thiouracil has been researched along with Goiter* in 130 studies
2 review(s) available for thiouracil and Goiter
Article | Year |
---|---|
[Struma medicamentosa--a survey].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Animals; Antimony; Barbiturates; Child; Child, Preschool; Cobalt; Depression, Chemical; Diazepam; Female; Goiter; Guinea Pigs; Humans; Hydantoins; Hypoglycemic Agents; Hypothyroidism; Infant, Newborn; Iodine; Lithium; Male; Perchlorates; Phenothiazines; Phenylbutazone; Pregnancy; Sulfonamides; Thiocyanates; Thiouracil; Thyroid Function Tests; Thyroid Gland; Xanthines | 1971 |
THE USE OF THIOURACIL DERIVATIVES DURING PREGNANCY: A REVIEW.
Topics: Basal Metabolism; Female; Fetal Death; Goiter; Humans; Hyperthyroidism; Infant; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methylthiouracil; Pregnancy; Pregnancy Complications; Propylthiouracil; Research; Thiouracil; Thyroid Function Tests; Thyrotropin; Thyroxine; Toxicology | 1964 |
1 trial(s) available for thiouracil and Goiter
Article | Year |
---|---|
Long-term outcome of hyperthyroidism treated with antithyroid drugs.
Topics: Adult; Antithyroid Agents; Clinical Trials as Topic; Female; Follow-Up Studies; Goiter; Humans; Hyperthyroidism; Male; Middle Aged; Prognosis; Propylthiouracil; Thiouracil | 1966 |
127 other study(ies) available for thiouracil and Goiter
Article | Year |
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Upregulation of the angiogenic factors PlGF, VEGF and their receptors (Flt-1, Flk-1/KDR) by TSH in cultured thyrocytes and in the thyroid gland of thiouracil-fed rats suggest a TSH-dependent paracrine mechanism for goiter hypervascularization.
Placenta growth factor (PlGF) and vascular endothelial growth factor (VEGF) represent two closely related angiogenic growth factors active as homodimers or heterodimers. Since goiters of the thyroid gland are extremely hypervascular, we investigated the expression of PlGF, VEGF and their receptors, Flt-1 and Flk-1/KDR, in a small panel of human goiters from patients with Graves's disease, in an animal model of thyroid goitrogenesis and in in vitro cultured thyroid cells. Here we report that the mRNA expression of PlGF, VEGF and their receptors is markedly enhanced in biopsies of goiters resected from Graves's patients. In vivo studies demonstrated that in the thyroid gland of thiouracil-fed rats, increased mRNA and protein expression of PIGF, VEGF, Flt-1 and Flk-1/KDR occurred subsequent to the rise in the serum thyroid stimulating hormone (TSH) levels and in parallel with thyroid capillary proliferation. In vitro studies confirmed the existence of such TSH-dependent paracrine communication between thyroid epithelial cells and endothelium since the conditioned medium collected from TSH-stimulated thyrocytes acquired mitogenic activity for human umbilical vein endothelial (HUVE) cells. Altogether, these data suggest that PlGF and VEGF, released by thyrocytes in response to the chronic activation of the TSH receptor pathway, may act through a paracrine mechanism on thyroid endothelium. Topics: Animals; Antithyroid Agents; Cells, Cultured; Culture Media, Conditioned; Endothelial Growth Factors; Endothelium, Vascular; Goiter; Graves Disease; Humans; Lymphokines; Neovascularization, Pathologic; Placenta Growth Factor; Pregnancy Proteins; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Rats; Rats, Inbred Strains; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Thiouracil; Thyroid Gland; Thyrotropin; Umbilical Veins; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 1997 |
Expression of the endothelin-1 gene in the rat thyroid gland and changes in its peptide and mRNA levels in goiter formation and iodide-induced involution.
Endothelin-1 (ET-1) is a major vasoconstrictor peptide, first found in endothelial cells, and later in many other tissues, including the thyroid gland. We analysed the expression of the ET-1 gene in the rat thyroid gland and changes in ET-1 mRNA and peptide levels in goiter development and involution, two circumstances characterised by vascular changes. Thyroid hyperplasia was induced in adult Wistar rats by feeding a low iodine diet (LID) supplemented with 0.25% thiouracil for 10 days, and LID alone for 2 further days (H.12 group). Involution was induced by injecting 100 micrograms iodide and refeeding a normal diet during 6 h, 12 h, and 24 h (I.6h, I.12h, I.24h groups). Rats fed a normal iodine diet were used as controls. A specific 488 bp cDNA corresponding to the known sequence of pre-pro ET-1 was found by RT-PCR from RNA extracts in all thyroid experimental groups, as well as in lung and kidney which were used as positive controls. RP-HPLC analysis showed that ET-1 immunoreactivity eluted similarly as mature ET-1. During hyperplasia, ET-1 mRNA and peptide levels were increased 3.5- and 5-fold respectively. The relative volume of the vascular bed was more than doubled. During iodide-induced involution, the glandular ET-1 mRNA level remained elevated. The concentration of ET-1 peptide increased and was significantly greater at 12 h involution than in the H.12 group. At this time, the capillary reticulum reverted to individual capillaries and the vascular bed was significantly reduced. These data demonstrate that the ET-1 gene is expressed in the rat thyroid gland and that the ET-1 mRNA and peptide levels are increased during thyroid hyperplasia and remain elevated during a phase of rapid iodide-induced involution. These data suggest that changes in ET-1 production may play a role in control of thyroid gland trophic regulation and vascularity. Topics: Animals; Base Sequence; Chromatography, High Pressure Liquid; Diet; Endothelins; Gene Expression; Goiter; Iodine; Male; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Thiouracil; Thyroid Gland | 1994 |
Structural changes in the thyroid gland of buffalo following administration of thiouracil.
