition of heat-shock proteins on thiram-induced tibial dyschondroplasia. ( Genin, O; Hasdai, A; Pines, M; Shinder, D, 2012) |
| "Tibial dyschondroplasia (TD) is characterized by expansion of the proximal growth plates of the tibiotarsus that fail to form bone, lack blood vessels, and contain non-viable cells." | 1.35 | Identification of differentially expressed genes in the growth plate of broiler chickens with thiram-induced tibial dyschondroplasia. ( Bi, DR; Guo, DZ; Li, JK; Pan, SY; Qin, P; Tian, WX; Zhang, WP; Zhang, YH, 2009) |
| "Tibial dyschondroplasia (TD) is a prevalent skeletal abnormality associated with rapid growth rate in many avian species." | 1.35 | Expression of matrix metalloproteinases during impairment and recovery of the avian growth plate. ( Dan, H; Hisdai, A; Monsonego Ornan, E; Sela-Donenfeld, D; Simsa-Maziel, S, 2009) |
| "Tibial dyschondroplasia (TD) is a prevalent skeletal abnormality associated with rapid growth rate in many avian species; it causes enormous economic losses and is an animal welfare problem." | 1.34 | Induction of tibial dyschondroplasia in turkeys by tetramethylthiuram disulfide (thiram). ( Dan, H; Hasdai, A; Ornan, EM; Simsa, S, 2007) |
| "Tibial dyschondroplasia (TD) is a metabolic cartilage disease of young poultry in which endochondral bone formation is disrupted leading to the retention of a non-calcified, avascular plug of cartilage in the tibial growth plate." | 1.33 | Changes in the tibial growth plates of chickens with thiram-induced dyschondroplasia. ( Balog, JM; Huff, GR; Huff, WE; Rath, NC; Richards, MP, 2005) |
| "When thiuram was added to the tibial dyschondroplasia-inducing diet, it also caused a decrease in bone ash and in the total and ultrafilterable plasma calcium." | 1.27 | Observations on several factors influencing the incidence of tibial dyschondroplasia in broiler chickens. ( Edwards, HM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.44) | 18.7374 |
| 1990's | 1 (2.22) | 18.2507 |
| 2000's | 6 (13.33) | 29.6817 |
| 2010's | 20 (44.44) | 24.3611 |
| 2020's | 16 (35.56) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, K | 1 |
| Li, Y | 1 |
| Iqbal, M | 9 |
| Tang, Z | 1 |
| Zhang, H | 13 |
| Jahejo, AR | 10 |
| Bukhari, SAR | 1 |
| Rajput, N | 2 |
| Kalhoro, NH | 2 |
| Leghari, IH | 1 |
| Raza, SHA | 3 |
| Li, Z | 6 |
| Liu, WZ | 1 |
| Tian, WX | 12 |
| Saeedi, S | 1 |
| Hassanabadi, A | 1 |
| Zaeemi, M | 1 |
| Lu, L | 1 |
| Jin, C | 1 |
| Dong, PF | 1 |
| Wang, ZY | 1 |
| Zhang, CL | 2 |
| Nabi, F | 8 |
