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thiothixene and Psychotic Disorders

thiothixene has been researched along with Psychotic Disorders in 31 studies

Thiothixene: A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"We studied the incidence of akathisia in two populations of newly admitted schizophrenic patients: one group was treated with haloperidol and the other group was treated with thiothixene hydrochloride."2.65Akathisia with haloperidol and thiothixene. ( Marder, SR; May, PR; Van Putten, T, 1984)
", as needed over a four-hour period (total dosage ranging from 4 to 32 mg."2.64Relative efficacy of parenteral haloperidol and thiothixene for the emergency treatment of acutely excited and agitated patients. ( Stotsky, BA, 1977)
"In fact, Reyes developed neuroleptic malignant syndrome (NMS) as a direct result of the antipsychotic medications she was administered."1.29Neuroleptic malignant syndrome: liability in nursing practice. ( Blair, DT; Dauner, A, 1993)
" By taking into account these potential sources of pharmacokinetic variability when monitoring plasma thiothixene concentrations, more appropriate dosing of thiothixene may be achieved."1.28Thiothixene pharmacokinetic interactions: a study of hepatic enzyme inducers, clearance inhibitors, and demographic variables. ( Davis, CM; Ereshefsky, L; Jann, MW; Saklad, SR; Watanabe, MD, 1991)
"Valproic acid is infrequently used for treatment of psychosis."1.28Neuroleptic-valproic acid combination in treatment of psychotic symptoms: a three-case report. ( Bryant, S; Flack, J; Morrison, P; Wassef, A; Watson, DJ, 1989)
" In the antipsychotic classification, special attention is given to side effects (extrapyramidal motor signs, tardive dyskinesias, akathisis) and to dosage for the elderly."1.25Observations on the psychopharmacology of the aged. ( Eisdorfer, C, 1975)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199027 (87.10)18.7374
1990's3 (9.68)18.2507
2000's0 (0.00)29.6817
2010's1 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Veronin, MA1
Colson, K1
Roffman, ME1
Roman, MW1
Howard, JS1
Kucharski, LT1
Alexander, P1
Tune, L1
Coyle, J1
Van Putten, T1
May, PR1
Marder, SR1
Soria, ME1
de Silva, FP1
Carr, SL1
Polonowita, A1
Goode, DJ1
Manning, AA1
Middleton, JF1
Williams, B1
Yesavage, JA1
Becker, J1
Werner, PD1
Mills, MJ1
Holman, CA1
Cohn, R1
Blair, DT1
Dauner, A1
Woodring, JH1
Martin, CA1
Keefer, B1
Ketai, R1
Mason, AS1
Granacher, RP1
Eisdorfer, C1
Ban, TA1
Lehmann, HE1
Sterlin, C1
Climan, M1
Stotsky, BA1
Simeon, J3
Itil, TM3
Swett, C1
Ereshefsky, L1
Saklad, SR1
Watanabe, MD1
Davis, CM1
Jann, MW1
Wassef, A1
Watson, DJ1
Morrison, P1
Bryant, S1
Flack, J1
Garza-TreviƱo, ES1
Hollister, LE2
Overall, JE1
Alexander, WF1
Dubin, WR2
Waxman, HM1
Weiss, KJ2
Ramchandani, D1
Tavani-Petrone, C1
Joseph, AB1
Bowers, MB1
Swigar, ME1
Yassa, R1
Mohelsky, HE1
Pelonero, AL1
Levenson, JL1
Silverman, JJ1
Saletu, B2
Saletu, M2
DaSilva, J2
Schiele, BC1
Gallant, D1
Simpson, G1
Gardner, EA1
Cole, JO2
Orlov, P1
Kasparian, G1
DiMascio, A1

Trials

9 trials available for thiothixene and Psychotic Disorders

ArticleYear
Haloperidol for chronically hospitalized psychotics: a double-blind comparison with thiothixene and placebo; a follow-up open evaluation.
    Diseases of the nervous system, 1974, Volume: 35, Issue:10

    Topics: Adult; Aged; Antipsychotic Agents; Attitude of Health Personnel; Double-Blind Method; Female; Follow

1974
Akathisia with haloperidol and thiothixene.
    Archives of general psychiatry, 1984, Volume: 41, Issue:11

    Topics: Adult; Akathisia, Drug-Induced; Anxiety Disorders; Depressive Disorder; Dose-Response Relationship,

1984
Comprehesiven clinical studies with thiothixene.
    Diseases of the nervous system, 1975, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Aged; Chlorpromazine; Clinical Trials as Topic; Clopenthixol; Drug Evaluation; Fe

1975
Relative efficacy of parenteral haloperidol and thiothixene for the emergency treatment of acutely excited and agitated patients.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12

    Topics: Acute Disease; Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation

1977
Efficacy of combinations of intramuscular antipsychotics and sedative-hypnotics for control of psychotic agitation.
    The American journal of psychiatry, 1989, Volume: 146, Issue:12

    Topics: Adolescent; Adult; Drug Combinations; Drug Therapy, Combination; Female; Haloperidol; Humans; Inject

1989
Rapid tranquilization: the efficacy of oral concentrate.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:11

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Drug Administrat

1985
Rapid tranquilization: a comparison of thiothixene with loxapine.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Bipolar Disorder; Dibenzoxazepines; Double-Blind Meth

1986
Thiothixene in childhood psychoses.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Alpha Rhythm; Autistic Disorder; Body Weight; Child Behavior Disorders; Clinical Trials as Topic; Co

