thiothixene has been researched along with Chronic Illness in 35 studies
Thiothixene: A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The case described is of a woman who developed marked leg edema during thiothixene administration, and other cases of neuroleptic induced edema are reviewed." | 7.67 | Thiothixene induced edema. ( Gift, TE; Scuderi, S, 1986) |
| "Glycine was administered in an effort to facilitate endogenous glutamatergic transmission at the level of the N-methyl-D-aspartate (NMDA) receptor complex, since a glutamatergic deficiency in the pathophysiology of schizophrenia has been postulated." | 5.28 | Glycine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label, pilot study. ( Banay-Schwartz, M; Cohen, CG; Deutsch, SI; Leighton, M; Rosse, RB; Scarcella, E; Theut, SK, 1989) |
| "The case described is of a woman who developed marked leg edema during thiothixene administration, and other cases of neuroleptic induced edema are reviewed." | 3.67 | Thiothixene induced edema. ( Gift, TE; Scuderi, S, 1986) |
| "Positron emission tomography (PET) with 11C-2-deoxyglucose (11DG) was used to compare regional brain metabolism in four patients with chronic schizophrenia who had no history of psychotropic medication and in 12 normal controls." | 3.67 | Brain metabolism in patients with schizophrenia before and after acute neuroleptic administration. ( Angrist, B; Brodie, JD; Cancro, R; Russell, J; Volkow, ND; Wolf, AP, 1986) |
| " For penfluridol, a significant correlation between dosage and plasma level and also between dosage and changes in psychopathology as regards factor 5 in the Märtens & Jonsson S scale which comprises the items most characteristic of a schizophrenic syndrome, was found." | 2.64 | Penfluridol and thiothixene. Dosage, plasma levels and changes in psychopathology. ( Edenius, B; Jacobsson, L; Kettner, B; Magnusson, KE; Mattsson, B; Mjörndal, T; Oreland, L; Perris, C; Rapp, W; Villemoes, P; von Knorring, L, 1976) |
| "Glycine was administered in an effort to facilitate endogenous glutamatergic transmission at the level of the N-methyl-D-aspartate (NMDA) receptor complex, since a glutamatergic deficiency in the pathophysiology of schizophrenia has been postulated." | 1.28 | Glycine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label, pilot study. ( Banay-Schwartz, M; Cohen, CG; Deutsch, SI; Leighton, M; Rosse, RB; Scarcella, E; Theut, SK, 1989) |
| "Penfluridol has the clear practical advantage of being the only long-acting drug for oral administration so far available." | 1.26 | Controlled trial of penfluridol and thiothixene in the maintenance treatment of chronic schizophrenic syndromes. ( Edenius, B; Jacobsson, L; Kettner, B; Magnusson, KE; Mattsson, B; Perris, C; Rapp, W; Villemoes, P; Von Knorring, L, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (82.86) | 18.7374 |
| 1990's | 6 (17.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gardos, G | 2 |
| Orzack, MH | 1 |
| Finn, G | 1 |
| Cole, JO | 1 |
| Brodie, JD | 4 |
| Christman, DR | 1 |
| Corona, JF | 1 |
| Fowler, JS | 1 |
| Gomez-Mont, F | 2 |
| Jaeger, J | 2 |
| Micheels, PA | 1 |
| Rotrosen, J | 2 |
| Russell, JA | 1 |
| Volkow, ND | 2 |
| Kim, DY | 1 |
| Hollister, LE | 2 |
| Schneider, SJ | 1 |
| Slotnick, VB | 1 |
| Bergman, A | 1 |
| O'Brien, J | 1 |
| Osgood, G | 1 |
| Cornblatt, B | 1 |
| Miller, DD | 1 |
| Rezai, K | 1 |
| Alliger, R | 1 |
| Andreasen, NC | 1 |
| Engelhardt, DM | 1 |
| Rudorfer, L | 1 |
| Rosen, B | 1 |
| Jacobsson, L | 2 |
| von Knorring, L | 2 |
| Mattsson, B | 2 |
| Mjörndal, T | 1 |
| Oreland, L | 1 |
| Perris, C | 2 |
| Rapp, W | 2 |
| Edenius, B | 2 |
| Kettner, B | 2 |
| Magnusson, KE | 2 |
| Villemoes, P | 2 |
| Vianna Filho, U | 1 |
| Versiani Caldeira, V | 1 |
| Romildo Bueno, J | 1 |
| Zakowska-Dabrowska, T | 1 |
| Szczepańska, W | 1 |
| Itil, TM | 4 |
| Marasa, J | 1 |
| Saletu, B | 1 |
| Davis, S | 1 |
| Mucciardi, AN | 1 |
| Burnett, GB | 1 |
| Little, SR | 1 |
| Graham, N | 1 |
| Forrest, AD | 1 |
| Ruiz-Navarro, JF | 1 |
| Vergara, L | 1 |
| Deutsch, M | 1 |
| Serban, G | 1 |