| Shah, QA | 1 |
| Bhutto, ZA | 1 |
| Zhao, JF | 2 |
| Yu, J | 2 |
| Ning, GB | 8 |
| Zhang, D | 11 |
| Chen, SM | 2 |
| Zhang, Y | 2 |
| Ding, Y | 1 |
| Mo, Q | 1 |
| Kulyar, MF | 2 |
| He, Y | 1 |
| Yao, W | 7 |
| Quan, C | 1 |
| Gong, S | 1 |
| Li, F | 1 |
| Fu, Y | 1 |
| Xiao, Y | 1 |
| Li, J | 17 |
| Yang, H | 2 |
| Tong, X | 4 |
| Zhang, J | 6 |
| Shen, Y | 2 |
| Niu, S | 7 |
| Khan, A | 7 |
| Mangi, RA | 3 |
| Qadir, MF | 3 |
| Li, JH | 3 |
| Li, A | 6 |
| Wang, Y | 5 |
| Mehmood, K | 12 |
| Lian, Y | 1 |
| Waqas, M | 8 |
| Qamar, H | 4 |
| Jiang, X | 7 |
| Chen, HC | 3 |
| Kashif, J | 1 |
| Kalhoro, DH | 1 |
| Qiao, ML | 1 |
| Ahsan, A | 2 |
| Liu, F | 1 |
| Kong, A | 1 |
| Fu, P | 1 |
| Cao, QQ | 1 |
| Tao, KS | 1 |
| Liu, DY | 1 |
| Wang, XB | 1 |
| Tong, ZX | 1 |
| Rehman, MU | 9 |
| Huang, SC | 2 |
| Jia, FJ | 3 |
| Shah, MA | 1 |
| Yin, JJ | 1 |
| Li, X | 2 |
| Zhang, N | 2 |
| Yang, SX | 1 |
| Jia, YF | 1 |
| Zhang, YY | 1 |
| Tian, ZX | 1 |
| Ahmed, S | 1 |
| Luo, B | 1 |
| Liu, J | 4 |
| Guo, K | 1 |
| Huang, S | 2 |
| Qiu, G | 2 |
| Luo, H | 2 |
| Iqbal, MK | 7 |
| Lan, YF | 1 |
| Luo, HQ | 1 |
| Zhang, LH | 1 |
| Li, JK | 3 |
| Li, K | 4 |
| Wang, L | 2 |
| Shahzad, M | 4 |
| Wang, M | 1 |
| Zhang, L | 2 |
| Han, Z | 2 |
| Ahmed, N | 1 |
| Chachar, B | 1 |
| Arain, MA | 1 |
| Wang, CX | 2 |
| Li, HQ | 2 |
| Ma, HL | 2 |
| Hao, WF | 2 |
| Gao, WW | 2 |
| Gao, SM | 2 |
| Li, GL | 2 |
| Yan, F | 2 |
| Gao, RK | 2 |
| Zhao, YJ | 2 |
| Huo, NR | 1 |
| Lei, L | 1 |
| Qin, P | 2 |
| Wang, R | 1 |
| Qiao, JG | 1 |
| Bi, DR | 2 |
| Pan, SY | 2 |
| Guo, DZ | 2 |
| Zhang, JP | 1 |
| Deng, YF | 1 |
| Zhou, ZL | 1 |
| Hou, JF | 1 |
| Gao, J | 1 |
| Wang, Z | 1 |
| Tahir, AH | 1 |
| Zhang, WP | 1 |
| Zhang, YH | 1 |
| Dan, H | 2 |
| Simsa-Maziel, S | 1 |
| Hisdai, A | 1 |
| Sela-Donenfeld, D | 1 |
| Monsonego Ornan, E | 1 |
| Genin, O | 1 |
| Hasdai, A | 2 |
| Shinder, D | 1 |
| Pines, M | 1 |
| Rasaputra, KS | 1 |
| Liyanage, R | 1 |
| Lay, JO | 1 |
| Slavik, MF | 1 |
| Rath, NC | 3 |
| Richards, MP | 1 |
| Huff, WE | 2 |
| Huff, GR | 2 |
| Balog, JM | 1 |
| Kannan, L | 1 |
| Pillai, PB | 1 |
| Horst, RL | 1 |
| Emmert, JL | 1 |
| Simsa, S | 1 |
| Ornan, EM | 1 |
| Bi, D | 1 |
| Pan, S | 1 |
| Guitart, R | 1 |
| Mateo, R | 1 |
| Gutierrez, JM | 1 |
| To-Figueras, J | 1 |
| Veltmann, JR | 1 |
| Linton, SS | 1 |
| Edwards, HM | 1 |
1 review available for thiram and Poultry Diseases
| Article | Year |
|---|---|
Thiram exposure in environment: A critical review on cytotoxicity.
