thiotepa has been researched along with Scleritis in 1 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Scleritis: Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pterygium excision was complicated by bacterial corneoscleritis and endophthalmitis in two patients, one who had received postoperative beta irradiation and the other topical thiotepa." | 3.67 | Bacterial corneoscleritis complicating pterygium excision. ( Farrell, PL; Smith, RE, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farrell, PL | 1 |
| Smith, RE | 1 |
1 other study available for thiotepa and Scleritis
| Article | Year |
|---|---|
Bacterial corneoscleritis complicating pterygium excision.
Topics: Adult; Aged; Beta Particles; Combined Modality Therapy; Endophthalmitis; Female; Humans; Keratitis; | 1989 |