thiotepa has been researched along with Testicular Neoplasms in 11 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study analyzes the clinical and bacteriologic features of CSF infections that occurred in patients with neoplastic meningitis treated with thiotepa and methotrexate administered through a subcutaneous reservoir and ventricular catheter (SRVC)." | 3.66 | CSF infections complicating the management of neoplastic meningitis. Clinical features and results of therapy. ( Grossman, SA; Murray, K; Thompson, G; Trump, DL, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ekhart, C | 1 |
| Rodenhuis, S | 1 |
| Beijnen, JH | 1 |
| Huitema, AD | 1 |
| Minichmayr, I | 1 |
| Nock, V | 1 |
| Jaehde, U | 1 |
| Kloft, C | 1 |
| Tanji, S | 1 |
| Obara, W | 1 |
| Sugimura, J | 1 |
| Ohmori, S | 1 |
| Matsushita, Y | 1 |
| Tokunaga, H | 1 |
| Konda, R | 1 |
| Fujioka, T | 1 |
| Murai, K | 1 |
| Ishida, Y | 1 |
| Trump, DL | 1 |
| Grossman, SA | 1 |
| Thompson, G | 1 |
| Murray, K | 1 |
| Rick, O | 2 |
| Siegert, W | 2 |
| Beyer, J | 2 |
| Bokemeyer, C | 1 |
| Hartmann, JT | 1 |
| Schwella, N | 1 |
| Kingreen, D | 1 |
| Neureither, S | 1 |
| Metzner, B | 1 |
| Casper, J | 1 |
| Wandt, H | 1 |
| Hartmann, F | 1 |
| Schmoll, HJ | 1 |
| Derigs, G | 1 |
| Gerl, A | 1 |
| Berdel, WE | 1 |
| Kanz, L | 1 |
| Carter, SK | 1 |
| Wasserman, TH | 1 |
| Morin, LJ | 1 |
| Loening, S | 1 |
| Livingston, RB | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
| Goldenson, Y | 1 |
| Lev, L | 1 |
| Robinson, E | 1 |
2 reviews available for thiotepa and Testicular Neoplasms
| Article | Year |
|---|---|
Chemotherapy of solid tumors. Recent advances.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinom | 1976 |
[Combination chemotherapy in the treatment of cancer].
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Dacti | 1972 |
1 trial available for thiotepa and Testicular Neoplasms
| Article | Year |
|---|---|
Salvage treatment with paclitaxel, ifosfamide, and cisplatin plus high-dose carboplatin, etoposide, and thiotepa followed by autologous stem-cell rescue in patients with relapsed or refractory germ cell cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-Free S | 2001 |
8 other studies available for thiotepa and Testicular Neoplasms
| Article | Year |
|---|---|
Pharmacokinetics of cyclophosphamide and thiotepa in a conventional fractionated high-dose regimen compared with a novel simplified unfractionated regimen.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biotransformation | 2009 |
Thrombocytopenia following high-dose chemotherapy with carboplatin, etoposide and thiotepa in patients with testicular germ cell cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Etoposide; Humans; Male; Neoplas | 2013 |
[Refractory germ cell cancer of testis treated by salvage high-dose chemotherapy: report of three cases].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin | 2004 |
CSF infections complicating the management of neoplastic meningitis. Clinical features and results of therapy.
Topics: Adult; Breast Neoplasms; Catheters, Indwelling; Cerebral Ventricles; Cerebrospinal Fluid; Female; Hu | 1982 |
High-dose salvage chemotherapy. Germ-cell tumor treatment results in Germany.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Clinical T | 1999 |
The chemotherapy of urologic cancer.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Co | 1975 |
Malignant androblastoma (Sertoli cell tumor) of the testis. A case report with a review of the literature.
Topics: Cyclophosphamide; Dactinomycin; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pleu | 1975 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |