thiourea and Botulism

thiourea has been researched along with Botulism* in 2 studies

Other Studies

2 other study(ies) available for thiourea and Botulism

Article	Year
[Complex pathogenetic therapy of experimental botulism]. Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:11 The study of survival and life span of mice and white rats upon the administration of LD50 of the toxin has shown that an antihypoxic agent--gutimine (50-200 mg/kg)--had a protecting effect in type C botulinum intoxication. A combined use of gutimine and 4-aminopyridine (1-5 mg/kg), facilitating a transmitter release in synapses, had a more marked protecting effect in botulinum intoxication. Due to the potentiation of the drugs effect during their combined application, the doses of each drug in the combination could be reduced. Topics: 4-Aminopyridine; Aminopyridines; Animals; Botulism; Drug Therapy, Combination; Guanylthiourea; Male; Mice; Thiourea	1987
[Possibilities of pharmacologic correction of Na, K-ATPase activity in the spinal cord in botulism]. Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 100, Issue:10 The experiments on white rats have shown that gutimin is capable of reactivating Na, K-ATPase of the synaptosomes of the jugular spinal cord in type C botulinic intoxication. Serotonin prevented Na, K-ATPase activity inhibition only in preclinical period of intoxication. Parmidin injection did not prevent suppression of Na, K-ATPase activity either in preclinical period or in skeletal muscle paresis. Topics: Animals; Botulism; Ca(2+) Mg(2+)-ATPase; Carbamates; Guanylthiourea; Pyridinolcarbamate; Rats; Serotonin; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Thiourea	1985

Article

Year

[Complex pathogenetic therapy of experimental botulism].

Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:11

The study of survival and life span of mice and white rats upon the administration of LD50 of the toxin has shown that an antihypoxic agent--gutimine (50-200 mg/kg)--had a protecting effect in type C botulinum intoxication. A combined use of gutimine and 4-aminopyridine (1-5 mg/kg), facilitating a transmitter release in synapses, had a more marked protecting effect in botulinum intoxication. Due to the potentiation of the drugs effect during their combined application, the doses of each drug in the combination could be reduced.

Topics: 4-Aminopyridine; Aminopyridines; Animals; Botulism; Drug Therapy, Combination; Guanylthiourea; Male; Mice; Thiourea

1987

[Possibilities of pharmacologic correction of Na, K-ATPase activity in the spinal cord in botulism].

Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 100, Issue:10

The experiments on white rats have shown that gutimin is capable of reactivating Na, K-ATPase of the synaptosomes of the jugular spinal cord in type C botulinic intoxication. Serotonin prevented Na, K-ATPase activity inhibition only in preclinical period of intoxication. Parmidin injection did not prevent suppression of Na, K-ATPase activity either in preclinical period or in skeletal muscle paresis.

Topics: Animals; Botulism; Ca(2+) Mg(2+)-ATPase; Carbamates; Guanylthiourea; Pyridinolcarbamate; Rats; Serotonin; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Thiourea

1985