Page last updated: 2024-11-05

thiram and Bone Neoplasms

thiram has been researched along with Bone Neoplasms in 1 studies

Thiram: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.
thiram : An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment.

Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.

Research Excerpts

ExcerptRelevanceReference
"The anti-osteosarcoma effects of hydrocortisone and thiram, an inhibitor of type 2 11ß-hydroxysteroid dehydrogenase (11HSD2), have not been reported."8.31Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway. ( Chen, M; Guo, W; Jiang, W; Li, H; Li, N; Zhang, Y, 2023)
"The anti-osteosarcoma effects of hydrocortisone and thiram, an inhibitor of type 2 11ß-hydroxysteroid dehydrogenase (11HSD2), have not been reported."4.31Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway. ( Chen, M; Guo, W; Jiang, W; Li, H; Li, N; Zhang, Y, 2023)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Zhang, Y1
Li, N1
Li, H1
Chen, M1
Jiang, W1
Guo, W1

Other Studies

1 other study available for thiram and Bone Neoplasms

ArticleYear
Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway.
    BMC pharmacology & toxicology, 2023, 03-28, Volume: 24, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Apoptosis; beta Catenin; Bone Neoplasms; Cell

2023