The effects of a goitrogen (thiouracil) on the structural variations of the thyroid gland were studied in male buffalo calves. Following the treatment, the thyroid became enlarged and both the weight and the size of the gland were significantly increased (P less than 0.01). Hyperplasia and hypertrophy of the gland were correlated with a significant increase of thyroidal uptake of 131I. The height and number of the follicular cells were significantly increased (P less than 0.01). The follicles were small and had vacuolations in the colloid. The colloid content of the follicles became reduced. The vascularity of the gland was appreciably increased. Topics: Animal Feed; Animals; Buffaloes; Goiter; Hypertrophy; Male; Organ Size; Thiouracil; Thyroid Gland | 1978 |
[Thyroid gland hormones--thyreostatic drugs].
Topics: Antithyroid Agents; Chemistry; Contraceptives, Oral; Female; Goiter; History, 19th Century; History, 20th Century; Humans; Hyperthyroidism; Hypothyroidism; Imidazoles; Iodine Radioisotopes; Lithium; Perchlorates; Pregnancy; Thiouracil; Thyroid (USP); Thyroid Diseases; Thyroid Hormones; Thyroid Neoplasms; Thyroxine; Triiodothyronine | 1974 |
Studies of positive iodine compounds as models of the thyroidal "active iodine": reaction of N-iodosuccinimide and of N-iodophtalimide with thiocarbamide goitrogens.
Topics: Azides; Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Goiter; Heterocyclic Compounds; Imides; Iodine; Kinetics; Models, Biological; Nitrogen; Phthalic Acids; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Succinimides; Thiouracil; Thiourea; Thyroid Gland; Time Factors | 1974 |
Role of thyroidal lysosomes in the hydrolysis of thyroglobulin and its relation to the development of iodide goiter.
Topics: Acid Phosphatase; Animals; Cathepsins; Centrifugation, Density Gradient; Glucuronidase; Goiter; Hydrogen-Ion Concentration; Hydrolysis; Iodides; Iodine Radioisotopes; Lysosomes; Male; Polyethylene Glycols; Rats; Thiouracil; Thyroglobulin; Thyroid Gland; Thyrotropin; Thyroxine | 1974 |
Thyroxine analogs. 22. Thyromimetic activity of halogen-free derivatives of 3,5-dimethyl-L-thyronine.
Topics: Animals; Dose-Response Relationship, Drug; Goiter; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Rats; Structure-Activity Relationship; Thiouracil; Thyronines; Thyroxine | 1974 |
Hypervitaminosis E in the chick.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Bone and Bones; Calcification, Physiologic; Calcium; Chickens; Deficiency Diseases; Erythropoiesis; Goiter; Hypothyroidism; Iodine; Iodine Radioisotopes; Male; Mitochondria, Muscle; Oxygen Consumption; Thiouracil; Thyroid Gland; Vitamin D Deficiency; Vitamin E | 1973 |
Thyromimetric activity of 3,5,3'-trimethyl-L-thyronine.
Topics: Animals; Chromatography, Thin Layer; Goiter; Mass Spectrometry; Methylation; Optical Rotation; Rats; Thiouracil; Thyronines | 1973 |
The management of thyroid diseases.
Topics: Adolescent; Adult; Age Factors; Antithyroid Agents; Carbimazole; Child; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Iodine Isotopes; Propranolol; Thiouracil; Thyroid Diseases; Thyroxine; Triiodothyronine | 1972 |
Effect of thyroidectomy and of several goitrogens on -glucuronidase activity and insulin levels of rats.
Topics: Animals; Chlorates; Diet; Glucuronidase; Goiter; Insulin; Iodine; Male; Rats; Thiocyanates; Thiouracil; Thyroid Gland; Thyroid Hormones; Thyroidectomy | 1972 |
Studies on goitrogenic action of minocycline and related compounds.
Topics: Animals; Autoradiography; Blood Proteins; Chromatography; Chromatography, Paper; Diet; Female; Goiter; Iodine; Iodine Isotopes; Male; Methylamines; Organ Size; Pituitary Gland; Protein Binding; Rats; Tetracycline; Thiouracil; Thyroid Gland; Thyroidectomy; Thyroxine; Triiodothyronine | 1972 |
Electrophoretic mobility and isoelectric point of hog thyroglobulin.
