thiram has been researched along with Chondrodystrophic Myotonia in 57 studies
Thiram: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.
thiram : An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiram (50 mg/kg) was added to the diet during 11-14 days to induce TD." | 3.30 | Effects of cold stress on growth performance, carcass traits and tibia attributes in broiler chickens with thiram-induced dyschondroplasia. ( Hassanabadi, A; Saeedi, S; Zaeemi, M, 2023) |
| "Tibial dyschondroplasia (TD) is an intractable avian cartilage disease in which proximal growth plates of tibia lack blood vessels and contain nonviable cells, and it leads to the inflammatory response." | 3.01 | Glutathione-S-transferase A3 protein suppresses thiram-induced tibial dyschondroplasia by regulating prostaglandin-related genes expression. ( Jahejo, AR; Jia, YF; Li, X; Li, Z; Ning, GB; Niu, S; Tian, WX; Tian, ZX; Yang, SX; Zhang, D; Zhang, N; Zhang, YY, 2021) |
| "Tibial dyschondroplasia (TD) is a bone defect of broilers and other poultry birds that disturbs growth plate and it causes lameness." | 2.87 | Clinical efficiency and safety of Hsp90 inhibitor Novobiocin in avian tibial dyschondroplasia. ( Ahmed, N; Arain, MA; Chachar, B; Han, Z; Huang, S; Iqbal, MK; Li, J; Mehmood, K; Nabi, F; Rehman, MU; Shahzad, M; Zhang, H, 2018) |
| " A review of the literature has shown that thiram can affect different organs in animals and its toxic mechanisms can be elucidated in more detail at molecular level." | 2.82 | Thiram exposure in environment: A critical review on cytotoxicity. ( Iqbal, M; Li, Y; Liu, K; Tang, Z; Zhang, H, 2022) |
| "Tibial dyschondroplasia (TD) is a developmental cartilaginous disease due to thiram toxicity." | 1.91 | Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens. ( Ding, Y; Kulyar, MF; Li, J; Mo, Q; Yao, W; Zhu, H, 2023) |
| "Tibial dyschondroplasia (TD) with multiple incentives is a metabolic skeletal disease that occurs in fast-growing broilers." | 1.91 | Gut microbiome dysregulation drives bone damage in broiler tibial dyschondroplasia by disrupting glucose homeostasis. ( Chen, P; Ding, WL; He, YF; Huang, SC; Lin, LX; Liu, F; Liu, KL; Shaukat, A; Tong, X; Xie, JF; Xu, TT; Yue, K; Zhang, C; Zhang, CD; Zhang, HY, 2023) |
| "Avian tibial dyschondroplasia (TD) is a skeletal disease affecting fast growing chickens, resulting in non-mineralized avascular cartilage." | 1.91 | Baicalin inhibits apoptosis and enhances chondrocyte proliferation in thiram-induced tibial dyschondroplasia in chickens by regulating Bcl-2/Caspase-9 and Sox-9/Collagen-II expressions. ( Iqbal, M; Kulyar, MF; Li, J; Mehmood, K; Mo, Q; Nawaz, S; Qamar, H; Shahzad, M; Waqas, M; Zeng, Z, 2023) |
| "Tibial dyschondroplasia (TD) is a bone disorder in which dead chondrocytes accumulate as a result of apoptosis and non-vascularization in the tibial bone of broiler chickens." | 1.72 | Transcriptome-based biomarker gene screening and evaluation of the extracellular fatty acid-binding protein (Ex-FABP) on immune and angiogenesis-related genes in chicken erythrocytes of tibial dyschondroplasia. ( Bukhari, SAR; Jahejo, AR; Kalhoro, NH; Leghari, IH; Li, Z; Liu, WZ; Rajput, N; Raza, SHA; Tian, WX, 2022) |
| "Manganese (Mn) is an essential microelement for broiler breeding and its deficiency causes tibial dyschondroplasia (TD)." | 1.72 | HIF-1α upregulation exerts the antagonistic effect against angiogenesis inhibition in manganese deficiency-induced tibial dyschondroplasia of broiler chicks. ( Dong, PF; Jin, C; Lu, L; Wang, ZY, 2022) |
| "Thiram is a dithiocarbamate pesticide widely used in agriculture as a fungicide for storing grains to prevent fungal diseases." | 1.72 | Sodium butyrate ameliorates thiram-induced tibial dyschondroplasia and gut microbial dysbiosis in broiler chickens. ( Ding, Y; Fu, Y; Gong, S; He, Y; Iqbal, M; Kulyar, MF; Li, F; Li, J; Mo, Q; Quan, C; Xiao, Y; Yao, W; Zhang, Y, 2022) |
