thiourea has been researched along with Cystitis* in 3 studies
3 other study(ies) available for thiourea and Cystitis
Article | Year |
---|---|
Inhibitory effect of dimethylthiourea on rat urinary bladder inflammation produced by 6-hydroxydopamine application.
The present study was to investigate 6-hydroxydopamine (6-OHDA)-induced inflammatory response and underlying mechanisms in the urinary bladder in anesthetized male rats of Long-Evans strain. The magnitude of inflammation was evaluated by morphometric analysis of the relative number of leaky blood vessels expressed by the area density of India ink-labeled blood vessels in whole mount specimens. Light and scanning electron microscopies were employed to study the changes in histologic structure and endothelial ultrastructure of bladder wall. Local injection of 6-OHDA to lumen of urinary bladder induced a dose-dependent increase in plasma leakage. Following application of vehicle, 5 mg/kg 6-OHDA, and 10 mg/kg 6-OHDA, area densities of India ink-labeled leaky vessels were 5.65+/-3.72% (N=6), 22.63+/-5.12% (N=6), and 35.02+/-11.25% (N=6), respectively. Inflammatory response was completely abolished by pretreatment alone with dimethylthiourea (DMTU), a hydroxyl radical scavenger, and was also attenuated by pretreatment with L-732,138, a NK1 receptor antagonist. 6-OHDA caused edema formation and venular endothelial gap formation in bladder tissue. It is concluded that 6-OHDA induced inflammation in the rat urinary bladder, the response of which was dose-dependently increased and free radicals and tachykinins were involved in the inflammatory process. Topics: Animals; Capillary Leak Syndrome; Capillary Permeability; Cystitis; Dose-Response Relationship, Drug; Inflammation; Male; Oxidopamine; Rats; Rats, Long-Evans; Thiourea; Urinary Bladder | 2009 |
[Treatment of urinary tract infections in gynecology with Sulfa-Dysural].
Topics: Analgesics; Atropine; Barbiturates; Cystitis; Ephedrine; Female; Humans; Orotic Acid; Parasympatholytics; Pelvic Inflammatory Disease; Pyelitis; Sulfonamides; Thiourea; Urinary Bladder Fistula; Urinary Tract Infections | 1969 |
[Clinical experiences with solu-supronal with special reference to coli infections in cystitis and prostate hypertrophy].
Topics: Cystitis; Drug Combinations; Escherichia coli; Escherichia coli Infections; Humans; Hypertrophy; Male; Prostatic Hyperplasia; Sulfadiazine; Sulfonamides; Thiourea | 1953 |