Topics: Animals; Chromatography, DEAE-Cellulose; Electrophoresis; Goiter; Hydrogen-Ion Concentration; Iodine; Isoelectric Focusing; Swine; Thiouracil; Thyroglobulin; Thyroid Gland; Ultracentrifugation; Urea | 1972 |
Thyroid storm shortly after 131 I therapy of a toxic multinodular goiter?
Topics: Aged; Arthritis, Rheumatoid; Autopsy; Diabetes Complications; Female; Goiter; Goiter, Nodular; Heart Failure; Humans; Hyperthyroidism; Iodine Isotopes; Thiouracil; Thyroid Crisis; Thyroid Gland | 1972 |
Thyroidal changes in the rat during acclimation to simulated high altitude.
Topics: Acclimatization; Altitude; Animals; Female; Goiter; Hyperthyroidism; Hypothyroidism; Iodine; Rats; Rats, Inbred Strains; Thiouracil; Thyroid Function Tests; Thyroid Gland; Thyroidectomy; Thyrotropin; Thyroxine | 1971 |
[Effect of phosphorylcholine and dextran sulfate on the goitrogenic action of propylthiouracil (author's transl)].
Topics: Animals; Choline; Dextrans; Drug Evaluation; Goiter; Male; Organ Size; Propylthiouracil; Rats; Thiouracil; Thyroid Gland | 1971 |
Potency of United States Pharmacopeia dessicated thyroid tablets as determined by the antigoitrogenic assay in rats.
Topics: Animals; Biological Assay; Diet; Female; Goiter; Iodine; Organ Size; Pharmacopoeias as Topic; Rats; Tablets; Thiouracil; Thyroid Hormones; United States | 1970 |
[Recent works on simple goiter in Spain].
Topics: Child; Goiter; Goiter, Endemic; Humans; Iodine; Spain; Thiouracil; Thyroxine | 1969 |
The ligature of the inferior thyroid artery and the incidence of goitre recurrence after subtotal thyroidectomy.
Topics: Animals; Arteries; Chronic Disease; Goiter; Guinea Pigs; Humans; Thiouracil; Thyroid Gland; Thyroidectomy; Thyrotropin | 1969 |
Functional alterations in rat thyroid ribosomes.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Goiter; Male; Phenylalanine; Polynucleotides; Protein Biosynthesis; Proteins; Rats; Ribosomes; RNA, Messenger; Thiouracil; Thyroid Gland; Thyrotropin; Uracil Nucleotides | 1969 |
[Goiter therapy in childhood and adolescence].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Deficiency Diseases; Disease Reservoirs; Female; Goiter; Humans; Hyperthyroidism; Imidazoles; Iodine; Male; Sex Factors; Thiouracil; Thyroid Function Tests; Thyroid Gland; Thyroid Hormones; Thyroxine; Tissue Extracts; Triiodothyronine | 1968 |
Ultrastructural observations on the droplets of experimentally-induced goitres in Xenopus laevis with especial reference to the development of Uhlenhuth colloid cells.
Topics: Animals; Anura; Colloids; Goiter; Microscopy, Electron; Perchlorates; Thiocyanates; Thiouracil; Thiourea | 1968 |
[Fetal poisonings and endocrine complications].
Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Congenital Hypothyroidism; Cushing Syndrome; Female; Glucocorticoids; Goiter; Humans; Hydrocortisone; Hyperparathyroidism; Hyperthyroidism; Hypocalcemia; Hypoparathyroidism; Infant, Newborn; Iodine; Maternal-Fetal Exchange; Parathyroid Diseases; Pregnancy; Thiouracil; Thyroid Hormones | 1968 |
[Analysis of thyroid iodoproteins by polyacrylamide gel electrophoresis].
Topics: Acrylic Resins; Animals; Autoradiography; Carbon Isotopes; Electrophoresis, Disc; Gels; Goiter; Humans; Hypothyroidism; Immune Sera; Immunodiffusion; Iodine; Iodine Isotopes; Iodoproteins; Methods; Proteins; Rats; Thiouracil; Thyroglobulin; Thyroid Hormones; Tissue Extracts | 1968 |
Thyromimetics. VII. Isopropyl analogs of thyroid hormones.
Topics: Animals; Chemistry, Organic; Goiter; Organic Chemistry Phenomena; Rats; Thiouracil; Thyroid Hormones | 1967 |
[Goiters induced or aggravated by ill chosen prescription of synthetic antithyroids].
Topics: Adolescent; Adult; Antithyroid Agents; Blood Cell Count; Diagnosis, Differential; Diagnostic Errors; Female; Goiter; Heart Auscultation; Humans; Hyperthyroidism; Iodine Radioisotopes; Male; Methylthiouracil; Myxedema; Nervous System Diseases; Neurotic Disorders; Propylthiouracil; Radioisotope Dilution Technique; Thiazoles; Thiouracil; Thiourea; Thyrotropin | 1967 |
[Goiter induced or aggravated by the untimely prescription of synthetic antithyroid agents].
