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thiotepa and Skin Diseases

thiotepa has been researched along with Skin Diseases in 5 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Skin Diseases: Diseases involving the DERMIS or EPIDERMIS.

Research Excerpts

ExcerptRelevanceReference
"Mitomycin C 40 mg in 40 ml water was administered intravesically every week for 8 consecutive weeks to 60 patients with superficial bladder cancer."7.67Mitomycin C intravesical therapy in noninvasive bladder cancer after failure on thiotepa. ( Block, NL; Brannen, G; Cummings, KB; Flanagan, M; Issell, BF; Levin, EA; Prout, GR; Soloway, MS; Summers, JL; Veenema, R, 1984)
"High-dose thiotepa, a polyfunctional alkylating agent used in the treatment of solid tumors in children and adults, has been reported to cause a variety of reactions in the skin, including erythema, blistering, and hyperpigmentation."3.74Cutaneous effects of thiotepa in pediatric patients receiving high-dose chemotherapy with autologous stem cell transplantation. ( Bayliss, SJ; Hayashi, RJ; Lloyd, BM; Rosman, IS, 2008)
"Mitomycin C 40 mg in 40 ml water was administered intravesically every week for 8 consecutive weeks to 60 patients with superficial bladder cancer."3.67Mitomycin C intravesical therapy in noninvasive bladder cancer after failure on thiotepa. ( Block, NL; Brannen, G; Cummings, KB; Flanagan, M; Issell, BF; Levin, EA; Prout, GR; Soloway, MS; Summers, JL; Veenema, R, 1984)
"Radiation pneumonitis was observed in 5 patients (7%), 4 of whom had undergone high-dose chemotherapy (P = 0."2.68The toxicity of radiotherapy following high-dose chemotherapy with peripheral blood stem cell support in high-risk breast cancer: a preliminary analysis. ( Baars, JW; Beijnen, JH; Borger, JH; Richel, DJ; Rodenhuis, S; Rutgers, EJ; Schaake-Koning, CC; Schornagel, JH; van der Wall, E; van Zandwijk, N, 1996)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KENIS, Y2
VAN DER MEIREN, L2
Rosman, IS1
Lloyd, BM1
Hayashi, RJ1
Bayliss, SJ1
Issell, BF1
Prout, GR1
Soloway, MS1
Cummings, KB1
Brannen, G1
Veenema, R1
Flanagan, M1
Block, NL1
Summers, JL1
Levin, EA1
van der Wall, E1
Schaake-Koning, CC1
van Zandwijk, N1
Baars, JW1
Schornagel, JH1
Richel, DJ1
Rutgers, EJ1
Borger, JH1
Beijnen, JH1
Rodenhuis, S1
Greenspan, EM1
Jaffrey, I1
Bruckner, H1

Trials

1 trial available for thiotepa and Skin Diseases

ArticleYear
The toxicity of radiotherapy following high-dose chemotherapy with peripheral blood stem cell support in high-risk breast cancer: a preliminary analysis.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:9

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin

1996

Other Studies

4 other studies available for thiotepa and Skin Diseases

ArticleYear
[Poikilodermic state; Hodgkin's disease of skin and ganglia, treatment by triethylenethiophosphoramide].
    Archives belges de dermatologie et de syphiligraphie, 1956, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Ganglia; Hodgkin Disease; Humans; Parapsoriasis; Skin; Skin Diseases; Thiotep

1956
[Poikilodermic state; Hodgkin's disease of skin and ganglia, treatment by triethylenethiophosphoramide].
    Archives belges de dermatologie et de syphiligraphie, 1956, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Ganglia; Hodgkin Disease; Humans; Parapsoriasis; Skin; Skin Diseases; Thiotep

1956
[Poikilodermic state; Hodgkin's disease of skin and ganglia, treatment by triethylenethiophosphoramide].
    Archives belges de dermatologie et de syphiligraphie, 1956, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Ganglia; Hodgkin Disease; Humans; Parapsoriasis; Skin; Skin Diseases; Thiotep

1956
[Poikilodermic state; Hodgkin's disease of skin and ganglia, treatment by triethylenethiophosphoramide].
    Archives belges de dermatologie et de syphiligraphie, 1956, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Ganglia; Hodgkin Disease; Humans; Parapsoriasis; Skin; Skin Diseases; Thiotep

1956
Cutaneous effects of thiotepa in pediatric patients receiving high-dose chemotherapy with autologous stem cell transplantation.
    Journal of the American Academy of Dermatology, 2008, Volume: 58, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclopho

2008
Mitomycin C intravesical therapy in noninvasive bladder cancer after failure on thiotepa.
    Cancer, 1984, Mar-01, Volume: 53, Issue:5

    Topics: Adult; Aged; Drug Evaluation; Humans; Inflammation; Middle Aged; Mitomycin; Mitomycins; Skin Disease

1984
Thiotepa, cutaneous reactions, and efficacy.
    JAMA, 1977, May-23, Volume: 237, Issue:21

    Topics: Female; Humans; Methotrexate; Ovarian Neoplasms; Skin Diseases; Thiotepa

1977
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