| "Tibial dyschondroplasia (TD) is a leg disorder caused by the abnormal development of the tibia in fast-growing poultry." | 1.62 | Lactobacillus rhamnosus JYLR-005 Prevents Thiram-Induced Tibial Dyschondroplasia by Enhancing Bone-Related Growth Performance in Chickens. ( Cao, QQ; Fu, P; Huang, SC; Kong, A; Liu, DY; Liu, F; Rehman, MU; Tao, KS; Tong, ZX; Wang, XB, 2021) |
| "Pathogenicity of tibial dyschondroplasia (TD) in broiler chickens is not detected yet." | 1.62 | Janus kinase/signal transducer and activator of transcription signaling pathway-related genes STAT3, SOCS3 and their role in thiram induced tibial dyschondroplasia chickens. ( Ahmed, S; Chen, SM; Jahejo, AR; Nabi, F; Ning, GB; Raza, SHA; Tian, WX; Yu, J; Zhang, CL; Zhang, D; Zhao, JF, 2021) |
| "Tibial dyschondroplasia (TD) is a metabolic disease of young poultry that affects bone andcartilage's growth." | 1.62 | Cluster of differentiation 147 (CD147) expression is linked with thiram induced chondrocyte's apoptosis via Bcl-2/Bax/Caspase-3 signalling in tibial growth plate under chlorogenic acid repercussion. ( Ding, Y; Du, H; Huachun, P; Kulyar, MF; Li, A; Li, J; Li, K; Mehmood, K; Waqas, M; Yao, W; Zhang, L, 2021) |
| "Thiram is a sort of chemical used for pesticide and fungicide." | 1.62 | Chlorogenic acid inhibits apoptosis in thiram-induced tibial dyschondroplasia via intrinsic pathway. ( Guo, K; Kulyar, MF; Li, J; Liu, J; Luo, B; Waqas, M; Zhang, J, 2021) |
| "Thiram is a widely known tibial dyschondroplasia (TD) inducer." | 1.56 | Identification and expression analysis of microRNAs in tibial growth plate of chicken through thiram toxicity. ( Iqbal, M; Li, A; Li, J; Li, Z; Lian, Y; Mehmood, K; Wang, Y; Zhang, H; Zhang, J, 2020) |
| "1." | 1.56 | Transcriptome-based screening of intracellular pathways and angiogenesis related genes at different stages of thiram induced tibial lesions in broiler chickens. ( Chen, HC; Jahejo, AR; Khan, A; Mangi, RA; Niu, S; Qadir, MF; Tian, WX; Zhang, D, 2020) |
| "Tibial dyschondroplasia (TD) is a skeletal deformity disease in broilers that occurs when vascularization in the growth plate (GP) is below normal." | 1.56 | Recombinant glutathione-S-transferase A3 protein regulates the angiogenesis-related genes of erythrocytes in thiram induced tibial lesions. ( Ahsan, A; Jahejo, AR; Kalhoro, DH; Kashif, J; Khan, A; Mangi, RA; Niu, S; Qadir, MF; Qiao, ML; Rajput, N; Tian, WX; Zhang, D, 2020) |
| "Tibial Dyschondroplasia (TD), a metabolic disease of fast growing poultry birds that effects the growth of bone and cartilage, is characterized by anorexia, mental depression and lameness." | 1.51 | Recovery of chicken growth plate by TanshinoneⅡA through wnt/β-catenin pathway in thiram-induced Tibial Dyschondroplasia. ( Shen, Y; Tong, X; Yang, H; Zhang, H; Zhang, J, 2019) |
| "Tibial dyschondroplasia (TD) is a type of bone deformity found in fast-growing chickens, which induce inflammatory responses." | 1.51 | The expression of prostaglandins-related genes in erythrocytes of broiler chicken responds to thiram-induced tibial dyschondroplasia and recombinant glutathione-S-transferase A3 protein. ( Chen, HC; Gao, RK; Gao, SM; Gao, WW; Hao, WF; Huo, NR; Jahejo, AR; Jia, FJ; Li, GL; Li, JH; Li, X; Ma, HL; Ning, GB; Niu, S; Tian, WX; Wang, CX; Yan, F; Zhang, D; Zhao, YJ, 2019) |
| "Tibial dyschondroplasia (TD) is most the common tibiotarsal bone disease in rapidly growing birds throughout the world." | 1.51 | Protective effect of Astragaloside IV to inhibit thiram-induced tibial dyschondroplasia. ( Jiang, X; Lei, L; Li, A; Li, J; Mehmood, K; Qamar, H; Wang, Y; Waqas, M; Yao, W; Zhang, H; Zhang, L, 2019) |
