thiotepa has been researched along with Rhabdoid Tumor in 3 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Rhabdoid Tumor: A rare but highly lethal childhood tumor found almost exclusively in infants. Histopathologically, it resembles RHABDOMYOSARCOMA but the tumor cells are not of myogenic origin. Although it arises primarily in the kidney, it may be found in other parts of the body. The rhabdoid cytomorphology is believed to be the expression of a very primitive malignant cell. (From Holland et al., Cancer Medicine, 3d ed, p2210)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment for malignant embryonal brain tumors in young children usually employs cycles of standardly dosed cisplatinum followed by high-dose carboplatinum-containing conditioning with single or tandem autologous stem cell rescue (HDC-ASCR)." | 1.56 | Changes in glomerular filtration rate and clinical course after sequential doses of carboplatin in children with embryonal brain tumors undergoing autologous stem cell transplantation. ( Almutereen, M; Elborai, Y; Hafez, H; Lee, MA; Lehmann, L; Maher, OM, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Elborai, Y | 1 |
| Almutereen, M | 1 |
| Maher, OM | 1 |
| Hafez, H | 1 |
| Lee, MA | 1 |
| Lehmann, L | 1 |
| Fidani, P | 1 |
| De Ioris, MA | 1 |
| Serra, A | 1 |
| De Sio, L | 1 |
| Ilari, I | 1 |
| Cozza, R | 1 |
| Boldrini, R | 1 |
| Milano, GM | 1 |
| Garrè, ML | 1 |
| Donfrancesco, A | 1 |
| Park, ES | 1 |
| Sung, KW | 1 |
| Baek, HJ | 1 |
| Park, KD | 1 |
| Park, HJ | 1 |
| Won, SC | 1 |
| Lim, DH | 1 |
| Kim, HS | 1 |
2 trials available for thiotepa and Rhabdoid Tumor
| Article | Year |
|---|---|
A multimodal strategy based on surgery, radiotherapy, ICE regimen and high dose chemotherapy in atypical teratoid/rhabdoid tumours: a single institution experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Child, Preschoo | 2009 |
Tandem high-dose chemotherapy and autologous stem cell transplantation in young children with atypical teratoid/rhabdoid tumor of the central nervous system.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Child | 2012 |
1 other study available for thiotepa and Rhabdoid Tumor
| Article | Year |
|---|---|
Changes in glomerular filtration rate and clinical course after sequential doses of carboplatin in children with embryonal brain tumors undergoing autologous stem cell transplantation.
Topics: Acute Kidney Injury; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ca | 2020 |