Topics: Adolescent; Adult; Aged; Antithyroid Agents; Basal Metabolism; Chromatography; Female; Goiter; Humans; Hypothyroidism; Iodine Isotopes; Male; Middle Aged; Radionuclide Imaging; Thiouracil; Thyroid Function Tests | 1967 |
Two different types of goitrogen blockage: their importance in the neural control of the thyroid gland.
Topics: Animals; Body Weight; Brain; Ear, Middle; Goiter; Hypertrophy; Hypothalamus; Male; Methods; Organ Size; Rats; Thiouracil; Thyroid Gland; Thyrotropin | 1967 |
Iodide goiter in the mouse.
Topics: Animals; Body Weight; DNA; Goiter; Hypophysectomy; Iodides; Iodine; Iodine Isotopes; Male; Mice; Organ Size; Pituitary Gland; Proteins; RNA; Thiouracil; Thyroid Gland; Thyroid Hormones; Thyrotropin; Trichloroacetic Acid | 1967 |
Goitrogenic activity of cassava (a staple Nigerian food).
Topics: Animals; Diet; Female; Goiter; Iodine Isotopes; Manihot; Nigeria; Rats; Thiouracil; Thyroid Function Tests; Thyroid Gland | 1966 |
NUCLEIC ACID SYNTHESIS IN NORMAL AND GOITROUS RAT THYROID.
Topics: Antithyroid Agents; Carbon Isotopes; Chromatography; Cytosine Nucleotides; DNA; Glucosyltransferases; Goiter; Metabolism; Orotic Acid; Pharmacology; Phosphotransferases; Rats; Research; RNA; Spectrophotometry; Thiouracil; Thyroid Gland; Uracil; Uracil Nucleotides | 1965 |
Physiological considerations in the management of thyroid cancer.
Topics: 17-Ketosteroids; Adolescent; Adult; Animals; Estradiol; Estrogens; Female; Follow-Up Studies; Goiter; Humans; Iodine Isotopes; Male; Metabolism, Inborn Errors; Mice; Neoplasm Metastasis; Pituitary Neoplasms; Radiography, Thoracic; Rats; Thiouracil; Thyroid Neoplasms; Thyrotropin; Thyroxine; Triiodothyronine | 1965 |
DIAGNOSTIC PATTERNS. LESIONS OF THE THYROID GLAND.
Topics: Antithyroid Agents; Chlorides; Cobalt; Goiter; Graves Disease; Humans; Microscopy; Pathology; Thiouracil; Thyroid Diseases; Thyroid Neoplasms; Thyroiditis; Thyroiditis, Autoimmune; Toxicology | 1964 |
THE EFFECTS OF VARIOUS GOITROGENS ON THE DETERMINATION OF THE RELATIVE POTENCY OF THYROID BY THE GOITRE PREVENTION ASSAY.
Topics: Anti-Infective Agents, Local; Antithyroid Agents; Basal Metabolism; Diet; Goiter; Humans; Iodides; Iodine; Perchlorates; Pharmacology; Thiocyanates; Thiouracil; Thyroid Gland; Thyroxine; Triiodothyronine | 1964 |
FEMALE GENITAL CARCINOMA AND THYROID DISEASE.
Topics: Carcinoma; Endometriosis; Endometritis; Female; Goiter; Graves Disease; Humans; Hyperthyroidism; Iodine Isotopes; Myxedema; Neoplasms; Ovarian Neoplasms; Salpingitis; Thiouracil; Thyroid Diseases; Thyroidectomy; Tuberculosis; Tuberculosis, Female Genital; Uterine Cervical Neoplasms; Uterine Neoplasms | 1964 |
[STUDY OF THE SOLUBLE PROTEINS OF THE THYROID GLAND OF PATIENTS TREATED WITH IODO-IODATED SOLUTION AND WITH THIOURACIL DRUGS].
Topics: Autoradiography; Electrophoresis; Goiter; Humans; Hyperthyroidism; Iodates; Iodides; Iodine; Iodine Isotopes; Methylthiouracil; Proteins; Thiouracil; Thyroglobulin; Thyroid Gland | 1964 |
[TREATMENT OF HYPERTHYROIDISM].
Topics: Aging; Antithyroid Agents; Exophthalmos; Goiter; Humans; Hyperthyroidism; Iodides; Iodine; Iodine Isotopes; Postoperative Complications; Thiocyanates; Thiouracil; Thyroidectomy | 1964 |
FURTHER OBSERVATIONS ON THYROIDITIS AND COLLOID ACCUMULATION IN HYPERPLASTIC THYROID GLANDS OF HAMSTERS RECEIVING EXCESS IODINE.
Topics: Animals; Colloids; Cortisone; Cricetinae; Goiter; Hyperplasia; Hyperthyroidism; Iodine; Pharmacology; Research; Sulfadiazine; Thiocyanates; Thiouracil; Thyroiditis; Triiodothyronine | 1964 |
COMPARISON OF ESTIMATES FOR THYROXINE SECRETION RATE DETERMINED BY THE GOITER PREVENTION ASSAY AND BY MEASURING THE ACTIVITY OF SERUM ALKALINE PHOSPHATASE IN THE CHICKEN.