1974
Behavioral and visual evoked potential investigations during trihexyphenidyl and thiothixene treatment in psychotic boys.
    Biological psychiatry, 1974, Volume: 8, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Electroencephalograp

1974

Other Studies

22 other studies available for thiothixene and Psychotic Disorders

ArticleYear
Full circle-old drugs prove more beneficial than newer agents for schizophrenia: a case report.
    Issues in mental health nursing, 2012, Volume: 33, Issue:11

    Topics: Antipsychotic Agents; Benztropine; Bipolar Disorder; Borderline Personality Disorder; Drug Substitut

2012
Serum neuroleptic concentrations and clinical response: a radioreceptor assay investigation of acutely psychotic patients.
    Psychopharmacology, 1984, Volume: 82, Issue:3

    Topics: Adolescent; Adult; Antipsychotic Agents; Benztropine; Female; Fluphenazine; Haloperidol; Humans; Mal

1984
The intramuscular use of thiothixene in severely disturbed and agitated patients.
    Rhode Island medical journal, 1984, Volume: 67, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Humans; Injections, Intramuscular; Male; Middle Aged; Psychomotor

1984
Intramuscular thiothixene in acute psychotic states.
    The New Zealand medical journal, 1980, Dec-24, Volume: 92, Issue:674

    Topics: Adolescent; Adult; Aged; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Psychotic Dis

1980
Fine motor performance before and after treatment in schizophrenic and schizoaffective patients.
    Psychiatry research, 1981, Volume: 5, Issue:3

    Topics: Adult; Female; Humans; Loxapine; Male; Molindone; Motor Skills; Psychotic Disorders; Schizophrenia;

1981
Serum level monitoring of thiothixene in schizophrenia: acute single-dose levels at fixed doses.
    The American journal of psychiatry, 1982, Volume: 139, Issue:2

    Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Psychiatri

1982
Neuroleptic malignant syndrome: liability in nursing practice.
    Journal of psychosocial nursing and mental health services, 1993, Volume: 31, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain Damage, Chronic; Dose-Response Relationship, Drug; Female; Halope

1993
Esophageal atony and dilatation as a side effect of thiothixene and benztropine.
    Hospital & community psychiatry, 1993, Volume: 44, Issue:7

    Topics: Benztropine; Colonic Pseudo-Obstruction; Drug Therapy, Combination; Esophageal Achalasia; Esophageal

1993
High-dosage and versatile drug therapy with treatment-resistant psychotic patients.
    Hospital & community psychiatry, 1976, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Doxepin; Female; Hospitals, Psychiatric; Hu

1976
Basic principles of rapid neuroleptization.
    Diseases of the nervous system, 1976, Volume: 37, Issue:10

    Topics: Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Fluphenazine; Ha

1976
Observations on the psychopharmacology of the aged.
    Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:2

    Topics: Aged; Amantadine; Antidepressive Agents; Antipsychotic Agents; Basal Ganglia Diseases; Butyrophenone

1975
Computerized Electroencephalogram. A model of understanding the brain function in childhood psychosis and its treatment.
    Journal of autism and childhood schizophrenia, 1975, Volume: 5, Issue:3

    Topics: Acoustic Stimulation; Adolescent; Autistic Disorder; Brain; Child; Child, Preschool; Diagnosis, Comp

1975
Drug-induced dystonia.
    The American journal of psychiatry, 1975, Volume: 132, Issue:5

    Topics: Adjustment Disorders; Adult; Basal Ganglia Diseases; Chlorpromazine; Chlorprothixene; Female; Fluphe

1975
Thiothixene pharmacokinetic interactions: a study of hepatic enzyme inducers, clearance inhibitors, and demographic variables.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:5

    Topics: Administration, Oral; Adult; Drug Interactions; Enzyme Induction; Female; Humans; Intellectual Disab

1991
Neuroleptic-valproic acid combination in treatment of psychotic symptoms: a three-case report.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:1

    Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Female; Hallucinations; Humans; Male; Middle

1989
Delusional misidentification of the Capgras and intermetamorphosis types responding to clorazepate. A case report.
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:3

    Topics: Anti-Anxiety Agents; Capgras Syndrome; Clorazepate Dipotassium; Drug Therapy, Combination; Female; H

1987
Psychotic patients who become worse on neuroleptics.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Antipsychotic Agents; Benztropine; Chlorpromazine; Dyskinesia, Drug-Induced; Fema

1988
Tardive dyskinesia in thiothixene treatment.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:4

    Topics: Aged; Dyskinesia, Drug-Induced; Female; Humans; Psychotic Disorders; Thiothixene

1985
Neuroleptic therapy following neuroleptic malignant syndrome.
    Psychosomatics, 1985, Volume: 26, Issue:12

    Topics: Adult; Drug Therapy, Combination; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome; Perphen

1985
Tardive dyskinesia. A persistent neurological syndrome associated with antipsychotic drug use.
    Annals of internal medicine, 1973, Volume: 79, Issue:1

    Topics: Age Factors; Butyrophenones; Chlorprothixene; Face; Female; Humans; Male; Mandible; Mouth; Movement

1973
Withdrawal of antiparkinson drugs.
    Archives of general psychiatry, 1971, Volume: 25, Issue:5

    Topics: Biperiden; Butyrophenones; Female; Humans; Male; Parasympatholytics; Parkinson Disease; Psychotic Di

1971
Choice of antipsychotic drugs.
    The American journal of psychiatry, 1970, Volume: 127, Issue:2

    Topics: Butyrophenones; Drug Synergism; Drug Tolerance; Haloperidol; Humans; Phenothiazines; Piperazines; Pi

1970