| "Chlorogenic acid (CGA) is a widely applied traditional Chinese medicine ingredient which can be used for the treatment of osteoporosis." | 1.51 | Chlorogenic Acid Alleviates Thiram-Induced Tibial Dyschondroplasia by Modulating Caspases, BECN1 Expression and ECM Degradation. ( Huang, S; Jiang, X; Li, J; Mehmood, K; Tong, X; Zhang, H; Zhang, J; Zhang, L, 2019) |
| "Tibial dyschondroplasia (TD) cases has not been reported in Tibetan chickens (TBCs), but it is commonly seen in commercial broilers characterized by lameness." | 1.48 | Tibial dyschondroplasia is closely related to suppression of expression of hypoxia-inducible factors 1α, 2α, and 3α in chickens. ( Huang, S; Iqbal, MK; Li, J; Luo, H; Mehmood, K; Qiu, G; Rehman, MU; Zhang, H, 2018) |
| "Tibial dyschondroplasia (TD) is a disease of rapid growing chickens that occurs in many avian species; it is characterized by nonvascular and nonmineralized growth plates, along with tibia bone deformation and lameness." | 1.48 | Effect of Icariin on Tibial Dyschondroplasia Incidence and Tibial Characteristics by Regulating P2RX7 in Chickens. ( Iqbal, M; Jiang, X; Li, J; Li, K; Mehmood, K; Nabi, F; Rehman, MU; Tong, X; Wang, L; Wang, M; Yao, W; Zhang, H; Zhang, L, 2018) |
| "Thiram treatment significantly reduced the performance of chickens, liver index, and tibial length compared with control group." | 1.48 | Effect of tetramethyl thiuram disulfide (thiram) in relation to tibial dyschondroplasia in chickens. ( Iqbal, M; Jiang, X; Li, A; Li, J; Mehmood, K; Rehman, MU; Shen, Y; Waqas, M; Yao, W; Zhang, H, 2018) |
| "Tibial dyschondroplasia (TD) is an intractable poultry problem that is characterized by the appearance of non-vascularized and non-mineralized cartilage masses in tibial growth plates (TGPs)." | 1.46 | Tibial dyschondroplasia is highly associated with suppression of tibial angiogenesis through regulating the HIF-1α/VEGF/VEGFR signaling pathway in chickens. ( Huang, SC; Iqbal, MK; Lan, YF; Li, JK; Luo, HQ; Mehmood, K; Qiu, G; Rehman, MU; Zhang, H; Zhang, LH, 2017) |
| "Tibial dyschondroplasia (TD) is one of the common skeletal abnormalities in fast-growing birds, and it is characterized by nonvascularized, unmineralized, and nonviable cartilage in the tibial growth plate that fails to form bone." | 1.46 | In Vitro Effect of Apigenin and Danshen in Tibial Dyschondroplasia Through Inhibition of Heat-Shock Protein 90 and Vascular Endothelial Growth Factor Expressions in Avian Growth Plate Cells. ( Huang, S; Iqbal, MK; Li, J; Li, K; Mehmood, K; Nabi, F; Rehman, MU; Shahzad, M; Zhang, H; Zhang, L, 2017) |
| "Tibial dyschondroplasia (TD) is an important long bone defect of broiler chickens that disturbs the proximal growth plate and is characterized by non-vascularized cartilage, a distended growth plate and lameness." | 1.43 | Hsp90 inhibitor celastrol reinstates growth plate angiogenesis in thiram-induced tibial dyschondroplasia. ( Han, Z; Iqbal, MK; Li, J; Li, K; Liu, J; Nabi, F; Shahzad, M; Zhang, D, 2016) |
| "Tibial dyschondroplasia (TD) is an important tibiotarsal bone disorder characterized by an avascular and nonmineralized growth plate; it is attributed to abnormal differentiation of chondrocytes and causes lameness." | 1.43 | Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia. ( Iqbal, MK; Li, J; Liu, J; Nabi, F; Rehman, MU; Tahir, AH; Zhang, H, 2016) |
| "Tibial dyschondroplasia (TD) is an avian bone disorder of different aetiologies that may be associated with lameness." | 1.42 | Differential expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in avian tibial dyschondroplasia. ( Gao, J; Li, J; Li, K; Liu, J; Nabi, F; Shahzad, M; Wang, Z; Zhang, D, 2015) |
| "Tibial dyschondroplasia (TD) is a common skeletal disorder in broiler chickens." | 1.39 | Screening of differentially expressed genes in the growth plate of broiler chickens with tibial dyschondroplasia by microarray analysis. ( Bi, DR; Guo, DZ; Li, HQ; Li, JK; Ning, GB; Pan, SY; Qiao, JG; Qin, P; Tian, WX; Wang, R, 2013) |
