thiourea has been researched along with beta-Thalassemia* in 1 studies
1 other study(ies) available for thiourea and beta-Thalassemia
| Article | Year |
|---|---|
Thiourea derivatives induce fetal hemoglobin production in-vitro: A new class of potential therapeutic agents for β-thalassemia.
Fetal hemoglobin (HbF) induction is a cost-effective therapeutic approach for the treatment of β-hemoglobinopathies like β-thalassemia and sickle cell anemia. The present study discusses the potential of thiourea derivatives as new class of compounds that induce the fetal hemoglobin production. HbF inducing effect of thiourea derivatives was studied using experimental cell system, the human erythroleukemic K562 cell line. Erythroid induction of K562 cells was studied by the benzidine/H Topics: beta-Thalassemia; Cell Differentiation; Cell Proliferation; Cell Survival; Erythroid Cells; Fetal Hemoglobin; Gene Expression Regulation; Humans; K562 Cells; Thiourea | 2019 |