thiourea has been researched along with Malaria* in 2 studies
2 other study(ies) available for thiourea and Malaria
| Article | Year |
|---|---|
Search for new pharmacophores for antimalarial activity. Part III: synthesis and bioevaluation of new 6-thioureido-4-anilinoquinazolines.
Syntheses and in vitro antimalarial evaluation of 42 new thioureidoquinazolines have been carried out. Several analogs showed promising antimalarial effect in the in vitro investigation against chloroquine-sensitive 3D7 strain of Plasmodium falciparum whereas one of the compounds shows 50% curative effect in the mouse model at an oral dose of 100mg/kg x 4 days against multidrug resistant Plasmodium yoelii nigeriensis. Topics: Animals; Antimalarials; Cell Survival; Chlorocebus aethiops; Female; Malaria; Male; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium yoelii; Quinazolines; Structure-Activity Relationship; Thiourea; Vero Cells | 2009 |
[Criteria for the selection of sulfonamides for the treatment of rodent malaria (Plasmodium vinckei)].
Topics: Animals; Biomechanical Phenomena; Female; Malaria; Male; Mice; Mice, Inbred Strains; Oxazoles; Plasmodium; Pyridines; Pyrimidines; Rodent Diseases; Sulfadimethoxine; Sulfaguanidine; Sulfamethoxazole; Sulfanilamides; Sulfaphenazole; Sulfathiazoles; Sulfonamides; Thiourea; Trimethoprim | 1972 |