| Siegel, S | 1 |
| Gaffney, M | 1 |
| Bartlett, EJ | 1 |
| Wolkin, A | 2 |
| Laska, EM | 1 |
| Wolf, AP | 3 |
| Sanfilipo, M | 1 |
| Costa, J | 1 |
| Khaled, E | 1 |
| Sramek, J | 1 |
| Bunney, W | 1 |
| Potkin, SG | 1 |
| Lindenmayer, JP | 1 |
| Vakharia, M | 1 |
| Kanofsky, D | 1 |
| Rosse, RB | 1 |
| Theut, SK | 1 |
| Banay-Schwartz, M | 1 |
| Leighton, M | 1 |
| Scarcella, E | 1 |
| Cohen, CG | 1 |
| Deutsch, SI | 1 |
| Lombrozo, L | 1 |
| Huang, CC | 1 |
| Scuderi, S | 1 |
| Gift, TE | 1 |
| Angrist, B | 1 |
| Russell, J | 1 |
| Cancro, R | 2 |
| Fowler, J | 1 |
| Holden, JM | 3 |
| Hsu, W | 1 |
| Keskiner, A | 3 |
| Hobbs, DC | 1 |
| Welch, WM | 1 |
| Short, MJ | 1 |
| Moody, WA | 1 |
| Van der Velde, CD | 1 |
| Dillenkoffer, RL | 1 |
| George, RB | 1 |
| Bishop, MP | 1 |
| Gallant, DM | 1 |
| Patterson, CD | 1 |
| Sterlin, C | 2 |
| Ban, TA | 2 |
| Jarrold, L | 1 |
| Saarma, J | 1 |
| Saarma, M | 1 |
| Sild, L | 1 |
| Tikk, P | 1 |
| Oliveros, RT | 1 |
| Lehmann, HE | 1 |
| Saxena, BM | 1 |
| Kellam, AM | 1 |
| Jones, KS | 1 |
| Gannon, PJ | 1 |
| Simpson, GM | 1 |
| Amin, M | 1 |
| Angus, JW | 1 |
| Edwards, JG | 1 |
| Go, SH | 1 |
| Lee, JH | 1 |
16 trials available for thiothixene and Chronic Illness
| Article | Year |
|---|---|
High and low dose thiothixene treatment in chronic schizophrenia.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Attention; Chronic Disease; Cognition; Dose-Respo | 1974 |
Haloperidol and thiothixene in the long-term treatment of chronic schizophrenic outpatients in an urban community: social and vocational adjustment.
Topics: Adolescent; Adult; Ambulatory Care; Chronic Disease; Double-Blind Method; Drug Evaluation; Employmen | 1978 |
Penfluridol and thiothixene. Dosage, plasma levels and changes in psychopathology.
Topics: Adult; Chromatography, Gas; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, D | 1976 |
The efficacy and safety of loxapine succinate in the treatment of schizophrenia: a comparative study with thiothixene.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as To | 1975 |
Computerized EEG: predictor of outcome in schizophrenia.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Computers; Drug Resistance; Electroencephalography | 1975 |
The assessment of thiothixene in chronic schizophrenia. A double-blind controlled trial.
Topics: Adult; Chemical Phenomena; Chemistry; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Hu | 1975 |
Proceedings: A comparative study of thiothixene and chlorpromazine in chronic schizophrenic patients: application of a special psychometric test battery.
Topics: Adult; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; | 1976 |
Plasma concentrations of thiothixene and clinical response in treatment-resistant schizophrenics.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Met | 1987 |
Electrocardiographic evaluation of thiothixene: a double-blind comparison with thioridazine.
Topics: Chronic Disease; Clinical Trials as Topic; Electrocardiography; Female; Heart Rate; Humans; Hypotens | 1974 |
Comparison of phenothiazine and nonphenothiazine neuroleptics according to psychopathology, side effects and computerized EEG.
Topics: Alpha Rhythm; Chronic Disease; Clinical Trials as Topic; Computers; Electroencephalography; Female; | 1974 |
Are antipsychotic drugs interchangeable?
Topics: Attitude; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, | 1974 |
The place of thiothixene among the thioxanthenes.
Topics: Acute Disease; Adolescent; Adult; Central Nervous System; Chlorprothixene; Chronic Disease; Clinical | 1972 |
Thiothixene. Its range of therapeutic activity.
Topics: Acute Disease; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Depression; Female; Humans; M | 1970 |
A double blind controlled trial of thiothixene and perphenazine in chronic schizophrenics shown to require maintenance therapy.
Topics: Age Factors; Chronic Disease; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Hospita | 1971 |
The clinical effects of intramuscular thiothixene and trifluoperazine in chronic schizophrenia: a comparative study.
