thiotepa has been researched along with Wilms Tumor in 10 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These cases demonstrate that it is feasible and safe to perform HSCT in pediatric patients with low nGFR using melphalan- and thiotepa-based preparative therapy." | 2.72 | Autologous hematopoietic stem cell transplant with melphalan and thiotepa is safe and feasible in pediatric patients with low normalized glomerular filtration rate. ( Gross, TG; Grovas, A; Klopfenstein, K; Rosselet, R; Termuhlen, AM, 2006) |
| "The tumors included 18 neuroblastomas, 5 soft tissue sarcomas, 2 hepatoblastomas, and 1 Wilms tumor." | 1.42 | Perioperative management after high-dose chemotherapy with autologous or allogeneic hematopoietic stem cell transplantation for pediatric solid tumors. ( Hashii, Y; Miyamura, T; Nakahata, K; Nara, K; Oue, T; Owari, M; Uehara, S; Ueno, T; Usui, N, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uehara, S | 1 |
| Oue, T | 1 |
| Nakahata, K | 1 |
| Nara, K | 1 |
| Ueno, T | 1 |
| Owari, M | 1 |
| Usui, N | 1 |
| Miyamura, T | 1 |
| Hashii, Y | 1 |
| Kremens, B | 1 |
| Gruhn, B | 1 |
| Klingebiel, T | 1 |
| Hasan, C | 1 |
| Laws, HJ | 1 |
| Koscielniak, E | 1 |
| Hero, B | 1 |
| Selle, B | 1 |
| Niemeyer, C | 1 |
| Finckenstein, FG | 1 |
| Schulz, A | 1 |
| Wawer, A | 1 |
| Zintl, F | 1 |
| Graf, N | 1 |
| RAVINA, A | 1 |
| Campbell, AD | 1 |
| Cohn, SL | 1 |
| Reynolds, M | 1 |
| Seshadri, R | 1 |
| Morgan, E | 1 |
| Geissler, G | 1 |
| Rademaker, A | 1 |
| Marymount, M | 1 |
| Kalapurakal, J | 1 |
| Haut, PR | 1 |
| Duerst, R | 1 |
| Kletzel, M | 1 |
| Termuhlen, AM | 1 |
| Grovas, A | 1 |
| Klopfenstein, K | 1 |
| Rosselet, R | 1 |
| Gross, TG | 1 |
| Izhogin, DG | 1 |
| Boiarshinov, VK | 1 |
| Dolgonolov, IS | 1 |
| Iankelevich, MIa | 1 |
| Ptushkina, EA | 1 |
| Mentkevich, GL | 1 |
| Horn, TD | 1 |
| Beveridge, RA | 1 |
| Egorin, MJ | 1 |
| Abeloff, MD | 1 |
| Hood, AF | 1 |
| Kenis, Y | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
| Britell, JC | 1 |
| Olson, KB | 1 |
| Horton, J | 1 |
| Baxter, D | 1 |
1 review available for thiotepa and Wilms Tumor
| Article | Year |
|---|---|
Chemotherapy of residual disease in solid tumours.
Topics: Colonic Neoplasms; Cyclophosphamide; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Lun | 1971 |
2 trials available for thiotepa and Wilms Tumor
| Article | Year |
|---|---|
Autologous hematopoietic stem cell transplant with melphalan and thiotepa is safe and feasible in pediatric patients with low normalized glomerular filtration rate.
Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Combined Modality Therapy; Drug Therapy, Combin | 2006 |
[High-dose thiotepa chemotherapy in children].
Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child | 2000 |
7 other studies available for thiotepa and Wilms Tumor
| Article | Year |
|---|---|
Perioperative management after high-dose chemotherapy with autologous or allogeneic hematopoietic stem cell transplantation for pediatric solid tumors.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj | 2015 |
High-dose chemotherapy with autologous stem cell rescue in children with nephroblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Combined Modal | 2002 |
[THE PRACTITIONER AND ANTINEOPLASTIC CHEMOTHERAPY. RECENT DATA].
Topics: Antineoplastic Agents; Dactinomycin; Glioma; Hodgkin Disease; Leukemia; Leukemia, Myeloid; Perfusion | 1965 |
Treatment of relapsed Wilms' tumor with high-dose therapy and autologous hematopoietic stem-cell rescue: the experience at Children's Memorial Hospital.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cy | 2004 |
Observations and proposed mechanism of N,N',N''-triethylenethiophosphoramide (thiotepa)-induced hyperpigmentation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; | 1989 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |
Wilms' tumor. Effect of chemotherapy on survival.
Topics: Child; Child, Preschool; Dactinomycin; Female; Fluorouracil; Humans; Infant; Male; Nitrogen Mustard | 1972 |