| "In thiram-treated broilers at 15 d old, the chVEGF proteins upregulated the expression of MMP-13 and Runx2, and had different effects on type X collagen and Bcl-2 expression at different dosages." | 1.39 | Expression and identification of recombinant chicken vascular endothelial growth factor in Pichia pastoris and its role in the pathogenesis of tibial dyschondroplasia. ( Deng, YF; Hou, JF; Zhang, JP; Zhou, ZL, 2013) |
| "Thiram is a dithiocarbamate pesticide that causes tibial dyschondroplasia (TD), a growth plate defect, in poultry." | 1.39 | Effect of thiram on avian growth plate chondrocytes in culture. ( Lay, JO; Liyanage, R; Rasaputra, KS; Rath, NC; Slavik, MF, 2013) |
| "Tibial dyschondroplasia (TD) is a skeletal abnormality that can cause economic losses and animal welfare concerns." | 1.38 | The effect of inhibition of heat-shock proteins on thiram-induced tibial dyschondroplasia. ( Genin, O; Hasdai, A; Pines, M; Shinder, D, 2012) |
| "Tibial dyschondroplasia (TD) is characterized by expansion of the proximal growth plates of the tibiotarsus that fail to form bone, lack blood vessels, and contain non-viable cells." | 1.35 | Identification of differentially expressed genes in the growth plate of broiler chickens with thiram-induced tibial dyschondroplasia. ( Bi, DR; Guo, DZ; Li, JK; Pan, SY; Qin, P; Tian, WX; Zhang, WP; Zhang, YH, 2009) |
| "Tibial dyschondroplasia (TD) is a prevalent skeletal abnormality associated with rapid growth rate in many avian species." | 1.35 | Expression of matrix metalloproteinases during impairment and recovery of the avian growth plate. ( Dan, H; Hisdai, A; Monsonego Ornan, E; Sela-Donenfeld, D; Simsa-Maziel, S, 2009) |
| "Tibial dyschondroplasia (TD) is a prevalent skeletal abnormality associated with rapid growth rate in many avian species; it causes enormous economic losses and is an animal welfare problem." | 1.34 | Induction of tibial dyschondroplasia in turkeys by tetramethylthiuram disulfide (thiram). ( Dan, H; Hasdai, A; Ornan, EM; Simsa, S, 2007) |
| "Tibial dyschondroplasia (TD), a major metabolic cartilage disease in poultry, is characterized by the distension of proximal growth plates of tibia that fail to form bone, lack blood vessels, and contain nonviable cells." | 1.34 | Thiram-induced changes in the expression of genes relating to vascularization and tibial dyschondroplasia. ( Huff, GR; Huff, WE; Rath, NC, 2007) |
| "Tibial dyschondroplasia (TD) is a metabolic cartilage disease of young poultry in which endochondral bone formation is disrupted leading to the retention of a non-calcified, avascular plug of cartilage in the tibial growth plate." | 1.33 | Changes in the tibial growth plates of chickens with thiram-induced dyschondroplasia. ( Balog, JM; Huff, GR; Huff, WE; Rath, NC; Richards, MP, 2005) |
| "When thiuram was added to the tibial dyschondroplasia-inducing diet, it also caused a decrease in bone ash and in the total and ultrafilterable plasma calcium." | 1.27 | Observations on several factors influencing the incidence of tibial dyschondroplasia in broiler chickens. ( Edwards, HM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.26) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (12.28) | 29.6817 |
| 2010's | 22 (38.60) | 24.3611 |
| 2020's | 25 (43.86) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, K | 1 |
| Li, Y | 4 |
| Iqbal, M | 11 |
| Tang, Z | 2 |
| Zhang, H | 16 |
| Liu, Y | 2 |
| Yi, J | 1 |
| Hussain, R | 1 |
| Zhu, S | 1 |
| Ouyang, Z | 1 |
| Mehmood, K | 17 |
| Hu, L | 1 |
| Pan, J | 1 |
| Jahejo, AR | 10 |
| Bukhari, SAR | 1 |
| Rajput, N | 2 |
| Kalhoro, NH | 2 |
| Leghari, IH | 1 |
| Raza, SHA | 3 |
| Li, Z | 6 |
| Liu, WZ | 1 |
| Tian, WX | 12 |
| Saeedi, S | 1 |
| Hassanabadi, A | 1 |
| Zaeemi, M | 1 |
| Kulyar, MF | 11 |
| Mo, Q | 8 |
