thiotepa has been researched along with Soft Tissue Neoplasms in 5 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with metastatic breast cancer (MBC), early dose intensification with multiple cycles of peripheral blood stem cell-supported high-dose chemotherapy (HDCT) seems superior to a late dose-intensification strategy." | 1.31 | Comparison of double and triple high-dose chemotherapy with autologous blood stem cell transplantation in patients with metastatic breast cancer. ( Bastert, G; Egerer, G; Goerner, R; Grischke, EM; Haas, R; Hensel, M; Ho, AD; Hohaus, S; Khbeis, T; Schneeweiss, A; Solomayer, E, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klingebiel, T | 1 |
| Boos, J | 1 |
| Beske, F | 1 |
| Hallmen, E | 1 |
| Int-Veen, C | 1 |
| Dantonello, T | 1 |
| Treuner, J | 1 |
| Gadner, H | 1 |
| Marky, I | 1 |
| Kazanowska, B | 1 |
| Koscielniak, E | 1 |
| Yonemoto, T | 1 |
| Tatezaki, S | 1 |
| Ishii, T | 1 |
| Satoh, T | 1 |
| Bashey, A | 1 |
| Corringham, S | 1 |
| Garrett, J | 1 |
| Lane, TA | 1 |
| Gilpin, EA | 1 |
| Corringham, RE | 1 |
| Law, P | 1 |
| Ho, AD | 2 |
| Schneeweiss, A | 1 |
| Hensel, M | 1 |
| Goerner, R | 1 |
| Khbeis, T | 1 |
| Hohaus, S | 1 |
| Egerer, G | 1 |
| Solomayer, E | 1 |
| Haas, R | 1 |
| Grischke, EM | 1 |
| Bastert, G | 1 |
| Takasawa, H | 1 |
| Okada, K | 1 |
| Ueki, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Phase-III Trial of the Cooperative Weichteilsarkom Study Group (CWS) for Localised High-risk Rhabdomyosarcoma and Localised Rhabdomyosarcoma-like Soft Tissue Sarcoma in Children, Adolescents, and Young Adults[NCT00876031] | Phase 3 | 195 participants (Actual) | Interventional | 2009-07-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for thiotepa and Soft Tissue Neoplasms
| Article | Year |
|---|---|
Treatment of children with metastatic soft tissue sarcoma with oral maintenance compared to high dose chemotherapy: report of the HD CWS-96 trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cyclophosphami | 2008 |
A phase II study of two cycles of high-dose chemotherapy with autologous stem cell support in patients with metastatic breast cancer who meet eligibility criteria for a single cycle.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carboplatin | 2000 |
3 other studies available for thiotepa and Soft Tissue Neoplasms
| Article | Year |
|---|---|
[High-dose chemotherapy with autologous peripheral blood stem cell transplantation (PBSCT) for refractory bone and soft tissue sarcomas].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Busulfan; Child; | 1999 |
Comparison of double and triple high-dose chemotherapy with autologous blood stem cell transplantation in patients with metastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Dose-Response | 2001 |
[A calvalial metastasis of alveolar soft part sarcoma (author's transl)].
Topics: Adolescent; Arm; Cyclophosphamide; Female; Humans; Lung Neoplasms; Neoplasm Metastasis; Radiography; | 1976 |