thiotepa has been researched along with Vitreoretinopathy, Proliferative in 1 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Vitreoretinopathy, Proliferative: Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kon, CH | 1 |
| Occleston, NL | 1 |
| Foss, A | 1 |
| Sheridan, C | 1 |
| Aylward, GW | 1 |
| Khaw, PT | 1 |
1 other study available for thiotepa and Vitreoretinopathy, Proliferative
| Article | Year |
|---|---|
Effects of single, short-term exposures of human retinal pigment epithelial cells to thiotepa or 5-fluorouracil: implications for the treatment of proliferative vitreoretinopathy.
Topics: Alkylating Agents; Antimetabolites; Cell Culture Techniques; Cell Division; Cell Survival; Collagen; | 1998 |