Compounds > thiram
Page last updated: 2024-11-05

thiram and Contact Dermatitis

thiram has been researched along with Contact Dermatitis in 26 studies

Thiram: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.
thiram : An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment.

Research Excerpts

ExcerptRelevanceReference
" The sensitizing capacity of known allergens was quantified by dose-response modeling."1.31A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins. ( de Jong, WH; Slob, W; van Loveren, H; van Och, FM; Vandebriel, RJ, 2000)
"The results suggested that contact sensitivity for weak sensitizers can be evaluated by this modified lymphocyte transformation test, especially when lymph node cells were co-cultured with EC."1.29Evaluation of contact sensitivity to formaldehyde and tetramethylthiuram monosulfide using a modified lymphocyte transformation test. ( Inagaki, H; Li, Q; Li, YJ; Minami, M; Wang, ZY, 1995)
"Allergic contact dermatitis is less common, occurring in 2 of the 100 patients."1.27Cutaneous reactions to surgical preparations and dressings. ( Marks, JG; Rainey, MA, 1984)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199017 (65.38)18.7374
1990's5 (19.23)18.2507
2000's3 (11.54)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ozkaya, E1
Uter, W1
Hegewald, J1
Pfahlberg, A1
Lessmann, H1
Schnuch, A1
Gefeller, O1
van Och, FM2
Vandebriel, RJ2
De Jong, WH2
van Loveren, H2
BANDMANN, HJ1
NASEMANN, T1
SHELLEY, WB1
Agathos, M1
Bernecker, HA1
Van Ketel, WG2
Marks, JG1
Rainey, MA1
Goitre, M1
Bedello, PG1
Cane, D1
Li, Q1
Wang, ZY1
Inagaki, H1
Li, YJ1
Minami, M1
Knudsen, BB1
Menné, T1
Pagliaro, JA1
Jones, SK1
Slob, W1
Foussereau, J1
Cavelier, C1
Weinstein, LH1
Fellner, MJ1
Marzulli, FN1
Maibach, HI1
Penneys, NS1
Edwards, LS1
Katsikas, JL1
Kimber, I1
Quirke, S1
Cumberbatch, M1
Ashby, J1
Paton, D1
Aldridge, RD1
Hunter, JA1
Beck, MH1
Cabrita, JC1
Gonçalo, M1
Azenha, A1
Gonçalo, S1
Dooms-Goossens, AE1
Debusschere, KM1
Gevers, DM1
Dupré, KM1
Degreef, HJ1
Loncke, JP1
Snauwaert, JE1
Pock-Steen, B1
Kruis-de Vries, MH1
Coenraads, PJ1
Nater, JP1
Baer, RL1
Ramsey, DL1
Biondi, E1
Wilson, HT1

Reviews

2 reviews available for thiram and Contact Dermatitis

ArticleYear
Contact allergy: predictive testing in man.
    Contact dermatitis, 1976, Volume: 2, Issue:1

    Topics: Allergens; Balsams; Benzocaine; Chromium; Cosmetics; Dermatitis, Contact; Ethylenediamines; Formalde

1976
Contact dermatitis caused by airborne agents. A review and case reports.
    Journal of the American Academy of Dermatology, 1986, Volume: 15, Issue:1

    Topics: Adult; Aged; Air Pollutants; Captan; Cobalt; Dermatitis, Contact; Dermatitis, Occupational; Detergen

1986

Other Studies

24 other studies available for thiram and Contact Dermatitis

ArticleYear
'Passe-partout effect' in positive patch test reactions: a novel pattern of edge effect.
    Contact dermatitis, 2009, Volume: 61, Issue:4

    Topics: Dermatitis, Contact; Diamines; Female; Humans; Irritants; Male; Middle Aged; p-Aminoazobenzene; Patc

2009
Contact allergy to thiurams: multifactorial analysis of clinical surveillance data collected by the IVDK network.
    International archives of occupational and environmental health, 2010, Volume: 83, Issue:6

    Topics: Adult; Causality; Dermatitis, Contact; Europe; Female; Fungicides, Industrial; Humans; Male; Middle

2010
Effect of prolonged exposure to low antigen concentration for sensitization.
    Toxicology, 2003, Feb-14, Volume: 184, Issue:1

    Topics: Allergens; Animals; Antigens; Benzocaine; Cell Division; Dermatitis, Contact; Dinitrochlorobenzene;

2003
[Pseudopolyvalent contact eczema in sensitization against tetramethylthiuramdisulfide (TMTD) contained in rubber and in newest drugs].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1958, Volume: 9, Issue:1

    Topics: Dermatitis; Dermatitis, Contact; Disulfiram; Humans; Rubber; Thiram

1958
GOLF-COURSE DERMATITIS DUE TO THIRAM FUNGICIDE. CROSS-HAZARDS OF ALCOHOL, DISULFIRAM, AND RUBBER.
    JAMA, 1964, May-04, Volume: 188

    Topics: Alcoholic Beverages; Antifungal Agents; Dermatitis; Dermatitis, Contact; Disulfiram; Ethanol; Golf;

1964
[Hand dermatitis in medical personnel].
    Dermatosen in Beruf und Umwelt. Occupation and environment, 1982, Volume: 30, Issue:2