Topics: Alkaline Phosphatase; Animals; Biological Assay; Biomedical Research; Chickens; Goiter; Meat; Pharmacology; Physiology; Poultry; Research; Thiouracil; Thyroid Gland; Thyroxine | 1964 |
Adrenergic blockade and thyrotoxicosis.
Topics: Adrenergic Agents; Exophthalmos; Goiter; Graves Disease; Guanethidine; Humans; Thiouracil; Thyrotoxicosis | 1963 |
THE BIOASSAY OF THYROACTIVE MATERIALS BY THE MOUSE ANOXIA TEST AND GOITRE-PREVENTION RESPONSE IN THE SAME EXPERIMENTAL ANIMALS.
Topics: Animals; Biological Assay; Goiter; Hypoxia; Mice; Pharmacology; Research; Thiouracil; Thyroid Function Tests; Thyroid Hormones | 1963 |
[MODERN THERAPY OF HYPERTHYROIDISM].
Topics: Antithyroid Agents; Exophthalmos; Goiter; Graves Disease; Humans; Hyperthyroidism; Iodine Isotopes; Methylthiouracil; Perchlorates; Radiotherapy; Thiouracil; Thiourea; Thyroidectomy | 1963 |
Studies on the production of high radioiodine uptake goiter with propylthiouracil.
Topics: Goiter; Iodides; Iodine; Iodine Radioisotopes; Propylthiouracil; Thiouracil | 1962 |
Goitrogenic action of thyroxine administered with propylthiouracil.
Topics: Goiter; Propylthiouracil; Thiouracil; Thyroxine | 1962 |
[Isotopes in diagnosis and treatment of endocrine exophthalmos].
Topics: Exophthalmos; Goiter; Graves Disease; Graves Ophthalmopathy; Humans; Hyaluronoglucosaminidase; Iodine Isotopes; Prednisone; Thiouracil; Thyrotropin | 1962 |
Role of iodine, sodium chloride and antithyroid drugs in the development of goiter in the rat.
Topics: Animals; Antithyroid Agents; Goiter; Iodides; Iodine; Rats; Sodium Chloride; Thiouracil | 1962 |
Interference with deiodination of some thyroxine analogues in the rat.
Topics: Animals; Goiter; Iodides; Iodine; Rats; Thiouracil; Thyroxine; Triiodothyronine | 1961 |
[Combined treatment with methylthiouracil and radioactive iodine (I-131) of patients with toxic goiter].
Topics: Combined Modality Therapy; Goiter; Hyperthyroidism; Iodine; Iodine Radioisotopes; Methylthiouracil; Thiouracil; Thyrotoxicosis | 1960 |
The effect of reserpine on goitre induced by thiouracil.
Topics: Goiter; Reserpine; Thiouracil | 1960 |
[Endocrinological questions on the pathogenesis of goiter recurrence].
Topics: Goiter; Humans; Pituitary Gland; Pituitary Gland, Anterior; Thiouracil | 1960 |
The effects of hypothalamic lesions on goitrogenesis and pituitary TSH secretion in the propylthiouracil-treated guinea pig.
Topics: Goiter; Guinea Pigs; Hypothalamus; Pituitary Gland; Propylthiouracil; Thiouracil; Thyrotropin | 1959 |
Observations on the production of goiter in rats with propylthiouracil and on goiter prevention.
Topics: Animals; Biomedical Research; Goiter; Iodides; Iodine; Propylthiouracil; Rats; Thiouracil | 1959 |
[Maternal nutrition in pathogenesis of neonatal goiter].
Topics: Child; Female; Goiter; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Maternal Nutritional Physiological Phenomena; Nutritional Physiological Phenomena; Pregnancy; Prenatal Nutritional Physiological Phenomena; Thiouracil; Vegetables | 1959 |
Experimental colloid goitre produced by thiouracil.
Topics: Colloids; Goiter; Thiouracil | 1959 |
[Prevention of thiouracil effect and iodine deficiency goiter by experimental destruction of the nuclei habenulae].
Topics: Diencephalon; Goiter; Goiter, Endemic; Humans; Iodine; Thiouracil; Thyroid Diseases | 1958 |
[Influence of prednisolone on propylthiouracil-induced goiter].
Topics: Goiter; Leadership; Prednisolone; Propylthiouracil; Thiouracil | 1958 |
Qualitative differences in the physiologic activity of thyroxine and its formic acid analogue.
Topics: Cholesterol; Formates; Goiter; Lipid Metabolism; Liver; Thiouracil; Thyrotropin; Thyroxine | 1957 |
Goiters in twins resulting from propylthiouracil given during pregnancy.
Topics: Child; Disease; Diseases in Twins; Female; Goiter; Humans; Hyperthyroidism; Infant; Pregnancy; Propylthiouracil; Thiouracil; Twins | 1957 |
Thyroid disorders in the newborn.