| Yao, W | 12 |
| Ding, Y | 9 |
| Yan, Z | 1 |
| Du, H | 3 |
| Pan, H | 4 |
| Li, K | 7 |
| Gao, J | 2 |
| Shahzad, M | 7 |
| Mansoor, MK | 1 |
| Waqas, M | 11 |
| Akhtar, M | 1 |
| Bhutta, ZA | 1 |
| Li, J | 28 |
| Lu, L | 1 |
| Jin, C | 1 |
| Dong, PF | 1 |
| Wang, ZY | 1 |
| Zhang, CL | 2 |
| Nabi, F | 9 |
| Shah, QA | 1 |
| Bhutto, ZA | 1 |
| Zhao, JF | 2 |
| Yu, J | 2 |
| Ning, GB | 8 |
| Zhang, D | 11 |
| Chen, SM | 2 |
| Lu, Y | 1 |
| Xu, H | 1 |
| Jiang, Y | 1 |
| Hu, Z | 1 |
| Du, R | 1 |
| Zhao, X | 1 |
| Tian, Y | 1 |
| Zhu, Q | 1 |
| Zhang, Y | 6 |
| Wang, Y | 6 |
| He, Y | 1 |
| Quan, C | 4 |
| Gong, S | 1 |
| Li, F | 1 |
| Fu, Y | 1 |
| Xiao, Y | 1 |
| Zhang, L | 8 |
| Zhu, H | 2 |
| Xu, TT | 1 |
| Chen, P | 1 |
| Zhang, CD | 1 |
| Shaukat, A | 1 |
| Lin, LX | 1 |
| Yue, K | 1 |
| Ding, WL | 1 |
| Tong, X | 6 |
| Liu, KL | 1 |
| He, YF | 1 |
| Xie, JF | 1 |
| Liu, F | 2 |
| Zhang, C | 1 |
| Zhang, HY | 1 |
| Huang, SC | 3 |
| Hong, J | 1 |
| Loon, KS | 1 |
| Nawaz, S | 2 |
| Zeng, Z | 1 |
| Qamar, H | 5 |
| Yang, H | 2 |
| Zhang, J | 7 |
| Shen, Y | 2 |
| Niu, S | 7 |
| Khan, A | 7 |
| Mangi, RA | 3 |
| Qadir, MF | 3 |
| Li, JH | 3 |
| Li, A | 7 |
| Lian, Y | 1 |
| Jiang, X | 8 |
| Chen, HC | 3 |
| Kashif, J | 1 |
| Kalhoro, DH | 1 |
| Qiao, ML | 1 |
| Ahsan, A | 2 |
| Kong, A | 1 |
| Fu, P | 1 |
| Cao, QQ | 1 |
| Tao, KS | 1 |
| Liu, DY | 1 |
| Wang, XB | 1 |
| Tong, ZX | 1 |
| Rehman, MU | 10 |
| Jia, FJ | 3 |
| Shah, MA | 1 |
| Yin, JJ | 1 |
| Li, X | 2 |
| Zhang, N | 2 |
| Yang, SX | 1 |
| Jia, YF | 1 |
| Zhang, YY | 1 |
| Tian, ZX | 1 |
| Ahmed, S | 1 |
| Huachun, P | 1 |
| Luo, B | 1 |
| Liu, J | 4 |
| Guo, K | 1 |
| Huang, S | 4 |
| Qiu, G | 2 |
| Luo, H | 2 |
| Iqbal, MK | 8 |
| Lan, YF | 1 |
| Luo, HQ | 1 |
| Zhang, LH | 1 |
| Li, JK | 3 |
| Wang, L | 2 |
| Wang, M | 1 |
| Han, Z | 2 |
| Ahmed, N | 1 |
| Chachar, B | 1 |
| Arain, MA | 1 |
| Wang, CX | 2 |
| Li, HQ | 2 |
| Ma, HL | 2 |
| Hao, WF | 2 |
| Gao, WW | 2 |
| Gao, SM | 2 |
| Li, GL | 2 |
| Yan, F | 2 |
| Gao, RK | 2 |
| Zhao, YJ | 2 |
| Huo, NR | 1 |
| Lei, L | 1 |
| Qin, P | 2 |
| Wang, R | 1 |
| Qiao, JG | 1 |
| Bi, DR | 2 |
| Pan, SY | 2 |
| Guo, DZ | 2 |
| Zhang, JP | 1 |
| Deng, YF | 1 |
| Zhou, ZL | 1 |
| Hou, JF | 1 |
| Wang, Z | 1 |
| Tahir, AH | 1 |
| Zhang, WP | 1 |
| Zhang, YH | 1 |
| Dan, H | 2 |
| Simsa-Maziel, S | 1 |
| Hisdai, A | 1 |
| Sela-Donenfeld, D | 1 |
| Monsonego Ornan, E | 1 |
| Genin, O | 1 |
| Hasdai, A | 2 |
| Shinder, D | 1 |
| Pines, M | 1 |
| Rasaputra, KS | 1 |
| Liyanage, R | 1 |
| Lay, JO | 1 |
| Slavik, MF | 1 |
| Rath, NC | 4 |
| Richards, MP | 1 |
| Huff, WE | 3 |
| Huff, GR | 3 |
| Balog, JM | 1 |
| Kannan, L | 1 |
| Pillai, PB | 1 |
| Horst, RL | 1 |
| Emmert, JL | 1 |
| Simsa, S | 1 |
| Ornan, EM | 1 |
| Bi, D | 1 |
| Pan, S | 1 |
| Edwards, HM | 2 |
| Veltmann, JR | 1 |
| Linton, SS | 1 |
1 review available for thiram and Chondrodystrophic Myotonia
| Article | Year |
|---|---|
Thiram exposure in environment: A critical review on cytotoxicity.
Topics: Animals; Chickens; Osteochondrodysplasias; Phosphatidylinositol 3-Kinases; Poultry Diseases; Thiram | 2022 |
6 trials available for thiram and Chondrodystrophic Myotonia
| Article | Year |
|---|---|
Residue of thiram in food, suppresses immune system stress signals and disturbs sphingolipid metabolism in chickens.
Topics: Animals; bcl-2-Associated X Protein; Beclin-1; Chickens; Endothelial Cells; Mice; Osteochondrodyspla | 2022 |
Effects of cold stress on growth performance, carcass traits and tibia attributes in broiler chickens with thiram-induced dyschondroplasia.
Topics: Animals; Chickens; Cold-Shock Response; Male; Osteochondrodysplasias; Poultry Diseases; Thiram; Tibi | 2023 |
Glutathione-S-transferase A3 protein suppresses thiram-induced tibial dyschondroplasia by regulating prostaglandin-related genes expression.