Topics: Animals; Chickens; Osteochondrodysplasias; Phosphatidylinositol 3-Kinases; Poultry Diseases; Thiram | 2022 |
5 trials available for thiram and Poultry Diseases
| Article | Year |
|---|---|
Effects of cold stress on growth performance, carcass traits and tibia attributes in broiler chickens with thiram-induced dyschondroplasia.
Topics: Animals; Chickens; Cold-Shock Response; Male; Osteochondrodysplasias; Poultry Diseases; Thiram; Tibi | 2023 |
Glutathione-S-transferase A3 protein suppresses thiram-induced tibial dyschondroplasia by regulating prostaglandin-related genes expression.
Topics: Animals; Chickens; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Male; Osteochon | 2021 |
Clinical efficiency and safety of Hsp90 inhibitor Novobiocin in avian tibial dyschondroplasia.
Topics: Animals; Chickens; Enzyme Inhibitors; Gene Expression Regulation; Growth Plate; HSP90 Heat-Shock Pro | 2018 |
Evaluation of the efficacy of vitamin D3 or its metabolites on thiram-induced tibial dyschondroplasia in chickens.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Bone and Bones; Calci | 2007 |
Effect of diet with thiram on liver antioxidant capacity and tibial dyschondroplasia in broilers.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Chickens; Diet; Glut | 2007 |
39 other studies available for thiram and Poultry Diseases
| Article | Year |
|---|---|
Transcriptome-based biomarker gene screening and evaluation of the extracellular fatty acid-binding protein (Ex-FABP) on immune and angiogenesis-related genes in chicken erythrocytes of tibial dyschondroplasia.
Topics: Animals; Biomarkers; Chickens; Erythrocytes; Fatty Acid-Binding Proteins; Growth Plate; Neovasculari | 2022 |
HIF-1α upregulation exerts the antagonistic effect against angiogenesis inhibition in manganese deficiency-induced tibial dyschondroplasia of broiler chicks.
Topics: Animals; Chickens; Manganese; Osteochondrodysplasias; Poultry Diseases; Thiram; Tibia; Up-Regulation | 2022 |
Screening of Proliferation-Related Genes and Pathological Changes in Thiram-Induced Tibial Dyschondroplasia.
Topics: Animals; Cell Proliferation; Chickens; Growth Plate; Osteochondrodysplasias; Poultry Diseases; Proli | 2022 |
Sodium butyrate ameliorates thiram-induced tibial dyschondroplasia and gut microbial dysbiosis in broiler chickens.
Topics: Animals; beta Catenin; Butyric Acid; Chickens; Core Binding Factor Alpha 1 Subunit; Dysbiosis; Ecosy | 2022 |
Recovery of chicken growth plate by TanshinoneⅡA through wnt/β-catenin pathway in thiram-induced Tibial Dyschondroplasia.
Topics: Abietanes; Animals; beta Catenin; Chickens; Growth Plate; Osteochondrodysplasias; Poultry Diseases; | 2019 |
Transcriptome analysis of MAPK signaling pathway and associated genes to angiogenesis in chicken erythrocytes on response to thiram-induced tibial lesions.
Topics: Animals; Chickens; Erythrocytes; Fungicides, Industrial; Gene Expression Profiling; MAP Kinase Signa | 2019 |
Identification and expression analysis of microRNAs in tibial growth plate of chicken through thiram toxicity.
Topics: Animals; Chickens; Fungicides, Industrial; Growth Plate; MicroRNAs; Osteochondrodysplasias; Poultry | 2020 |
Puerarin enhance vascular proliferation and halt apoptosis in thiram-induced avian tibial dyschondroplasia by regulating HIF-1α, TIMP-3 and BCL-2 expressions.
Topics: Animals; Antioxidants; Apoptosis; Cell Proliferation; Chickens; Fungicides, Industrial; Glutathione | 2020 |
Transcriptome-based screening of intracellular pathways and angiogenesis related genes at different stages of thiram induced tibial lesions in broiler chickens.