Topics: Child; Female; Goiter; Humans; Hyperthyroidism; Infant; Infant, Newborn; Infant, Newborn, Diseases; Pregnancy; Thiouracil; Thyroid Diseases | 1957 |
[Thiouracil goiter; thyroid size in patients with Graves and Basedow's syndrome treated with methylthiouracil].
Topics: Goiter; Humans; Hyperthyroidism; Methylthiouracil; Syndrome; Thiouracil | 1957 |
Hyperactivity of hypothalamic neurosecretion and coincidental occurrence of thyroid enlargement following administration of methylthiouracil.
Topics: Goiter; Hyperkinesis; Hyperthyroidism; Hypothalamus; Methylthiouracil; Neurosecretion; Pharmaceutical Preparations; Thiouracil | 1957 |
Enhancement of goitrogenic action of propylthiouracil by thyroxin.
Topics: Goiter; Propylthiouracil; Thiouracil; Thyroxine | 1957 |
On the inhibitory effect of 3:5-dinitro-1-thyronine on the development of goitre in guinea-pigs treated with methylthiouracil.
Topics: Goiter; Guinea Pigs; Methylthiouracil; Thiouracil; Thyronines; Thyroxine | 1956 |
Goitrogenic action of prophyl-thiouracil.
Topics: Goiter; Thiouracil | 1956 |
The influence of estrogen upon goiter induction in adult and immature rats.
Topics: Animals; Estradiol; Estrogens; Goiter; Hyperthyroidism; Rats; Thiouracil | 1956 |
[Repression of cholinergic depot substances in reactive thyroid gland follicular hyperplasia in female rats].
Topics: Acetylcholine; Animals; Cholinergic Agents; Cholinesterase Inhibitors; Female; Goiter; Hyperplasia; Neoplasms; Neostigmine; Pregnancy; Pregnancy Complications; Rats; Thiouracil; Thyroid Gland; Thyroid Neoplasms | 1956 |
Goiter in newborn infant due to mother's ingestion of propylthiouracil.
Topics: Child; Eating; Goiter; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Mothers; Propylthiouracil; Thiouracil | 1955 |
Thyroid function in infant with congenital goiter resulting from exposure to propylthiouracil.
Topics: Child; Goiter; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Propylthiouracil; Thiouracil | 1955 |
Iodothiouracil in treatment of toxic goitre.
Topics: Goiter; Hyperthyroidism; Thiouracil; Thyrotoxicosis | 1954 |
[Effect of ACTH on goiter produced by propylthiouracil].
Topics: Adrenocorticotropic Hormone; Goiter; Propylthiouracil; Thiouracil | 1954 |
[Effect of butazolidine on goiter produced by propylthiouracil in rat].
Topics: Analgesics; Animals; Goiter; Propylthiouracil; Rats; Thiouracil | 1954 |
[The antagonistic effect of iodine compounds and methylthiouracil with special reference to the inhibition of thiouracil-induced goiter].
Topics: Goiter; Iodides; Iodine; Iodine Compounds; Methylthiouracil; Musculoskeletal Physiological Phenomena; Thiouracil; Thyroxine | 1954 |
[The effect of BAL, methionine and cystine on thyroid hyperplasia after short administration of methylthiouracil].
Topics: Cystine; Dimercaprol; Goiter; Hyperplasia; Hypertrophy; Methionine; Methylthiouracil; Pharmaceutical Preparations; Thiouracil; Thyroid Gland; Viscera | 1954 |
[Effect of BAL, methionine and cystine on thyroid hyperplasia after short methylthiouracil administration].
Topics: Cystine; Dimercaprol; Goiter; Hyperplasia; Hypertrophy; Methionine; Methylthiouracil; Thiouracil | 1954 |
Thiouracil goitre in a newborn.
Topics: Child; Female; Goiter; Humans; Hyperthyroidism; Infant; Infant, Newborn; Pregnancy; Thiouracil | 1954 |
The treatment of thyrotoxicosis.
Topics: Goiter; Humans; Hyperthyroidism; Iodine; Iodine Radioisotopes; Myxedema; Thiouracil; Thyroid Gland; Thyrotoxicosis | 1953 |
[ACTH in goiter following thiouracil therapy].
Topics: Adrenocorticotropic Hormone; Goiter; Humans; Thiouracil | 1953 |
[Vitamin E and methylthiouracil goiter].
Topics: Goiter; Methylthiouracil; Thiouracil; Vitamin E | 1953 |
Late results with propylthiouracil treatment of hyperthyroidism in a goiter region.
Topics: Goiter; Hyperthyroidism; Propylthiouracil; Thiouracil | 1953 |
[Effects of sex hormones on thiouracil goiter].
Topics: Estrogens; Goiter; Gonadal Steroid Hormones; Humans; Progesterone; Thiouracil | 1953 |
Thiouracil in toxic goitre; late results in a personal series.