Topics: Animals; Chickens; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Male; Osteochon | 2021 |
Clinical efficiency and safety of Hsp90 inhibitor Novobiocin in avian tibial dyschondroplasia.
Topics: Animals; Chickens; Enzyme Inhibitors; Gene Expression Regulation; Growth Plate; HSP90 Heat-Shock Pro | 2018 |
Evaluation of the efficacy of vitamin D3 or its metabolites on thiram-induced tibial dyschondroplasia in chickens.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Bone and Bones; Calci | 2007 |
Effect of diet with thiram on liver antioxidant capacity and tibial dyschondroplasia in broilers.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Chickens; Diet; Glut | 2007 |
50 other studies available for thiram and Chondrodystrophic Myotonia
| Article | Year |
|---|---|
Transcriptome-based biomarker gene screening and evaluation of the extracellular fatty acid-binding protein (Ex-FABP) on immune and angiogenesis-related genes in chicken erythrocytes of tibial dyschondroplasia.
Topics: Animals; Biomarkers; Chickens; Erythrocytes; Fatty Acid-Binding Proteins; Growth Plate; Neovasculari | 2022 |
Chlorogenic acid suppresses miR-460a in the regulation of Bcl-2, causing interleukin-1β reduction in thiram exposed chondrocytes via caspase-3/caspase-7 pathway.
Topics: Apoptosis; Caspase 3; Caspase 7; Chlorogenic Acid; Chondrocytes; Humans; Inflammasomes; Interleukin- | 2022 |
HIF-1α upregulation exerts the antagonistic effect against angiogenesis inhibition in manganese deficiency-induced tibial dyschondroplasia of broiler chicks.
Topics: Animals; Chickens; Manganese; Osteochondrodysplasias; Poultry Diseases; Thiram; Tibia; Up-Regulation | 2022 |
Screening of Proliferation-Related Genes and Pathological Changes in Thiram-Induced Tibial Dyschondroplasia.
Topics: Animals; Cell Proliferation; Chickens; Growth Plate; Osteochondrodysplasias; Poultry Diseases; Proli | 2022 |
Comprehensive analysis of differently expression mRNA and non-coding RNAs, and their regulatory mechanisms on relationship in thiram-induced tibial dyschondroplasia in chicken.
Topics: Animals; Chickens; Gene Regulatory Networks; MicroRNAs; Osteochondrodysplasias; RNA, Circular; RNA, | 2022 |
Sodium butyrate ameliorates thiram-induced tibial dyschondroplasia and gut microbial dysbiosis in broiler chickens.
Topics: Animals; beta Catenin; Butyric Acid; Chickens; Core Binding Factor Alpha 1 Subunit; Dysbiosis; Ecosy | 2022 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Topics: Animals; Chickens; Hyperglycemia; Osteochondrodysplasias; Pancreas; Proteomics; Thiram | 2023 |
Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens.
Topics: Animals; Apoptosis; Chickens; Chondrocytes; Ginsenosides; Humans; Osteochondrodysplasias; Thiram | 2023 |
Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens.
Topics: Animals; Apoptosis; Chickens; Chondrocytes; Ginsenosides; Humans; Osteochondrodysplasias; Thiram | 2023 |
Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens.
Topics: Animals; Apoptosis; Chickens; Chondrocytes; Ginsenosides; Humans; Osteochondrodysplasias; Thiram | 2023 |
Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens.
Topics: Animals; Apoptosis; Chickens; Chondrocytes; Ginsenosides; Humans; Osteochondrodysplasias; Thiram | 2023 |
Gut microbiome dysregulation drives bone damage in broiler tibial dyschondroplasia by disrupting glucose homeostasis.
Topics: Animals; Chickens; Gastrointestinal Microbiome; Glucose; Homeostasis; Osteochondrodysplasias; RNA, R | 2023 |
The Effect of miR-140-5p with HDAC4 towards Growth and Differentiation Signaling of Chondrocytes in Thiram-Induced Tibial Dyschondroplasia.
Topics: Cell Differentiation; Chondrocytes; Histone Deacetylases; Humans; MicroRNAs; Osteochondrodysplasias; | 2023 |
Baicalin inhibits apoptosis and enhances chondrocyte proliferation in thiram-induced tibial dyschondroplasia in chickens by regulating Bcl-2/Caspase-9 and Sox-9/Collagen-II expressions.
Topics: Animals; Apoptosis; Caspase 9; Cell Proliferation; Chickens; Chondrocytes; Lameness, Animal; Neovasc | 2023 |
Recovery of chicken growth plate by TanshinoneⅡA through wnt/β-catenin pathway in thiram-induced Tibial Dyschondroplasia.
Topics: Abietanes; Animals; beta Catenin; Chickens; Growth Plate; Osteochondrodysplasias; Poultry Diseases; | 2019 |
Transcriptome analysis of MAPK signaling pathway and associated genes to angiogenesis in chicken erythrocytes on response to thiram-induced tibial lesions.
Topics: Animals; Chickens; Erythrocytes; Fungicides, Industrial; Gene Expression Profiling; MAP Kinase Signa | 2019 |
Identification and expression analysis of microRNAs in tibial growth plate of chicken through thiram toxicity.
