thiothixene has been researched along with Neuroleptic Malignant Syndrome in 5 studies
Thiothixene: A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In fact, Reyes developed neuroleptic malignant syndrome (NMS) as a direct result of the antipsychotic medications she was administered." | 1.29 | Neuroleptic malignant syndrome: liability in nursing practice. ( Blair, DT; Dauner, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blair, DT | 1 |
| Dauner, A | 1 |
| Petzinger, GM | 1 |
| Bressman, SB | 1 |
| Waggoner, PC | 1 |
| Hansen, R | 1 |
| Pelonero, AL | 1 |
| Levenson, JL | 1 |
| Silverman, JJ | 1 |
5 other studies available for thiothixene and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic malignant syndrome: liability in nursing practice.
Topics: Adult; Antipsychotic Agents; Brain Damage, Chronic; Dose-Response Relationship, Drug; Female; Halope | 1993 |
A case of tetrabenazine-induced neuroleptic malignant syndrome after prolonged treatment.
Topics: Adult; Anti-Dyskinesia Agents; Depressive Disorder; Dyskinesia, Drug-Induced; Female; Humans; Neurol | 1997 |
Case study: neuroleptic malignant syndrome.
Topics: Aged; Aged, 80 and over; Critical Care; Female; Humans; Neuroleptic Malignant Syndrome; Thiothixene | 1992 |
Combative patient with fever and altered mental status.
Topics: Adult; Bipolar Disorder; Emergencies; Fever of Unknown Origin; Humans; Male; Neuroleptic Malignant S | 1986 |
Neuroleptic therapy following neuroleptic malignant syndrome.
Topics: Adult; Drug Therapy, Combination; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome; Perphen | 1985 |