Topics: Goiter; Hyperthyroidism; Thiouracil; Thyrotoxicosis | 1952 |
[The question of malignant degeneration of the thyroid gland treated with methyl thiouracil].
Topics: Antithyroid Agents; Goiter; Humans; Thiouracil | 1952 |
Some observations on the treatment and preoperative treatment of toxic goitre with thiuracil.
Topics: Goiter; Hyperthyroidism; Thiouracil; Thyrotoxicosis | 1952 |
Congenital thyroid hyperplasia in twins; report of a case following administration of thiouracil and iodine to mother during pregnancy.
Topics: Disease; Female; Goiter; Humans; Hyperplasia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Iodides; Iodine; Mothers; Pregnancy; Thiouracil; Thyroid Diseases; Thyroid Gland | 1952 |
The goiter problem today.
Topics: Goiter; Hyperthyroidism; Thiouracil | 1951 |
Fatal agranulocytosis during treatment of toxic goiter with propylthiouracil.
Topics: Agranulocytosis; Goiter; Graves Disease; Humans; Propylthiouracil; Thiouracil; Thyrotoxicosis | 1951 |
[Preoperative therapy of hyperthyroid goiter with thyreostatic drugs and Plummer solution].
Topics: Goiter; Graves Disease; Humans; Hyperthyroidism; Iodine; Iodine Isotopes; Neoadjuvant Therapy; Thiouracil | 1951 |
Factors contributing to the difference in propylthiouracil goitrogenesis in rats and guinea pigs.
Topics: Animals; Goiter; Guinea Pigs; Propylthiouracil; Rats; Thiouracil | 1951 |
[Blood vitamin K in goiter and its relation to the administration of thiouracil].
Topics: Antifibrinolytic Agents; Goiter; Hyperthyroidism; Naphthoquinones; Thiouracil; Vitamin K | 1951 |
Observations on the prolonged medical management of toxic diffuse goiter with thiouracil and propylthiouracil.
Topics: Disease Management; Goiter; Graves Disease; Propylthiouracil; Thiouracil | 1950 |
A genetic response to induced goiter in chickens.
Topics: Animals; Chickens; Genetics; Goiter; Meat; Thiouracil | 1950 |
Diseases of the thyroid.
Topics: Goiter; Graves Disease; Humans; Iodides; Iodine; Iodine Radioisotopes; Thiouracil; Thyroid Gland | 1950 |
Ambulatory preparation for thyroidectomy.
Topics: Exophthalmos; Goiter; Graves Disease; Humans; Thiouracil; Thyroid Gland; Thyroidectomy | 1950 |
Exophthalmos and hyperthyroidism; some views on a case of thyrotrophic exophthalmos with hyperthyroidism liver damage and anemia after 8 years.
Topics: Anemia; Estrogens; Exophthalmos; Goiter; Graves Disease; Humans; Hyperthyroidism; Liver; Thiouracil; Thyroid Gland | 1950 |
[More logic in the prescription of thiouracil preparations].
Topics: Goiter; Logic; Thiouracil; Thyroid Gland | 1950 |
[Effects of methylthiouracil and aminothiazole in preoperative therapy in Basedow's disease and thyreotoxicosis].
Topics: Goiter; Graves Disease; Humans; Methylthiouracil; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiouracil; Thyroid Gland | 1950 |
[Recurrent goiter and thiouracil; local and vicarious relapse].
Topics: Chronic Disease; Goiter; Graves Disease; Recurrence; Thiouracil | 1950 |
[Electrocardiography in Basedow disease: ECG reports before and after treatment with thiouracil derivatives].
Topics: Electrocardiography; Exophthalmos; Goiter; Graves Disease; Humans; Thiouracil; Thiourea | 1949 |
Substernal goiter and pulmonary emphysema.
Pulmonary emphysema is not an infrequent complication of tracheal compression due to goiter. In many cases the goiter is in the mediastinum and therefore overlooked. Among 13 patients with this combination of disease, chronic cough, dyspnea and wheezing were the chief respiratory symptoms. Ten of the 13 patients also had hyperthyroidism; in eight of the ten the disease was of the "masked" variety and both the thyrotoxicosis and the mediastinal mass were overlooked. Early recognition and surgical removal of substernal goiter may prevent or retard otherwise irreversible and progressive tracheobronchopulmonary disease. Medical management of such cases with thiouracil preparations may lessen the toxic symptoms but probably will not affect the mechanical compression of the trachea. Topics: Cough; Dyspnea; Emphysema; Goiter; Goiter, Substernal; Humans; Hyperthyroidism; Mediastinum; Pulmonary Emphysema; Respiratory Sounds; Thiouracil; Thyrotoxicosis | 1949 |
Action of iodine on goiters previously treated with thiouracil.
Topics: Goiter; Goiter, Endemic; Iodides; Iodine; Thiouracil; Thiourea | 1949 |
Effect of various compounds containing iodine and other halogens on thiouracil goitre.
Topics: Goiter; Halogens; Iodides; Iodine; Iodine Isotopes; Thiouracil; Thiourea | 1948 |
Thiouracil and its derivatives in the treatment of Graves' disease.