Topics: Animals; Chickens; Fungicides, Industrial; Growth Plate; MicroRNAs; Osteochondrodysplasias; Poultry | 2020 |
Puerarin enhance vascular proliferation and halt apoptosis in thiram-induced avian tibial dyschondroplasia by regulating HIF-1α, TIMP-3 and BCL-2 expressions.
Topics: Animals; Antioxidants; Apoptosis; Cell Proliferation; Chickens; Fungicides, Industrial; Glutathione | 2020 |
Transcriptome-based screening of intracellular pathways and angiogenesis related genes at different stages of thiram induced tibial lesions in broiler chickens.
Topics: Animals; Chickens; Gene Ontology; Neovascularization, Physiologic; Osteochondrodysplasias; Poultry D | 2020 |
Ameliorative effect of naringin against thiram-induced tibial dyschondroplasia in broiler chicken.
Topics: Animals; Chickens; Flavanones; Osteochondrodysplasias; Poultry Diseases; Thiram; Tibia | 2020 |
Recombinant glutathione-S-transferase A3 protein regulates the angiogenesis-related genes of erythrocytes in thiram induced tibial lesions.
Topics: Animals; Chickens; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Growth Plate; I | 2020 |
Lactobacillus rhamnosus JYLR-005 Prevents Thiram-Induced Tibial Dyschondroplasia by Enhancing Bone-Related Growth Performance in Chickens.
Topics: Animals; Chickens; Lacticaseibacillus rhamnosus; Osteochondrodysplasias; Poultry Diseases; Thiram; T | 2021 |
Screening of toll-like receptor signaling pathway-related genes and the response of recombinant glutathione S-transferase A3 protein to thiram induced apoptosis in chicken erythrocytes.
Topics: Animals; Apoptosis; Avian Proteins; Chickens; Chondrocytes; Erythrocytes; Glutathione Transferase; I | 2021 |
Janus kinase/signal transducer and activator of transcription signaling pathway-related genes STAT3, SOCS3 and their role in thiram induced tibial dyschondroplasia chickens.
Topics: Animals; Apoptosis; Chickens; Chondrocytes; Down-Regulation; Growth Plate; Janus Kinases; Osteochond | 2021 |
Cluster of differentiation 147 (CD147) expression is linked with thiram induced chondrocyte's apoptosis via Bcl-2/Bax/Caspase-3 signalling in tibial growth plate under chlorogenic acid repercussion.
Topics: Animals; Apoptosis; Basigin; bcl-2-Associated X Protein; Caspase 2; Caspase 3; Cell Differentiation; | 2021 |
Chlorogenic acid inhibits apoptosis in thiram-induced tibial dyschondroplasia via intrinsic pathway.
Topics: Animals; Apoptosis; Chickens; Chlorogenic Acid; Humans; Osteochondrodysplasias; Poultry Diseases; Th | 2021 |
Tibial dyschondroplasia is closely related to suppression of expression of hypoxia-inducible factors 1α, 2α, and 3α in chickens.
Topics: Animals; Avian Proteins; Basic Helix-Loop-Helix Transcription Factors; Chickens; Gene Expression Reg | 2018 |
Tibial dyschondroplasia is highly associated with suppression of tibial angiogenesis through regulating the HIF-1α/VEGF/VEGFR signaling pathway in chickens.
Topics: Altitude Sickness; Animals; Chickens; Down-Regulation; Gene Expression Regulation, Neoplastic; Hypox | 2017 |
In Vitro Effect of Apigenin and Danshen in Tibial Dyschondroplasia Through Inhibition of Heat-Shock Protein 90 and Vascular Endothelial Growth Factor Expressions in Avian Growth Plate Cells.
Topics: Apigenin; Avian Proteins; Chondrocytes; Cytotoxins; Growth Plate; HSP90 Heat-Shock Proteins; Medicin | 2017 |
Effect of tetramethylpyrazine on tibial dyschondroplasia incidence, tibial angiogenesis, performance and characteristics via HIF-1α/VEGF signaling pathway in chickens.
Topics: Animals; Chickens; Hypoxia-Inducible Factor 1, alpha Subunit; Incidence; Neovascularization, Patholo | 2018 |
Effect of Icariin on Tibial Dyschondroplasia Incidence and Tibial Characteristics by Regulating P2RX7 in Chickens.
Topics: Animals; Chickens; Flavonoids; Gene Expression; Growth Plate; Incidence; Male; Neovascularization, P | 2018 |
Effect of tetramethyl thiuram disulfide (thiram) in relation to tibial dyschondroplasia in chickens.
Topics: Animals; Chickens; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Neovascularization, Pathologic; | 2018 |
Identification of apoptosis-related genes in erythrocytes of broiler chickens and their response to thiram-induced tibial dyschondroplasia and recombinant glutathione-S-transferase A3 protein.
Topics: Animals; Apoptosis; Chickens; Erythrocytes; Gene Expression; Gene Expression Regulation; Genetic Pre | 2018 |
Ligustrazine recovers thiram-induced tibial dyschondroplasia in chickens: Involvement of new molecules modulating integrin beta 3.