Topics: Adult; Chronic Disease; Electroencephalography; Female; Humans; Injections, Intramuscular; Male; Mid | 1971 |
Role of antidepressants and neuroleptics in the treatment of depression.
Topics: Adult; Amitriptyline; Chronic Disease; Depression; Female; Humans; Imipramine; Male; Middle Aged; Pi | 1972 |
19 other studies available for thiothixene and Chronic Illness
| Article | Year |
|---|---|
Patterns of metabolic activity in the treatment of schizophrenia.
Topics: Adult; Brain; Chronic Disease; Glucose; Humans; Male; Middle Aged; Schizophrenia; Thiothixene; Tissu | 1984 |
Drug-refractory chronic schizophrenics: doses and plasma concentrations of thiothixene.
Topics: Adult; Chronic Disease; Humans; Male; Schizophrenia; Thiothixene | 1984 |
Electrodermal activity and therapeutic response to neuroleptic treatment in chronic schizophrenic in-patients.
Topics: Aged; Chronic Disease; Female; Galvanic Skin Response; Humans; Male; Middle Aged; Psychiatric Status | 1982 |
Haloperidol and thiothixene in the long-term treatment of chronic schizophrenic outpatients in an urban community: social and vocational adjustment.
Topics: Adult; Ambulatory Care; Chronic Disease; Employment; Female; Haloperidol; Humans; Male; Middle Aged; | 1980 |
Distractibility in schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Attention; Chronic Disease; Cognition Disord | 1995 |
The effect of antipsychotic medication on relative cerebral blood perfusion in schizophrenia: assessment with technetium-99m hexamethyl-propyleneamine oxime single photon emission computed tomography.
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Brain; Brain Mapping; Cerebellum; Cerebral Cortex; Chron | 1997 |
[Dynamics of schizophrenic apathetic psychosyndrome treated with Navane].
Topics: Chronic Disease; Female; Hallucinations; Humans; Male; Schizophrenia; Schizophrenia, Paranoid; Socia | 1975 |
Controlled trial of penfluridol and thiothixene in the maintenance treatment of chronic schizophrenic syndromes.
Topics: Adolescent; Adult; Aged; Biperiden; Chlorpromazine; Chronic Disease; Drug Evaluation; Female; Humans | 1976 |
Response of negative symptoms of schizophrenia to neuroleptic treatment.
Topics: Adult; Ambulatory Care; Chronic Disease; Female; Humans; Male; Middle Aged; Psychiatric Status Ratin | 1992 |
Importance of pharmacologic control in PET studies: effects of thiothixene and haloperidol on cerebral glucose utilization in chronic schizophrenia.
Topics: Adult; Basal Ganglia; Blood Glucose; Brain; Brain Mapping; Chronic Disease; Dose-Response Relationsh | 1991 |
An open trial of glycine as an adjunct to neuroleptics in chronic treatment-refractory schizophrenics.
Topics: Adult; Chronic Disease; Drug Therapy, Combination; Fluphenazine; Glycine; Humans; Male; Psychiatric | 1990 |
Fluoxetine in chronic schizophrenia.
Topics: Amantadine; Chronic Disease; Drug Therapy, Combination; Fluoxetine; Humans; Loxapine; Male; Middle A | 1990 |
Glycine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label, pilot study.
Topics: Adjuvants, Pharmaceutic; Adult; Aged; Basal Ganglia Diseases; Benztropine; Chronic Disease; Cognitio | 1989 |
Thiothixene induced edema.
Topics: Chronic Disease; Edema; Female; Humans; Middle Aged; Schizophrenia; Thiothixene | 1986 |
Brain metabolism in patients with schizophrenia before and after acute neuroleptic administration.
Topics: Adult; Basal Ganglia; Brain; Cerebral Cortex; Chronic Disease; Deoxyglucose; Glucose; Humans; Male; | 1986 |
Persistence of cerebral metabolic abnormalities in chronic schizophrenia as determined by positron emission tomography.
Topics: Adult; Basal Ganglia; Brain; Chronic Disease; Deoxyglucose; Fluorine; Fluorodeoxyglucose F18; Fronta | 1985 |
Predictor patterns in the management of therapy-resistant schizophrenia.
Topics: Adult; Age Factors; Chronic Disease; Disability Evaluation; Female; Fluphenazine; Hospitalization; H | 1971 |
Pharmacokinetics of thiothixene in man.
Topics: Administration, Oral; Adult; Chromatography, Gas; Chronic Disease; Deuterium; Female; Humans; Isotop | 1974 |
Effect of thiothixene upon the higher nervous activity in chronic schizophrenics.
Topics: Adult; Blood Pressure; Chronic Disease; Female; Galvanic Skin Response; Heart Rate; Higher Nervous A | 1974 |