Topics: Exophthalmos; Goiter; Graves Disease; Thiouracil; Thiourea | 1948 |
Continuous treatment with methyl thiouracil in thyrotoxic goiter.
Topics: Endocrine System Diseases; Goiter; Musculoskeletal Diseases; Thiouracil; Thiourea; Thyroid Gland | 1948 |
Propylthiouracil in Graves' disease.
Topics: Goiter; Graves Disease; Graves Ophthalmopathy; Humans; Propylthiouracil; Thiouracil | 1948 |
Thiouracil in toxic goitre.
Topics: Goiter; Thiouracil; Thiourea; Thyrotoxicosis | 1948 |
Further observations on thiouracil and related substances in the treatment of toxic goiter.
Topics: Exophthalmos; Goiter; Graves Disease; Thiouracil; Thiourea; Thyrotoxicosis | 1948 |
Thiouracil in toxic goitre.
Topics: Goiter; Humans; Thiouracil; Thyrotoxicosis | 1948 |
Thiouracil in toxic goitre.
Topics: Goiter; Humans; Thiouracil; Thyrotoxicosis | 1947 |
Esophageal hiatus hernia.
Topics: Goiter; Graves Disease; Thiouracil | 1947 |
Propylthiouracil in the treatment of toxic goiter.
Topics: Goiter; Graves Disease; Propylthiouracil; Thiouracil; Thyrotoxicosis | 1947 |
Thiouracil in toxic goitre: a review of four years' experience.
Topics: Goiter; Humans; Hyperthyroidism; Thiouracil; Thyrotoxicosis | 1947 |
Thiouracil; preoperative use in 400 patients with severe hyperthyroidism.
Topics: Exophthalmos; Goiter; Graves Disease; Humans; Hyperthyroidism; Thiouracil | 1947 |
The status of thiouracil in the treatment of toxic goiter.
Topics: Goiter; Humans; Hyperthyroidism; Thiouracil; Thyroid Gland; Thyrotoxicosis | 1947 |
Relation between Graves' disease and liver pathology; importance in the use of thiouracil.
Topics: Goiter; Graves Disease; Hyperthyroidism; Liver; Thiouracil; Thyroid Gland | 1947 |
Thyroidectomy and thiouracil in toxic goitre; an interim comparison.
Topics: Goiter; Graves Disease; Humans; Hyperthyroidism; Thiouracil; Thyroid Gland; Thyroidectomy; Thyrotoxicosis | 1947 |
Thiouracil in the treatment of toxic goiter, and its dangers.
Topics: Goiter; Goiter, Nodular; Graves Disease; Humans; Hyperthyroidism; Thiouracil; Thyroid Gland; Thyrotoxicosis | 1947 |
Treatment of Basedowi's disease and hyperthyroidism with thioÅ «racilderivaten.
Topics: Exophthalmos; Goiter; Graves Disease; Thiouracil | 1946 |
What has thiouracil contributed to the management of Graves' disease.
Topics: Exophthalmos; Goiter; Graves Disease; Hyperthyroidism; Thiouracil; Thyroid Gland | 1946 |
Treatment of Mb. Basedowi with thiomidil 'Wander' (4-methylthiouracil-2-thio-4-methyl-6-oxypyrimidine); three cases.
Topics: Exophthalmos; Goiter; Graves Disease; Hyperthyroidism; Thiouracil; Thyroid Gland | 1946 |
THIOURACIL in the management of Graves' disease.
Topics: Exophthalmos; Goiter; Graves Disease; Humans; Hypertrophy; Thiouracil; Thyroid Gland | 1946 |
Remissions in thyrotoxicosis after discontinuing thiouracil.
Topics: Goiter; Hypertrophy; Neoplasms; Thiouracil; Thyroid Gland; Thyrotoxicosis | 1946 |
Preliminary report on the use of thiouracil in thyrotoxicosis.
Topics: Goiter; Hypertrophy; Thiouracil; Thyroid Gland; Thyrotoxicosis | 1946 |
Thiouracil in the treatment of Graves' disease.
Topics: Exophthalmos; Goiter; Graves Disease; Thiouracil | 1946 |
Thiourea and its derivative thiouracil as a goitrogen.
Topics: Antithyroid Agents; Goiter; Thiouracil; Thiourea | 1946 |
Pharmacology and therapeutic aspects of goiter; thiourea and thiouracil.
Topics: Goiter; Humans; Hyperthyroidism; Thiouracil; Thiourea; Thyroid Gland | 1946 |
Antithyroid substances; on the thyroid hyperplasia following the administration of methylthiouracil and some related compounds.
Topics: Goiter; Hyperplasia; Methylthiouracil; Pharmaceutical Preparations; Thiouracil; Thiourea; Thyroid Gland | 1945 |
The goitrogenic and toxic effects upon the albino rat of three pyrimidine-containing compounds chemically related to thiouracil.
Topics: Animals; Goiter; Pyrimidines; Rats; Thiouracil | 1945 |