Topics: Animals; Chickens; Gene Expression Regulation; Growth Plate; Integrin beta3; Neovascularization, Pat | 2019 |
The expression of prostaglandins-related genes in erythrocytes of broiler chicken responds to thiram-induced tibial dyschondroplasia and recombinant glutathione-S-transferase A3 protein.
Topics: Animals; Avian Proteins; Chickens; Erythrocytes; Glutathione Transferase; Mutagens; Osteochondrodysp | 2019 |
Identification of differentially expressed MiRNAs profile in a thiram-induced tibial dyschondroplasia.
Topics: Animals; Apoptosis; Chickens; Environmental Pollutants; Growth Plate; MicroRNAs; Osteochondrodysplas | 2019 |
Protective effect of Astragaloside IV to inhibit thiram-induced tibial dyschondroplasia.
Topics: Animal Feed; Animals; Antioxidants; Chickens; Cyclooxygenase 2; Enzymes; Gene Expression; Liver; Ost | 2019 |
Chlorogenic Acid Alleviates Thiram-Induced Tibial Dyschondroplasia by Modulating Caspases, BECN1 Expression and ECM Degradation.
Topics: Animals; Apoptosis; Autophagy; Beclin-1; Caspases; Chickens; Chlorogenic Acid; Extracellular Matrix; | 2019 |
Screening of differentially expressed genes in the growth plate of broiler chickens with tibial dyschondroplasia by microarray analysis.
Topics: Animals; Chickens; Down-Regulation; Growth Plate; Meat; Osteochondrodysplasias; Poultry Diseases; Pr | 2013 |
Expression and identification of recombinant chicken vascular endothelial growth factor in Pichia pastoris and its role in the pathogenesis of tibial dyschondroplasia.
Topics: Animals; Avian Proteins; Blood Chemical Analysis; Chick Embryo; Chickens; Chorioallantoic Membrane; | 2013 |
Differential expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in avian tibial dyschondroplasia.
Topics: Analysis of Variance; Animals; Basigin; Blotting, Western; Chickens; DNA Primers; Extracellular Matr | 2015 |
Hsp90 inhibitor celastrol reinstates growth plate angiogenesis in thiram-induced tibial dyschondroplasia.
Topics: Animals; Chickens; Growth Plate; HSP90 Heat-Shock Proteins; Male; Osteochondrodysplasias; Pentacycli | 2016 |
Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia.
Topics: Animals; Apigenin; Catechin; Chickens; Growth Plate; HSP90 Heat-Shock Proteins; Male; Osteochondrody | 2016 |
Identification of differentially expressed genes in the growth plate of broiler chickens with thiram-induced tibial dyschondroplasia.
Topics: Animal Feed; Animals; Chickens; DNA Primers; DNA, Complementary; Fungicides, Industrial; Gene Expres | 2009 |
Expression of matrix metalloproteinases during impairment and recovery of the avian growth plate.
Topics: Animals; Chickens; Gene Expression Regulation, Enzymologic; Growth Plate; In Situ Hybridization; Mat | 2009 |
The effect of inhibition of heat-shock proteins on thiram-induced tibial dyschondroplasia.
Topics: Animals; Benzoquinones; Chickens; Dose-Response Relationship, Drug; Heat-Shock Proteins; Lactams, Ma | 2012 |
Effect of thiram on avian growth plate chondrocytes in culture.
Topics: Animals; Avian Proteins; Cells, Cultured; Chickens; Chondrocytes; Fungicides, Industrial; Growth Pla | 2013 |
Changes in the tibial growth plates of chickens with thiram-induced dyschondroplasia.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Antifungal Agents; Apoptosis; Cell Proliferation; C | 2005 |
Induction of tibial dyschondroplasia in turkeys by tetramethylthiuram disulfide (thiram).
Topics: Animals; Body Weight; Chickens; Feeding Behavior; Hindlimb; Lameness, Animal; Mutagens; Osteochondro | 2007 |
Thiram-induced changes in the expression of genes relating to vascularization and tibial dyschondroplasia.
Topics: Animals; Chickens; Down-Regulation; Gene Expression Regulation; Growth Plate; Male; Neovascularizati | 2007 |
Effects of thiuram, disulfiram and a trace element mixture on the incidence of tibial dyschondroplasia in chickens.
Topics: Absorption; Animals; Bone and Bones; Calcium; Calcium Radioisotopes; Chickens; Disulfiram; Half-Life | 1987 |
Influence of dietary tetramethylthiuram disulfide (a fungicide) on growth and incidence of tibial dyschondroplasia in single comb White Leghorn chicks.
Topics: Animals; Bone and Bones; Chickens; Fungicides, Industrial; Male; Osteochondrodysplasias; Poultry Dis | 1986 |
Observations on several factors influencing the incidence of tibial dyschondroplasia in broiler chickens.
Topics: Animals; Chickens; Diet; Lasalocid; Monensin; Osteochondrodysplasias; Potassium; Poultry Diseases; T | 1985 |