Page last updated: 2024-11-05

thiotepa and Sarcoma 180

thiotepa has been researched along with Sarcoma 180 in 18 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Sarcoma 180: An experimental sarcoma of mice.

Research Excerpts

ExcerptRelevanceReference
" Pharmacokinetic studies have shown that these compounds possess particular affinity towards tumor tissue."1.26Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs. ( Djachkovskaya, RF; Emanuel, NM; Konovalova, NP, 1976)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199018 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BACK, N1
AMBRUS, JL1
STANISLAVSKAIA, MS1
CHORIN, VA1
ROSSOLIMO, OK1
GOLDBERG, LE1
STANISLAVSKAYA, MS1
BLUMBERG, NA1
VERTOGRADOVA, TP1
GERICKE, D1
Tret'iakov, AV1
Iaremenko, KV1
Eremeeva, AA1
Tereshin, IM1
Emanuel, NM1
Konovalova, NP1
Djachkovskaya, RF1
Robinson, E1
Mekori, T1
Potopal'skiĭ, AI1
Shishka, GV1
Iordan, AM1
Merkulov, MF2
Leskova, SG2
Kanzawa, F1
Hoshi, A1
Kuretani, K1
Bulbuk, GA1
Noell, CW1
Cheng, CC1
Calcutt, G1
Anisimov, VN1
Terent'eva, TG1
Fomina, IP1
Navashin, SM1
Maliugina, LL1
Pol'kina, RI1
Remizov, AL1
Petrov, AS1
Kraĭz, BO1
Shelaputina, ZF1
Iavorskaia, NP1

Other Studies

18 other studies available for thiotepa and Sarcoma 180

ArticleYear
Effect of oxygen tension on the sensitivity of normal and tumor tissues to alkylating agents.
    Journal of the National Cancer Institute, 1963, Volume: 30

    Topics: Alkylating Agents; Animals; Busulfan; Chlorambucil; Mechlorethamine; Oxygen; Sarcoma 180; Thiotepa;

1963
[EXPERIMENTAL STUDIES ON THE ANTINEOPLASTIC EFFECT OF OLIVOMYCIN IN ASSOCIATION WITH SOME SYNTHETIC CYTOSTATIC DRUGS IN CROCKER'S SARCOMA].
    Antibiotiki, 1963, Volume: 8

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Busulfan; Cytost

1963
EXPERIMENTAL STUDY OF OLIVOMYCIN, AN ANTITUMOUR ANTIBIOTIC.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Carcin

1964
[EXPERIENCE WITH ETHYLENEIMINES].
    Neoplasma, 1964, Volume: 11

    Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Leukemi

1964
[High sexual selectivity of hydrazine derivatives potentiating the antitumor effect of cytostatics].
    Doklady Akademii nauk SSSR, 1978, Volume: 243, Issue:2

    Topics: Animals; Barbital; Barbiturates; Castration; Cortisone; Diethylstilbestrol; Drug Combinations; Drug

1978
[Potentiation of the antitumor action of alkylating compounds by amphotericin B].
    Antibiotiki, 1977, Volume: 22, Issue:2

    Topics: Alkylating Agents; Amphotericin B; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cycloph

1977
Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs.
    Cancer treatment reports, 1976, Volume: 60, Issue:11

    Topics: Adenocarcinoma; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinic

1976
Combinations of the effect of radiotherapy, alkylating agents and phytohemagglutinin on sarcoma 180 in Swiss mice.
    European journal of cancer, 1973, Volume: 9, Issue:2

    Topics: Animals; Cyclophosphamide; Lectins; Male; Mice; Sarcoma 180; Thiotepa

1973
[Antitumor action of berberinol thiophosphamide in experimental tumors in mice].
    Voprosy onkologii, 1974, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma, Ehrlich Tumor; Dose-Response Relationship, Drug; Fe

1974
[Use of transplantability indices of tumor cells for evaluation of the cytotoxic effect of antineoplastic agents in vitro].
    Farmakologiia i toksikologiia, 1972, Volume: 35, Issue:1

    Topics: Animals; Cell Line; Cells, Cultured; Culture Media; Fluorouracil; Leukemia, Experimental; Male; Melp

1972
Antitumor activity of haloacetylphenothiazines against ascites sarcoma-180.
    Gan, 1972, Volume: 63, Issue:2

    Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Iodoacetates; Mice; Neoplasm Tra

1972
[The state of parietal carbohydrate hydrolysis following a single administration of antitumor drugs to intact and tumorous animals].
    Voprosy onkologii, 1972, Volume: 18, Issue:12

    Topics: Animals; Carcinoma; Cyclophosphamide; Digestion; Female; Fluorouracil; Furans; Hydrolysis; Intestine

1972
Anticancer activity of P,P-bis(2-methyl-1-aziridinyl)-N-2-pyrimidinylphosphinic amide (methylphosphazine) and related compounds.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:1

    Topics: Adenocarcinoma; Amides; Animals; Antineoplastic Agents; Azirines; Carcinoma 256, Walker; Cyclophosph

1968
Enhanced growth of transplanted tumours after treatment with cytotoxic agents.
    Biochemical pharmacology, 1968, Volume: 17, Issue:8

    Topics: Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Ethers, Cyclic; Lymphoma; Mannomustine; Meth

1968
[On the anti-tumor action of N,N'-malonyl-bis-ethyleneimine].
    Voprosy onkologii, 1967, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Injections, Intraperitoneal; Mice; Rats; S

1967
[Experimental study of the antineoplastic effect of the antibiotic polymycin].
    Antibiotiki, 1970, Volume: 15, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antifungal Agents; Antiviral Agents; As

1970
[The anti-tumor effect of several mono- and di-chlor-sym.triazine derivatives].
    Voprosy onkologii, 1970, Volume: 16, Issue:6

    Topics: Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Female; Leukopenia; Lung Neoplasms; Lympho

1970
[Effect of thiophosphamide on the incorporation of H3-thymidine into the DNA of cells of surviving transplantable tumor sections sensitive and resistant toward the agent].
    Farmakologiia i toksikologiia, 1971, Volume: 34, Issue:1

    Topics: Animals; Body Weight; Depression, Chemical; DNA, Neoplasm; In Vitro Techniques; Male; Mice; Rats; Sa

1971