    Topics: Dermatitis, Contact; Dermatitis, Occupational; Female; Formaldehyde; Hand Dermatoses; Health Occupat

1982
Contact urticaria from rubber gloves after dermatitis from thiurams.
    Contact dermatitis, 1984, Volume: 11, Issue:5

    Topics: Adult; Clothing; Dermatitis, Contact; Hand Dermatoses; Humans; Male; Thiocarbamates; Thiram; Urticar

1984
Cutaneous reactions to surgical preparations and dressings.
    Contact dermatitis, 1984, Volume: 10, Issue:1

    Topics: Adult; Bandages; Biological Dressings; Dermatitis, Contact; Female; Humans; Male; Middle Aged; Occlu

1984
Allergic dermatitis and oral challenge to tetramethylthiuram disulphide.
    Contact dermatitis, 1981, Volume: 7, Issue:5

    Topics: Administration, Oral; Dermatitis, Contact; Female; Humans; Middle Aged; Thiocarbamates; Thiram

1981
Evaluation of contact sensitivity to formaldehyde and tetramethylthiuram monosulfide using a modified lymphocyte transformation test.
    Toxicology, 1995, Dec-15, Volume: 104, Issue:1-3

    Topics: Analysis of Variance; Animals; Cells, Cultured; Dermatitis, Contact; Dose-Response Relationship, Dru

1995
Elicitation thresholds for thiuram mix using petrolatum and ethanol/sweat as vehicles.
    Contact dermatitis, 1996, Volume: 34, Issue:6

    Topics: Allergens; Antifungal Agents; Dermatitis, Contact; Disulfiram; Dose-Response Relationship, Drug; Emo

1996
Recurrent erythrodermic psoriasis in a thiuram-allergic patient due to contact with nurses' rubber gloves.
    The British journal of dermatology, 1999, Volume: 140, Issue:3

    Topics: Dermatitis, Contact; Female; Gloves, Surgical; Humans; Latex Hypersensitivity; Middle Aged; Psoriasi

1999
A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins.
    Toxicology, 2000, Apr-20, Volume: 146, Issue:1

    Topics: Allergens; Animals; Benzocaine; Benzothiazoles; Dermatitis, Contact; Diethylamines; Dinitrochloroben

2000
[Has N-isopropyl-N'-phenylparaphenylenediamine a place among standard allergens? Importance of this allergen in rubber intolerance].
    Dermatologica, 1977, Volume: 155, Issue:3

    Topics: Allergens; Chemical Phenomena; Chemistry; Dermatitis, Contact; Dermatitis, Occupational; Humans; Mer

1977
Rubber band dermatitis.
    International journal of dermatology, 1979, Volume: 18, Issue:7

    Topics: Dermatitis, Contact; Female; Humans; Middle Aged; Rubber; Thiocarbamates; Thiram

1979
Allergic contact sensitivity to thiuram compounds in a hemodialysis unit.
    Archives of dermatology, 1976, Volume: 112, Issue:6

    Topics: Aged; Dermatitis, Atopic; Dermatitis, Contact; Female; Humans; Kidneys, Artificial; Male; Middle Age

1976
Thiuram-mix.
    Contact dermatitis, 1976, Volume: 2, Issue:4

    Topics: Dermatitis, Contact; Humans; Patch Tests; Thiocarbamates; Thiram

1976
The frequency of contact sensitivity in North America 1972-74.
    Contact dermatitis, 1975, Volume: 1, Issue:5

    Topics: Balsams; Dermatitis, Contact; Epoxy Resins; Ethylenediamines; Humans; Nickel; North America; Patch T

1975
Lymphocyte transformation and thiuram sensitization.
    Contact dermatitis, 1991, Volume: 24, Issue:3

    Topics: Cell Division; Cells, Cultured; Dermatitis, Contact; Dimethylamines; Humans; Leukocytes, Mononuclear

1991
Allergic contact dermatitis of the eyelids from rubber chemicals.
    Contact dermatitis, 1991, Volume: 24, Issue:2

    Topics: Adult; Dermatitis, Contact; Eyelids; Facial Dermatoses; Female; Humans; Rubber; Thiram

1991
Contact allergy to Nobecutan.
    Contact dermatitis, 1988, Volume: 18, Issue:1

    Topics: Acrylic Resins; Dermatitis, Contact; Drug Combinations; Female; Humans; Middle Aged; Occlusive Dress

1988
Allergic contact dermatitis due to rubber chemicals in haemodialysis equipment.
    Contact dermatitis, 1987, Volume: 17, Issue:5

    Topics: Adult; Aged; Carbamates; Dermatitis, Contact; Humans; Middle Aged; Patch Tests; Renal Dialysis; Rubb

1987
The most common contact allergens 1968-1970.
    Archives of dermatology, 1973, Volume: 108, Issue:1

    Topics: Allergens; Aminobenzoates; Aniline Compounds; Azo Compounds; Balsams; Chromates; Chrysanthemum ciner

1973
Rubber dermatitis. An investigation of 106 cases of contact dermatitis caused by rubber.
    The British journal of dermatology, 1969, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Clothing; Dermatitis, Contact; Female; Humans; Male; Middle Aged; Ru

1969