thiourea and Pseudomonas-Infections

thiourea has been researched along with Pseudomonas-Infections* in 1 studies

Other Studies

1 other study(ies) available for thiourea and Pseudomonas-Infections

Article	Year
Thiourea-based spacers in potent divalent inhibitors of Pseudomonas aeruginosa virulence lectin LecA. Organic & biomolecular chemistry, 2015, Nov-28, Volume: 13, Issue:44 A new divalent highly potent inhibitor of the Pseudomonas aeruginosa lectin and virulence factor LecA was prepared. It contains two thiourea linkages which were found to be in the Z,Z isomeric form. This brings the spacer into an elongated conformation required to bridge the two binding sites, which results in the chelating binding mode responsible for the high potency. Topics: Adhesins, Bacterial; Anti-Bacterial Agents; Humans; Lectins; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Thiourea; Virulence Factors	2015

Article

Year

Thiourea-based spacers in potent divalent inhibitors of Pseudomonas aeruginosa virulence lectin LecA.

Organic & biomolecular chemistry, 2015, Nov-28, Volume: 13, Issue:44

A new divalent highly potent inhibitor of the Pseudomonas aeruginosa lectin and virulence factor LecA was prepared. It contains two thiourea linkages which were found to be in the Z,Z isomeric form. This brings the spacer into an elongated conformation required to bridge the two binding sites, which results in the chelating binding mode responsible for the high potency.

Topics: Adhesins, Bacterial; Anti-Bacterial Agents; Humans; Lectins; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Thiourea; Virulence Factors

2015