Topics: Animals; Chickens; Gene Ontology; Neovascularization, Physiologic; Osteochondrodysplasias; Poultry D | 2020 |
Ameliorative effect of naringin against thiram-induced tibial dyschondroplasia in broiler chicken.
Topics: Animals; Chickens; Flavanones; Osteochondrodysplasias; Poultry Diseases; Thiram; Tibia | 2020 |
Recombinant glutathione-S-transferase A3 protein regulates the angiogenesis-related genes of erythrocytes in thiram induced tibial lesions.
Topics: Animals; Chickens; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Growth Plate; I | 2020 |
Lactobacillus rhamnosus JYLR-005 Prevents Thiram-Induced Tibial Dyschondroplasia by Enhancing Bone-Related Growth Performance in Chickens.
Topics: Animals; Chickens; Lacticaseibacillus rhamnosus; Osteochondrodysplasias; Poultry Diseases; Thiram; T | 2021 |
Screening of toll-like receptor signaling pathway-related genes and the response of recombinant glutathione S-transferase A3 protein to thiram induced apoptosis in chicken erythrocytes.
Topics: Animals; Apoptosis; Avian Proteins; Chickens; Chondrocytes; Erythrocytes; Glutathione Transferase; I | 2021 |
Janus kinase/signal transducer and activator of transcription signaling pathway-related genes STAT3, SOCS3 and their role in thiram induced tibial dyschondroplasia chickens.
Topics: Animals; Apoptosis; Chickens; Chondrocytes; Down-Regulation; Growth Plate; Janus Kinases; Osteochond | 2021 |
Chlorogenic acid inhibits apoptosis in thiram-induced tibial dyschondroplasia via intrinsic pathway.
Topics: Animals; Apoptosis; Chickens; Chlorogenic Acid; Humans; Osteochondrodysplasias; Poultry Diseases; Th | 2021 |
Tibial dyschondroplasia is closely related to suppression of expression of hypoxia-inducible factors 1α, 2α, and 3α in chickens.
Topics: Animals; Avian Proteins; Basic Helix-Loop-Helix Transcription Factors; Chickens; Gene Expression Reg | 2018 |
Tibial dyschondroplasia is highly associated with suppression of tibial angiogenesis through regulating the HIF-1α/VEGF/VEGFR signaling pathway in chickens.
Topics: Altitude Sickness; Animals; Chickens; Down-Regulation; Gene Expression Regulation, Neoplastic; Hypox | 2017 |
Effect of tetramethylpyrazine on tibial dyschondroplasia incidence, tibial angiogenesis, performance and characteristics via HIF-1α/VEGF signaling pathway in chickens.
Topics: Animals; Chickens; Hypoxia-Inducible Factor 1, alpha Subunit; Incidence; Neovascularization, Patholo | 2018 |
Effect of Icariin on Tibial Dyschondroplasia Incidence and Tibial Characteristics by Regulating P2RX7 in Chickens.
Topics: Animals; Chickens; Flavonoids; Gene Expression; Growth Plate; Incidence; Male; Neovascularization, P | 2018 |
Effect of tetramethyl thiuram disulfide (thiram) in relation to tibial dyschondroplasia in chickens.
Topics: Animals; Chickens; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Neovascularization, Pathologic; | 2018 |
Identification of apoptosis-related genes in erythrocytes of broiler chickens and their response to thiram-induced tibial dyschondroplasia and recombinant glutathione-S-transferase A3 protein.
Topics: Animals; Apoptosis; Chickens; Erythrocytes; Gene Expression; Gene Expression Regulation; Genetic Pre | 2018 |
Ligustrazine recovers thiram-induced tibial dyschondroplasia in chickens: Involvement of new molecules modulating integrin beta 3.
Topics: Animals; Chickens; Gene Expression Regulation; Growth Plate; Integrin beta3; Neovascularization, Pat | 2019 |
The expression of prostaglandins-related genes in erythrocytes of broiler chicken responds to thiram-induced tibial dyschondroplasia and recombinant glutathione-S-transferase A3 protein.
Topics: Animals; Avian Proteins; Chickens; Erythrocytes; Glutathione Transferase; Mutagens; Osteochondrodysp | 2019 |
Identification of differentially expressed MiRNAs profile in a thiram-induced tibial dyschondroplasia.
Topics: Animals; Apoptosis; Chickens; Environmental Pollutants; Growth Plate; MicroRNAs; Osteochondrodysplas | 2019 |
Protective effect of Astragaloside IV to inhibit thiram-induced tibial dyschondroplasia.
Topics: Animal Feed; Animals; Antioxidants; Chickens; Cyclooxygenase 2; Enzymes; Gene Expression; Liver; Ost | 2019 |
Screening of differentially expressed genes in the growth plate of broiler chickens with tibial dyschondroplasia by microarray analysis.
Topics: Animals; Chickens; Down-Regulation; Growth Plate; Meat; Osteochondrodysplasias; Poultry Diseases; Pr | 2013 |
Expression and identification of recombinant chicken vascular endothelial growth factor in Pichia pastoris and its role in the pathogenesis of tibial dyschondroplasia.
Topics: Animals; Avian Proteins; Blood Chemical Analysis; Chick Embryo; Chickens; Chorioallantoic Membrane; | 2013 |
Differential expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in avian tibial dyschondroplasia.
Topics: Analysis of Variance; Animals; Basigin; Blotting, Western; Chickens; DNA Primers; Extracellular Matr | 2015 |
Hsp90 inhibitor celastrol reinstates growth plate angiogenesis in thiram-induced tibial dyschondroplasia.
Topics: Animals; Chickens; Growth Plate; HSP90 Heat-Shock Proteins; Male; Osteochondrodysplasias; Pentacycli | 2016 |
Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia.
Topics: Animals; Apigenin; Catechin; Chickens; Growth Plate; HSP90 Heat-Shock Proteins; Male; Osteochondrody | 2016 |
Identification of differentially expressed genes in the growth plate of broiler chickens with thiram-induced tibial dyschondroplasia.
Topics: Animal Feed; Animals; Chickens; DNA Primers; DNA, Complementary; Fungicides, Industrial; Gene Expres | 2009 |
Expression of matrix metalloproteinases during impairment and recovery of the avian growth plate.
Topics: Animals; Chickens; Gene Expression Regulation, Enzymologic; Growth Plate; In Situ Hybridization; Mat | 2009 |
The effect of inhibition of heat-shock proteins on thiram-induced tibial dyschondroplasia.
Topics: Animals; Benzoquinones; Chickens; Dose-Response Relationship, Drug; Heat-Shock Proteins; Lactams, Ma | 2012 |
Effect of thiram on avian growth plate chondrocytes in culture.
Topics: Animals; Avian Proteins; Cells, Cultured; Chickens; Chondrocytes; Fungicides, Industrial; Growth Pla | 2013 |
Changes in the tibial growth plates of chickens with thiram-induced dyschondroplasia.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Antifungal Agents; Apoptosis; Cell Proliferation; C | 2005 |
Induction of tibial dyschondroplasia in turkeys by tetramethylthiuram disulfide (thiram).
Topics: Animals; Body Weight; Chickens; Feeding Behavior; Hindlimb; Lameness, Animal; Mutagens; Osteochondro | 2007 |
An outbreak of thiram poisoning on Spanish poultry farms.
Topics: Abnormalities, Drug-Induced; Animal Feed; Animals; Chickens; Egg Shell; Food Contamination; Fungicid | 1996 |
Influence of dietary tetramethylthiuram disulfide (a fungicide) on growth and incidence of tibial dyschondroplasia in single comb White Leghorn chicks.
Topics: Animals; Bone and Bones; Chickens; Fungicides, Industrial; Male; Osteochondrodysplasias; Poultry Dis | 1986 |
Observations on several factors influencing the incidence of tibial dyschondroplasia in broiler chickens.
Topics: Animals; Chickens; Diet; Lasalocid; Monensin; Osteochondrodysplasias; Potassium; Poultry Diseases; T | 1985 |